Patents Assigned to Salix Pharmaceuticals, Ltd
  • FORMULATIONS AND USES OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES FOR THE TREATMENT OF MALES
    Publication number: 20150132381
    Abstract: The instant application provides methods and compositions for the treatment of male subjects having ulcerative colitis.
    Type: Application
    Filed: October 8, 2014
    Publication date: May 14, 2015
    Applicant: SALIX PHARMACEUTICALS, LTD
    Inventors: William Forbes, Enoch Bortey, Lorin K. Johnson
  • FORMS OF RIFAXIMIN AND USES THEREOF
    Publication number: 20150118307
    Abstract: Embodiments relate to Rifaximin polymorphic, salt, and hydrate forms, methods of producing polymorphic forms and to their use in medicinal preparations and to therapeutic methods using them.
    Type: Application
    Filed: May 27, 2014
    Publication date: April 30, 2015
    Applicant: SALIX PHARMACEUTICALS, LTD
    Inventors: Stephan D. Parent, Lisa Lynn McQueen, Patricia Andres, Paul Schields, Yiduo Wu, Fei Ding, Jared Peters Smit
  • Rifaximin anti-rectal dysfunction preparation
    Patent number: 8987292
    Abstract: The present invention relates to compositions and methods for treating rectal disorders.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: March 24, 2015
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Alan Safdi, David Taylor
  • Methods of treating hepatic encephalopathy
    Patent number: 8969398
    Abstract: The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic is rifaximin.
    Type: Grant
    Filed: February 15, 2013
    Date of Patent: March 3, 2015
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventor: William Forbes
  • Methods and compositions for treating HIV-associated diarrhea
    Patent number: 8962680
    Abstract: Presented herein are methods for treating diarrhea by administering to a patient in need thereof, an inhibitor of chloride-ion transport in an amount sufficient to treat diarrhea. Treatment of diarrhea includes the treatment of the diarrhea as well as the pain, abdominal discomfort and other symptoms associated with diarrhea. In one embodiment, the inhibitor of chloride-ion transport is crofelemer.
    Type: Grant
    Filed: October 31, 2011
    Date of Patent: February 24, 2015
    Assignees: Salix Pharmaceuticals, Ltd., Napo Pharmaceuticals, Inc.
    Inventors: William Forbes, Enoch Bortey, Steven King, Pravin Chaturvedi
  • Methods of treating traveler's diarrhea and hepatic encephalopathy
    Patent number: 8946252
    Abstract: Treatment of traveler's diarrhea using in subjects having hepatic encephalopathy using gastrointestinal specific antibiotics is disclosed. One example of a gastrointestinal specific antibiotic is rifaximin.
    Type: Grant
    Filed: October 18, 2012
    Date of Patent: February 3, 2015
    Assignee: Salix Pharmaceuticals, Ltd
    Inventors: William Forbes, Enoch Bortey
  • Methods of treating traveler's diarrhea and hepatic encephalopathy
    Patent number: 8829017
    Abstract: Treatment of traveler's diarrhea using in subjects having hepatic encephalopathy using gastrointestinal specific antibiotics is disclosed. One example of a gastrointestinal specific antibiotic is rifaximin.
    Type: Grant
    Filed: March 31, 2011
    Date of Patent: September 9, 2014
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: William Forbes, Enoch Bortey
  • Forms of rifaximin and uses thereof
    Patent number: 8815888
    Abstract: The present invention relates to new rifaximin forms kappa, theta, rifaximin:piperazine cocrystal 1 and rifaximin:piperazine cocrystal 2, methods of making same and to their use in medicinal preparations and therapeutic methods.
    Type: Grant
    Filed: July 31, 2013
    Date of Patent: August 26, 2014
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Yiduo Wu, Stephan D. Parent, Nathan Carl Schultheiss, Melanie Janelle Bevill, Petinka Vlahova, Travis L. Houston
  • Forms of rifaximin and uses thereof
    Patent number: 8754098
    Abstract: The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them.
    Type: Grant
    Filed: August 23, 2012
    Date of Patent: June 17, 2014
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Karen S. Gushurst, Donglai Yang, Melanie Janelle Bevill, Nathan Carl Schultheiss, Petinka Vlahova, Jeffrey S. Stults, Travis L. Houston
  • Forms of rifaximin and uses thereof
    Patent number: 8735419
    Abstract: Embodiments relate to Rifaximin polymorphic, salt, and hydrate forms, methods of producing polymorphic forms and to their use in medicinal preparations and to therapeutic methods using them.
    Type: Grant
    Filed: February 10, 2012
    Date of Patent: May 27, 2014
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Stephan D. Parent, Lisa L. McQueen, Patricia Andres, Paul Schields, Yiduo Wu, Fei Ding, Jared P. Smit
  • METHOD OF STABLY TREATING INCONTINENCE USING A BULKING AGENT
    Publication number: 20140045788
    Abstract: The invention provides a method for treating fecal incontinence in a subject comprising administering in an appropriate subject a therapeutically effective amount of a biocompatible bulking agent to the wall of the anal canal. The biocompatible bulking agent comprises dextranomer and a pseudoplastic carrier, such as, hyaluronic acid, and is stable and effective in treating fecal incontinence for over 24 months, and up to at least 36 months or more following an initial administration.
    Type: Application
    Filed: October 21, 2013
    Publication date: February 13, 2014
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventor: Howard Franklin
  • Methods of treating hepatic encephalopathy
    Patent number: 8642573
    Abstract: The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic is rifaximin. The instant application also provides methods for determining if a subject has a neurological condition or hepatic encephalopathy by determining the critical flicker frequency and/or the venous ammonia level of the subject at two or more time points. The invention further provides methods for treating these subjects.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: February 4, 2014
    Assignee: Salix Pharmaceuticals, Ltd
    Inventors: William Forbes, Kunal Merchant, Enoch Bortey, Audrey Shaw
  • Forms of rifaximin and uses thereof
    Patent number: 8569326
    Abstract: The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them.
    Type: Grant
    Filed: August 16, 2012
    Date of Patent: October 29, 2013
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Karen S. Gushurst, Donglai Yang, Petinka Vlahova, Jeffrey S. Stults
  • Forms of rifaximin and uses thereof
    Patent number: 8513275
    Abstract: The present invention relates to new rifaximin forms kappa, theta, rifaximin:piperazine cocrystal 1 and rifaximin:piperazine cocrystal 2, methods of making same and to their use in medicinal preparations and therapeutic methods.
    Type: Grant
    Filed: June 3, 2011
    Date of Patent: August 20, 2013
    Assignee: Salix Pharmaceuticals, Ltd
    Inventors: Yiduo Wu, Stephan D. Parent, Nathan Carl Schultheiss, Melanie Janelle Bevill, Petinka Vlahova, Travis L. Houston
  • Forms of rifaximin and uses thereof
    Patent number: 8507517
    Abstract: Embodiments relate to Rifaximin polymorphic, salt, and hydrate forms, methods of producing polymorphic forms and to their use in medicinal preparations and to therapeutic methods using them.
    Type: Grant
    Filed: June 22, 2012
    Date of Patent: August 13, 2013
    Assignee: Salix Pharmaceuticals, Ltd
    Inventors: Stephan D. Parent, Lisa Lynn McQueen, Patricia Andres, Paul Schields, Yiduo Wu, Fei Ding, Jared Peters Smit
  • Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives for the treatment of males
    Patent number: 8497256
    Abstract: The instant application provides methods and compositions for the treatment of male subjects having ulcerative colitis.
    Type: Grant
    Filed: April 26, 2011
    Date of Patent: July 30, 2013
    Assignee: Salix Pharmaceuticals, Ltd
    Inventors: William Forbes, Enoch Bortey, Lorin Johnson
  • Forms of rifaximin and uses thereof
    Patent number: 8486956
    Abstract: The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them.
    Type: Grant
    Filed: February 19, 2010
    Date of Patent: July 16, 2013
    Assignee: Salix Pharmaceuticals, Ltd
    Inventors: Karen S. Gushurst, Donglai Yang, Petinka Vlahova, Jeffrey S. Stults
  • METHODS OF TREATING BOWEL DISEASES BY ADMINISTERING A BOWEL CLEANSER AND AN ANTIBIOTIC
    Publication number: 20130164384
    Abstract: The present invention relates to formulations and kits for the treatment of bowel disease, to their use in medicinal preparations and to therapeutic methods thereof.
    Type: Application
    Filed: September 5, 2012
    Publication date: June 27, 2013
    Applicant: Salix Pharmaceuticals, Ltd.
    Inventors: Lorin Johnson, William Forbes, Stephana Patton
  • METHODS OF TREATING HEPATIC ENCEPHALOPATHY
    Publication number: 20130123209
    Abstract: The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic is rifaximin. The instant application also provides methods for determining if a subject has a neurological condition or hepatic encephalopathy by determining the critical flicker frequency and/or the venous ammonia level of the subject at two or more time points. The invention further provides methods for treating these subjects.
    Type: Application
    Filed: January 9, 2013
    Publication date: May 16, 2013
    Applicant: Salix Pharmaceuticals, Ltd
    Inventor: Salix Pharmaceuticals, Ltd
  • Automatic injection device
    Patent number: D715422
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: October 14, 2014
    Assignees: Salix Pharmaceuticals, Ltd., Radius Product Development, Inc., Progenics Pharmaceuticals, Inc.
    Inventors: Ryan Hall, Sean Phillips, Charles Sears, Bonnie Jean Smelser, Holly Owens