Patents Assigned to Sangart, Inc.
  • Methods and compositions for oxygen transport comprising modified hemoglobin in plasma
    Patent number: 7271145
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified hemoglobin in plasma.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: September 18, 2007
    Assignee: Sangart, Inc.
    Inventors: Robert M. Winslow, Kim D. Vandegriff
  • Methods and compositions for oxygen transport comprising a method for making a high oxygen affinity modified hemoglobin
    Publication number: 20070167352
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified oxygenated hemoglobin having a high affinity for oxygen and methods for making such compositions. Such compositions according to the present invention have better stability to autooxidation and superior oxygen carrying characteristics.
    Type: Application
    Filed: March 13, 2007
    Publication date: July 19, 2007
    Applicant: Sangart, Inc.
    Inventors: Robert Winslow, Kim Vandegriff
  • Compositions and methods for delivering carbon monoxide (CO) and nitric oxide (NO) to tissue using heme proteins as carriers
    Publication number: 20060234915
    Abstract: The present invention relates to compositions and methods for delivering nitric oxide (NO) or carbon monoxide (CO) to cells using heme proteins as carriers.
    Type: Application
    Filed: March 7, 2006
    Publication date: October 19, 2006
    Applicant: Sangart, Inc.
    Inventor: Robert Winslow
  • Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
    Patent number: 6974795
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified oxygenated hemoglobin having a high affinity for oxygen and methods for making such compositions. Such compositions according to the present invention have better stability to autooxidation and superior oxygen carrying characteristics.
    Type: Grant
    Filed: August 24, 2004
    Date of Patent: December 13, 2005
    Assignee: Sangart, Inc.
    Inventors: Robert M. Winslow, Kim D. Vandegriff
  • Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin
    Publication number: 20050164915
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified oxygenated hemoglobin having a high affinity for oxygen and methods for making such compositions. Such compositions according to the present invention have better stability to autooxidation and superior oxygen carrying characteristics.
    Type: Application
    Filed: March 23, 2005
    Publication date: July 28, 2005
    Applicant: Sangart, Inc.
    Inventors: Robert Winslow, Kim Vandegriff
  • Methods for oxygen transport comprising a high oxygen affinity modified hemoglobin
    Patent number: 6844317
    Abstract: The present invention relates to blood products, and more particularly to compositions comprising a modified oxygenated hemoglobin having a high affinity for oxygen and methods for making such compositions. Such compositions according to the present invention have better stability to autooxidation and superior oxygen carrying characteristics.
    Type: Grant
    Filed: January 10, 2003
    Date of Patent: January 18, 2005
    Assignee: Sangart, Inc.
    Inventors: Robert M. Winslow, Kim D. Vandegriff
  • Method for production of stroma-free hemoglobin
    Patent number: 6773613
    Abstract: The invention relates to a system and a method of using an automated blood cell separator to prepare a high-quality hemoglobin solution as the raw material for manufacture of hemoglobin-based therapeutic oxygen carriers, so-called “blood substitutes”. The method of isolating stroma-free hemoglobin comprises the steps of: separating the red blood cells from the starting solution; washing the red blood cells in wash solution; contacting the red blood cells with a hypotonic solution to produce stromata and a hemolysate containing hemoglobin having an ionic strength and separating the hemolysate from the stromata. Further, the invention relates to a method for preparing a chemically modified hemoglobin solution.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: August 10, 2004
    Assignee: Sangart, Inc.
    Inventors: Robert M. Winslow, Kim D. Vandegriff