Abstract: The present disclosure relates to a measurement device (1) for measuring a local parameter using an optical fiber element incorporating an array (100) of fiber Bragg gratings, FBGs, (101, 102, 103, 104), the measurement device (1) comprising: a semiconductor optical amplifier, SOA, (10), wherein the measurement device (1) is configured to be able to cause lasing at a respective lasing wavelength of said FBG (101, 102, 103, 104) of the FBG array (100); wherein the measurement device (1) further comprising: a filter element (40) configured with a wavelength dependent transmission coefficient; an output light sensing element (50) configured to detect said intensity of filtered light pulses from the filter element (40) and emit a corresponding electrical signal; processing means (60) for converting the electrical signal to the local parameter being measured for said one of the FBGs (101, 102, 103, 104) of the FBG array (100), and for providing the local parameter being measured.

Abstract: Disclosed are embodiments of shortest path search in an obstacle environment. Provided is a shortest path search method including: creating an epsilon graph; and determining k closest points from a query point on the basis of the graph, wherein the creating of the graph includes: creating a node group of nodes on the basis of a point group of arrival points; creating an edge group of edges on the basis of the created nodes; setting, on the basis of an obstacle group of at least one obstacle, whether each of the nodes is a valid node or a non-valid node; setting, on the basis of the obstacle group, whether each of the edges is a valid or non-valid edge; and including, for each of the arrival points, a particular arrival point on an anchor list of a valid node closest from the particular arrival point among the valid nodes.

Abstract: A shear-off device for a train coupler comprising a safety ring having an inner periphery formed with a thread for threaded engagement, and further comprising a radially inwards depending shear flange, the shear flange reaching in radial direction from the inner periphery towards the center axis of the safety ring, the shear flange having a flange base adjoining the inner periphery and a flange point reaching radially inside of the inner periphery.

Abstract: Disclosed herein are a pharmaceutical composition comprising an inhibitor of Olfr164 for the prevention or treatment of sepsis, a method for the prevention or treatment of sepsis, a use of Olfr164 as a marker for selecting sepsis therapeutic agents, a screening method for sepsis therapeutics using same, and a transgenic animal in which Olfr164 is knocked out. The composition comprising Olfr164 inhibitor can effectively prevent or treat sepsis. Additionally, sepsis therapeutics can be effectively screened by comparing the expression level or activity of Olfr164 before and after administering the candidate substance.

Abstract: An antenna-in-package with a heat dissipation structure includes a circuit board, an antenna substrate, a chip, a plurality of heat dissipation fins, a chassis, and dielectric fluid. The circuit board has a first surface and a second surface opposite to the first surface. The antenna substrate is disposed above the first surface of the circuit board. The chip is disposed between the antenna substrate and the first surface of the circuit board and is electrically connected to the antenna substrate. The plurality of heat dissipation fins protrude from the second surface of the circuit board. The chassis encapsulates the circuit board, the antenna substrate, the chip, and the plurality of heat dissipation fins. The dielectric fluid circulates and flows in the chassis through a cooling circulation device and is in direct contact with the plurality of heat dissipation fins.

Abstract: Provided are a diimide derivative represented by formula I, a preparation method therefor and the use thereof. The diimide derivative has a good anti-tumor activity, and the anti-proliferative activity against various cancer cells is significantly better than those of similar compounds.

Abstract: A method of preparing a composition comprising mycelium along with a cellulose and/or plurality of nanoparticles is described herein. The method comprises inoculating a liquid medium with fungus, the liquid medium comprising nutrients and the cellulose and/or nanoparticles. Further described herein are compositions comprising mycelium along with a cellulose and/or plurality of nanoparticles, as well as articles-of-manufacture comprising such a composition, wherein at least 10% of the cellulose and/or nanoparticles in the composition is incorporated within the mycelium. A method of enhancing fungal growth is also described, comprising contacting the fungus with a liquid medium comprising a polymer which comprises carboxylic acid groups.

Abstract: Disclosed are a device and method for audio signal processing. The audio signal processing device according to an embodiment includes a receiver configured to receive a bitstream corresponding to a compressed audio signal and a processor. The processor may be configured to generate a real restoration signal or a complex restoration signal by performing inverse quantization on real data of the bitstream or complex data of the bitstream, generate a result of real Frequency Domain Noise Shaping (FDNS) synthesis or a result of complex FDNS synthesis by performing FDNS synthesis on the real restoration signal or the complex restoration signal, and generate a restored audio signal by performing frequency-to-time transform on the result of the real FDNS synthesis or the result of the complex FDNS synthesis.

Abstract: “Herein disclosed is an ex vivo method of identifying a state of a tumor margin in a sample. The method comprises operating a system to generate an ultrasound image and a photoacoustic image, wherein the system comprises: a probe configured to deliver a pulsed laser from a laser source to a sample, wherein the laser source is operable to generate the pulsed laser; arrays coupled to the probe, wherein one of the arrays comprises transducing elements arranged thereon which are operable to transmit and collect ultrasound signals, and wherein one of the arrays comprises transducing elements arranged thereon which are operable to collect photoacoustic signals; and a data acquisition module which converts the ultrasound signals and the photoacoustic signals into the ultrasound image and the photoacoustic image, respectively.

Abstract: The present document describes antibodies or antigen-binding fragments that bind specifically to a target antigen, wherein the antibodies or antigen-binding fragments comprise complementarity determining regions (CDR1, CDR2 and CDR3) and an added O-glycosylation sequon glycosylated with an O-glycan having the general formula (I): wherein R1 is an initial N-acetylgalactosamine (GalNAc); n=1, or 2; R2 are each independently absent, galactose (Gal), GalNAc, N-Acetylglucosamine (GlcNAc), or a sialic acid; R3 are each independently absent, Gal or a sialic acid; and R4 are each independently absent or a sialic acid. Also described are compounds comprising the antibodies or antigen-binding fragments comprising a functional moiety operably linked to said O-glycan, compositions comprising the same, and methods of preparing such compounds.

Abstract: The present disclosure discloses a sensing function control node for an Internet of Things (IoT), and relates to technical field of electrical communication. The node includes an accessing module for sensors and actuators, a data format analyzing and integrating module and a transmission accessing and connecting module. Software-defined optical access technologies are utilized to control original sensing data in the IoT to access the accessing module for the sensors and the actuators. Status information of modules in the node is sensed in real time through a software-defined unified control plane, to adjust upload rates of modules and control the connections between sensing function control node and EAN. The original sensing data in IoT are transmitted to the transmission accessing and connecting module after being pre-processed. The pre-processed data are transmitted to EAN through upload channels between the sensing function control node and EAN established.

Abstract: Compositions for enhancing TFEB-mediated intracellular clearance are herein. Particularly, a complex comprising synergistic combination of polyamine and histidine-containing dipeptide present in a specific weight ratio along with pharmaceutically acceptable excipients is provided herein. More particularly, the composition comprises a synergistic blend of N-(3-Aminopropyl)-1,4-butanediamine and N-?-Acetyl-N-?-alanyl-L-histidine and salts thereof along with pharmaceutically acceptable excipients. Furthermore, the present synergistic composition is useful for improving or inducing autophagy, lysosomal biogenesis, mitophagy and lipophagy.

Abstract: The present disclosure generally relates to classes of compounds that bind the chromo-barrel domain of AT-rich interactive domain 4B (ARID4B). In some aspects, the compounds are of the Formula (II) as described herein, or a diamine composite thereof as set forth in Formula III herein. In some aspects, the compound is selected from compounds 1a, 1b, 1c, 1d, 1e, 2a, 2b, 2c, 2d, 2e, 2f, 2g, 2h, 2i, 2j, (as described herein) or combinations thereof. The present disclosure further considers administration of the compounds to target ARID4B in cells and for the treatment of cancerous breast tissue cells.

Abstract: A method of calibrating impedance of a memory device including a data transmitter includes: outputting a comparison signal by comparing a power supply voltage and a reference voltage, the power supply voltage being supplied to the data transmitter when the data transmitter is driven; storing a voltage level of the reference voltage when the comparison signal changes logical state; adjusting the reference voltage based on the comparison signal such that the voltage level of the reference voltage increases or decreases; and calibrating an output impedance of the memory device based on a digital code corresponding to an average reference voltage level, the average reference voltage level being obtained by averaging a prescribed number of voltage levels of the reference voltage stored as a result of repeatedly outputting the comparison signal, storing the voltage level of the reference voltage, and adjusting the reference voltage.

Abstract: An integrated circuit includes a phase shifted data generation circuit, a synchronization circuit, and a control signal generation circuit configured to generate a reference clock control signal that controls at least one of a phase and a frequency of the reference clock signal by performing a logical operation on a plurality of received synchronization data.

Abstract: The present invention provides an isolated nucleic acid molecule comprising, or consisting of, the nucleic acid sequence of SEQ ID NO:1, or of a nucleic acid sequence of at least 500 bp having at least 80% identity to said sequence of SEQ ID NO:1, wherein said isolated nucleic acid molecule leads to the specific expression in layer 2/3 of mouse cortex of an exogenous gene in a particular population of DLX4-positive cells when a nucleic acid sequence coding for said exogenous gene is operatively linked to said isolated nucleic acid molecule, said particular population of DLX4-positive cells being characterized in that it also expresses VTN, ABCC9 and CLDN5.

Abstract: A manufacturing method for a tin plate including a component design of low-carbon aluminum killed steel; under the condition of not increasing the alloy content and the production control difficulty, the content of elements such as C, Mn, Al and N in the tin plate is designed, and corresponding hot rolling, cold rolling, annealing and leveling processes are used; the strengthening effects of conventional elements, carbon and manganese, are fully utilized, aluminum nitride precipitation control in hot rolling is taken into account, a proper cold rolling reduction rate is selected, the ferrite grain size and cementite precipitation in steel are controlled by means of continuous annealing and over-aging treatment, and a specific temper rolling process is used, so that a tin plate having small strength and hardness fluctuations, a high elongation rate and a short yield plateau is produced.

Abstract: Codoped sodium-doped cesium iodide scintillators are described. The codoping can alter one or more optical and/or scintillation property of the scintillator material. For example, the codoping can increase scintillation light yield and/or decrease scintillation decay time. Radiation detectors comprising the scintillators, methods of detecting high energy radiation using the radiation detectors, and methods of altering one or more scintillation and/or optical properties of a cesium iodide scintillator are also described.

Abstract: Disclosed decoding method of the intra prediction mode comprises the steps of: determining whether an intra prediction mode of a present prediction unit is the same as a first candidate intra prediction mode or as a second candidate intra prediction mode on the basis of 1-bit information; and determining, among said first candidate intra prediction mode and said second candidate intra prediction mode, which candidate intra prediction mode is the same as the intra prediction mode of said present prediction unit on the basis of additional 1-bit information, if the intra prediction mode of the present prediction unit is the same as at least either the first candidate intra prediction mode or the second candidate intra prediction mode, and decoding the intra prediction mode of the present prediction unit.

Abstract: A method of a terminal may comprise: receiving, from a base station, information on Timing Advance (TA) groups, which are divided into groups, each having a specific unit size, based on a range for TAs occurring within a cell, and information on group-specific scheduling offsets mapped to the TA groups; calculating a pre-compensated TA based on satellite ephemeris information of the base station and location information of the terminal; identifying a group-specific scheduling offset mapped to a TA group corresponding to the pre-compensated TA; and transmitting a first uplink signal including a preamble to the base station using an uplink timing adjusted based on the group-specific scheduling offset.