Patents Assigned to Research
  • COMPOUNDS AND METHODS OF USE
    Publication number: 20140005190
    Abstract: In one aspect, the present invention provides for a compound of Formula I in which in Formula I, the variables X1, X2a, X2b, X2c, R1, B, L, E, A and the subscript n are as defined herein. In another aspect, the present invention provides for pharmaceutical compositions comprising compounds of Formula I as well as methods for using compounds of Formula I for the treatment of diseases and conditions (e.g., cancer, thrombocythemia, etc) characterized by the expression or over-expression of Bcl-2 anti-apoptotic proteins, e.g., of anti-apoptotic Bcl-xL proteins.
    Type: Application
    Filed: June 27, 2013
    Publication date: January 2, 2014
    Applicants: Genentech, Inc., The Walter and Eliza Hall Institute of Medical Research, AbbVie Inc.
    Inventors: JONATHAN BAYLDON BAELL, CHINH THIEN BUI, PETER COLMAN, DANETTE A. DUDLEY, WAYNE J. FAIRBROTHER, JOHN A. FLYGARE, GUILLAUME LAURENT LESSENE, CHUDI NDUBAKU, GEORGE NIKOLAKOPOULOS, CARL STEVEN RYE, BRAD EDMUND SLEEBS, BRIAN JOHN SMITH, KEITH GEOFFREY WATSON, STEVEN W. ELMORE, ANDREW M. PETROS, ANDREW J. SOUERS, PETER CZABOTAR
  • LIQUID CRYSTAL GAS SENSOR CELL AND THE USE THEREOF
    Publication number: 20140004004
    Abstract: A gas sensor cell using a liquid crystal composite material is provided. The gas sensor cell has recovery capability and can be reused. Upon gas adsorption, the liquid crystal composite material has visually detectable color changes and changes in electrical properties to facilitate the measurement of gas concentration from low to high.
    Type: Application
    Filed: August 30, 2013
    Publication date: January 2, 2014
    Applicant: Industrial Technology Research Institute
    Inventors: Chin-Kai Chang, Hui-Lung Kuo
  • DETOXIFIED PNEUMOCOCCAL NEURAMINIDASE AND USES THEREOF
    Publication number: 20140004138
    Abstract: Provided herein are compositions designed to reduce or prevent bacterial infections (for example pneuomococcal infections), nasal carriage, nasal colonization, and central nervous system invasion. Provided herein is a composition comprising a polypeptide comprising the amino acid sequence of SEQ ID NO:19 or a variant thereof that can elicit an anti-neuraminidase immune response. Further provided are methods of making and using the compositions disclosed herein. Specifically provided are methods of generating antibodies in a subject comprising administering to the subject an agent or composition taught herein. Also provided are methods of reducing or preventing nasal carriage or pneumococcal infection in a subject comprising administering to the subject a composition taught herein.
    Type: Application
    Filed: November 7, 2012
    Publication date: January 2, 2014
    Applicant: THE UAB RESEARCH FOUNDATION
    Inventors: David E. Briles, Susan K. Hollingshead
  • TOUCH-SENSITIVE DISPLAY AND METHOD
    Publication number: 20140002371
    Abstract: A touch-sensitive apparatus includes a first material, a second material joined to the first material such that the first material and the second material are substantially flat across an interface between the first material and the second material, and first touch sensors disposed continuously across the interface from the first material to the second material.
    Type: Application
    Filed: June 28, 2012
    Publication date: January 2, 2014
    Applicant: RESEARCH IN MOTION LIMITED
    Inventor: Aaron Robert ALLEN
  • SYSTEM AND METHOD FOR LOCALIZING DATA FIELDS ON STRUCTURED AND SEMI-STRUCTURED FORMS
    Publication number: 20140003721
    Abstract: A method and system to localize data fields of a form. An image of a form is received, where the form includes data fields. Word boxes of the image are identified. The word boxes are grouped into candidate zones, where each of the candidate zones includes one or more of the word boxes. Hypotheses are formed from the data fields and the candidate zones, where each hypothesis assigns one of the candidate zones to one of the data fields or a null data field. A constrained optimization search of the hypotheses is performed for an optimal set of hypotheses. The optimal set of hypotheses assigns word box groups to corresponding data fields.
    Type: Application
    Filed: June 29, 2012
    Publication date: January 2, 2014
    Applicant: PALO ALTO RESEARCH CENTER INCORPORATED
    Inventor: Eric Saund
  • SYSTEMS AND METHODS FOR INDIVIDUALLY TRAPPING PARTICLES FROM AIR AND MEASURING THE OPTICAL SPECTRA OR OTHER PROPERTIES OF INDIVIDUAL TRAPPED PARTICLES
    Publication number: 20140004559
    Abstract: Embodiments of the present invention are directed to systems and methods for continuously sampling particles from air. In one embodiment, a system for continuously sampling particles from air may include: an airflow system configured to continuously draw air including airborne particles into the system; a photophoretic trap that uses photophoretic forces of a laser beam to trap one or more of the airborne particles from the drawn air; a measurement device configured to measure one or more properties of the trapped one or more airborne particles; and a controller configured to repeatedly trap, measure and release one or more airborne particles.
    Type: Application
    Filed: March 11, 2013
    Publication date: January 2, 2014
    Applicant: U.S. ARMY RESEARCH LABORATORY ATTN: RDRL-LOC-I
    Inventors: Steven C. Hill, Yongle Pan
  • Text Detection Devices and Text Detection Methods
    Publication number: 20140003723
    Abstract: A text detection device is provided. The text detection device may include: an image input circuit configured to receive an image; an edge property determination circuit configured to determine a plurality of edge properties for each of a plurality of scales of the image; and a text location determination circuit configured to determine a text location in the image based on the plurality of edge properties for the plurality of scales of the image.
    Type: Application
    Filed: June 24, 2013
    Publication date: January 2, 2014
    Applicant: Agency for Science, Technology and Research
    Inventors: Shijian LU, Joo Hwee LIM
  • FEW-LAYER GRAPHENE NANORIBBON AND A METHOD OF MAKING THE SAME
    Publication number: 20140004327
    Abstract: A method of preparing graphene nanoribbons from a few-layer graphene film includes the steps of growing or placing a few-layer graphene film on a substrate, applying nanoparticles to a surface of the few-layer graphene layer on the substrate and performing chemical vapor etching. The resulting few-layer graphene nanoribbon has a thickness of between about 0.3 nm and about 50.0 nm and a width of between about 1.0 nm and about 20.0 nm.
    Type: Application
    Filed: June 29, 2012
    Publication date: January 2, 2014
    Applicant: THE UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION
    Inventors: Douglas Robert Strachan, Joseph Kelly Stieha, David Patrick Hunley, Stephen Lee Johnson, JR.
  • HOME CLOUD GATEWAY APPARATUS FOR MULTI-SERVICE AND METHOD OF PROVIDING SERVICE USING THE SAME
    Publication number: 20140003340
    Abstract: A home cloud gateway apparatus that is connected to an indoor home network and that provides a service to a client that connects through the network includes an Internet interface unit, a phone exchange unit, a storage unit that stores a virtual computer module, and an authentication processor. The home cloud gateway apparatus provides a virtual computer service by activating the virtualization module that is stored at the storage unit, and provides a phone call service through the Internet and a phone call service through the Internet and a phone network using the Internet interface unit and the phone exchange unit.
    Type: Application
    Filed: January 29, 2013
    Publication date: January 2, 2014
    Applicant: Electronics and Telecommunications Research Institute
    Inventor: Electronics and Telecommunications Research Institute
  • POSITION-BASED CONTEXT SELECTION FOR GREATER-THAN-ONE FLAG DECODING AND ENCODING
    Publication number: 20140003488
    Abstract: Methods of encoding and decoding for video data for encoding or decoding a sequence of greater-than-one flags for a coefficient group are provided. Context-based encoding and decoding selects a context for encoding or decoding the greater-than-one flag based upon the position of the greater-than-one flag in the sequence of greater-than-one flags. Selection of the context may also be based upon the position of the last-non-zero coefficient in the coefficient group.
    Type: Application
    Filed: February 25, 2013
    Publication date: January 2, 2014
    Applicant: RESEARCH IN MOTION LIMITED
    Inventors: Tianying JI, Xiang YU, Dake HE
  • Method of Using Cytokine Assays to Diagnose, Treat, and Evaluate Inflammatory Disease
    Publication number: 20140005071
    Abstract: The invention provides methods for diagnosing, treating, or evaluating inflammatory and autoimmune diseases by sampling peripheral blood, serum, plasma, tissue, cerebrospinal fluid, or other bodily fluids from a human subject having a suspected diagnosis. The sample is analyzed for the presence and amount of certain cytokines, which provides the diagnosis, prognosis or evaluation of therapeutic response.
    Type: Application
    Filed: September 3, 2013
    Publication date: January 2, 2014
    Applicants: Oklahoma Medical Research Foundation, The Board of Regents of the University of Oklahoma
    Inventors: Cherie M. Chappell, Michael B. Centola, Philip J. Alex, Kenneth Hensley
  • METHOD TO ENHANCE SWALLOWING SAFETY AND APPEAL OF BEVERAGES FOR TREATING DYSPHAGIA BASED ON RHEOLOGICAL AND SENSORY PARAMETERS
    Publication number: 20140004045
    Abstract: An edible composition of matter having an apparent viscosity of from about 150 cP to about 2000 cP at about 30 s?1; a yield stress of from 0 Pa to about 20 Pa at 1 s?1; and a flow index of from about 0.2 to about 0.6. The composition may include an imaging agent. The compositions are useful for providing sustenance to dysphagic subjects and for evalualuating dysphagia.
    Type: Application
    Filed: March 14, 2013
    Publication date: January 2, 2014
    Applicants: Regents of the University of Minnesota, Wisconsin Alumni Research Foundation
    Inventors: Heather N. Mendenhall, Richard W. Hartel, JoAnne Robbins, Jacqueline A. Hind, Zata M. Vickers
  • APPARATUS AND METHOD FOR PROVIDING STREAMING CONTENT USING REPRESENTATIONS
    Publication number: 20140006564
    Abstract: A method and apparatus for an adaptive Hypertext Transfer Protocol (HTTP) streaming service using metadata of media content are provided. The media content may include a sequence of one or more periods. Each of the periods may include one or more representations. The metadata may include information used to describe a relationship between the representations, and include information for terminals having different display bit depths.
    Type: Application
    Filed: March 16, 2012
    Publication date: January 2, 2014
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Truong Cong Thang, Jin Young Lee
  • METHOD OF PURIFYING EXOSOMES
    Publication number: 20140004601
    Abstract: We describe a method of purifying a mesenchymal stem cell particle such as an exosome, the method comprising separating the mesenchymal stem cell particle on the basis of its negative charge. The method may comprise (a) providing a composition comprising mesenchymal stem cell particles such as a mesenchymal stem cell conditioned medium (MSC-CM); (b) applying the composition comprising mesenchymal stem cell particles to an ion exchange resin to enable mesenchymal stem cell particles to bind to the ion exchange resin; and (c) eluting bound mesenchymal stem cell particles. The ion exchange resin may comprise an anion exchange resin such as an anion exchange spin column.
    Type: Application
    Filed: December 19, 2011
    Publication date: January 2, 2014
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventor: Sai Kiang Lim
  • Processes For The Production of Methanol Using Sweep-Based Membrane Separation Steps
    Publication number: 20140005285
    Abstract: Disclosed herein are methanol production processes that include a sweep-based membrane separation step using a membrane that is selective to carbon dioxide over hydrogen. Using the processes of the invention, the efficiency of methanol production from syngas is increased by reducing the compression requirements of the process and/or improving the methanol product yield. In certain embodiments, a hydrogen-rich stream is generated; this hydrogen-rich stream can be sent for other uses. An additional benefit is that the processes of the invention may debottleneck existing methanol plants if more syngas or carbon dioxide is available, allowing for feed of imported carbon dioxide into the synthesis loop. This is a way of sequestering carbon dioxide.
    Type: Application
    Filed: March 14, 2013
    Publication date: January 2, 2014
    Applicant: Membrane Technology and Research, Inc.
    Inventor: Nicholas P. Wynn
  • Method of Viral Production in Cells
    Publication number: 20140004568
    Abstract: A method of using a cell to produce virus is provided involving growing cells under hyperosmotic conditions during growth phase of the cells, infecting or transfecting the cells grown under hyperosmotic conditions with a virus, and maintaining the infected or transfected cells under less stressful conditions during a production phase of the infected or transfected cells to produce more of the virus. Viral productivity is improved by this method.
    Type: Application
    Filed: February 15, 2012
    Publication date: January 2, 2014
    Applicant: National Research Council of Canada
    Inventors: Chun Fang Shen, Amine Kamen
  • IMAGE ENCODING METHOD USING A SKIP MODE, AND A DEVICE USING THE METHOD
    Publication number: 20140003518
    Abstract: Disclosed are an image encoding method using a skip mode and a device using the method. The image encoding method may comprise the steps of: judging whether there is residual block data of a prediction target block on the basis of predetermined data indicating whether residual block data has been encoded; and, if there is residual block data, restoring the prediction target block on the basis of the residual block data and an intra-screen predictive value of the prediction target block. Consequently, encoding and decoding efficiency can be increased by carrying out the encoding and decoding of screen residual data only for prediction target blocks where there is a need for a residual data block in accordance with screen similarity.
    Type: Application
    Filed: April 12, 2012
    Publication date: January 2, 2014
    Applicant: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE
    Inventors: Gun Bang, Won Sik Cheong, Gi Mun Um, Nam Ho Hur, Gwang Hoon Park, Kyung Yong Kim
  • METHOD OF DEVICE-TO-DEVICE COMMUNICATION IN WIRELESS MOBILE COMMUNICATION SYSTEM
    Publication number: 20140004867
    Abstract: A device-to-device (D2D) communication method in a wireless mobile communication system is provided. A channel state measurement method for adaptive transmission of cellular network-based D2D communication, a data transmission/reception method of D2D communication, and a power control method for transmission power control of a D2D link in the D2D communication are provided. Specifically, cellular network-based D2D communication methods optimized for a Third Generation Partnership Project (3GPP) Long Term Evolution (LTE) system are provided. The above-described methods are also applicable to various cellular mobile communication systems as well as the 3GPP LTE system.
    Type: Application
    Filed: January 23, 2013
    Publication date: January 2, 2014
    Applicant: Electronics and Telecommunications Research Institute
    Inventor: Electronics and Telecommunications Research Institute
  • SCALE CHANGING DETECTION AND SCALING RATIO DETERMINATION BY USING MOTION INFORMATION
    Publication number: 20140003741
    Abstract: This invention discloses a method for determining an area scaling ratio of an object in a video image sequence. In one embodiment, a centroid of the object is determined. One or more directed straight lines are selected, each passing through the centroid, extending from an end of the object's boundary to an opposite end thereof, and having a direction that is upward. A length scaling ratio for each directed straight line is determined by: determining a motion vector for each selected pixel on the line; computing a scalar component of the motion vector projected onto the line; estimating a change of the line's length according to the scalar components obtained for all pixels; and determining the length scaling ratio according to the change of the line's length. The area scaling ratio is computed based on the length scaling ratios for all directed straight lines.
    Type: Application
    Filed: June 29, 2012
    Publication date: January 2, 2014
    Applicant: Hong Kong Applied Science and Technology Research Institute Company Limited
    Inventors: Chunhui Cui, Chun-Fu Chen, Ciao-Siang Siao, Gwo Giun LEE, Yan Huo
  • MULTI-SEGMENTED INFLATABLE BRACHYTHERAPY DEVICES, SYSTEMS, AND METHODS OF USING THE SAME
    Publication number: 20140005539
    Abstract: Provided are multi-segmented inflatable brachytherapy devices. Also provided are systems and methods including multi-segmented inflatable brachytherapy devices.
    Type: Application
    Filed: March 16, 2012
    Publication date: January 2, 2014
    Applicant: H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE INC
    Inventors: Kenneth M. Forster, Matthew C. Biagioli