Abstract: Embodiments of the present disclosure provide hierarchical, differential privacy enhancements to federated, machine learning. Local machine learning models may be generated and/or trained by data owners participating in the federated learning framework based on their respective data sets. Noise corresponding to and satisfying a first privacy loss requirement are introduced to the data owners' respective data sets, and noise corresponding to and satisfying a first privacy loss requirement are introduced to the local models generated and/or trained by the data owners. The data owners transmit model data corresponding to their respective local models to a coordinator, which in turn aggregates the data owners' model data. After introducing noise corresponding to and satisfying a third privacy loss requirement to the aggregated model data, the coordinator transmits the aggregated model data to the data owners to facilitate updating and/or re-training on their respective machine learning models.

Abstract: A solar module having on the front a cover plate with an outer surface and an inner surface is described. An optical interference layer for reflecting light within a predefined wavelength range is arranged on the inner surface. The inner surface and/or the outer surface have a patterned region. The patterned region has a height profile with hills and valleys, and a portion of the patterned region is composed of flat segments that are inclined relative to a plane of the cover plate.

Abstract: Provided herein are compositions and methods for accurate and scalable Primary Template-Directed Amplification (PTA) nucleic acid amplification and sequencing methods, and their applications for research, diagnostics, and treatment.

Abstract: Compositions comprising electrospun fibers and colorimetric detection encapsulated thereto are provided. Further, methods of use of said composition, including, but not limited to in-situ detection of molecules of interest, such as explosive compounds, are provided.

Abstract: Embodiments of the present invention provide a computer-implemented method of determining a scattering spectrum of an eye. The method comprises receiving data from a detector indicative of a reflected wave of radiation reflected from the retina, wherein the reflected wave of radiation is formed by an incident wave of masked radiation directed towards a retina of the eye, such that at least one region masked from the incident wave is present on the retina, determining a first back scattering spectrum indicative of light scattered from an optical media of the eye in dependence on a portion of the reflected wave of radiation corresponding to the at least one masked region, determining a second back scattering spectrum indicative of light scattered from a neural retina of the eye in dependence on retinal structure information representative of neural retinal structure, and determining the scattering spectrum of the eye in dependence on the first back scattering spectrum and the second back scattering spectrum.

Abstract: Fiber optic connectors comprising multiple footprints along with cable assemblies and methods for making the same are disclosed. In one embodiment, the optical connector comprises a housing and a ferrule. The housing comprises a longitudinal passageway between a rear end and a front end. The fiber optic connector may be converted from a first footprint to a second footprint by a conversion housing that fits about a portion of the housing. The optical connectors disclosed may be tunable for improving optical performance and may also include a spring for biasing the ferrule to a forward position as desired.

Abstract: The present disclosure provides the use of compounds of Formulae (I), (II), (III), (III-A), and (III-B) (e.g., metformin) in treating a neurological disease associated with repeat expansions and/or RAN protein accumulation, reducing the level of one or more repeat associated non-ATG (RAN) proteins, and reducing the accumulation of RAN proteins in a subject and/or biological sample. Also provided is the use of compounds of Formulae (I), (II), (III), (III-A), and (III-B) (e.g., metformin) in inhibiting RAN protein translation in a subject and in a biological sample (e.g., cells, tissue). Also provided in the present disclosure are pharmaceutical compositions, Skits, and uses of compounds of Formulae (I), (II), (III), (III-A), and (III-B) (e.g., metformin) for treating diseases associated with repeat expansions.

Abstract: The present disclosure provides systems and methods of controlling a magnetically confined plasma sputtering process using the waste heat transferred from the plasma into the target material and then into thermally controlled magnetic field adjustment assemblies that modify the strength of the plasma confinement magnetic fields on the target material.

Abstract: Systems and methods are described for supporting an appendage or spine. In one embodiment, a support for a spine comprises a support body configured to align with a spinal column of a wearer further comprising a plurality of modular flexible support body segments configured to align with regions of the spinal column, a plurality of straps disposed along a longitudinal axis of the support body, and a support member disposed adjacent the support body to provide rigidity to the support body. The support member acts as a cantilever configured to distribute a corrective force along the length of the support body.

Abstract: The present disclosure relates to a display apparatus including a display panel, a bezel surface formed on a boundary of the display panel, and an antenna located on the bezel surface, wherein the antenna includes an antenna body extending in a horizontal direction to the bezel surface, an extension body provided on one side or opposite sides of the antenna body, and a frequency variable device configured to selectively electrically connect the antenna body and the extension body.

Abstract: A bioprinter and methods of using the bioprinter. The bioprinter permits selective three-dimensional movement of multiple nozzle assemblies during operation of the bioprinter. The bioprinter can be used to produce scaffold-free tissue constructs having a plurality of cellular elements interspersed among a semi-permeable vascular network. The bioprinter can also be used to print a tissue construct directly onto a tissue defect of a subject. The bioprinter can be provided as part of a bioprinting system that includes a scanner for imaging the tissue defect.

Abstract: Methods and systems are provided for increasing a quality of computed tomography (CT) images reconstructed from high helical pitch scans. In one embodiment, the current disclosure provides for a method comprising generating a first computed tomography (CT) image from projection data acquired at a high helical pitch; using a trained multidimensional statistical regression model to generate a second CT image from the first CT image, the multidimensional statistical regression model trained with a plurality of target CT images reconstructed from projection data acquired at a lower helical pitch; and performing an iterative correction of the second CT image to generate a final CT image.

Abstract: A communication terminal and a method of providing a unified natural language interface to the same are disclosed. The method includes: determining, when text information containing many characters is created, whether the text information conforms to one of preset grammatical constraints; extracting, when the text information conforms to one of the grammatical constraints, tokens of one or more of characters from the text information, and extracting, when the text information does not conform to one of the grammatical constraints, one or more characters having an attribute probability higher than a reference probability as a token; and analyzing the extracted tokens to determine a function to handle the extracted tokens, and executing the determined function based on the extracted tokens.

Abstract: According to an embodiment, there is provided a method for mitigating seawater intrusion in the ground where an aquifer having a seawater-fresh water interface is formed, the method including: installing an injection well at a point on an inland area, spaced apart from the sea by a predetermined distance, to a predetermined injection depth (d), the injection well having a predetermined screen height; injecting seawater into the aquifer by a predetermined quantity of injection through the injection well; and forming an upper seawater area around the injection well by the injection of the seawater, wherein the upper seawater area is an area that is filled with seawater in an upper portion of the aquifer.

Abstract: The present invention concerns the use of compounds and compositions for the treatment or prevention of Flavivirus infections, such as dengue virus infections and Zika virus infections. Aspects of the invention include methods for treating or preventing Flavivirus virus infection, such as dengue virus and Zika virus infection, by administering a compound or composition of the invention, to a subject in need thereof; methods for inhibiting Flavivirus infections, such as dengue virus and Zika virus infections, in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits useful for treating or preventing Flavivirus infections, such as dengue virus and Zika virus infections.

Abstract: Microfluidic devices and methods that utilize ion concentration polarization within water-in-oil nanoliter scale droplets for concentration enrichment, separation, and substitution of charges species are disclosed. Such devices and methods can be used for separation of multiple species by mobility of each species and for the alteration and manipulation of the droplet composition by ion exchange.

Abstract: Devices and methods for the treatment of heart conditions, and other medical purposes, include cardiac pacing systems. For example, this document describes temporary transvenous endocardial pacemaker systems and devices for deploying such systems without the need for conventional imaging procedures.

Abstract: An antimicrobial formulation that can be directly added into a composition or onto a surface of a composition (e.g., forming a surface coating on a composition or device). The antimicrobial formulation includes sodium pentaborate, di-sodium tetraborate decahydrate, titanium diborite, titanium borate, sodium pyrithione, zinc pyrithione, benzhetonium chloride, or any combination thereof.