Patents Assigned to Purdue Research
  • Patent number: 12278186
    Abstract: A method of providing a barrier to diffusion of metal into a dielectric in a metal interconnect arrangement is disclosed which includes forming a damascene trench, including forming a dielectric base, with a trench made therein, depositing one or more two dimensional diffusion barrier layers formed over the trench, depositing a conductor layer formed atop the diffusion layer, wherein the one or more two-dimensional diffusion barrier layers substantially prevent diffusion of constituents of the conductor layer into the dielectric base, wherein each of the one or more two-dimensional diffusion barrier layers is a polycrystalline material selected from the group consisting of TaSex, TaTex, TiSx, TiSex, TiTex, and TaSx, and wherein x is between 1.5-1.9.
    Type: Grant
    Filed: February 27, 2022
    Date of Patent: April 15, 2025
    Assignee: Purdue Research Foundation
    Inventors: Zhihong Chen, Chun-Li Lo
  • Patent number: 12274879
    Abstract: An arrangement for reducing intraocular pressure includes a pulse signal source, a probe coupling, and at least one electrode. The probe coupling is configured to be supported on a portion of a living eye. The electrodes are supported on the probe coupling. The electrodes are operably coupled to receive a pulse signal from the pulse signal source.
    Type: Grant
    Filed: July 6, 2023
    Date of Patent: April 15, 2025
    Assignees: Purdue Research Foundation, The Jackson Laboratory
    Inventors: Pedro Irazoqui, Simon John, Alex Kokini, Adam Willats, Alexander Chelminski, Matt Matuscak, Gabriel Simon
  • Publication number: 20250114458
    Abstract: A method of providing an edible printer dye for use as a predetermined pattern including a stealth quick response (QR) code taggant for an ingestible food or pharmaceutical product includes dissolving one or more edible infrared (IR) or near IR (NIR) light absorbing dyes in a carrier solution based on a predetermined concentration of the one or more IR or NIR light absorbing dyes, thereby generating an IR or NIR light absorbing dye solution, adding a mixture of dispersing agents to the dye solution, thereby generating an edible IR or NIR light absorbing dyes, loading the edible IR or NIR light absorbing dyes in any one of a printer cannisters, and loading other visible edible dyes in corresponding other printer cannisters.
    Type: Application
    Filed: September 14, 2024
    Publication date: April 10, 2025
    Applicant: Purdue Research Foundation
    Inventors: Young Kim, Joshua Kim, Jungwoo Leem
  • Publication number: 20250116441
    Abstract: System and methods for oil circulation ratio (OCR) sensing with a suction-line accumulator are provided. The accumulator may include a sensor configured to detect the level of oil. The accumulator may further include a valve which opens when oil is at a high-level and closes when oil is at a low-level. The valve may release accumulated oil into the suction-line based on a level-sensor inside the accumulator.
    Type: Application
    Filed: December 19, 2024
    Publication date: April 10, 2025
    Applicant: Purdue Research Foundation
    Inventors: Eckhard Achim Groll, James Edward Braun, Orkan Kurtulus, Parveen Dhillon, Vatsal Manilal Shah
  • Publication number: 20250115636
    Abstract: Peptidomimetic inhibitors of protein N-terminal methyltransferase 1, such as a compound with the following formula: a composition comprising same, and a method of use.
    Type: Application
    Filed: December 2, 2022
    Publication date: April 10, 2025
    Applicant: Purdue Research Foundation
    Inventors: Rong Huang, Dongxing Chen, Guangping Dong
  • Patent number: 12269862
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells wherein the CAR T cells comprise a CAR and the CAR comprises an E2 anti-fluorescein antibody fragment, and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: August 31, 2023
    Date of Patent: April 8, 2025
    Assignees: Endocyte, Inc., Purdue Research Foundation, Seattle Children's Hospital
    Inventors: Philip Stewart Low, Haiyan Chu, Yingjuan June Lu, Christopher Paul Leamon, Leroy W. Wheeler, II, Michael C. Jensen, James Matthaei
  • Patent number: 12269908
    Abstract: This invention relates to a method for manufacturing a catechol-containing co-polymer through a suspension polymerization or a solution polymerization process. In some illustrative embodiments, this disclosure relates to a process of a free radical suspension polymerization for large-scale manufacturing catechol-containing copolymers. In some other illustrative embodiments, this disclosure relates to a solution polymerization of free radical, cationic, or anionic process for large-scale manufacturing catechol-containing copolymers. The process and the product thereof are within the scope of this disclosure.
    Type: Grant
    Filed: December 17, 2020
    Date of Patent: April 8, 2025
    Assignee: Purdue Research Foundation
    Inventors: Jonathan J. Wilker, Samuel L. Huntington, Amelia A. Putnam
  • Patent number: 12270755
    Abstract: Provided are methods, devices, and systems for identifying the concentration of delta-9-tetrahydrocannabinol (?-9 THC) in a given sample. The system allows for in situ formation of a chromophore eliminating the use of chloroform, wherein said chromophore absorbance spectra is measured using a spectroscopy method within a light wavelength range. The system allows for calculating the concentration of ?-9 THC using the linear relationship between the ?-9 THC level and the intensity of the color change in the present tester. Said linear relationship is obtained because the tester of the present disclosure allows the chromophore formation reaction go to completion.
    Type: Grant
    Filed: November 6, 2020
    Date of Patent: April 8, 2025
    Assignee: Purdue Research Foundation
    Inventor: Charles A. Steele
  • Patent number: 12266273
    Abstract: An augmented reality system for developing and providing augmented reality learning experiences is disclosed. The augmented reality system advantageously combines augmented reality with the capabilities of cloud technology to provide a pull-based collaborative model, in which students and instructors collaborate by uploading, sharing, and downloading augmented reality learning content. The augmented reality system enables students to improve the augmented reality learning content by adding contributions to the original augmented reality learning content that was created by an instructor.
    Type: Grant
    Filed: October 24, 2022
    Date of Patent: April 1, 2025
    Assignee: Purdue Research Foundation
    Inventors: Karthik Ramani, Ana Villanueva Pérez
  • Patent number: 12257217
    Abstract: A composition comprising an active agent that inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT) is provided. With the composition, food intake can be suppressed, and/or body weight can be reduced, and/or metabolic disorders can be prevented and/or treated.
    Type: Grant
    Filed: October 15, 2022
    Date of Patent: March 25, 2025
    Assignee: Purdue Research Foundation
    Inventors: Kee-Hong Kim, Yuyan Zhu
  • Patent number: 12257550
    Abstract: A desalination system, including a membrane distillation portion, a solar power concentration portion, and a thermal vapor compression portion operationally connected to the membrane distillation portion and to the solar power concentration portion. The membrane distillation portion includes a first vessel having a first portion and a second portion separated by a hydrophobic membrane operationally connected therebetween and oriented to pass water from the first portion to the second portion, wherein the hydrophobic membrane further comprises a hydrophilic membrane and an air blocking layer connected to the hydrophilic membrane and disposed in the first portion, a vacuum gap adjacent the hydrophobic membrane and disposed in the second portion, a first fluid inlet and a first fluid outlet operationally connected to the first portion, and a second fluid inlet and a second fluid outlet operationally connected to the second portion.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: March 25, 2025
    Assignee: Purdue Research Foundation
    Inventors: David Warsinger, Abhimanyu Das, Hamid Fattahijuybari, Harsharaj Parmar
  • Publication number: 20250098543
    Abstract: A stretchable transducer includes one or more rectangular sensing regions, each including one or more sensing layers, each including fibrous sensing materials sandwiched between a top and a bottom electrode, two or more substrates adapted to sandwich the one or more sensing layers further forming one or more serpentine regions adapted to allow stretchability of the stretchable transducer, the two or more substrates having axial gaps therebetween, one or more electrical connection regions distally extended longitudinally from the one or more serpentine regions, wherein the one or more electrodes extend longitudinally from the one or more sensing regions through the gaps formed in the serpentine regions and terminating at the one or more electrical connection regions, two clamping regions distally extended longitudinally from the one or more electrical connection regions adapted to provide coupling to the stretchable transducer, and an encasing layer.
    Type: Application
    Filed: September 18, 2024
    Publication date: March 20, 2025
    Applicant: Purdue Research Foundation
    Inventors: Robert A Nawrocki, Jinsheng Fan
  • Publication number: 20250092575
    Abstract: A method of making a stretchable transducer is disclosed. The method includes placing a polymer solution having a concentration (C) in an injectable vessel having an electrically conductive ejection port, applying a voltage (V) between the ejection port and an electrically conductive collection plate a predetermined distance away from the ejection port, ejecting the polymer solution from the injectable vessel at a flow rate (FR), thereby generating a fibrous material having a considerable ?-phase on the collection plate due to electrospinning, removing the fibrous material from the collection plate, depositing conductive electrodes on top and bottom surfaces of the removed fibrous material, thereby generating a transducer, and simultaneously optimizing formation of ?-phase of the fibrous material and yield of the transducer based on unwanted electrical current leakage between deposited electrodes on the top and bottom surfaces based on C, V, and FR.
    Type: Application
    Filed: September 18, 2024
    Publication date: March 20, 2025
    Applicant: Purdue Research Foundation
    Inventors: Robert A. Nawrocki, Jinsheng Fan
  • Patent number: 12253545
    Abstract: System and methods for high accuracy, non-intrusive current sensing are provided. A system may include two magnetic field sensors configured for differential sensing. The system may further include frontend circuitry configured to remove direct current (DC) offset of the magnetic field sensors, upconvert the outputs of the magnetic field sensors, and filter out at least one frequency component from the up-converted signals. The system may receive output signals from the front-end circuitry corresponding to each sensor. The system may further calculate a differential signal based on the output signals. The system may apply optimal detection based on the differential signal and a reference signal to calculate a measurement of current flow. The system may determine a phase angle measurement between the differential signal and the reference signal to calculate a direction of the current flow in the conductor and output various measurement information related to the detected current.
    Type: Grant
    Filed: November 24, 2020
    Date of Patent: March 18, 2025
    Assignee: Purdue Research Foundation
    Inventors: Kaushik Roy, Byunghoo Jung, Chamika Mihiranga Liyanagedera
  • Patent number: 12251439
    Abstract: Provided is a method of reducing a number of viable microbes, including contacting microbes with an antibiotic compound and applying pulses of electricity having a duration of between about 50 nanoseconds and about 900 nanoseconds. The pulses of electricity may have an intensity between about 20 kV/cm and about 40 kV/cm. The pulses of electricity may be applied at a frequency of between about 0.1 Hz and about 10 Hz. The microbes may be a gram-negative or a gram-positive strain of bacteria and the antibiotic may be applied at a concentration for a duration, wherein applying the antibiotic to the strain at the concentration for the duration does not reduce a viable number of bacteria of the strain as much, or at all, when the pulses of electricity are not also applied.
    Type: Grant
    Filed: October 19, 2023
    Date of Patent: March 18, 2025
    Assignees: Purdue Research Foundation, Nanovis, LLC
    Inventors: Allen Lawrence Garner, Ram Anand Vadlamani, David Alan Detwiler
  • Publication number: 20250086985
    Abstract: A method for managing road defects includes capturing images and depth information from a roadway using a first vision system, identifying position of the captured images, processing the captured images by a processing system to i) detect, and ii) classify one or more types of road defects, quantifying the one or more types of road defects to thereby generate quantification parameters by the processing system, and scoring the severity of each of the one or more types of road defects using the processing system that includes a predetermined rule-based scorer based on the generated quantified parameters of the one or more types of road defects.
    Type: Application
    Filed: September 12, 2024
    Publication date: March 13, 2025
    Applicant: Purdue Research Foundation
    Inventors: Mohammad Reza Jahanshahi, Yu-Ting Huang
  • Patent number: 12250869
    Abstract: A perovskite-polymer composite comprising a perovskite and a polymer, wherein the polymer has a structural unit comprising a thiourea (—HN(C?S)NH—) fragment and a (—R1—O—R2—) fragment, wherein R1 and R2 are each independently a C1-C6 alkyl or a cycloalkyl linker; a mechanically robust and self-healable solar cell comprising same; and a method of making same.
    Type: Grant
    Filed: December 1, 2023
    Date of Patent: March 11, 2025
    Assignee: Purdue Research Foundation
    Inventors: Letian Dou, Blake Peter Finkenauer
  • Publication number: 20250073479
    Abstract: A system and method for brain-machine interface communication utilizing Bi-Phasic Quasi-Static Brain Communication (BP-QBC). The system includes a first device and a second device that are in wireless communication together. The system and method include signal transmission between the first device and the second device through dipole coupling. The system is configured to utilize compressive sensing and collision avoidance for enhanced net energy efficiency. The system and method utilize fully electrical quasi-static signaling to militate against energy transduction losses.
    Type: Application
    Filed: November 18, 2024
    Publication date: March 6, 2025
    Applicant: Purdue Research Foundation
    Inventors: Shreyas Sen, Baibhab Chatterjee, Mayukh Nath
  • Patent number: 12239328
    Abstract: The device of the present disclosure is configured for laparoscopic use, particularly to insert a fastener into a plate at an angle of up to 180° from the plane of insertion. The device is further configured to carry a plurality of fasteners, a tightening tool, a cutting device, and tweezers simultaneously to facilitate a rapid procedure while lessening the chance of infection by limiting the amount of times the device must be removed and re-inserted.
    Type: Grant
    Filed: April 23, 2021
    Date of Patent: March 4, 2025
    Assignees: The Trustees of Indiana University, Purdue Research Foundation
    Inventors: Peter Clifton Jenkins, Ramses Martinez
  • Patent number: 12240870
    Abstract: The present disclosure relates to methods of treating a patient with a cancer by administering to the patient a composition comprising CAR T cells and administering to the patient a small molecule linked to a targeting moiety by a linker. The disclosure also relates to compositions for use in such methods.
    Type: Grant
    Filed: February 22, 2019
    Date of Patent: March 4, 2025
    Assignees: Purdue Research Foundation, Endocyte, Inc, Seattle Children's Hospital
    Inventors: Richard Messmann, Christopher Paul Leamon, Haiyan Chu, Yingjuan June Lu, Philip Stewart Low, Michael C. Jensen, James Matthaei, Navin Robert Charles Pinto, Julie Ruggieri Park