Abstract: In accordance with some embodiments, systems, methods, and media for asynchronous single photon depth imaging with improved precision in ambient light conditions are provided. In some embodiments, the system comprises: a light source; a detector configured to detect arrival of individual photons, and enter a dead time after a detection; a processor programmed to: cause the light source to emit pulses toward a scene point at the beginning of light source cycles each corresponding to B time bins; cause the detector to enter an acquisition window at a first time bin position; cause the detector to enter another acquisition window at a shifted time bin position; record photon arrival times; associate each photon arrival time with a time bin; and estimate a depth of the scene point based on a number of photon detection events at each time bin, and a denominator corresponding to each time bin.

Abstract: Various examples are provided for wireless power transfer to implants. In one example, a system includes a radio frequency (RF) power source and a transmitter (TX) array comprising an excitation coil and resonant coils distributed about the excitation coil. The TX array can transfer power from the RF power source to a biomedical implant inserted below a skin surface of a subject when the TX array is positioned on the skin surface adjacent to the biomedical implant. A receiver (RX) coil of the biomedical implant can inductively couple with the TX array for the power. The resonant coils can allow power transfer when the RX coil is not aligned with the excitation coil.

Abstract: The present disclosure generally relates to methods of treating hemolytic diseases such as sickle cell anemia using kinase inhibitors, for example, compounds that inhibit the spleen tyrosine kinase (SYK). In some embodiments a method is presented to prevent thrombosis in blood vessels of patients with a hemolytic disease comprising the step of: administrating to a patient having at least one hemolytic disease a therapeutically effective amount of at least one SYK inhibitor. In some embodiments the method includes repeatedly administering the SYK kinase inhibitor to a patient.

Abstract: A method and system for localizing a plurality of stationary devices, such as Internet of Things (IoT devices), arranged in an environment is disclosed. A mobile device is configured to survey an environment to generate a three-dimensional map of the environment using simultaneous localization and mapping (SLAM) techniques. The mobile device and the stationary devices are equipped with wireless transceivers, such as Ultra-wideband radios, for measuring distances between the devices using wireless ranging techniques. Based on the measured distances, the mobile device is configured to determine locations of the stationary devices in a reference frame of the three-dimensional map. In some embodiments, the determined locations can be used to enable a variety of spatially aware augmented reality features and interactions between the mobile device and the stationary device.

Abstract: The invention provides a method for treating one or more complications of diabetes in a mammal. The method comprises administering to a mammal in need thereof an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about twenty amino acids; a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3 pm is the largest number that is less than or equal to r+1; and a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 2a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1.

Abstract: Substituted benzo[f]imidazo[1,5-?][1,4]diazepines of formula (I?) target alpha-4 and alpha-5 GABAA receptors for use in the treatment of airway hyperresponsiveness and inflammation in asthma. Compounds selectively partition to the peripheral compartment and have reduced CNS effects.

Abstract: The present disclosure relates to wheat plants having grain with high ?-glucan content, methods for constructing said wheat plants, grain therefrom and uses thereof. Wheat lines homozygous for the HvCslF6 gene from barley having five times the fiber content and an increased ?-glucan content of TA5790, TA5792, and TA5795 are disclosed.

Abstract: A method of making coated avian egg yolk cores includes providing dried avian egg yolk cores having a diameter of 100 to 1500 micrometers, applying avian egg albumen to the dried avian egg yolk cores to provide the coated avian egg yolk cores, and optionally drying the coated avian egg yolk cores, wherein the ratio of dry avian egg albumen to dried avian egg yolk in the coated avian egg yolk cores is 1:10 to 10:1. Also included are the coated avian egg yolk cores, food and feed additives containing the coated avian egg yolk cores and food and feed compositions containing the coated avian egg yolk cores.

Abstract: Systems and methods for accurately measuring changes in biomarker sensitive hydrogel volume and shape due to exposure to various biomarkers include a system for identifying one or more dimensional changes in a biomarker sensitive hydrogel positioned within an in vivo environment. The system includes a biomarker sensitive hydrogel positioned within an in vivo environment and configured to dimensionally change in response to interaction with predefined biomarkers. The system additionally includes an ultrasound transducer for locating and identifying one or more characteristics of the biomarker sensitive hydrogel and a computer system in electrical communication with the ultrasound transducer. The computer system is configured to receive characteristics of the biomarker sensitive hydrogel from the ultrasound transducer and determine dimensional changes of the biomarker sensitive hydrogel based on the received characteristics.

Abstract: A solar vapor generator system and method are provided. In some embodiments, the system has near perfect energy conversion efficiency in the process of solar vapor generation below room temperature. Remarkably, when the operation temperature of the system is below that of the surroundings, the total vapor generation will be higher than the upper limit that can be produced by the input solar energy.

Abstract: Provided herein are nucleic acids, recombinant adeno-associated viral particles, compositions and methods related to treating Friedreich's ataxia. In some examples, the nucleic acids, recombinant adeno-associated viral particles, compositions and methods involve us of a FXN coding sequence, a truncated FXN 3? UTR, and a prompter.

Abstract: A monitoring system or tracking system may include an input port and a controller in communication with the input port. The input port may receive video from one or more image capturing devices. The image capturing device is optionally part of the monitoring system and in some cases includes at least part of the controller. The controller may be configured to receive video via the input port and identify a subject within frames of the video relative to a background within the frames. Further, the controller may be configured to identify dimensions, posture, hand location, feet location, twisting position/angle, and/or other parameters of the identified subject in frames of the video and determine when the subject is performing a task. Based on the dimensions and/or other parameters identified or extracted from the video during the predetermined task, the controller may output via the output port assessment information.

Abstract: Peptides and conjugates are described herein, including peptides having antimicrobial and/or anticancer properties, as are compositions, articles, and kits comprising such peptides and conjugates, and methods for using the peptides and conjugates.

Abstract: A mapping method for identifying density which includes determining at least one geographical boundary about a geographical location of interest, the at least one geographical boundary is free of any self-intersections, dividing the at least one geographical boundary into a plurality of regions of interests, each region of interest is defined by a start point and an end point on the at least one geographical boundary, wherein the end point associated with one region of interest coincides with a start point of a neighboring region of interest wherein the region of interest falls within the at least one geographical boundary, for each of the plurality of regions of interest, calculating at least one parameter of interest within the region of interest, and graphically presenting a segment between the start point and the end point on the at least one geographical boundary with a line thickness proportional to the calculation results.

Abstract: The nonlinearity of power amplifiers (PAs) has been a severe constraint in performance of modern wireless transceivers. This problem is even more challenging for the fifth generation (5G) cellular system since 5G signals have extremely high peak to average power ratio. Non-linear equalizers that exploit both deep neural networks (DNNs) and Volterra series models are provided to mitigate PA nonlinear distortions. The DNN equalizer architecture consists of multiple convolutional layers. The input features are designed according to the Volterra series model of nonlinear PAs. This enables the DNN equalizer to effectively mitigate nonlinear PA distortions while avoiding over-fitting under limited training data. The non-linear equalizers demonstrate superior performance over conventional nonlinear equalization approaches.

Abstract: Herein reported are new tricyclic cytidine compounds, such as 8-diethylamino-tC (8-DEA-tC), that respond to DNA and/or RNA duplex formation with up to a 20-fold increase in fluorescent quantum yield as compared with the free nucleoside, depending on neighboring bases. This turn-on response to duplex formation is by far the greatest of any reported nucleoside analogue that can participate in Watson-Crick base pairing. Measurements of the quantum yield of 8-DEA-tC mispaired with adenosine and, separately, opposite an abasic site show that there is almost no fluorescence increase without the formation of correct Watson-Crick hydrogen bonds. Kinetic isotope effects from the use of deuterated buffer show that the duplex protects 8-DEA-tC against quenching by excited state proton transfer. DFT calculations provide a rationale for the observed photophysical properties that is dependent on duplex integrity and the electronic structure of the analogue.

Abstract: Methods and compositions relating to TIC10 are described according to aspects of the present invention. The compositions and methods have utility in treating disease, particularly cancer in a subject in need thereof, including a human subject as well as subjects of other species. The compositions have utility in treating brain cancer in a subject in need thereof.

Abstract: Disclosed herein a unique cell line system to generate a novel bovine adenovirus vector that provides more gene insertion capabilities and better immunogenicity for inserted antigens. The unique cell line is used for generating and growing of the new adenovirus vectors for gene delivery or recombinant vaccine production.

Abstract: An exemplary system, method and computer-accessible medium for harmonizing neuromelanin (NM) data using combat directly on a NM database or using combat generated coefficients to harmonize future data can include, for example, receiving imaging information of a brain of the patient(s), from one MRI scanner, receiving imaging information of a brain of the patient(s), from a second MRI scanner and using combat to harmonize the data between scanners against a reference dataset. The Neuromelanin (NM) concentration of the patient(s) can then be determined based on the harmonized data. The NM concentration can be determined using a voxel-wise analysis procedure. The voxel-wise analysis procedure can be used to determine a topographical pattern(s) within a substantia nigra (SN) of the brain of the patient(s).

Abstract: A new and distinct cultivar of Hibiscus plant named ‘RutHib4’ is characterized by a combination of compact, dense growth form, that is smaller than either parent, bright red flowers with a darker red eyespot, better adaptation to southern climates, and improved disease resistance to aerial phytophthora, fungal and bacterial leaf spots.