Abstract: Atmospheric pressure ion guides are provided. The atmospheric pressure ion guides can include a multi-ring electrode structure connecting a larger opening to a smaller opening and having a series of ring electrodes with decreasing diameter and voltage going from the larger opening to the smaller opening. The electrodes can be made from stainless steel or other suitable conductive material. The multi-ring electrode structure can be contained in a housing, such as a housing made from polyetheretherketone or other suitable thermosetting polymer. The atmospheric pressure ion guide can focus ions from an ion source for use with ion detection devices such as an ion mobility spectrometer or a mass spectrometer. Methods of using the atmospheric pressure ion guides are provided, for example to focus a plurality of ions to be injected into an ion detection device. The atmospheric pressure ion guides can increase the signal intensity of the ion detection device.

Abstract: Compounds described herein are mithramycin (MTM) oxide (OX) derivatives and MTM Hydrazine (HY) derivatives. These compounds are useful for treatment of cancers and neuro-diseases.

Abstract: Methods of detecting and categorizing an action in an untrimmed video segment regardless of the scale of the action and the close proximity of other actions. The methods improve upon the prior art which either require trimmed video segments including only a single activity depicted therein, or untrimmed video segments including relatively few actions, persons, or objects of interest, thereby directing the classification. Instead, the methods utilize a plurality of tubelets used to represent discreet actions, persons, and objects of interest within the comprehensive untrimmed video segment. The tubelets are localized to correct for pixel-level foreground-background biases, which are then turned into short spatio-temporal action tubelets that are passed to a classification network to obtain multi-label predictions. After classification, the tubelets are be linked together to obtain the final detections with varying lengths, and the method merges the short action tubelets into final action detections.

Abstract: System and method of manufacturing high-strength bonded metal sheets for a battery cell are provided. The method comprises providing a stackup comprising a first metal sheet and a second metal sheet. The first and second metal sheets are separated by a first coating layer. The first coating layer comprises nickel-phosphide. The first metal sheet includes a first material of a first melting point and the second metal sheet includes a second material of a second melting point. The first coating layer including a third material of a third melting point. The method further comprises heating the stackup to allow crystallization of nickel in the first coating layer and remove the residual nickel-phosphide defining an enhanced coating layer. The enhanced coating layer comprises crystallized nickel for high-strength solid state bonding of the first and second metal sheets to the enhanced coating layer.

Abstract: Described herein is a wireless charging system including switched capacitor (SC) rectifiers with output regulation. The load for the receiver on mobile devices using wireless charging is a battery. Regulation is needed for battery charging applications, e.g. constant voltage charging, constant current charging, and pulsed charging. For this purpose, the wireless power transfer (WPT) receiver can possess some “intelligence” to monitor the output voltage/current, adjust the behavior of the electronic circuitries and achieve a closed-loop control. Because a multilevel switched-capacitor (MSC) rectifier has output control ability, this can allow the MSC rectifier to directly charge the battery without an additional DC/DC charger on-board the device.

Abstract: Described herein are diagnostic and control fusion protein reagents and methods for use thereof in simple rapid and inexpensive hemagglutinin assays for the detection of subject antibodies directed to the SARS-CoV-2 virus.

Abstract: Embodiments of the present disclosure provide for methods of detecting, sensors (e.g., chromogenic sensor), kits, compositions, and the like that related to or use tunable macroporous polymer. In an aspect, tunable macroporous materials as described herein can be used to determine the presence of a certain type(s) and quantity of liquid in a liquid mixture.

Abstract: A transformer emulator includes a DC bus, a first power electronics converter circuit having a DC port coupled to the DC bus, a second power electronics converter circuit having a DC port coupled to the DC bus, and a third power electronics converter circuit having DC port coupled to the DC bus. The transformer emulator further includes a control circuit configured to control the first, second and third power electronics converter circuits to emulate a transformer having a first port corresponding to an AC port of the first power electronics converter circuit and a second port corresponding to an AC port of the second power electronics converter circuit. The control circuit is configured to control the first and second power electronics converter circuits to emulate a voltage transformation of the transformer and to control the third power electronics converter circuit to emulate a loss of the transformer.

Abstract: The present disclosure relates to a novel vapor compression refrigeration system, and the methods of making and using the vapor compression refrigeration system.

Abstract: An economical, efficient, and effective formation of a high resolution pattern of conductive material on a variety of films by polymer casting. This allows, for example, quite small-scale patterns with sufficient resolution for such things as effective microelectronics without complex systems or steps and with substantial control over the characteristics of the film. A final end product that includes that high resolution functional pattern on any of a variety of substrates, including flexible, stretchable, porous, biodegradable, and/or biocompatible. This allows, for example, highly beneficial options in design of high resolution conductive patterns for a wide variety of applications.

Abstract: Methods and catalysts for oxidizing ammonia to nitrogen are described. Specifically, diruthenium complexes that spontaneously catalyze this reaction are disclosed. Accordingly, the disclosed methods and catalysts can be used in various electrochemical cell-based energy storage and energy production applications that could form the basis for a potential nitrogen economy.

Abstract: A tissue construct is provided that comprises a pancreas derived microvessel fragment and a pancreatic islet cell. The pancreas derived microvessel fragment and the pancreatic islet cell can be incorporated into a biocompatible medium. Tissue constructs can be comprised of other cells, such as stem cells, combined with the pancreas derived microvascular fragment. Methods for isolating microvessel fragments from a pancreas are also provided and include enzymatic digestion of pancreatic tissue and separation of microvessel fragments from endocrine and exocrine tissue. Methods for treating diabetes are further provided and include administration of the tissue constructs.

Abstract: Methods of making metal halide perovskites, including methods of making micro crystals of metal halide perovskites. The metal halide perovskites, including the micro crystals, may have a 0D structure. The metal halide perovskites may be a light emitting material.

Abstract: Methods for generating aortic heart valve leaflets are disclosed wherein the aortic sinus surfaces (the inner surfaces of the sinuses of Valsalva) are used as a template to generate geometric representations of replacement aortic heart valve leaflets. As such, sinus-matched replacement leaflets can be sized and shaped according to the patient-specific geometry of the aortic root. Patient-specific aortic valve assemblies based on aortic root and sinus geometry are also described. Methods for estimating the coaptation area of a sinus-matched valve and assessing whether the valve is functionally competent for implantation are described.

Abstract: This invention relates to tracking of hand-held devices and vehicles with respect to each other, in circumstances where there are two or more users or existent objects interacting in the same share space (co-location). It extends conventional global and body-relative approaches to “cooperatively” estimate the relative poses between all useful combinations of user-worn tracked devices such as HMDs and hand-held controllers worn (or held) by multiple users. Additionally, the invention provides for tracking of vehicles such as cars and unmanned aerial vehicles.

Abstract: Disclosed is a built-in type electric driving system of a machine tool. The system is capable of directly connecting a motor, which drives a spindle in a lathe which processes a workpiece, to an outer surface of the spindle without using a belt to rotate the spindle, and is capable of selectively transferring the power of the motor to a rotation system including a drawbar and a spindle for driving a chuck using a clutch device.

Abstract: The invention pertains to a PPA from a microorganism belonging to the family Halobacteriaceae (HPPA), for example, a PPA from Haloferax volcanii. The HPPA provided by the invention is soluble, thermostable and active at high concentrations of salt and/or organic solvent. An embodiment of the invention provides a method of increasing the rate of a reaction by adding an HPPA to the reaction mixture, wherein the reaction produces PPi, for example, an enzymatic reaction, and wherein the reaction is carried out at moderately high temperature and/or low water activity. Further embodiments of the invention provide an assay to detect the PPi released during a reaction which produces PPi by adding an HPPA to convert the PPi in to Pi and measuring the resultant Pi. The invention further pertains to an assay to monitor a reaction which produces PPi in the presence or the absence of an HPPA.

Abstract: A method of identifying an object of interest can comprise obtaining first samples of an intensity distribution of one or more object of interest, obtaining second samples of an intensity distribution of confounder objects, transforming the first and second samples into an appropriate first space, performing dimension reduction on the transformed first and second samples, whereby the dimension reduction of the transformed first and second samples generates an object detector, transforming one or more of the digital images into the first space, performing dimension reduction on the transformed digital images, whereby the dimension reduction of the transformed digital images generates one or more reduced images, classifying one or more pixels of the one or more reduced images based on a comparison with the object detector, and identifying one or more objects of interest from the classified pixels.

Abstract: A system for propelling a magnetic robotic device through a human comprises a magnetic actuator device operable to generate a rotating magnetic field, and a magnetic robotic device comprising a compliant body and at least two permanent magnets supported by and spatially separated about the compliant body. A non-magnetic region can also be oriented between the at least two permanent magnets. The at least two permanent magnets can be alternating or non-alternating in polarity with each other. In response to application of the rotating magnetic field generated by the magnetic actuator device and that is situated proximate the magnetic robotic device, the rotating magnetic field effectuates undulatory locomotion of the magnetic robotic device to propel the magnetic robotic device through a human, such as through a natural lumen. Further, the magnetic robotic device can optionally be supported by a catheter or endoscope to assist with propelling a distal end through a human.

Abstract: The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.