Patents Assigned to Rhone-Poulenc Rorer S.A.
  • Publication number: 20040009592
    Abstract: The invention concerns human neural progenitor cells containing introduced genetic material encoding a product of interest, and their use for the treatment of neurodegenerative diseases.
    Type: Application
    Filed: November 27, 2002
    Publication date: January 15, 2004
    Applicant: Rhone-Poulenc Rorer S.A.
    Inventors: Olivier Sabate, Philippe Horellou, Marie-Helene Buc-Caron, Jacques Mallet
  • Publication number: 20030059455
    Abstract: A defective recombinant adenovirus including at least one DNA sequence coding for all or an active part of a superoxide dismutase or a derivative thereof. The therapeutical use thereof and corresponding pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: January 13, 1997
    Publication date: March 27, 2003
    Applicant: RHONE-POULENC RORER S.A.
    Inventors: MARTINE BARKATS, JACQUES MALLET, MICHEL PERRICAUDET, FREDERIC REVAH
  • Publication number: 20030055031
    Abstract: Methods of using compounds of formula (I): 1
    Type: Application
    Filed: July 25, 2002
    Publication date: March 20, 2003
    Applicant: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Claude Hardy, Jean Bouquerel, Patrick Nemecek, Jean-Claude Aloup, Serge Mignani, Jean-Francois Peyronel
  • Publication number: 20020051828
    Abstract: The present invention relates to mixtures which can be isolated from grains of Eugenis Jambolana Lamarck, the preparation of such mixtures, the medicaments containing said mixtures or constituents of said mixtures, and the use of these mixtures and constituents for the preparation of a medicament.
    Type: Application
    Filed: December 12, 2000
    Publication date: May 2, 2002
    Applicant: RHONE-POULENC RORER S.A. and INSTITUT MALGACHE DE RECHERCHES APPLIQUEES
    Inventors: Albert Rakoto Ratsimamanga, Suzanne Rakoto Ratsimamanga, Philippe Rasoanaivo, Jean Leboul, Jean Provost, Daniel Reisdorf
  • Publication number: 20020031493
    Abstract: Recombinant adenoviruses comprising a heterologous DNA sequence coding for glial-derived neurotrophic factor (GDNF), preparation thereof, and use thereof for treating and/or preventing degenerative neurological diseases.
    Type: Application
    Filed: August 1, 1997
    Publication date: March 14, 2002
    Applicant: RHONE-POULENC RORER S.A.
    Inventors: PHILIPPE HORELLOU, JACQUES MALLET, MICHEL PERRICAUDET, FREDERIC REVAH, EMMANUELLE VIGNE
  • Publication number: 20020006660
    Abstract: The invention concerns human neural progenitor cells containing introduced genetic material encoding a product of interest, and their use for the treatment of neurodegenerative diseases.
    Type: Application
    Filed: February 28, 1997
    Publication date: January 17, 2002
    Applicant: Rhone-Poulenc Rorer, S.A.
    Inventors: OLIVIER SABATE, PHILIPPE HORELLOU, MARIE-HELENE BUC-CARON, JACQUES MALLET
  • Publication number: 20010051736
    Abstract: New taxoids of general formula (I): 1
    Type: Application
    Filed: January 3, 2001
    Publication date: December 13, 2001
    Applicant: Rhone-Poulenc Rorer,S.A.
    Inventors: Herve Bouchard, Jean-Dominique Bourzat, Alain Commercon
  • Publication number: 20010039046
    Abstract: Novel adenovirus-derived viral vectors, the preparation thereof, and their use in gene therapy, are disclosed. In particular, recombinant adenoviruses including an adenovirus genome wherein (i) the E1 region is inactivated, (ii) the genomic organization is modified, and (iii) optional recombination with the producing line genome generates non-viable viral particles, are disclosed.
    Type: Application
    Filed: January 26, 2001
    Publication date: November 8, 2001
    Applicant: Rhone-Poulenc Rorer S.A.
    Inventors: Patrice Yeh, Michel Perricaudet, Cecile Orsini
  • Patent number: 6312946
    Abstract: Novel adenovirus-derived viral vectors, the preparation thereof, and their use in gene therapy, are disclosed. In particular, recombinant adenoviruses including an adenovirus genome wherein (i) the E1 region is inactivated, (ii) the genomic organization is modified, and (iii) optional recombination with the producing line genome generates non-viable viral particles, are disclosed.
    Type: Grant
    Filed: April 22, 1997
    Date of Patent: November 6, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Patrice Yeh, Michel Perricaudet, Cécile Orsini
  • Patent number: 6291679
    Abstract: The present invention relates to a novel process for the preparation of benzoperhydroisindole compounds.
    Type: Grant
    Filed: July 26, 1999
    Date of Patent: September 18, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Patrick Mailliet, Christophe Salagnad
  • Patent number: 6287762
    Abstract: Method for double-stranded DNA purification, by which a solution containing said DNA in a mixture with other components is passed over a support on which is covalently coupled in oligonucleotide capable of hybridizing with a specific sequence present on said DNA to form a triple helix.
    Type: Grant
    Filed: June 9, 1997
    Date of Patent: September 11, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Joël Crouzet, Daniel Scherman, Pierre Wils
  • Patent number: 6288075
    Abstract: Compounds of formula (I): their racemates, enantiomers, diastereoisomers and inorganic acid salts and organic acid salts thereof, processes for preparing them and the medicaments containing them are discussed.
    Type: Grant
    Filed: August 27, 1999
    Date of Patent: September 11, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Claude Hardy, Jean Bouquerel, Patrick Nemecek, Jean-Claude Aloup, Serge Mignani, Jean-François Peyronel
  • Publication number: 20010014319
    Abstract: Defective recombinant viruses containing an inserted gene coding for all or part of lecithin-cholesterol acyltransferase (LCAT) or a variant thereof, pharmaceutical compositions containing said viruses, and the use thereof for treating or preventing dyslipoproteinaemia-related diseases, are disclosed.
    Type: Application
    Filed: November 5, 1997
    Publication date: August 16, 2001
    Applicant: RHONE-POULENC RORER S.A.
    Inventors: PATRICE DENEFLE, NICOLAS DUVERGER, MARTINE LATTA-MAHIEU, SANDRINE SEGURET
  • Patent number: 6261807
    Abstract: A novel method for preparing recombinant adenoviruses and the use of such adenoviruses in gene therapy are disclosed. Plasmids used in the construction of said adenoviruses are also disclosed.
    Type: Grant
    Filed: August 8, 1997
    Date of Patent: July 17, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Joël Crouzet, Laurent Naudin, Patrice Yeh, Cécile Orsini, Emmanuelle Vigne
  • Patent number: 6239270
    Abstract: The present invention relates to the isolation of a cDNA clone encoding the calcium sensor in human placenta and subsequent Northern blots confirming the mRNA expression also in human parathyroid and kidney tubule cells. Close sequence similarity is demonstrated with the rat Heymann nephritis antigen, a glycoprotein of the kidney tubule brush border with calcium binding ability. Immunohistochemistry substantiates a tissue distribution of the calcium sensor protein similar to that previously described for the Heymann antigen. It is proposed that the identified calcium sensor protein constitutes a universal sensor for recognition of variation in extracellular calcium, and that it plays a key role for calcium regulation via different organ systems. The calcium sensor protein belongs to the LDL-superfamily of glycoproteins, claimed to function primarily as protein receptors, but with functionally important calcium binding capacity.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: May 29, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Göran Akerström, Claes Juhlin, Lars Rask, Göran Hjälm, Clarence C. Morse, Edward M. Murray, Gregg R. Crumley
  • Patent number: 6235497
    Abstract: A nucleic sequence coding for a protein involved in the vesicular transport of acetylcholine, the corresponding protein and the promoter sequences implicated in expressing said protein are disclosed. The invention also discloses expression vectors containing said sequence and the therapeutic use of said sequence or said vectors.
    Type: Grant
    Filed: April 21, 1997
    Date of Patent: May 22, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Stéphane Bejanin, Sylvie Berrard, Riccardo Cervini, Jacques Mallet
  • Patent number: 6210879
    Abstract: The present invention relates to a method for diagnosing schizophrenia, said method being based on the detection in vitro of the presence of the allele Ep of the microsatellite HUNTH01 in the gene TH. The invention also relates to the primers used for implementing said method.
    Type: Grant
    Filed: December 22, 1997
    Date of Patent: April 3, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Rolando Meloni, Claudine Laurent, Jacques Mallet
  • Patent number: 6210963
    Abstract: Cell compositions containing mononuclear phagocyte systems cells, and their use in cell therapy, e.g. adoptive immunotherapy, are disclosed.
    Type: Grant
    Filed: April 24, 1996
    Date of Patent: April 3, 2001
    Assignees: Institut National de la Sante et de la Recherche Medicale, Rhone-Poulenc Rorer S.A.
    Inventors: Hedi Haddada, Manuel Lopez, Michel Perricaudet
  • Patent number: 6207675
    Abstract: The invention concerns pyrrole derivatives of general formula (I) useful for treatment and prevention of diseases in which are involved viruses of the herpes family and/or cytokines in particular TNF&agr;.
    Type: Grant
    Filed: June 11, 1999
    Date of Patent: March 27, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: Jean-Christophe Carry, Serge Mignani, Conception Nemecek
  • Patent number: 6197980
    Abstract: 4-acetoxy-2&agr;-benzoyloxy-5&bgr;, 20-epoxy-1&bgr;, 7&bgr;, 10&bgr;-trihydroxy-9-oxo-11-taxen-13&agr;-y1(2R,3S)-3-t-butoxycarbonylamino-3-phenyl-2-hydroxypropionate trihydrate obtained by a process of centrifugal partition chromatography.
    Type: Grant
    Filed: August 20, 1999
    Date of Patent: March 6, 2001
    Assignee: Rhone-Poulenc Rorer S.A.
    Inventors: André Durand, Alain Gerbaud, Rodolphe Margraff