Patents Assigned to Salix Pharmaceuticals, Ltd
  • FORMS OF RIFAXIMIN AND USES THEREOF
    Publication number: 20130066079
    Abstract: The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them.
    Type: Application
    Filed: August 23, 2012
    Publication date: March 14, 2013
    Applicant: Salix Pharmaceuticals, Ltd.
    Inventors: Karen S. Gushurst, Donglai Yang, Melanie Roe, Nathan Schultheiss, Petinka Vlahova, Jeffrey S. Stults, Travis L. Houston
  • FORMS OF RIFAXIMIN AND USES THEREOF
    Publication number: 20120316334
    Abstract: The present invention relates to Rifaximin polymorphic forms, to their use in medicinal preparations and to therapeutic methods using them.
    Type: Application
    Filed: August 16, 2012
    Publication date: December 13, 2012
    Applicant: SALIX PHARMACEUTICALS, LTD
    Inventors: Karen S. Gushurst, Donglai Yang, Petinka Vlahova, Jeffrey S. Stults
  • Methods for treating diarrhea-associated irritable bowel syndrome
    Patent number: 8309569
    Abstract: The present invention provides methods of treating diarrhea-associated irritable bowel syndrome (IBS-D) following rifaximin administration.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: November 13, 2012
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: William Forbes, Lorin Johnson
  • Forms of rifaximin and uses thereof
    Patent number: 8227482
    Abstract: Embodiments relate to Rifaximin polymorphic, salt, and hydrate forms, methods of producing polymorphic forms and to their use in medicinal preparations and to therapeutic methods using them.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: July 24, 2012
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Stephan D. Parent, Lisa Lynn McQueen, Patricia Andres, Paul Schields, Yiduo Wu, Fei Ding, Jared Peters Smit
  • FORMS OF RIFAXIMIN AND USES THEREOF
    Publication number: 20120108620
    Abstract: The present invention relates to new rifaximin forms kappa, theta, rifaximin:piperazine cocrystal 1 and rifaximin:piperazine cocrystal 2, methods of making same and to their use in medicinal preparations and therapeutic methods.
    Type: Application
    Filed: June 3, 2011
    Publication date: May 3, 2012
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: Yiduo Wu, Stephan D. Parent, Nathan Carl Schultheiss, Melanie Janelle Bevill, Petinka Vlahova, Travis L. Houston
  • FORMULATIONS OF RIFAXIMIN AND USES THEREOF
    Publication number: 20120077835
    Abstract: The present invention relates to new rifaximin forms comprising solid dispersions of rifaximin, methods of making same and to their use in medicinal preparations and therapeutic methods.
    Type: Application
    Filed: July 12, 2011
    Publication date: March 29, 2012
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: Jon Selbo, Jing Teng, Mohammed A. Kabir, Pam Golden
  • FORMS OF RIFAXIMIN AND USES THEREOF
    Publication number: 20120076857
    Abstract: The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them.
    Type: Application
    Filed: September 6, 2011
    Publication date: March 29, 2012
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: Karen S. Gushurst, Donglai Yang, Melanie Roe, Nathan Schultheiss, Petinka Vlahova, Jeffrey S. Stults, Travis L. Houston
  • FORMULATIONS AND USES OF 2-HYDROXY-5-PHENYLAZOBENZOIC ACID DERIVATIVES FOR THE TREATMENT OF MALES
    Publication number: 20120058184
    Abstract: The instant application provides methods and compositions for the treatment of male subjects having ulcerative colitis.
    Type: Application
    Filed: April 26, 2011
    Publication date: March 8, 2012
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: William Forbes, Enoch Bortey, Lorin Johnson
  • COMPOSITIONS FOR BOWEL PREPARATION AND METHODS OF USE THEREOF
    Publication number: 20120021064
    Abstract: The present invention relates to formulations and kits for gastrointestinal cleansing and to therapeutic methods thereof.
    Type: Application
    Filed: September 27, 2011
    Publication date: January 26, 2012
    Applicant: Salix Pharmaceuticals, Ltd.
    Inventor: Stephana Patton
  • Forms of rifaximin and uses thereof
    Patent number: 8067429
    Abstract: The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: November 29, 2011
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: Karen S. Gushurst, Donglai Yang, Melanie Roe, Nathan Schultheiss, Petinka Vlahova, Jeffrey S. Stults, Travis L. Houston
  • METHODS OF TREATING HEPATIC ENCEPHALOPATHY
    Publication number: 20110243879
    Abstract: The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic is rifaximin.
    Type: Application
    Filed: March 31, 2011
    Publication date: October 6, 2011
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventor: William Forbes
  • METHODS OF TREATING TRAVELER'S DIARRHEA AND HEPATIC ENCEPHALOPATHY
    Publication number: 20110178113
    Abstract: Treatment of traveler's diarrhea using in subjects having hepatic encephalopathy using gastrointestinal specific antibiotics is disclosed. One example of a gastrointestinal specific antibiotic is rifaximin.
    Type: Application
    Filed: March 31, 2011
    Publication date: July 21, 2011
    Applicant: Salix Pharmaceuticals, Ltd
    Inventors: William Forbes, Enoch Bortey
  • METHODS FOR TREATING BOWEL DISEASES
    Publication number: 20110118295
    Abstract: The present invention provides new methods of treating bowel disease (BD) by increasing a durability of response; treating BD in males; treating BD in adolescent subjects; treating bloating due to BD in males; and methods of maintaining remission of BD.
    Type: Application
    Filed: February 26, 2009
    Publication date: May 19, 2011
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: William Forbes, Lorin Johnson
  • FORMS OF RIFAXIMIN AND USES THEREOF
    Publication number: 20110105550
    Abstract: The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them.
    Type: Application
    Filed: August 25, 2010
    Publication date: May 5, 2011
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: Karen S. Gushurst, Dongali Yang, Melanie Roe, Nathan Schultheiss
  • Methods of treating travelers diarrhea and hepatic encephalopathy
    Patent number: 7928115
    Abstract: Treatment of traveler's diarrhea in subjects having hepatic encephalopathy using rifaximin is disclosed.
    Type: Grant
    Filed: December 1, 2010
    Date of Patent: April 19, 2011
    Assignee: Salix Pharmaceuticals, Ltd.
    Inventors: William Forbes, Enoch Bortey
  • METHODS OF TREATING HEPATIC ENCEPHALOPATHY
    Publication number: 20110071103
    Abstract: The application describes treatment of hepatic encephalopathy using gastrointestinal specific antibiotics. One example of a gastrointestinal specific antibiotic is rifaximin. The instant application also provides methods for determining if a subject has a neurological condition or hepatic encephalopathy by determining the critical flicker frequency and/or the venous ammonia level of the subject at two or more time points. The invention further provides methods for treating these subjects.
    Type: Application
    Filed: December 10, 2010
    Publication date: March 24, 2011
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: William Forbes, Kunal Merchant, Enoch Bortey, Audrey Shaw
  • METHODS OF TREATING TRAVELERS DIARRHEA AND HEPATIC ENCEPHALOPATHY
    Publication number: 20110065740
    Abstract: Treatment of traveler's diarrhea using in subjects having hepatic encephalopathy using gastrointestinal specific antibiotics is disclosed. One example of a gastrointestinal specific antibiotic is rifaximin.
    Type: Application
    Filed: December 1, 2010
    Publication date: March 17, 2011
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: William Forbes, Enoch Bortey
  • METHODS FOR TREATING IRRITABLE BOWEL SYNDROME (IBS)
    Publication number: 20110065741
    Abstract: The present invention provides new methods and kits for treating IBS; treating IBS in females; treating IBS in older subjects; and treating IBS in non-white subjects.
    Type: Application
    Filed: September 13, 2010
    Publication date: March 17, 2011
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: William Forbes, Enoch Bortey
  • NOVEL THERAPEUTIC TARGETS IN INFLAMMATORY BOWEL DISEASE
    Publication number: 20110055943
    Abstract: The present invention relates to novel sequences for use in detection, diagnosis and treatment of bowl disease (BD). The invention provides BD-associated polynucleotide sequences whose expression is associated with BD. Provided herein are diagnostic compositions and methods for the detection of BD. The present invention provides monoclonal and polyclonal antibodies specific for the BD polypeptides. The present invention also provides diagnostic tools and therapeutic compositions and methods for screening, prevention and treatment of BD.
    Type: Application
    Filed: October 16, 2008
    Publication date: March 3, 2011
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: Frank J. Gonzalez, Lorin Johnson, Xiaochao Ma
  • METHODS OF TREATING HEPATIC ENCEPHALOPATHY
    Publication number: 20110035232
    Abstract: Treatment of hepatic encephalopathy using gastrointestinal specific antibiotics is disclosed. One example of a gastrointestinal specific antibiotic is rifaximin. The instant application also provides methods for determining if a subject has a neurological condition or hepatic encephalopathy by determining the critical flicker frequency and/or the venous ammonia level of the subject at two or more time points. The further provided are methods for treating these subjects.
    Type: Application
    Filed: June 2, 2010
    Publication date: February 10, 2011
    Applicant: SALIX PHARMACEUTICALS, LTD.
    Inventors: William Forbes, Kunal Merchant, Enoch Bortey, Audrey Shaw