Abstract: Methods and apparatus are provided for treating hypertension, e.g., via a pulsed electric field, via a stimulation electric field, via localized drug delivery, via high frequency ultrasound, via thermal techniques, etc. Such neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, neuromodulation is applied to neural fibers that contribute to renal function. In some embodiments, such neuromodulation is performed in a bilateral fashion. Bilateral renal neuromodulation may provide enhanced therapeutic effect in some patients as compared to renal neuromodulation performed unilaterally, i.e., as compared to renal neuromodulation performed on neural tissue innervating a single kidney.

Abstract: A digital-to-analog converter (DAC) may include a conversion block providing a first analog value. The DAC may also include an amplification block for receiving the first analog value and providing a second analog value amplified by an amplification factor. The amplification block may include a first input terminal for receiving the first analog value, a second input terminal, and an output terminal for providing the second analog value. The amplification block may also include a first capacitive element and a second capacitive element. The first and second capacitive elements may determine the amplification factor. The amplification block may further include a control unit for recovering a charge at a first terminal of the second capacitive element, and based thereon, the second analog value.

Abstract: A luggage article may include a plurality of walls together defining an outer structure of the luggage article, a wheel bracket attached to and extending from one of the walls, and a wheel attached to the wheel bracket. The wheel bracket may comprise first and second elongate arms extending along a common side of the wheel. The first and second arms may be vertically-spaced apart from one another over at least a portion of the length of the first and second arms. The configuration of the wheel bracket may result in higher shock absorption and reduced wheel noise comparative to conventional wheel brackets, and offer an improvement and alternative to conventional luggage wheel brackets.

Abstract: A guide rail assembly for a submersible machine as well as a guide rail holder for such a guide rail assembly is described herein. The guide rail holder includes a radially extending support body and an axially extending post, which is rigidly connected to the support body and which is adapted to be inserted into an end of the guide rail. An engagement head is connected to the post at a distance from the support body and has a greater radial extension than the post. The engagement head includes a radially expandable member that is adapted to be reversibly manipulated between an active state, in which the expandable member is in engagement with the guide rail, and an inactive state, in which the expandable member is disengaged from the guide rail.

Abstract: A push-pull amplifier includes a pair of active devices driving the primary side of a double distributed active transformer (DDAT). The primary side of the DDAT includes a cascaded arrangement of primary windings of a first set of transformers with the active devices coupled ends of cascaded arrangement of primary windings. The secondary side of the DDAT includes a cascaded arrangement of secondary windings of a second set of transformers coupled to a load. Secondary windings of the first set of transformers drive inputs of respective active stages. Outputs of the active stages drive respective primary windings of the second set of transformers.

Abstract: The present technology relates to a method of introducing a supported antistatic compound that does not comprise a transition-metal-based catalyst component for use in an olefin polymerization reactor. In some embodiments, the methods disclosed herein avoid the formation of polymer agglomerates in the reactor and minimize potentially negative effects on catalyst yield.

Abstract: A for positioning a miniaturized piece includes a positioning structure that forms a first cavity designed to receive with play the miniaturized piece and a second cavity communicating with the first cavity. At least one electrical-contact terminal is provided facing the second cavity and is electrically coupleable to an electronic testing device designed to carry out an electrical test on the miniaturized piece. An actuator device causes a vibration of the positioning structure such that the vibration translates the miniaturized piece towards the second cavity until it penetrates at least in part into the second cavity.

Abstract: A tensioner for a start-stop accessory drive comprises a movable support, a pulley carried by the support to contact a belt of the drive, a spring to load the support so as to tension the belt, and an actuator controlled and movable to push said pulley against the belt in one direction by means of a load in parallel and additional with respect to that of the spring and an irreversible device which enables the action of the actuator and prevents a displacement of said support in response to the loads of the belt.

Abstract: In order to improve the performance of a battery power supply unit for a bicycle electronic device at low atmospheric temperature, when its temperature is less than or equal to a lower temperature threshold, electrical energy is supplied by the power supply unit to a heating element thermally coupled with the power supply unit that, in this way, self-heats. Part of the electrical energy of the power supply unit can be simultaneously supplied to the electronic device.

Abstract: A voltage doubler circuit supports operation in a positive voltage boosting mode to positively boost voltage from a first node to a second node and operation in a negative voltage boosting mode to negatively boost voltage from the second node to the first node. The voltage doubler circuits receive two clock signals having different high voltage levels. A series of voltage doubler circuit are connected in a charge pump with controllable operation in the first and second modes. A connecting circuit interconnects the first and second nodes of the voltage doubler circuits to provide a first connection path, with a first input voltage, to support the positive voltage boosting mode operation and a second connection path, with a proper input voltage, to support the negative voltage boosting mode. A discharge circuit is provided to discharge the voltage doubler circuits when operation of the charge pump circuit is terminated.

Abstract: A system and method for processing the copyright notice of a media file stored in digital format in an electronic device are provided. The copyright notice of the media file is checked prior and/or during transmission between two devices and if the copyright notice is not found, action is taken to insert the copyright notice. The copyright notice is presented when the media file is presented.

Abstract: In the method of hair color consultation, actual individual images of a person are continuously recorded by a video camera and are input into a computer in a continuous sequence in real time. Automatic image editing and processing is carried out in real time, in which the computer continuously marks hair regions of the individual images by an automatic analysis of close and similar pixel color values, of contiguous texture, and/or of contiguous morphological properties, and changes hair color of the hair regions according to predetermined specifications. Then the modified individual images with the changed hair color are displayed on the at least one screen and/or touch screen in real time so that the desired hair color may be selected. An apparatus for performing the method is also described.

Abstract: Methods for therapeutic renal denervation are disclosed herein. One aspect of the present application, for example, is directed to methods that block, reduce and/or inhibit renal sympathetic nerve activity to achieve a reduction in central sympathetic tone. Renal sympathetic nerve activity may be altered or modulated along the afferent and/or efferent pathway. The achieved reduction in central sympathetic tone may carry several therapeutic benefits across many disease states.

Abstract: The device (1) for supplying micronized medical salt comprises a container (2) for medical salt, having a vertical longitudinal development and a lower end portion (3) provided with a mouth of release (4) of the medical salt, a screw (20) inserted into the container and having an upper end (21) and a lower end (22) which is free, rotation members (30) of the screw mechanically connected thereto for rotating it with respect to the container, where the screw advances the medical salt downward so that the medical salt is released in a controlled manner from the mouth of release (4), the device further comprising a dispenser (50) which comprises a supply duct (51) and a ventilation member (60) which generates an air flow within the supply duct, where the mouth of release is in communication with the supply duct so as to release the medical salt directly in the air flow.

Abstract: Dispenser device for automatic dispensing machines of carbonated beverages from bottles and like containers. At least one decompression chamber is associated and works together to an inert gas insufflating system in order to maintain the carbon dioxide content of the beverage after the bottle is opened, therefore keeping the original effervescence and perlage of the dispensed carbonated beverage up to complete depletion of the bottle.

Abstract: A signal processing chain, such as an audio chain, produces an analog output signal from a digital input signal. The signal processing chain is operated by generating a first flag signal for the analog output signal and one or more second flag signals for the digital input signal. Each flag signal assumes a first level or a second level and is set to the first level when a signal from which the flag is generated has a value within an amplitude window. An amount the first flag signal for the analog output signal and the second flag signal for the digital input signal match each other may be calculated for issuing an alert flag which indicates an impaired operation of the signal processing chain.

Abstract: The present invention relates to an antibody, recombinant or synthetic antigen-binding fragments thereof able to recognize and bind an epitope comprised in the spacer domain of ADAMTS-5, nucleic acid and expression vector encoding the same, method of production and uses thereof.

Abstract: The present invention concerns the high speed packaging of folded paper articles such as tissues, napkins and the like, and more precisely it concerns an apparatus for continuously feeding such articles, arranged in stacked groups(P, P1) coming from folding machines, towards packaging machines, for example with a rotating drum, arranged downstream.

Abstract: Automated warehouses are provided which include a main path, a series of secondary paths perpendicular to the main path along which storage stations are defined, suitable for receiving cargo units. In order to move the cargo units, a main self-propelled vehicle is movable along the main path, and is associated with an auxiliary self-propelled vehicle, movable along the secondary paths. Location data representations are provided along the paths, which identify absolute positions of reference points or ranges within the automated warehouse. Sensors to read the data are mounted on board of the main self-propelled vehicle and the auxiliary self-propelled vehicle. Methods for storing and withdrawing cargo units in automated warehouses are also provided.