Abstract: A process for preparing a compound of formula (I): or a pharmaceutically acceptable salt thereof includes reacting a compound of formula (6): (wherein R is H) with 2-aminocyclohexanol or a salt thereof.
Type:
Application
Filed:
March 20, 2019
Publication date:
July 4, 2019
Applicant:
PULMOCIDE LIMITED
Inventors:
Thomas Christopher COLLEY, Kazuhiro ITO, Peter STRONG, Mihiro SUNOSE, Matthew McCONVILLE
Abstract: A process for preparing a compound of formula (I): or a pharmaceutically acceptable salt thereof includes reacting a compound of formula (6): (wherein R is H) with 2-aminocyclohexanol or a salt thereof.
Type:
Grant
Filed:
May 4, 2018
Date of Patent:
May 7, 2019
Assignee:
PULMOCIDE LIMITED
Inventors:
Thomas Christopher Colley, Kazuhiro Ito, Peter Strong, Mihiro Sunose, Matthew McConville
Abstract: There is provided a 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative which is useful in the treatment of respiratory syncytial virus (RSV) infection and for the prevention of disease associated with RSV infection. (Formula (1)).
Type:
Grant
Filed:
July 12, 2018
Date of Patent:
April 30, 2019
Assignee:
PULMOCIDE LIMITED
Inventors:
Simon Fraser Hunt, Stuart Thomas Onions, Vladimir Sherbukhin, Euan Alexander Fraser Fordyce, Peter John Murray, Daniel William Brookes, Kazuhiro Ito, Peter Strong, Matthew Stephen Coates
Abstract: There are provided 5,6-dihydro-4H-dithieno[3,2-b:2?,3?-d]azepine derivatives (as defined in the disclosure) which are useful in the treatment of RSV infection and for the prevention of disease associated with RSV infection.
Type:
Application
Filed:
April 7, 2017
Publication date:
March 28, 2019
Applicant:
Pulmocide Limited
Inventors:
Simon Fraser HUNT, Stuart Thomas ONIONS, Vladimir SHERBUKHIN, Euan Alexander Fraser FORDYCE, Jennifer Claire THOMAS, Peter John MURRAY, Matthew Stephen COATES, Daniel William BROOKES, Kazuhiro ITO, Peter STRONG
Abstract: There are provided 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivatives which are useful in the treatment of respiratory syncytial virus (RSV) infection and for the prevention of disease associated with RSV infection.
Type:
Grant
Filed:
October 8, 2015
Date of Patent:
January 29, 2019
Assignee:
PULMOCIDE LIMITED
Inventors:
Simon Fraser Hunt, Stuart Thomas Onions, Vladimir Sherbukhin, Euan Alexander Fraser Fordyce, Peter John Murray, Matthew Stephen Coates, Daniel William Brookes, Kazuhiro Ito, Peter Strong
Abstract: There are provided inter alia compounds which are intended to treat or prevent respiratory syncytial virus infections and associated disease particularly infections caused by the A and B strains thereof.
Type:
Grant
Filed:
December 18, 2015
Date of Patent:
December 25, 2018
Assignee:
PULMOCIDE LIMITED
Inventors:
Euan Alexander Fraser Fordyce, Simon Fraser Hunt, Stuart Thomas Onions, Vladimir Sherbukhin, Matthew Stephen Coates, Daniel William Brookes, Kazuhiro Ito, Peter Strong, John King-Underwood
Abstract: This invention relates to compounds, as defined in the specification and as represented by the compound of formula (I): that are useful in the treatment of mycoses, compositions containing them and their use in therapy.
Type:
Grant
Filed:
December 4, 2015
Date of Patent:
October 23, 2018
Assignee:
PULMOCIDE LIMITED
Inventors:
Thomas Christopher Colley, Kazuhiro Ito, Garth Rapeport, Peter Strong, Peter John Murray, Stuart Thomas Onions, Mihiro Sunose
Abstract: There is provided a 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative which is useful in the treatment of respiratory syncytial virus (RSV) infection and for the prevention of disease associated with RSV infection. (Formula (1)).
Type:
Grant
Filed:
February 22, 2018
Date of Patent:
July 31, 2018
Assignee:
PULMOCIDE LIMITED
Inventors:
Simon Fraser Hunt, Stuart Thomas Onions, Vladimir Sherbukhin, Euan Alexander Fraser Fordyce, Peter John Murray, Daniel William Brookes, Kazuhiro Ito, Peter Strong
Abstract: This invention relates to compounds, as defined in the specification and as represented by the compound of formula (I): that are useful in the treatment of mycoses, to compositions containing them and to their use in therapy.
Type:
Grant
Filed:
November 9, 2016
Date of Patent:
May 15, 2018
Assignee:
PULMOCIDE LIMITED
Inventors:
Thomas Christopher Colley, Kazuhiro Ito, Peter Strong, Mihiro Sunose, Matthew McConville
Abstract: There is provided a 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative which is useful in the treatment of respiratory syncytial virus (RSV) infection and for the prevention of disease associated with RSV infection. (Formula (1)).
Type:
Grant
Filed:
July 6, 2017
Date of Patent:
March 27, 2018
Assignee:
PULMOCIDE LIMITED
Inventors:
Simon Fraser Hunt, Stuart Thomas Onions, Vladimir Sherbukhin, Euan Alexander Fraser Fordyce, Peter John Murray, Daniel William Brookes, Kazuhiro Ito, Peter Strong
Abstract: There are provided inter alia compounds which are intended to treat or prevent respiratory syncytial virus infections and associated disease particularly infections caused by the A and B strains thereof.
Type:
Application
Filed:
December 18, 2015
Publication date:
December 14, 2017
Applicant:
PULMOCIDE LIMITED
Inventors:
Euan Alexander Fraser FORDYCE, Simon Fraser HUNT, Stuart Thomas ONIONS, Vladimir SHERBUKHIN, Matthew Stephen COATES, Daniel William BROOKES, Kazuhiro ITO, Peter STRONG, John KING-UNDERWOOD
Abstract: There is provided a 5,6-dihydro-4H-benzo[b]thieno-[2,3-d]azepine derivative which is useful in the treatment of respiratory syncytial virus (RSV) infection and for the prevention of disease associated with RSV infection. (Formula (1)).
Type:
Grant
Filed:
October 8, 2015
Date of Patent:
August 15, 2017
Assignee:
PULMOCIDE LIMITED
Inventors:
Simon Fraser Hunt, Stuart Thomas Onions, Vladimir Sherbukhin, Euan Alexander Fordyce, Peter John Murray, Daniel William Brookes, Kazuhiro Ito, Peter Strong