Abstract: A robot arm having a series of rigid links including a first rigid link and a final rigid link, the links being operatively controlled via tendon-driven joints, each tendon-driven joint comprising a motorized spool configured to rotate in either of two directions and operatively coupled, via a cable assembly having an elastic portion, to a pulley configured to move a respective rigid link thereby. A controller adapts robot arm motion in response to position and force sensing signals. A tendon-driven joint may be implemented via one motor controlling the tension of two cables acting in opposing directions and coupled between respective ones of a pair of common-driven spools and a pair of pulleys.

Abstract: A method for forming a scaffold for use in fabricating a soft tissue implant, comprising: receiving, by a processor, soft tissue data corresponding to dimensions for a soft tissue, and a first and second weighting factor selected based on the dimensions of the soft tissue; transforming, by the processor, the soft tissue data, based on the first and second weighting factors, into a plurality of pin coordinates in a multi-dimensional space defining a shape of the scaffold for use in fabricating the soft tissue implant; and providing, by the processor, instructions to form the scaffold using weaving operations based on the pin coordinates.

Abstract: An injectable formulation for a sustained-release of a local anesthetic is provided. The formulation comprises a pharmaceutically effective amount of a local anesthetic encapsulated into polymeric particles having a diameter from about 1 ?m to about 4 ?m. Such formulation prolongs analgesic effect, decreases toxicity, and allows loading larger doses, and at the same time is injectable directly at a patient's body site of the interest without generating a surgical wound. Methods of use and preparation are also provided.

Abstract: An electronic-sensing & magnetic-modulation (ESMM) biosensor device and methods of using the same, where the device incorporates electrical, microfluidic, and magnetic subsystems. The device and methods of using such a device can be applied to high throughput point-of-care screening for the quantification and evaluation of a subject's immune response to pathogenic infections, which can be useful for: early diagnosis, stratifying high-risk subjects infected with a pathogen; and determining the status or effectiveness of a therapeutic response.

Abstract: The present disclosure relates, in part, to a method for preparing a carbon nanomaterial from a plastic material. In certain embodiments, the method comprises nonsolvent induced phase separation of the plastic material to provide plastic nanoparticles. In certain embodiments, the method comprises hydrothermal conversion of the plastic nanoparticles to carbon nanomaterials. In certain embodiments, the plastic material is derived from waste material. In certain embodiments, the plastic material is polypropylene (PP). In certain embodiments, the carbon nanomaterial is carbon dots (CDs). In another aspect, the disclosure provides a method for altering the properties of CDs by post-processing to afford graphitic materials.

Abstract: A tiltable near-vertical bifacial (TNVBF) solar panel assembly comprising one or more BF solar panels configured to be positioned in a first (AM) tilt position to improve energy conversion of morning sunlight incident upon a first side of the one or more BF solar panels, and to be positioned in a second (PM) tilt position to improve energy conversion of afternoon sunlight incident upon a second side of the one or more BF solar panels.

Abstract: The present disclosure relates to a new modular approach for the generation of genetically modified cells, particularly immune cells and iPSCs, enabling the simultaneous precise editing of defined nucleic acid targets (knock-out) and the introduction of an exogenous sequence of choice at a desired locus (knock-in) using a common Cas9 element.

Abstract: Sensors employing elastomers enhanced with electrically conductive 2D nanoparticles are provided. The nanoparticles are formed by applying shear to layered materials present in elastomer precursors (e.g., elastomeric monomer(s) and/or curing agent(s)). Subsequent exfoliation of the layers occurs directly within the precursor and/or curing agent. The cured elastomer nanocomposites can be employed for electrochemical sensing, flexible touchpads, pressure sensors, and wireless sensors, amongst other applications.

Abstract: The present disclosure provides compounds which are useful for a number of catalytic transformations of organic molecules, non-limiting examples including dehydrogenation of alkanes. The present disclosure further relates to methods of preparing the compounds of the present disclosure.

Abstract: The present invention discloses a system for targeted gene editing and related uses.

Abstract: Disclosed herein are compounds useful for treating obstructive lung diseases. The compounds are TAS2Rs agonists and may further be used to treat disorders and conditions implicated by TAS2R. In some instances the disclosed compounds can be used to treat asthma.

Abstract: Endophytic bacteria, compositions comprising the same, and methods of use thereof are disclosed which increase the root and shoot growth of grass hosts, suppress growth of soil borne fungal pathogens of host plants, increase resistance of the grass to diseases and reduce competitiveness of distantly related competitor weeds of the crop.

Abstract: A device for catheterization includes a catheter sheath support mounted to a catheterization device and holding a catheter sheath, a carriage supporting a guide needle, and a connector to removably engage the catheter sheath support to the carriage. The carriage translates along an axis of insertion of the guide needle independent of the catheter sheath support when disengaged from the connector. An actuator controls separation of the carriage from the catheter sheath support at a uniform velocity in response to disengagement of the connector. Translation and separation may be automated. In response to detection of the vessel wall puncture, the carriage automatically releases from the catheter sheath support and retracts along the axis of insertion at the uniform velocity relative to the catheter sheath support, and the catheter sheath automatically advances into the target vessel along the axis of insertion at the uniform velocity while the carriage retracts.

Abstract: Various embodiments comprise systems, methods, architectures, mechanisms and apparatus providing secure physical layer (PHY) transmission via metamaterial (MTM) leaky-wave antennas (LWAs) using directed modulation (DM) transmitters such as for orthogonal frequency-division multiplexing (OFDM) and non-contiguous (NC) OFDM transmissions, where the DM functionalities exploit the property of time-modulated arrays (TMAs) realized in 1-D and 2-D spaces through the MTM-LWAs.

Abstract: This disclosure relates to assays and reagents for the detection of drug-resistance mutations in Mycobacterium. tuberculosis or of multidrug-resistant Mycobacterium tuberculosis.

Abstract: Various embodiments comprise systems, methods, architectures, mechanisms and apparatus for optical, radio frequency (RF), and/or acoustic data transmission by dividing each of one or more sequences of channel coded bits d into N blocks thereof, which are respectively spatially modulated (SM) with respective pilot sequences and mapped to constellations to provide thereby respective symbol streams, which are modulated in accordance with orthogonal signal division multiplexing (OSDM) to provide respective SM-OSDM signals, which are transmitted via optical sources, RF antennae, acoustic transducers, and the like during respective timeslots such that a receiver associated with a plurality of receiving devices may reconstruct the bitstream used to form the one or more sequences of channel coded bits d.

Abstract: Computer vision systems and methods for acceleration of high-resolution mobile deep vision with content-aware parallel offloading are provided. The system allows for acceleration of deep vision applications running on mobile devices via offloading of machine learning computations on edge cloud infrastructure, and speeds up computation via parallel processing on the edge cloud, employing one or more of the following processes: recurrent region proposal prediction, region proposal centric frame partitioning, and resource-aware offloading to multiple processors. Mobile deep vision applications can utilize the systems and methods disclosed herein to accelerate application processing. The system offloads computation to multiple servers to minimize the end-to-end latency, and includes a high-resolution mobile deep vision task acceleration system that offloads computation to multiple (edge located) servers.

Abstract: The present invention relates to novel primers and sloppy molecular beacon and molecular beacon probes for amplifying segments from different genes in Mycobacterium tuberculosis for identifying the presence of M.tb DNA and/or resistance to anti-tuberculosis drugs.

Abstract: This disclosure provides a microfluidic system (e.g., microfluidic cartridge, microfluidic chip) comprising two or more microfluidic flow channels for impedance-based detection of a biological entity in a sample. The disclosed system enables simultaneous measurements of a sample in two or more microfluidic flow channels to minimize faulty results. It eliminates the need of lysing samples and measuring them multiple times that is more time-consuming, and could introduce some variations across samples and devices.

Abstract: A cellularized nerve regeneration graft is disclosed that includes an electrospun biodegradable polymer conduit having an exterior surface and an interior luminal space, a plurality of fibroblasts seeded to the exterior surface of the conduit, and a system filling the interior luminal space of the conduit. The system may include a hydrogel matrix or augmented hydrogel matrix and Schwann cells. The cellularized nerve regeneration graft may be used in the repair of peripheral nerve injuries. Methods of making the cellularized nerve regeneration graft are also disclosed.