Patents Assigned to Research
  • Patent number: 10264962
    Abstract: A pupillometer system includes a computer, a camera, and a testing compartment provided in the form of a substantially hemispheric bowl, where the substantially hemispheric bowl includes a plurality of chromatic beam emitters arranged about a visual field forming a plurality of visual field testing points. The plurality of chromatic beam emitters generate a first chromatic stimulus that stimulates a first anatomical structure of an eye and a second chromatic stimulus that stimulates a second anatomical structure of the eye where the first anatomical structure is different than the second anatomical structure. The camera records a pupil response of one or more eyes. The computer generates quantitative pupillary light reflex (PLR) measurements of the PLR in response to the stimuli, determines at least one PLR response ratio, and determines a state of health of the one or more eyes utilizing the at least one PLR response ratio.
    Type: Grant
    Filed: May 4, 2018
    Date of Patent: April 23, 2019
    Assignee: Tel Hashomer Medical Research Infrastructure and Services, Ltd.
    Inventors: Ygal Rotenstreich, Mordecai Rosner
  • Patent number: 10266607
    Abstract: The present invention relates to an antibody that binds specifically to a tissue factor pathway inhibitor (TFPI), a nucleic acid encoding the antibody, a vector comprising the nucleic acid, a host cell transformed with the vector, a method for producing the antibody, and a pharmaceutical composition for treating hemophilia, which comprises the antibody as an active ingredient. The antibody of the present invention, which binds specifically to TFPI, can activate the extrinsic pathway of blood coagulation by inhibiting TFPI. Thus, the antibody of the present invention can be effectively used for the treatment of antibody-induced hemophilia patients and for the prevention of blood coagulation disease in hemophilia-A or hemophilia-B patients.
    Type: Grant
    Filed: December 29, 2015
    Date of Patent: April 23, 2019
    Assignee: MOGAM INSTITUTE FOR BIOMEDICAL RESEARCH
    Inventors: Dong-Sik Kim, Mi Jung Lee, Jae Chan Park, Sumin Lee, Heechun Kwak, SungHo Hwang, Hyung-Kwon Lim, Kisu Kim, Young Seoub Park, Junhong Jeong, Ki Joon Cho
  • Patent number: 10265297
    Abstract: The present invention relates to a formulation of Spinacea oleracea useful for the prevention or treatment of osteo-health related disorders. The present invention relates to the field of pharmaceutical formulation that provides extract, fractions, pure compound isolated from natural sources and formulation thereof useful for the prevention and treatment of various medical indications. Further, this invention relates to conditions associated with estrogen dependent or independent diseases (primary/secondary osteoporosis) or syndromes or disorders preferably relating to cartilage such as osteoarthritis caused in humans and animals. Furthermore, this invention relates to achievement of peak bone mass during skeletal growth and health in humans and animals.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: April 23, 2019
    Assignee: Council of Scientific & Industrial Research
    Inventors: Ritu Trivedi, Prabhat Ranjan Mishra, Sulekha Adhikary, Naseer Ahmad, Dharmendra Choudhary, Naresh Mittapelly, Sudhir Kumar, Kapil Dev, Rakesh Maurya
  • Patent number: 10268882
    Abstract: Disclosed herein are an apparatus and method for recognizing a posture based on a distributed fusion filter. The apparatus for recognizing a posture based on a distributed fusion filter includes a calculation unit for generating first position information about a joint of a user by receiving measurement signals from multiple inertial sensors placed on a body of the user, a recognition unit for generating second position information using output information acquired in such a way that a vision sensor captures an image of the user, and a fusion unit for fusing the first position information with the second position information and generating final position information about the joint of the user using the fused information.
    Type: Grant
    Filed: July 24, 2017
    Date of Patent: April 23, 2019
    Assignee: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Soyeon Lee, Jae Hyun Lim, Sangjoon Park
  • Patent number: 10266564
    Abstract: The present invention relates to the cationic lipid cordiaroimide hybrid compounds of formula I. The present invention provides a process for preparation of these compounds is also being elaborated. The compounds described provides anticancerous activity against cell lines including PC-3 (prostate cancer), HepG2 (liver cancer), MCF-7 (breast cancer) and NIH-1/3T3 (non cancer cells. The compound was also capable of inducing caspase-3 mediated apoptosis in HepG2 cells by arresting the cell cycle in the G1 phase. Furthermore, the compound exhibited DNA ligase I inhibition. The present class of cationic lipid cordiarimide hybrids is likely to find specific use in developing novel targeted therapies for liver and prostate cancers.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: April 23, 2019
    Assignee: Council of Scientific & Industrial Research
    Inventors: Bathula Surendar Reddy, V.k.k. Durga Rao, Komal Sharma, M. Prathap Reddy, Dibyendu Banerjee, Deependra Kumar Singh
  • Patent number: 10270116
    Abstract: A high-temperature polymer electrolyte membrane fuel cell stack may include a plurality of cell units; a cooling assembly including a plurality of first independent cooling plates disposed on top surfaces of the plurality of cell units, respectively, and a plurality of second independent cooling plates disposed on bottom surfaces of the plurality of cell units, respectively; and a support assembly configured to support the plurality of cell units and the cooling assembly.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: April 23, 2019
    Assignee: Korea Institute of Energy Research
    Inventors: Young-Jun Sohn, Minjin Kim, Seung-Gon Kim, Gu-Gon Park, Byungchan Bae, Sung-Dae Yim, Seok-Hee Park, Tae-Hyun Yang, Won-Yong Lee, Chang-Soo Kim
  • Patent number: 10265440
    Abstract: The present invention relates to polymeric materials including a glycosaminoglycan networked with a polyolefin-containing polymer. The present invention also relates to hydrogels containing the polymeric materials. The present invention further relates to methods of synthesizing the polymeric materials and hydrogels of the present invention.
    Type: Grant
    Filed: March 23, 2017
    Date of Patent: April 23, 2019
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Susan P. James, Susan S. Yonemura, Ariane Vartanian
  • Patent number: 10265317
    Abstract: In one aspect, the invention relates to compositions comprising at least one creatine or creatine analog, at least one omega-3 fatty acid, and citicoline analogs. Also disclosed are methods of using same, alone or in combination with other agents, to treat depression disorders and associated maladies. Also disclosed are methods of using same, alone or in combination with other agents, to improve neuropsychological performance. Also disclosed are methods of using same, alone or in combination with other agents, to improve complexion. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: April 23, 2019
    Assignee: University of Utah Research Foundation
    Inventors: Perry Renshaw, Deborah Yurgelun-Todd
  • Patent number: 10265437
    Abstract: This disclosure relates to methods for promoting bone formation or reducing bone destruction. This disclosure also relates to methods for promoting the recruitment of mesenchymal stem cells (MSCs) to a local site of injury or surgical intervention in bone to promote healing. In addition, this disclosure relates to methods for reducing or preventing mineral formation or bone growth, or reducing bone mass. The methods disclosed herein are useful for treating conditions such as osteopetrosis or osteoradionecrosis.
    Type: Grant
    Filed: March 13, 2015
    Date of Patent: April 23, 2019
    Assignee: The Research Foundation for the State University of New York
    Inventors: Bryan S. Margulies, Sean D. Deboyace
  • Patent number: 10266776
    Abstract: A catalyst including between 50.0 and 99.8 percent by weight of iron, between 0 and 5.0 percent by weight of a first additive, between 0 and 10 percent by weight of a second additive, and a carrier. The first additive is ruthenium, platinum, copper, cobalt, zinc, or a metal oxide thereof. The second additive is lanthanum oxide, cerium oxide, magnesium oxide, aluminum oxide, silicon dioxide, potassium oxide, manganese oxide, or zirconium oxide.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: April 23, 2019
    Assignee: WUHAN KAIDI ENGINEERING TECHNOLOGY RESEARCH INSTITUTE CO., LTD.
    Inventors: Yilong Chen, Yanfeng Zhang, Jiangang Chen, Dechen Song, Juan Zhang, Taomei Sun
  • Patent number: 10266481
    Abstract: The present invention relates to a short enantioselective synthesis of 1-amino aryl tetraline compounds of Formula 1 via nucleophilic enamine catalysis using organocatalyst such as proline. wherein R1 and R2 represent independent of each other hydrogen, (un)substituted or substituted amine; R3 and R4 represent independent of each other hydrogen or halogen.
    Type: Grant
    Filed: June 22, 2015
    Date of Patent: April 23, 2019
    Assignee: Council of Scientific & Industrial Research
    Inventors: Venkataramasubramanian Vaithiyanathan, Rupali Gundappa Kalshetti, Sudalai Arumugam
  • Patent number: 10266544
    Abstract: The invention relates to aryl substituted aminomethyl spectinomycin analogs, derivatives thereof, and related compounds, which are useful as anti-bacterial agents; methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating anti-bacterial infections using the compounds and compositions.
    Type: Grant
    Filed: September 29, 2014
    Date of Patent: April 23, 2019
    Assignee: St. Jude Children's Research Hospital, Inc.
    Inventors: Richard E. Lee, Samanthi L. Waidyarachchi, David F. Bruhn, Jiuyu Liu, Zhong Zheng, Jason W. Rosch
  • Patent number: 10268661
    Abstract: Review systems and methods facilitate active reading by providing a flexible environment in which users can examine documents. A review system can comprise a virtual workspace, a document view region, a preview region, and optional document objects. The virtual workspace can simulate a desktop or other physical workspace. The document view region can display a portion of an open document at a magnification sufficient for reading. The preview region can display the document at a magnification sufficient to enable the general layout of the entire document to be determined. The document objects can be created from the document through tools of the review system. These document objects can be independently moveable throughout the virtual workspace as needed to facilitate the user's active reading process.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: April 23, 2019
    Assignee: Georgia Tech Research Corporation
    Inventors: Craig S. Tashman, W. Keith Edwards
  • Patent number: 10267270
    Abstract: A gas turbine system includes a turbine combustor, a turbine, an exhaust gas compressor, an exhaust gas recirculation (EGR) system, a carbon black recovery system, and a carbon black production controller. The carbon black production controller monitors data corresponding to a parameter of the carbon black. The carbon black production controller is also configured to adjust, based on the data, the fuel provided to the turbine combustor while maintaining a ratio of the fuel to the oxidant within a predetermined range to adjust the parameter of the carbon black.
    Type: Grant
    Filed: January 28, 2016
    Date of Patent: April 23, 2019
    Assignees: General Electric Company, ExxonMobil Upstream Research Company
    Inventors: Richard A. Huntington, William N. Yunker, Ilya Aleksandrovich Slobodyanskiy
  • Patent number: 10266420
    Abstract: Disclosed herein is a method comprising heating a strontium-containing compound using radiation in a first reactor; decomposing the strontium-containing compound into an oxide and carbon dioxide as a result of heat generated by the exposure to the radiation; reacting the oxide and the carbon dioxide in a second reactor; where the oxide and carbon dioxide react to produce heat; heating a working fluid using the heat produced in the second reactor; and driving a turbine with the heated working fluid to generate energy. Disclosed herein too is a composition comprising strontium carbonate; and strontium zirconate; where the mass ratio of strontium carbonate to strontium zirconate 2:8 to 8:2.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: April 23, 2019
    Assignee: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC
    Inventors: James Klausner, Kelvin Fnu Randhir, Nicholas AuYueng, Like Li, Nathan Rhodes, Amey Anand Barde, Renwei Mei, David Worthington Hahn
  • Patent number: 10266527
    Abstract: The present disclosure identifies compounds that bind to a t-RNA-dependent riboswitch of aaRS gene expression unique to Gram-positive bacteria. The compounds have anti-bacterial activity.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: April 23, 2019
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF ALBANY
    Inventor: Paul F. Agris
  • Patent number: 10266654
    Abstract: The present invention discloses polymeric ionic liquid (PIL) composition comprising a polymer selected from PBI or ABPBI and their derivatives or analogues covalently attached to fluorescence moiety selected from poly aromatic hydrocarbons, preferably pyrene or anthracene. Further, the invention discloses a process for preparing said composition with enhanced fluorescence and stability. Also, disclosed herein is the use of said fluorescent PIL in detection of explosives, as membranes for gas permeation and as chemo sensors.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: April 23, 2019
    Assignee: Council of Scientific & Industrial Research
    Inventors: Sayali Vinayak Shaligram, Ulhas Kanhaiyalal Kharul, Prakash Purushottam Wadgaonkar
  • Patent number: 10266405
    Abstract: The present invention provides a steam reforming process for heavy oil or hydrocarbons using a circulating fluidized bed reactor, the process having a reforming step and a regeneration step, wherein the reforming step and the regeneration step comprise a bubbling fluidized reactor containing a fluidizable nickel-containing reforming catalyst and produce hydrogen as a product of the reforming bed. The API gravity of the feedstock may be between ?11 and 54, preferably between ?11 and 20.
    Type: Grant
    Filed: April 28, 2015
    Date of Patent: April 23, 2019
    Assignee: TDA Research, Inc.
    Inventors: Girish Srinivas, Steven Charles Gebhard, Robert James Copeland
  • Patent number: 10266408
    Abstract: A metal-organic compound containing polymer matrix includes a polymer and a three-dimensional metal-organic framework includes a polydentate organic linker. The metal-organic compound containing polymer matrix is configured to continuously produce nitric oxide when exposed to a physiological fluid including a nitric oxide-releasing compound via a catalytic reaction catalyzed by the three-dimensional metal-organic framework.
    Type: Grant
    Filed: January 15, 2015
    Date of Patent: April 23, 2019
    Assignee: COLORADO STATE UNIVERSITY RESEARCH FOUNDATION
    Inventors: Melissa M. Reynolds, Benjamin P. Reynolds
  • Patent number: 10266546
    Abstract: A benzene compound is prepared by reacting a furan compound to produce an unsaturated bicyclic ether having an unsaturated carbon-carbon bond; hydrogenating the unsaturated carbon-carbon bond in the unsaturated bicyclic ether to produce a saturated bicyclic ether; and dehydrating and aromatizing the saturated bicyclic ether to produce the benzene compound.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: April 23, 2019
    Assignees: Avantium Knowledge Centre B.V., Stichting Wageningen Research
    Inventors: Jan Cornelis Van Der Waal, Edserd De Jong, Jacco Van Haveren, Shanmugam Thiyagarajan