Patents Assigned to RareCyte, Inc.
  • Patent number: 10345237
    Abstract: This disclosure relates generally to detecting multiple biomarkers on or within a sample, though more specifically, to detecting individual detection moieties within a plurality of detection moieties.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: July 9, 2019
    Assignee: RareCyte, Inc.
    Inventor: Jeremy Ryan Cooper
  • Patent number: 10330684
    Abstract: This disclosure relates generally to detection and, in particular, to detecting objects within a sample or fraction thereof.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: June 25, 2019
    Assignee: RareCyte, Inc.
    Inventors: Daniel E. Campton, Arturo B. Ramirez, Melinda R. Duplessis
  • Patent number: 10274498
    Abstract: This disclosure relates generally to detection and, in particular, to detecting objects within a sample or fraction thereof.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: April 30, 2019
    Assignee: RareCyte, Inc.
    Inventors: Daniel E. Campton, Arturo B. Ramirez, Melinda R. Duplessis
  • Patent number: 10267805
    Abstract: This disclosure relates generally to detection and, in particular, to detecting objects within a sample or fraction thereof.
    Type: Grant
    Filed: April 5, 2018
    Date of Patent: April 23, 2019
    Assignee: RareCyte, Inc.
    Inventors: Daniel E. Campton, Arturo B. Ramirez
  • Patent number: 10222373
    Abstract: This disclosure is directed to methods for retrieving and using at least one lymphocyte. Additionally, cell receptor sequences identified with this strategy could be used for antibody development, TCR discovery, or appropriate therapeutics development or evaluation.
    Type: Grant
    Filed: August 4, 2016
    Date of Patent: March 5, 2019
    Assignee: RareCyte, Inc.
    Inventor: Lance U'Ren
  • Patent number: 10215169
    Abstract: This disclosure is directed to an apparatus, system and method for introducing a liquid into a vessel. A fluid layering system includes a pump connected to a line connected to a connector, such that the connector provides an air-tight fit with the vessel.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: February 26, 2019
    Assignee: RareCyte, Inc.
    Inventors: Steve Quarre, Edward Shafer, Lance U'Ren, Jennifer Chow
  • Patent number: 10101247
    Abstract: This disclosure is directed to a method and an attachment solution for adhering a cytological or histological sample, such as buffy coat, to a substrate, such as a microscope slide. The attachment solution includes an attachment base, an anti-coagulant, and a nonsteroidal anti-inflammatory drug. The attachment base may be an alcohol, an acid, an oxidizer, an organohalogen, a ketone, or any combination thereof. Once a sample is obtained, the sample may be re-suspended in the attachment solution or the attachment solution may be added to the sample. The sample may then be dispensed onto an analysis platform as one or more droplets and cured.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: October 16, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Ronald Seubert, Steve Quarre
  • Patent number: 10101248
    Abstract: This disclosure is directed to a method and an attachment solution for adhering a cytological or histological sample, such as buffy coat, to a substrate, such as a microscope slide. The attachment solution includes an attachment base, an anti-coagulant, and a nonsteroidal anti-inflammatory drug. The attachment base may be an alcohol, an acid, an oxidizer, an organohalogen, a ketone, or any combination thereof. Once a sample is obtained, the sample may be re-suspended in the attachment solution or the attachment solution may be added to the sample. The sample may then be dispensed onto an analysis platform as one or more droplets and cured.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: October 16, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Ronald Seubert
  • Patent number: 10088392
    Abstract: This disclosure is directed to a device and a system for aspirating and dispensing a target analyte, target material, or fluid. A picker may aspirate and dispense the desired material by introducing a pressure gradient. The picker may include a hydraulic fluid to hydraulically couple at least two components, such as a moveable pump component and a cannula.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: October 2, 2018
    Assignee: RareCyte, Inc.
    Inventors: Joshua Nordberg, Steve Quarre, Ronald Seubert
  • Patent number: 10072927
    Abstract: This disclosure is directed to a system and method for detecting a surface of a substrate within a scanner.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: September 11, 2018
    Assignee: RareCyte, Inc.
    Inventors: Paulina Varshavskaya, Edward Shafer, Steve Quarre, Ronald C. Seubert
  • Patent number: 10054524
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. An enrichment agent may be added to a vessel that contains the sample for positive selection, or, in other words, to select or aid in selecting the target material from amongst the remainder of the sample. The enrichment agent may be, for example, immunomagnetic beads, buoyant beads, high-density beads, chemicals to change the density of the target material, or the like.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: August 21, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Publication number: 20180195935
    Abstract: This disclosure is directed to a device and a system for aspirating and dispensing a target analyte, target material, or fluid. A picker may aspirate and dispense the desired material by introducing a pressure gradient. The picker may include a hydraulic fluid to hydraulically couple at least two components, such as a moveable pump component and a cannula.
    Type: Application
    Filed: April 11, 2017
    Publication date: July 12, 2018
    Applicant: RareCyte, Inc.
    Inventors: Joshua Nordberg, Steve Quarre, Ronald Seubert
  • Patent number: 10018538
    Abstract: This disclosure is directed to an apparatus and method for spreading a fluid across a substrate. A spreader for spreading a fluid across a substrate includes a wiper and a frame. The wiper and the frame may mate to permit translation of the wiper across, and with respect to, the frame. The wiper spreads the fluid across the substrate and the frame supports the wiper and the substrate. The frame may also include a ramp to cause a portion of the wiper to lift away from the substrate.
    Type: Grant
    Filed: November 22, 2015
    Date of Patent: July 10, 2018
    Assignee: RareCyte, Inc.
    Inventors: Joshua Nordberg, Daniel Campton, Steve Quarre, David Stewart
  • Patent number: 9956555
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving target material from a suspension. A system includes a processing vessel, a displacement fluid, and a tube. The tube includes a funnel, a cannula, and a cavity. The cannula allows for fluid communication between the funnel and the cavity, such that the processing vessel is inserted into the cavity, and the cannula extends into the processing vessel.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: May 1, 2018
    Assignee: RareCyte, Inc.
    Inventors: Lance U'Ren, Ronald Seubert
  • Patent number: 9945839
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a displacement fluid, a collector, and a primary vessel. In another implementation, the system includes a processing vessel, a displacement fluid, a collector, and a primary vessel.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: April 17, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert
  • Publication number: 20180030979
    Abstract: This disclosure is directed to an apparatus, system and method for introducing a liquid into a vessel. A fluid layering system includes a pump connected to a line connected to a connector, such that the connector provides an air-tight fit with the vessel.
    Type: Application
    Filed: May 15, 2017
    Publication date: February 1, 2018
    Applicant: RareCyte, Inc.
    Inventors: Steve Quarre, Edward Shafer, Lance U'Ren, Jennifer Chow
  • Publication number: 20180003940
    Abstract: This disclosure is directed to an apparatus for securely holding a substrate, such as a microscope slide. A holder includes a frame including at least three walls, such as a base, a first arm, and a second arm. Each wall includes a platform or a portion of a platform to support the substrate. The first arm includes at least one securing block and a second arm opposite the first arm includes a secure bar with a securing block. The securing blocks include a ramp to guide the substrate off of the platforms and a stopper to set a maximum lift distance and to constrain the substrate.
    Type: Application
    Filed: September 19, 2017
    Publication date: January 4, 2018
    Applicant: RareCyte. Inc.
    Inventors: Steve Quarre, David Stewart
  • Publication number: 20180003939
    Abstract: This disclosure is directed to an apparatus for securely holding a substrate, such as a microscope slide. A holder includes a frame including at least three walls, such as a base, a first arm, and a second arm. Each wall includes a platform or a portion of a platform to support the substrate. The first arm includes at least one securing block and a second arm opposite the first arm includes a secure bar with a securing block. The securing blocks include a ramp to guide the substrate off of the platforms and a stopper to set a maximum lift distance and to constrain the substrate.
    Type: Application
    Filed: September 19, 2017
    Publication date: January 4, 2018
    Applicant: RareCyte, Inc.
    Inventors: Steve Quarre, David Stewart
  • Patent number: 9857580
    Abstract: This disclosure is directed to an apparatus for securely holding a substrate, such as a microscope slide. A holder includes a frame including at least three walls, such as a base, a first arm, and a second arm. Each wall includes a platform or a portion of a platform to support the substrate. The first arm includes at least one securing block and a second arm opposite the first arm includes a secure bar with a securing block. The securing blocks include a ramp to guide the substrate off of the platforms and a stopper to set a maximum lift distance and to constrain the substrate.
    Type: Grant
    Filed: May 21, 2015
    Date of Patent: January 2, 2018
    Assignee: RareCyte, Inc.
    Inventors: Steve Quarre, David Stewart
  • Publication number: 20170363850
    Abstract: This disclosure is directed to system for transferring a substrate, such as a microscope slide, and holding the substrate within at least one device. The system includes a holder for holding the substrate and a gripper for transferring the substrate, such as between a cassette or stack and the holder. A method is also discussed herein.
    Type: Application
    Filed: May 22, 2017
    Publication date: December 21, 2017
    Applicant: RareCyte, Inc.
    Inventors: Steve Quarre, Edward Shafer, David Stewart, Joel Smith