Patents Assigned to PULMOCIDE LIMITED
  • Process for preparing a compound useful to treat mycoses
    Patent number: 12269814
    Abstract: A combination therapy including one or more compounds of formula (I): wherein R represents hydrogen, halo, cyano, C1-4 haloalkyl, C1-4 haloalkoxy, or SO2NR5R6, R1a and R1b independently represent hydrogen or halo; R2 represents hydrogen, halo, cyano, C1-4 alkyl, C1-4 alkoxy, or C1-4 haloalkoxy; R3 represents halo, cyano, C1-4 alkyl, or C1-4 hydroxyalkyl; R4 represents hydrogen or C1-4 alkyl; X represents CH or N; Y represents N or CH which carbon atom may optionally be substituted by R, R1a or R1b; R5 and R6 independently represent hydrogen or C1-4 alkyl; or a pharmaceutically acceptable salt thereof; and a second or further active ingredient.
    Type: Grant
    Filed: April 18, 2023
    Date of Patent: April 8, 2025
    Assignee: PULMOCIDE LIMITED
    Inventors: Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong, Peter John Murray, Stuart Thomas Onions, Mihiro Sunose
  • PROCESS FOR PREPARING A COMPOUND USEFUL TO TREAT MYCOSES
    Publication number: 20230295133
    Abstract: A process for preparing a compound of formula (II): includes reacting a compound of formula (VIII): with a compound of formula (XIV):
    Type: Application
    Filed: April 18, 2023
    Publication date: September 21, 2023
    Applicant: PULMOCIDE LIMITED
    Inventors: Thomas Christopher COLLEY, Kazuhiro ITO, Garth RAPEPORT, Peter STRONG, Peter John MURRAY, Stuart Thomas ONIONS, Mihiro SUNOSE
  • Process for preparing a compound useful to treat mycoses
    Patent number: 11661415
    Abstract: A process for preparing a compound of formula (II): includes reacting a compound of formula (VIII): with a compound of formula (XIV):
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: May 30, 2023
    Assignee: PULMOCIDE LIMITED
    Inventors: Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong, Peter John Murray, Stuart Thomas Onions, Mihiro Sunose
  • POLYMORPHS OF TRIAZOLE ANTIFUNGAL COMPOUND PC945
    Publication number: 20230028714
    Abstract: The invention relates to crystalline polymorphic manifestations of a compound of formula (I) and related aspects.
    Type: Application
    Filed: December 4, 2020
    Publication date: January 26, 2023
    Applicant: Pulmocide Limited
    Inventors: Christopher John WALLIS, Gerald STEELE, Suzanne BUTTAR, Osama SULEIMAN, Julian NORTHEN, John MYKYTIUK, Jamie MARSHALL
  • PROCESS FOR PREPARING A COMPOUND OF FORMULA (XIII)
    Publication number: 20210238169
    Abstract: This invention relates to a process for preparing the compound of formula (XIII).
    Type: Application
    Filed: April 14, 2021
    Publication date: August 5, 2021
    Applicant: PULMOCIDE LIMITED
    Inventors: MIHIRO SUNOSE, THOMAS CHRISTOPHER COLLEY, KAZUHIRO ITO, GARTH RAPEPORT, PETER STRONG
  • Compounds which are used in the preparation of the compound of formula (I)
    Patent number: 11008307
    Abstract: This invention relates to compounds which are used in the preparation of the compound of formula (I).
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: May 18, 2021
    Assignee: PULMOCIDE LIMITED
    Inventors: Mihiro Sunose, Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong
  • PROCESS FOR PREPARING A COMPOUND USEFUL TO TREAT MYCOSES
    Publication number: 20210048874
    Abstract: A process for preparing a compound of formula (II): includes reacting a compound of formula (VIII): with a compound of formula (XIV):
    Type: Application
    Filed: November 4, 2020
    Publication date: February 18, 2021
    Applicant: PULMOCIDE LIMITED
    Inventors: Thomas Christopher COLLEY, Kazuhiro ITO, Garth RAPEPORT, Peter STRONG, Peter John MURRAY, Stuart Thomas ONIONS, Mihiro SUNOSE
  • COMPOUNDS WHICH ARE USED IN THE PREPARATION OF THE COMPOUND OF FORMULA (I)
    Publication number: 20200399253
    Abstract: This invention relates to compounds which are used in the preparation of the compound of formula (I).
    Type: Application
    Filed: September 4, 2020
    Publication date: December 24, 2020
    Applicant: PULMOCIDE LIMITED
    Inventors: MIHIRO SUNOSE, THOMAS CHRISTOPHER COLLEY, KAZUHIRO ITO, GARTH RAPEPORT, PETER STRONG
  • Process for preparing a compound useful to treat mycoses
    Patent number: 10858345
    Abstract: A process for preparing a compound of formula (II): includes reacting a compound of formula (VIII): with a compound of formula (XIV):
    Type: Grant
    Filed: April 15, 2020
    Date of Patent: December 8, 2020
    Assignee: PULMOCIDE LIMITED
    Inventors: Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong, Peter John Murray, Stuart Thomas Onions, Mihiro Sunose
  • Compounds which are used in the preparation of the compound of formula (II)
    Patent number: 10800762
    Abstract: This invention relates to compounds which are used in the preparation of the compound of formula (II).
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: October 13, 2020
    Assignee: PULMOCIDE LIMITED
    Inventors: Mihiro Sunose, Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong
  • PROCESS FOR PREPARING A COMPOUND USEFUL TO TREAT MYCOSES
    Publication number: 20200239453
    Abstract: A process for preparing a compound of formula (I): includes reacting a compound of formula (II): with a compound of formula (III):
    Type: Application
    Filed: April 15, 2020
    Publication date: July 30, 2020
    Applicant: PULMOCIDE LIMITED
    Inventors: Thomas Christopher COLLEY, Kazuhiro ITO, Garth RAPEPORT, Peter STRONG, Peter John MURRAY, Stuart Thomas ONIONS, Mihiro SUNOSE
  • Process for preparing a compound useful to treat mycoses
    Patent number: 10662179
    Abstract: A process for preparing a compound of formula (I): includes reacting a compound of formula (II): with a compound of formula (III):
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: May 26, 2020
    Assignee: PULMOCIDE LIMITED
    Inventors: Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong, Peter John Murray, Stuart Thomas Onions, Mihiro Sunose
  • Compounds
    Patent number: 10626126
    Abstract: There are provided 5,6-dihydro-4H-dithieno[3,2-b:2?,3?-d]azepine derivatives(as defined in the disclosure) which are useful in the treatment of RSV infection and for the prevention of disease associated with RSV infection.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: April 21, 2020
    Assignee: PULMOCIDE LIMITED
    Inventors: Simon Fraser Hunt, Stuart Thomas Onions, Vladimir Sherbukhin, Euan Alexander Fraser Fordyce, Jennifer Claire Thomas, Peter John Murray, Matthew Stephen Coates, Daniel William Brookes, Kazuhiro Ito, Peter Strong
  • COMPOUNDS WHICH ARE USED IN THE PREPARATION OF THE COMPOUND OF FORMULA (II)
    Publication number: 20200031809
    Abstract: This invention relates to compounds which are used in the preparation of the compound of formula (II).
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Applicant: PULMOCIDE LIMITED
    Inventors: MIHIRO SUNOSE, THOMAS CHRISTOPHER COLLEY, KAZUHIRO ITO, GARTH RAPEPORT, PETER STRONG
  • COMPOUND USEFUL TO TREAT MYCOSES
    Publication number: 20200002320
    Abstract: A compound of formula (II): or a compound of formula (IV): or a compound of formula (XX): is useful in the treatment of mycoses.
    Type: Application
    Filed: September 12, 2019
    Publication date: January 2, 2020
    Applicant: PULMOCIDE LIMITED
    Inventors: Thomas Christopher COLLEY, Kazuhiro ITO, Garth RAPEPORT, Peter STRONG, Peter John MURRAY, Stuart Thomas ONIONS, Mihiro SUNOSE
  • Aqueous suspension formulation comprising 4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluoro-phenyl)tetrahydrofuran-3-yl)methoxy)-3-methylphenyl) or a pharmaceutically acceptable salt thereof
    Patent number: 10513511
    Abstract: The invention relates to aqueous suspension formulations of compounds, as defined in the specification and as represented by the compound of formula (I): and to their use in therapy.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: December 24, 2019
    Assignee: PULMOCIDE LIMITED
    Inventors: Thomas Christopher Colley, Kazuhiro Ito, Peter Strong, Mihiro Sunose, Matthew McConville
  • Compounds which are used in the preparation of the compound of formula (I)
    Patent number: 10487073
    Abstract: This invention relates to compounds which are used in the preparation of the compound of formula (I).
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: November 26, 2019
    Assignee: PULMOCIDE LIMITED
    Inventors: Mihiro Sunose, Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong
  • 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative
    Patent number: 10472375
    Abstract: There is provided a 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative which is useful in the treatment of respiratory syncytial virus (RSV) infection and for the prevention of disease associated with RSV infection. (Formula (I)).
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: November 12, 2019
    Assignee: PULMOCIDE LIMITED
    Inventors: Simon Fraser Hunt, Stuart Thomas Onions, Vladimir Sherbukhin, Euan Alexander Fraser Fordyce, Peter John Murray, Daniel William Brookes, Kazuhiro Ito, Peter Strong, Matthew Stephen Coates
  • Compound useful to treat mycoses
    Patent number: 10450304
    Abstract: A compound of formula (II): or a compound of formula (IV): or a compound of formula (XX): is useful in the treatment of mycoses.
    Type: Grant
    Filed: May 24, 2019
    Date of Patent: October 22, 2019
    Assignee: PULMOCIDE LIMITED
    Inventors: Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong, Peter John Murray, Stuart Thomas Onions, Mihiro Sunose
  • COMPOUND USEFUL TO TREAT MYCOSES
    Publication number: 20190276441
    Abstract: A compound of formula (II): or a compound of formula (IV): or a compound of formula (XX): is useful in the treatment of mycoses.
    Type: Application
    Filed: May 24, 2019
    Publication date: September 12, 2019
    Applicant: PULMOCIDE LIMITED
    Inventors: Thomas Christopher COLLEY, Kazuhiro ITO, Garth RAPEPORT, Peter STRONG, Peter John MURRAY, Stuart Thomas ONIONS, Mihiro SUNOSE