Abstract: The present disclosure generally relates to a method for reducing the toxicity of polymyxins as a therapeutic agent comprising the step of coadministration of an aminoglycoside; a method for improving the aerosolization of an aminoglycoside comprising the step of combination formulation with a polymyxin; and a process for manufacturing a dry powder composition comprising a polymyxin and aminoglycoside. Pharmaceutical compositions and methods of treatment for lung infections are within the scope of this invention.

Abstract: Proposed are a coordination complex compound-ZIF complex and a method of preparing the same. More particularly, proposed are a coordination complex compound-ZIF complex, which is a complex on which a coordination complex compound is supported by being chemically and directly bonded to a metal vacancy site of a ZIF, capable of being usable as a heterogeneous catalyst that can be recovered and reused in subsequent processes and maintaining catalytic functions of the coordination complex compound, which is an active ingredient, and to a method of preparing the same.

Abstract: Provided for herein are polynucleotides, including codon-optimized polynucleotides, encoding genes for use in, for example, virally-mediated gene therapy for Friedreich's ataxia. Some embodiments related to viral vector constructs for use in such gene therapy. Also provided are dosing regimens and therapeutic combinations or systems for use in modulating immune responses to such viral vectors.

Abstract: A technique involves modular storage of network service plan components and provisioning of same. A subset of the capabilities of a service design system can be granted to a sandbox system to enable customization of service plan offerings or other controls.

Abstract: The present invention relates to a method and apparatus for setting a reference picture index of a temporal merging candidate. An inter-picture prediction method using a temporal merging candidate can include the steps of: determining a reference picture index for a current block; and inducing a temporal merging candidate block of the current block and calculating a temporal merging candidate from the temporal merging candidate block, wherein the reference picture index of the temporal merging candidate can be calculated regardless of whether a block other than the current block is decoded. Accordingly, a video processing speed can be increased and video processing complexity can be reduced.

Abstract: An apparatus for measuring blood components, includes: an impedance sensor configured to measure a bio-impedance of a user; and a processor configured to measure, by using a multiple-output artificial neural network (ANN) learning model, a concentration of a basic blood component and a concentration of at least one auxiliary blood component associated with the basic blood component, based on user metadata and the measured bio-impedance.

Abstract: A low dielectric sealing glass powder for a miniature radio-frequency glass insulator is made of the following raw materials expressed in molar percentages: SiO2: 70.5-74.0%, B2O3: 20.5-23.5%, Ga2O3: 0.5-2.0%, P2O5: 0.25-2.0%, Li2O: 0.4-6.0%, K2O: 0.1-1.5%, LaB6: 0.05-1.0%, and NaCl: 0.03-0.3%. The raw material components are simple, and the preparation method is easy to implement. The dielectric constant and dielectric loss of the prepared glass powder are low, and the melting and molding temperature is low, which are convenient for large-scale industrial production. The melting and molding temperature of the low dielectric sealing glass powder ranges from 1320° C. to 1360° C., and the obtained glass has a dielectric constant ranging from 3.8 to 4.1 and a dielectric loss ranging from 4×10?4 to 10×10?4 at a frequency of 1 MHz, and a sealing temperature ranging from 900° C. to 950° C.

Abstract: An aerosol generation assembly (10) includes an upright ceramic (100) and a heating element (200). The upright ceramic (100) includes a solid post (110) and at least one liquid-conducting projection (120) arranged on the solid post (110). A gas channel zone (101) is formed between a side wall of the liquid-conducting projections (120) and an outside wall of the solid post (110). A liquid passage zone (102) is formed on the liquid-conducting projection (120). The heating element (200) is at least partly arranged in the outside wall of the solid post (110) and located in the gas channel zone (101).

Abstract: The present invention relates to a carbon dioxide conversion process and, more particularly, to a continuous carbon dioxide conversion process and a system therefor.

Abstract: Autoregulatory systems that have been implemented to control the expression and activity of Cast 3d, including the activity of Cast 3d in vivo, thereby reducing collateral damage in cells at off-target sites (e.g., non-target messenger RNA transcripts. The autoregulatory system is in the form of a nucleic acid molecule comprising a zinc finger binding site, a promoter, and a nucleotide sequence encoding a Cast 3d fusion protein, and a transcriptional repressor domain, and wherein the Cast 3d fusion protein binds to the zinc finger binding site and represses transcription of the nucleotide sequence encoding the Cast 3d fusion protein.

Abstract: An apparatus for polymerase chain reaction (PCR) diagnosis for normalizing light source power and fluorescence power and an operating method thereof are disclosed.

Abstract: Disclosed herein is an Artificial Intelligence (AI) processor. The AI processor includes multiple NVM AI cores for respectively performing basic unit operations required for a deep-learning operation based on data stored in NVM; SRAM for storing at least some of the results of the basic unit operations; and an AI core for performing an accumulation operation on the results of the basic unit operation.

Abstract: An image restoration method, apparatus and device, and a storage medium are provided. The method comprises: evaluating, by an unsharpness evaluation network, an image to be processed, to generate an a feature map; inputting said image to be processed and the unsharpness feature map into a blur elimination main network; and iteratively processing, by the blur elimination main network, the image to be processed for a set number of times according to the unsharpness feature map to output a restored image. In the above-mentioned technical solution, an unsharpness feature of an image to be processed is extracted by using an unsharpness evaluation network, and iterative processing is performed on said image to be processed by using a blur elimination main network, where the networks are trained networks having corresponding functions, such that automatic restoration of an image can be realized, and image restoration efficiency and quality are improved.

Abstract: Fusion proteins, comprising at least one single chain antibody fragment (scFV), and a cancer antigen or marker, or a fragment thereof are provided. The scFV is capable of selectively binding to a cytokine released by chimeric antigen receptor (CAR) expressing cell such as interferon gamma (IFN-?) or tumor necrosis factor alpha (TNF-?). The cancer antigen or marker may comprise the extracellular domain of CD19. Methods for isolating or purifying CAR expressing cells using fusion proteins are provided.

Abstract: An electronic device and a method for diagnosing heart state based on electrocardiogram (ECG) are provided. An ECG file is obtained, and the ECG file is in a first file format and includes a plurality of potential traces of a plurality of leads. The ECG file is converted to a second file format to obtain electrocardiogram data corresponding to multiple leads. Each potential trace relative to time in the ECG file is converted to the ECG data of each lead. Integrated ECG data associated with the leads is generated based on the ECG data of the plurality of leads through the zero-padding operation and the stacking operation. A diagnostic result of heart status is generated based on the integrated ECG data and a deep learning model.

Abstract: An electrode that includes an elongate lead body and a nerve cuff. The nerve cuff may include a biologically compatible, elastic, electrically insulative helical cuff body configured to be disposed around a nerve, and a plurality of electrically conductive contacts carried by the helical cuff body that are spaced from one another.

Abstract: The invention provides prognostic methods for evaluating the severity of NMO and NMO-associated diseases as well as methods of treating NMO and NMO-associated diseases.

Abstract: A method of communication operation performed by a user equipment is provided. The method comprises: receiving a configuration, wherein the configuration comprises a resource setting; receiving a first set of resource comprising at least one resource, wherein the first set of resource is configured via the configuration; and performing a first operation, wherein the first operation is related to the first set of resource.

Abstract: Disclosed is a wireless communication system using multiple transmission and reception points. In a wireless communication system having a first transmission and reception point and at least one second transmission and reception point belonging to the same cell, the first transmission and reception point has a wider transmission area than the at least one second transmission and reception point, and the first transmission and reception point and the at least one second transmission and reception point generate downlink transmission signals by using the same physical layer cell ID or virtual cell IDs allocated to each terminal, and then the terminals generate uplink transmission signals by using the allocated virtual cell IDs.

Abstract: The present exemplary embodiments provide a positive electrode active material, a manufacturing method thereof, and a lithium secondary battery including the same. The positive electrode active material according to an exemplary embodiment is a metal oxide particle including a center and a surface portion positioned on the surface of the center, but the metal oxide particle is composed of a single particle, and the surface portion includes a film in which no peak is observed during XRD measurement.