Patents Assigned to Saga University
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Patent number: 10863752Abstract: A plasma sterilization apparatus includes a voltage-applying unit that applies a voltage to a sterilization target having conductivity; a pair of electrodes that apply, in a discharged state, the voltage applied by the voltage-applying unit to the sterilization target via a dielectric; and a position changing unit that changes a relative position between the pair of electrodes and the sterilization target.Type: GrantFiled: October 27, 2016Date of Patent: December 15, 2020Assignees: National Institute of Technology, Saga University, University of the RyukyusInventors: Yoshihito Yagyu, Tatsuya Misawa, Akikazu Sakudo
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Patent number: 10832410Abstract: The present invention is to provide a computer system, a method, and a program for diagnosing a subject that improve the accuracy of diagnosis by combining a plurality of time-series image data more than that by a conventional single image analysis. The computer system for diagnosing a subject acquires a plurality of first subject images with time series variation of the subject, analyzes the acquired first subject images, acquires a plurality of second subject images with time series variation of another subject in the past, analyzes the acquired second subject images, checks the analysis result of the first subject images and the analysis result of the second subject images, and diagnoses the subject based on the check result.Type: GrantFiled: May 19, 2017Date of Patent: November 10, 2020Assignees: OPTIM CORPORATION, SAGA UNIVERSITYInventors: Shunji Sugaya, Yoshio Okumura, Hiroshi Enaida, Mika Sakaguchi, Eizaburo Sueoka
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Patent number: 10814039Abstract: Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.Type: GrantFiled: January 12, 2017Date of Patent: October 27, 2020Assignees: KYOCERA CORPORATION, SAGA UNIVERSITYInventors: Masaaki Mawatari, Masatsugu Tsukamoto, Iwao Noda
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Publication number: 20200289605Abstract: An object of the present invention is to provide a composition for preventing or improving fat deposition on the liver in spite of the alcohol intake history of a level that a liver disease is not caused. The inventors found that glutathione has an effect of preventing or improving fat deposition on the liver, which is not caused by alcohol, and completed the present invention. Among nonalcoholic fat diseases, the present invention is particularly effective in an early stage of the treatment or in a case where treatment for another disease is not performed.Type: ApplicationFiled: June 1, 2020Publication date: September 17, 2020Applicants: KOHJIN LIFE SCIENCES CO., LTD., PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, SAGA UNIVERSITYInventors: Takaomi KESSOKU, Atsushi NAKAJIMA, Yoshio SUMIDA, Yuichiro EGUCHI, Susumu SAITO, Yusuke SAUCHI
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Patent number: 10460934Abstract: According to an aspect of a present inventive subject matter, a crystalline film includes a crystalline metal oxide as a major component, the crystalline film includes a corundum structure, a surface area that is 9 ?m2 or more, and a dislocation density that is less than 5×106 cm?2.Type: GrantFiled: August 21, 2018Date of Patent: October 29, 2019Assignees: FLOSFIA INC., NATIONAL INSTITUTE FOR MATERIALS SCIENCE, KYOTO UNIVERSITY, SAGA UNIVERSITYInventors: Yuichi Oshima, Shizuo Fujita, Kentaro Kaneko, Makoto Kasu, Katsuaki Kawara, Takashi Shinohe, Tokiyoshi Matsuda, Toshimi Hitora
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Publication number: 20190241681Abstract: Provided is a method of separating a catalyst of a hydrogenated nitrile rubber, the method including: a water-soluble polymer addition step of adding an aqueous solution of a water-soluble polymer to a water-soluble organic solvent solution of the hydrogenated nitrile rubber obtained by hydrogenating a nitrile rubber in the presence of a platinum group element-containing catalyst; and a water-soluble polymer precipitating step of precipitating the water-soluble polymer while incorporating the platinum group element in the water-soluble polymer by stirring the water-soluble organic solvent solution of the hydrogenated nitrile rubber to which the aqueous solution of the water-soluble polymer is added.Type: ApplicationFiled: July 12, 2017Publication date: August 8, 2019Applicants: ZEON CORPORATION, SAGA UNIVERSITYInventors: Akito NAKAI, Hidetaka KAWAKITA, Keisuke OHTO, Shintaro MORISADA
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Publication number: 20190125822Abstract: An object of the present invention is to provide a composition for preventing or improving fat deposition on the liver in spite of the alcohol intake history of a level that a liver disease is not caused. The inventors found that glutathione has an effect of preventing or improving fat deposition on the liver, which is not caused by alcohol, and completed the present invention. Among nonalcoholic fat diseases, the present invention is particularly effective in an early stage of the treatment or in a case where treatment for another disease is not performed.Type: ApplicationFiled: December 26, 2018Publication date: May 2, 2019Applicants: KOHJIN LIFE SCIENCES CO., LTD., PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, SAGA UNIVERSITYInventors: Takaomi KESSOKU, Atsushi NAKAJIMA, Yoshio SUMIDA, Yuichiro EGUCHI, Susumu SAITO, Yusuke SAUCHI
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Publication number: 20180317508Abstract: There is provided a plasma sterilization apparatus that permits plasma sterilization providing a uniform sterilization for even sterilization targets having various kinds of three-dimensional shape such as agricultural products, under mild conditions so as to prevent damage and quality deterioration of the targets. A plasma sterilization apparatus includes a voltage-applying unit that applies a voltage to a sterilization target having conductivity; a pair of electrodes that apply, in a discharged state, the voltage applied by said voltage-applying unit to the sterilization target via a dielectric; and a position changing unit that changes a relative position between the pair of electrodes and the sterilization target.Type: ApplicationFiled: October 27, 2016Publication date: November 8, 2018Applicants: NATIONAL INSTITUTE OF TECHNOLOGY, SAGA UNIVERSITY, UNIVERSITY OF THE RYUKYUSInventors: Yoshihito Yagyu, Tatsuya Misawa, Akikazu Sakudo
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Patent number: 9976968Abstract: There is provided a crack detection system in which a crack can be detected from a strain distribution of a part to be detected of an object. After taking the image of the part to be detected of the detection object by the imaging unit, the heat is applied by the heating unit. Furthermore, image of the part to be detected are taken again and an image analysis unit analyzes the images before and after applying the heat to acquire a strain distribution of the part to be detected, so that the crack can be detected based on difference in a state of strain between a place where the crack exist and the other place. Therefore, taking the images of the part to be detected including its coating layer enables the analysis to progress without removing the coating layer to detect the crack.Type: GrantFiled: October 17, 2014Date of Patent: May 22, 2018Assignees: SAGA UNIVERSITY, NAGASAKI UNIVERSITYInventors: Yukihiro Ito, Kazuhisa Shiki, Hiroshi Matsuda, Akira Demizu
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Patent number: 9945263Abstract: There is provided a steam power cycle system in which steam power cycles using pure materials as a working fluid is used in a multiple stage to reduce pressure loss in the flow channels in the respective heat exchanger so that the fluid serving as heat sources has been caused to make an effective heat exchange with the working fluid. More specifically, not only that the respective flow channels for the fluid serving as heat sources in the evaporator and the condenser in the respective steam power cycle units are connected in series to each other, but the evaporator and the condenser comprise a cross-flow type heat exchanger and are arranged respectively in a flowing direction of the fluid serving as heat source. Consequently, it is possible to reduce the length of the flow channels to the minimum necessary, simplify the flow channel structure, and reduce the pressure loss.Type: GrantFiled: March 7, 2014Date of Patent: April 17, 2018Assignee: SAGA UNIVERSITYInventors: Yasuyuki Ikegami, Sadayuki Jitsuhara, Taro Watanabe, Shin Okamura
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Publication number: 20180050078Abstract: An object of the present invention is to provide a composition for preventing or improving fat deposition on the liver in spite of the alcohol intake history of a level that a liver disease is not caused. The inventors found that glutathione has an effect of preventing or improving fat deposition on the liver, which is not caused by alcohol, and completed the present invention. Among nonalcoholic fat diseases, the present invention is particularly effective in an early stage of the treatment or in a case where treatment for another disease is not performed.Type: ApplicationFiled: March 2, 2016Publication date: February 22, 2018Applicants: KOHJIN LIFE SCIENCES CO., LTD., PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, SAGA UNIVERSITYInventors: Takaomi KESSOKU, Atsushi NAKAJIMA, Yoshio SUMIDA, Yuichiro EGUCHI, Susumu SAITO, Yusuke SAUCHI
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Patent number: 9625451Abstract: The present invention provides a method for detecting chronic sinusitis, which comprises measuring the concentration of a periostin protein in blood or nasal secretion collected from a test subject. Thereby, a method for detecting chronic sinusitis, which is capable of detecting chronic sinusitis more simply, more promptly and less invasively, is provided.Type: GrantFiled: October 30, 2012Date of Patent: April 18, 2017Assignees: SAGA UNIVERSITY, YAMAGATA UNIVERSITYInventors: Kenji Izuhara, Shoichiro Ohta, Kazuhiko Arima, Hiroshi Shiraishi, Shoichi Suzuki, Nobuo Ohta, Akihiro Ishida, Yusuke Suzuki
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Publication number: 20160340736Abstract: Provided is a lung cancer biomarker containing a DDR2 protein or a DDR2 gene, or a mutant thereof, i.e., the following (a), (b) and (c): (a) overexpressed DDR2 protein or DDR2 gene; (b) overexpressed DDR2 protein or DDR2 gene mutant; and (c) DDR2 protein or DDR2 gene mutant.Type: ApplicationFiled: December 25, 2014Publication date: November 24, 2016Applicants: SAGA UNIVERSITY, ARKRAY, INC.Inventors: Naoko Aragane, Shinya Kimura, Naomi Watanabe
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Patent number: 9482676Abstract: The present invention provides a method for detecting idiopathic interstitial pneumonia, which comprises measuring the expression level of a periostin gene or the amount of a periostin protein in a biological sample. Thereby, a method for detecting idiopathic interstitial pneumonia using a marker is provided.Type: GrantFiled: February 27, 2013Date of Patent: November 1, 2016Assignees: SAGA UNIVERSITY, KURUME UNIVERSITYInventors: Kenji Izuhara, Shoichiro Ohta, Hiroshi Shiraishi, Hisamichi Aizawa, Tomoaki Hoshino, Masaki Okamoto
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Publication number: 20160313351Abstract: The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin.Type: ApplicationFiled: April 29, 2016Publication date: October 27, 2016Applicants: SHINO-TEST CORPORATION, SAGA UNIVERSITY, KURUME UNIVERSITYInventors: Kenji IZUHARA, Shoichiro OHTA, Tomoaki HOSHINO, Yoshinori AZUMA, Junya ONO
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Patent number: 9474299Abstract: [Problem] Providing soybean including oleic acid that will exceed the heretofore developed high-oleic soybean without using gene engineering technology. [Means to Solve the Problem] The present invention provides a GmFAD2-1b gene loss of function mutation and a type of soybean that includes a GmGAD2-1b gene loss of function mutation.Type: GrantFiled: June 21, 2010Date of Patent: October 25, 2016Assignee: SAGA UNIVERSITYInventor: Toyoaki Anai
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Patent number: 9441194Abstract: A device 2 for producing a three-dimensional structural body has an accommodating plate 3 in which an accommodating recess portion 3a for accommodating a cell mass 1 is formed, a support body 4 provided with a plurality of needle-shaped bodies 6 penetrating the cell mass, a suction nozzle 19 for adsorbing/holding the cell mass, and structure 20 for moving the suction nozzle.Type: GrantFiled: June 19, 2012Date of Patent: September 13, 2016Assignees: NATIONAL UNIVERSITY CORPORATION SAGA UNIVERSITY, CYFUSE BIOMEDICAL K.K., SHIBUYA KOGYO CO., LTD.Inventors: Koichi Nakayama, Kenji Yoneda, Masahiro Sakamoto, Ichiro Koshida, Masaharu Shomura, Isao Fukamura
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Patent number: 9347954Abstract: The present invention provides a method and a reagent for measuring periostin contained in a sample with improved accuracy, a method for improving accuracy in measurement of periostin, and a method of testing for pulmonary fibrosis or interstitial pneumonia with improved accuracy. The antibody of the present invention binds to at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin or a cleavage product thereof. The method and the reagent for measuring periostin and the method for improving accuracy in periostin measurement of the present invention is characterized by detecting at least one region selected from the group consisting of an EMI region, an R1 region, an R2 region, and an R3 region of periostin.Type: GrantFiled: September 6, 2012Date of Patent: May 24, 2016Assignees: SHINO-TEST CORPORATION, SAGA UNIVERSITY, KURUME UNIVERSITYInventors: Kenji Izuhara, Shoichiro Ohta, Kazuhiko Arima, Hiroshi Shiraishi, Shoichi Suzuki, Tomoaki Hoshino, Yoshinori Azuma, Junya Ono
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Publication number: 20160135946Abstract: The present invention addresses the problem of providing an artificial skin preparation which requires no suturing or the like when treating a wound area with a dried collagen vitrigel membrane material as an artificial skin, and also is less likely to cause contamination or the like with an exudate, and is free from the risk of secondary damage by replacement thereof.Type: ApplicationFiled: June 24, 2014Publication date: May 19, 2016Applicants: Saga University, National Institute of Agrobiological Sciences, Yutoku Pharmaceutical Industries Co., Ltd.Inventors: Shigehisa AOKI, Toshiaki TAKEZAWA, Ayumi MIYAZAKI, Hiroshi HIRAYAMA
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Patent number: 9327013Abstract: An activity enhancer for an anticancer agent includes, as an active ingredient, a D-form amino acid residue-containing FNIII14 polypeptide, the D-form amino acid residue-containing FNIII14 being a polypeptide FNIII14 represented by SEQ ID NO: 1 in which at least one of amino acid residues at positions 1 to 13 is a D-form amino acid residue. An anticancer composition includes the activity enhancer for an anticancer agent and an anticancer agent.Type: GrantFiled: March 9, 2012Date of Patent: May 3, 2016Assignees: TOKYO UNIVERSITY OF SCIENCE FOUNDATION, SAGA UNIVERSITY, NATIONAL UNIVERSITY CORPORATION KAGAWA UNIVERSITYInventors: Fumio Fukai, Hiroaki Kodama, Takuya Matsunaga