Abstract: A fibrocartilage suturing device is provided to solve the problem where the conventional procedure of the surgery is inconvenient. The fibrocartilage suturing device includes a tube assembly, a tubular member, and an anchor. The tube assembly extends through the tube assembly and includes an insertion section. The movement member is coupled with the tube assembly and includes a thrust rod extending through the tubular member. The anchor is located at one end of the thrust rod and includes a body and at least two wings connected to the body is able to be folded and unfolded relative to the body. The body of the anchor is connected to an end of a thread. Another end of the thread is connected to the tubular member.
Type:
Grant
Filed:
September 12, 2019
Date of Patent:
June 28, 2022
Assignee:
METAL INDUSTRIES RESEARCH & DEVELOPMENT CENTRE
Abstract: A population of early-stage burst-forming unit-eryhtoid (BFU-E) cells characterized by low expression of the Type III Transforming Growth Factor ? Receptor (TGFRPIII) and uses thereof for producing red blood cells in vitro, genotoxicity analysis of chemicals, drug sensitivity assessment, and drug development. Also described herein are methods for producing the population of early-stage BFU-E cells and methods for producing red blood cells.
Type:
Grant
Filed:
March 3, 2017
Date of Patent:
June 28, 2022
Assignee:
Whitehead Institute for Biomedical Research
Inventors:
Harvey Lodish, Xiaofei Gao, Hsiang-Ying Lee
Abstract: The present invention provides novel liposomes comprising Gd.DOTA.DSA (gadolinium (III) 2-{4,7-bis-carboxymethyl-10-[(N,N-distearylamidomethyl-N?-amido-methyl]-1,4,7,10- =tetra-azacyclododec-1-yl}-acetic acid), characterised in that the liposome further comprises a neutral, fully saturated phospholipid component (e.g. DSPC (1,2-distearoyl-sn-glycero-3-phospocholine]), which are of particular use in the preparation of magnetic resonance contrast agents for enhancing a magnetic resonance image of tumours in a mammal.
Type:
Grant
Filed:
March 20, 2017
Date of Patent:
June 28, 2022
Assignees:
UNITED KINGDOM RESEARCH AND INNOVATION, IMPERIAL INNOVATIONS LIMITED
Inventors:
Nazila Kamaly, Tammy Louise Kalber, Gavin David Kenny, Maya Thanou, Andrew David Miller, Jimmy David Bell
Abstract: An operation method and an operation device of a motor driver for driving a motor are provided. The operation method includes: establishing a hysteresis control method; and adjusting a switch frequency of a power module for operating the motor by using the hysteresis control method according to a change of rotation speed of the motor and a current switch frequency.
Type:
Grant
Filed:
December 29, 2020
Date of Patent:
June 28, 2022
Assignee:
INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
Abstract: The present invention relates to a vinylarene deriv. which modulates or inhibits the enzymic activity of indoleamine 2,3-dioxygenase 1 (IDO-1), and the use thereof, and further relates to a vinylarene deriv. and the use thereof. The vinylarene deriv. and its stereoisomer, cis- or trans-isomer, or tautomer thereof and pharmaceutically acceptable salt thereof, has an IDO-1 enzyme inhibitory activity, and is expected to provide brand new therapeutic methods and schemes for related diseases caused by IDO enzymes.
Type:
Grant
Filed:
May 31, 2018
Date of Patent:
June 28, 2022
Assignee:
SHENYANG RESEARCH INSTITUTE OF CHEMICAL INDUSTRY CO., LTD.
Abstract: A method for transmitting and receiving slot setting information in a communication system is disclosed. An operating method of a UE comprises the steps of: receiving, from a base station, a first upper layer message including SFI for indicating a format of a slot; receiving, from the base station, DCI or a second upper layer message for indicating a use of a flexible symbol belonging to the slot set by the SFI; and determining the flexible symbol belonging to the slot as a DL symbol or a UL symbol on the basis of the second upper layer message or the DCI. Therefore, a performance of a communication system can be improved.
Type:
Grant
Filed:
August 3, 2018
Date of Patent:
June 28, 2022
Assignee:
Electronics and Telecommunications Research Institute
Inventors:
Hoi Yoon Jung, Sung Ik Park, Heung Mook Kim, Nam Ho Hur
Abstract: Provided is a method for determining convergence in full wavefield inversion (FWI) of 4D seismic (time-lapse seismic: 3D seismic surveys acquired at different times with the first survey termed as the baseline and subsequent surveys termed as monitors). FWI applied to field seismic data includes iteratively solving for subsurface property models and model difference between monitor and baseline. Iteration occurs until the model difference is sufficiently converged. Rather than determining convergence by examining an entire subsurface region of the models and/or the model difference, subparts of the subsurface region models and/or the model difference are examined in order to determine convergence. For example, different regions behave differently, include the target reservoir region (where hydrocarbon is present) and the background region that is outside the target reservoir region.
Type:
Grant
Filed:
September 29, 2020
Date of Patent:
June 28, 2022
Assignee:
ExxonMobil Upstream Research Company
Inventors:
Ganglin Chen, Musa Maharramov, David H. Johnston, Partha Routh
Abstract: A lubricant composition comprising: (i) silver or gold nanoparticles, each of which is encapsulated by a layer of alkylthiol or alkylamine molecules; (ii) palladium or platinum nanoparticles, each of which is encapsulated by a layer of alkylthiol or alkylamine molecules; and (iii) a fluid in which components (i) and (ii) are present. Further described are methods for applying the lubricant composition onto a mechanical device for which lubrication is beneficial, with resulting improvement in friction and wear reduction and/or corrosion inhibition.
Type:
Grant
Filed:
May 15, 2019
Date of Patent:
June 28, 2022
Assignees:
UT-Battelle, LLC, University of Tennessee Research Foundation
Inventors:
Chanaka Kapila Kumara Ihala Gamaralalage, Jun Qu
Abstract: An operation method of a UE in a communication system includes receiving, from a base station, a security mode command message including information requesting reporting of capability information and security configuration information; identifying the security configuration information included in the security mode command message; and transmitting, to the base station, a security mode complete message including the capability information requested by the security mode command message.
Type:
Grant
Filed:
November 13, 2019
Date of Patent:
June 28, 2022
Assignee:
ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
Abstract: The present disclosure relates to bioactive self-assembling peptides, nanofibers and hydrogels for activating human mast cells. The peptides, nanofibers and hydrogels comprise a self-assembling peptide that mediates self-assembly linked to a MrgX2 agonist peptide; for example, (RADA)4 linked to proadrenomedullin-12 (PAMP-12).
Type:
Grant
Filed:
May 25, 2018
Date of Patent:
June 28, 2022
Assignees:
The Governors of the University of Alberta, National Research Council of Canada
Inventors:
Larry D. Unsworth, Lei Lu, Marianna Kulka
Abstract: Described herein are RSV polynucleotide sequences that make use of multiple codons that are containing silent nucleotide substitutions engineered in multiple locations in the genome, wherein the substitutions introduce a numerous synonymous codons into the genome. Due to the large number of defects involved, the attenuated viruses disclosed herein provide a means of producing attenuated, live vaccines against RSV.
Type:
Grant
Filed:
March 16, 2018
Date of Patent:
June 28, 2022
Assignees:
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES, THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Inventors:
Peter L. Collins, Cyril Le Nouën, Linda G. Brock, Ursula J. Buchholz, Joshua Marc DiNapoli, Steffen Mueller, Eckard Wimmer
Abstract: A medical device of a medical system is configured for communicating with an external programmer over a wireless communications link. The medical device comprises a wireless communications module configured for receiving a first unencrypted version of a random number and a first encrypted version of the random number from the external programmer over the wireless communications link. The medical device further comprises control circuitry configured for performing an authentication procedure on the external programmer based on the first unencrypted version of the random number and the first encrypted version of the random number, and preventing the external programmer from commanding the medical device to perform an action unless the authentication procedure is successful.
Type:
Grant
Filed:
May 8, 2020
Date of Patent:
June 28, 2022
Assignee:
THE ALFRED E. MANN FOUNDATION FOR SCIENTIFIC RESEARCH
Inventors:
Saul Rodriguez, Dianna (Dan) Han, Emil Istoc
Abstract: The present invention provides novel substituted benzimidazole derivatives of formula (I) used as DAAO inhibitors and for treatment and/or prevention of neurological disorders.
Type:
Grant
Filed:
September 14, 2017
Date of Patent:
June 28, 2022
Assignees:
NATIONAL TAIWAN UNIVERSITY, NATIONAL YANG MING CHIAO TUNG UNIVERSITY, NATIONAL HEALTH RESEARCH INSTITUTES
Abstract: Photoreceptor scaffolds and scaffold systems including the photoreceptor scaffolds are described herein. The scaffolds and scaffold systems can be used for transplantation of organized photoreceptor tissue, with or without RPE, which may improve grafted cell survival, integration, and functional visual rescue. Particularly, the photoreceptor scaffold is structured from a biocompatible film, patterned with an array of unique through-holes having a curvilinear cell receiver and at least one cell guide channel.
Type:
Grant
Filed:
February 5, 2016
Date of Patent:
June 28, 2022
Assignee:
Wisconsin Alumni Research Foundation
Inventors:
Zhenqiang Ma, Yei Hwan Jung, Michael Phillips, David Gamm, Shaoqin Gong
Abstract: The present invention concerns the use of an alpha-glucosidase glycoprotein processing inhibitor for the treatment or prevention of human coronavirus infections, such as SARS-CoV-2 or SARS-CoV-2 variant infections. Aspects of the invention include methods for treating or preventing coronavirus infection, or a symptom thereof, by administering an alpha-glucosidase glycoprotein processing inhibitor, such as castanospermine, or a pharmaceutically acceptable salt, derivative, or prodrug thereof, to a human subject; methods for inhibiting human coronavirus infection in a human cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits for treating or preventing human coronavirus infection.
Type:
Grant
Filed:
February 19, 2021
Date of Patent:
June 28, 2022
Assignee:
FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
Inventors:
Eric Holmes, Gary Ostrander, Geoffrey Stuart Dow
Abstract: A method for reporting channel state information (CSI) by means of a terminal in a wireless communication system, according to one embodiment of the present invention, comprises the steps of: receiving a channel state information reference signal (CSI-RS) from a base station, wherein the CSI-RS is related to at least one panel of an antenna array of the base station; generating CSI on the basis of the CSI-RS and a codebook according to a specific shape of the at least one panel; and reporting the CSI to the base station.
Type:
Grant
Filed:
November 19, 2019
Date of Patent:
June 28, 2022
Assignees:
LG Electronics Inc., Sogang University Research Foundation
Inventors:
Jonghyun Park, Jiyeong Yang, Wonjin Sung, Haewook Park
Abstract: Coating compositions, coated articles including the coating compositions, and methods of making the coating compositions and coated articles are provided. In some aspects, the coating compositions are applied to a substrate having nitric oxide-releasing properties. The coating compositions can include copolymers having crosslinking agents that can be activated with mild UV light (about 345 nm to 365 nm) to avoid damaging the substrate while creating strong covalent bonds to the substrate. The copolymers can include hydrophilic repeat units, and in particular zwitterionic repeat units such as repeat units containing phosphorylcholine groups. In some aspects, the coating compositions are applied to a surface of a polymer substrate, wherein the polymer substrate had nitric oxide releasing properties. The coating compositions and the coated articles can have antifouling, antithrombotic, and/or antibacterial properties.
Type:
Grant
Filed:
October 19, 2018
Date of Patent:
June 28, 2022
Assignee:
University of Georgia Research Foundation, Inc.
Inventors:
Jason J. Locklin, Qiaohong Liu, Priyadarshini Singha, Hitesh Handa, Jitendra Pant, Marcus J. Goudie, Sean P. Hopkins
Abstract: A carbon dioxide reducing photocatalyst is provided. The carbon dioxide reducing photocatalyst comprises: an electron receptor comprising a metal oxide; a polymer concentrator deposited on the electron receptor; and a metal catalyst deposited on the electron receptor, wherein electrons move from the polymer concentrator to the metal catalyst through the conduction band of the electron receptor if the polymer concentrator absorbs light.
Type:
Application
Filed:
March 4, 2022
Publication date:
June 23, 2022
Applicant:
Korea University Research and Business Foundation, Sejong Campus
Abstract: A new distinct variety of grapevine named ‘ARDFORTYTHREE’ abundantly forms attractive meaty seedless berries with a red skin coloration, medium density and large clusters which display a natural flavor, the fruit commonly is ready for harvesting during August in San Joaquin Valley of Central California, U.S.A, and displays good eating qualities as a table grape as the fruit firmness renders the fruit well amenable for handling, shipping, and storage.
Type:
Grant
Filed:
January 31, 2022
Date of Patent:
June 28, 2022
Assignee:
Agricultural Research and Development Limited Liability Company