Patents Assigned to Samsung Life Public Welfare Foundation
  • Publication number: 20140247918
    Abstract: A mobile X-ray imaging apparatus and method of controlling the same, the mobile X-ray imaging apparatus including a movable main body, an X-ray source installed on the main body via an arm, a tilt angle and rotation angle of the arm being adjustable, a portable X-ray detector configured to detect X-rays emitted from the X-ray source, a position information acquirer configured to acquire position information indicating a position of the X-ray source relative to the portable X-ray detector, and a position controller configured to control the X-ray source to move to a position corresponding to the portable X-ray detector based on the acquired position information.
    Type: Application
    Filed: March 4, 2014
    Publication date: September 4, 2014
    Applicants: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION., SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Dong Goo KANG, Young Hun SUNG, Myung Jin CHUNG
  • Patent number: 8815581
    Abstract: The present invention relates to stem cells in which a gene that activates signaling is introduced and to a method for proliferating the stem cells. More specifically, the invention relates to a method of significantly increasing the ability of stem cells to proliferate, either by transfecting stem cells with the Notch intracellular domain (NICD) to activate the Notch signaling pathway, or by transfecting stem cells with the c-MET gene and treating the transfected stem cells with the HGF ligand protein to activate the c-MET/HGF signaling pathway. According to the present invention, as a result of activating the Notch signaling pathway or the c-MET/HGF signaling pathway, stem cells having an excellent ability to proliferate can be produced in large amounts. Particularly, since neural stem cells which have been difficult to culture in vitro can be proliferated in large amounts, thus the neural stem cells will be more useful for the preparation of cell therapeutic agents for treating cranial nerve diseases.
    Type: Grant
    Filed: February 1, 2011
    Date of Patent: August 26, 2014
    Assignee: Samsung Life Public Welfare Foundation
    Inventors: Do Hyun Nam, Seung Chyul Hong, Bong gu Kang, Kyeung Min Joo
  • Publication number: 20140213790
    Abstract: The present disclosure relates to a method for more easily and economically producing a selenophene-fused aromatic compound derivative containing various substituents and the selenophene-fused aromatic compound produced according to the method, and the selenophene-fused aromatic compound can be used for various purposes such as an intermediate of an anti-bacterial or anticancer substance, an indicator of which color is changed depending on a solvent, or a fluorescent substance.
    Type: Application
    Filed: March 28, 2014
    Publication date: July 31, 2014
    Applicants: Samsung Life Public Welfare Foundation, Industry-Academia Cooperation Group of Sejong University
    Inventors: Dongyeol Lim, Do-Hyun Nam, Rashmi Dubey, Hangeun Lee
  • Publication number: 20140119507
    Abstract: Disclosed herein are an X-ray imaging apparatus and an X-ray image generating method in which constituent materials of a target object are separated and mapped to different colors in order to provide one image which has improved distinction between tissues. The X-ray imaging apparatus includes an X-ray generator which generates X-rays and irradiates the X-rays toward a target object, an X-ray detector which acquires X-ray data which corresponds to a plurality of energy bands by detecting X-rays which have passed through the target object, and a controller which acquires a plurality of material images in which a plurality of materials constituting the target object are respectively displayed and brightness information from the X-ray data, generates one image by mapping different color channels to the plurality of material images and combining the plurality material images into a single image, and applying the brightness information to the generated image.
    Type: Application
    Filed: July 23, 2013
    Publication date: May 1, 2014
    Applicants: Samsung Life Public Welfare Foundation, Samsung Electronics Co., Ltd.
    Inventors: Hyun-Hwa OH, Kang-Eui LEE, Seo-Young CHOI, Young-Hun SUNG, Myung-Jin Chung
  • Publication number: 20140072527
    Abstract: Disclosed is a composition for the prophylaxis or therapy of intraventricular hemorrhage in preterm infants comprising mensenchymal stem cells. Functioning to prevent ventricular dilatation and reduce the level of inflammatory cytokines in cerebrospinal fluid, the composition comprising mesenchymal stem cells is advantageously useful for the prophylaxis or therapy of intraventricular hemorrhage in preterm infants. Accordingly, the composition is effectively preventive of hydrocephalus which occurs subsequent to intraventricular hemorrhage. In addition, the composition makes not only a histological and biochemical recuperation in the intraventricular hemorrhage-injured brain, but also significantly improves sensory motor functions. Mesenchymal stem cells can be used as an effective therapeutic agent because they are less prone to induce immune rejection responses and are highly likely to secrete proliferative, differentiative, and regulatory factors.
    Type: Application
    Filed: October 18, 2012
    Publication date: March 13, 2014
    Applicant: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
    Inventors: Yun Sil CHANG, Won Soon PARK
  • Publication number: 20140064444
    Abstract: The X-ray imaging device includes an X-ray generator to generate an X-ray and radiate the X-ray to an object, an X-ray detector to detect the X-ray passing through the object and acquire an image signal of the object, and a controller to analyze the image signal of the object, evaluate a characteristic of the object and generate at least one of a single energy X-ray image and a multiple energy X-ray image according to the evaluated characteristic.
    Type: Application
    Filed: September 4, 2013
    Publication date: March 6, 2014
    Applicants: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION, SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Hyun Hwa OH, Young Hun SUNG, Kang Eui LEE, Myung Jin CHUNG
  • Publication number: 20140012021
    Abstract: The present disclosure relates to a novel method for preparing selenyl-substituted aromatic aldehyde compounds by forming a selenolate nucleophile and performing a nucleophilic substitution reaction between the selenolate nucleophile and an aromatic aldehyde starting material.
    Type: Application
    Filed: July 6, 2012
    Publication date: January 9, 2014
    Applicants: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION, SEJONG UNIVERSITY INDUSTRY ACADAMY COOPERATION FOUNDATION
    Inventors: Dongyeol Lim, Do-Hyun Nam, Rashmi Dubey
  • Publication number: 20130337449
    Abstract: The present invention relates to a marker for predicting a gastric cancer prognosis, a composition and a kit for predicting gastric cancer prognosis comprising an agent for measuring the expression level thereof, and a method for predicting gastric cancer prognosis using the marker. According to the present invention, gastric cancer prognosis may be predicted promptly and accurately, and an appropriate treatment plan can be determined based on the predicted prognosis, which has an advantage of contributing to significant reduction of death caused by gastric cancer. Particularly, according to the present invention, the survival rate can be remarkably increased by using the treatment method for a stage III gastric cancer patient to a patient who has been predicted to have a negative prognosis among stage Ib/II gastric cancer patients.
    Type: Application
    Filed: December 13, 2011
    Publication date: December 19, 2013
    Applicant: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
    Inventors: Soon Myung Paik, Sung Kim, Won Ki Kang, Jee Yun Lee, Jae Moon Bae, Tae Sung Sohn, Jae Hyung Noh, Min Gew Choi, Young Suk Park, Joon Oh Park, Se Hoon Park, Ho Yeong Lim, Sin Ho Jung
  • Publication number: 20130149695
    Abstract: The present invention provides a method for detecting a gene mutation, comprising the step of performing PCR using generic PCR primers together with a blocking primer which competes with the generic primers and was modified at one end, and a method of diagnosing gene mutation-related diseases using the same. According to the invention, detection sensitivity and specificity can be increased by blocking the amplification of normal DNA and selectively amplifying mutant DNA.
    Type: Application
    Filed: December 30, 2010
    Publication date: June 13, 2013
    Applicant: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
    Inventors: Seung-Tae Lee, Chang-Seok Ki, Jong-Won Kim
  • Publication number: 20120303015
    Abstract: An electrode needle includes an electrode needle body, a metal tube, and an outer insulating tube. The electrode needle body is connected to a positive electrode of an RF generator. The metal tube is fixed around the electrode needle body and insulated from the electrode needle body. The metal tube is connected to a negative electrode of the RF generator. The outer insulating tube surrounds an upper part of the metal tube to expose a lower part of the metal tube. The outer insulating tube is movable longitudinally along the electrode needle body to vary an exposed area of the metal tube. At least one of a position, an area, and a cauterization speed of a site to be cauterized is controlled by varying the exposed area of the metal tube.
    Type: Application
    Filed: January 24, 2011
    Publication date: November 29, 2012
    Applicants: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION, TAEWOONG MEDICAL CO., LTD.
    Inventors: Kyung-Min Shin, Min-Woo Lee, Hyun-Chul Rhim
  • Publication number: 20120295348
    Abstract: The present invention relates to stem cells in which a gene that activates signaling is introduced and to a method for proliferating the stem cells. More specifically, the invention relates to a method of significantly increasing the ability of stem cells to proliferate, either by transfecting stem cells with the Notch intracellular domain (NICD) to activate the Notch signaling pathway, or by transfecting stem cells with the c-MET gene and treating the transfected stem cells with the HGF ligand protein to activate the c-MET/HGF signaling pathway. According to the present invention, as a result of activating the Notch signaling pathway or the c-MET/HGF signaling pathway, stem cells having an excellent ability to proliferate can be produced in large amounts. Particularly, since neural stem cells which have been difficult to culture in vitro can be proliferated in large amounts, thus the neural stem cells will be more useful for the preparation of cell therapeutic agents for treating cranial nerve diseases.
    Type: Application
    Filed: February 1, 2011
    Publication date: November 22, 2012
    Applicant: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
    Inventors: Do Hyun Nam, Seung Chyul Hong, Bong gu Kang, Kyeung Min Joo
  • Publication number: 20120275565
    Abstract: A radiation signal detection apparatus includes a filter unit configured to allow penetration of a component of radiation that passed through a subject, the filter unit including one or more unit filters configured to allow penetration of only a component in a predetermined energy band of the radiation, and a sensor unit, including one or more first unit sensors configured to convert only the component of the radiation for which the penetration is allowed by the unit filters into a first electric signal, one or more second unit sensors configured to convert a component in all energy bands of the radiation into a second electric signal, and a radiation signal detector configured to detect a first radiation signal and a second radiation signal by respectively using the first electric signal of the first unit sensors and the second electric signal of the second unit sensors.
    Type: Application
    Filed: April 27, 2012
    Publication date: November 1, 2012
    Applicants: SAMSUNG LIFE PUBLIC WELFARE FOUNDATION, SAMSUNG MEDICAL CENTER, SAMSUNG ELECTRONICS CO., LTD.
    Inventors: Sung-su Kim, Myung-jin Chung, Hyun-hwa Oh, Young-hun Sung, Sang-wook Han, Jae-hyun Kwon, Seok-min Han, Dong-goo Kang, Kang-eui Lee
  • Publication number: 20120108495
    Abstract: A method of inhibiting smooth muscle cell proliferation comprising administering to a subject a pharmaceutical composition including reconstituted HDL as an active ingredient.
    Type: Application
    Filed: October 25, 2011
    Publication date: May 3, 2012
    Applicants: GREEN CROSS CORPORATION, SAMSUNG LIFE PUBLIC WELFARE FOUNDATION
    Inventors: Jeong Euy PARK, Bok Soo LEE, Ki Yong KIM
  • Publication number: 20090197845
    Abstract: Disclosed is a method for treating olfactory disorders, which comprises administering to a patient a therapeutically effective amount of 3-?-hydroxymethylglutarate CoA (HMG-CoA) reductase, which has excellent effects of protecting and regenerating olfactory nerve.
    Type: Application
    Filed: April 8, 2009
    Publication date: August 6, 2009
    Applicant: Samsung Life Public Welfare Foundation Samsung Medical Center
    Inventors: Hyo-Yul Kim, Hun-Jong Dhong, Seung-Kyu Chung, Kon Chu
  • Publication number: 20080125405
    Abstract: Disclosed is a composition for treating olfactory disorders, the composition comprising at least one statin-like drug, which is an HMG-CoA reductase inhibitor, as an active ingredient. The composition has excellent effects of protecting and regenerating olfactory nerve.
    Type: Application
    Filed: June 28, 2007
    Publication date: May 29, 2008
    Applicant: Samsung Life Public Welfare Foundation Samsung Medical Center
    Inventors: Hyo-Yul Kim, Hun-Jong Dhong, Seung-Kyu Chung, Kon Chu
  • Patent number: 7320804
    Abstract: The present invention relates to a cough depressant composition containing iron for angiotensin-converting enzyme inhibitor inducing cough. The cough depressant composition of the present invention comprises 0.01-100% by weight of Fe2+(ferrous) or Fe3+(ferric). Furthermore, the cough depressant composition of the present invention can comprise an angiotensin-converting enzyme inhibitor. The cough depressant composition of the present invention relieves the pain of the patient by reducing continuous dry cough.
    Type: Grant
    Filed: November 29, 2005
    Date of Patent: January 22, 2008
    Assignee: Samsung Life Public Welfare Foundation Samsund Medical Center
    Inventors: Kyung-Pyo Hong, Seung-Woo Park, Sang-Chol Lee
  • Patent number: 7300454
    Abstract: A catheter apparatus for percutaneous coronary intervention (PCI) capable of accurately positioning the balloon and stent in a desired position includes an introducer set fixed to an opening of the human artery, a guiding catheter secured to the introducer set and introduced into the artery, a Y-connector coupled with the guiding catheter, a guidewire introduced into the guiding catheter, a balloon catheter introduced into the guiding catheter and having a balloon at the distal end thereof, a minute adjustment portion having a nut and a bolt for minutely adjusting the insertion portion of the balloon catheter in the artery, a combining frame having two legs eachcoupled with the main tube and the nut, respectively, and a clamping portion for holding the balloon catheter firmly in position.
    Type: Grant
    Filed: July 4, 2003
    Date of Patent: November 27, 2007
    Assignee: Samsung Life Public Welfare Foundation
    Inventors: Jeong Euy Park, Hyuk Nam Kwon
  • Publication number: 20070178073
    Abstract: The present invention relates to a composition comprising separated or proliferated cells from umbilical cord blood for treating developmental and/or chronic lung disease, more precisely a composition containing separated or proliferated cells from umbilical cord blood for intratracheal administration for treating developmental and/or chronic lung disease. The cells of the composition of the present invention have excellent activities of proliferation and differentiation, so that the extraction, separation and selection of a tissue donor are all very easy. Besides, the composition of the invention can be very effectively used for the treatment of developmental and/or chronic diseases by intratracheal administration.
    Type: Application
    Filed: June 22, 2006
    Publication date: August 2, 2007
    Applicants: Samsung Life Public Welfare Foundation, Medipost Co., Ltd.
    Inventors: Yun Sil Chang, Won Soon Park, Yoon-Sun Yang