Patents Assigned to Sanofi
  • Patent number: 11118943
    Abstract: A sensor device is removably attachable to a drug delivery device. The sensor device comprises an array of optical sensors arranged within the sensor device such that, when the sensor device is attached to the drug delivery device, which has a first movable element configured to move along a path parallel to the longitudinal axis of the drug delivery device, each optical sensor is operable to detect light received at different locations along the path and to output a signal indicative of an amount of detected light. Circuitry is configured to receive the signals output from the optical sensors and, based on the received signals, determine information associated with a location along the path of the first movable element.
    Type: Grant
    Filed: February 10, 2020
    Date of Patent: September 14, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Matthew Jones, Samuel Steel, Barry Yates, Anthony Paul Morris
  • Patent number: 11116832
    Abstract: The present invention provides, among other things, modified recombinant HA polypeptides with broadened immunogenic profile that extends coverage to antigenically distinct influenza strains and methods of making and using the same.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: September 14, 2021
    Assignee: SANOFI PASTEUR INC.
    Inventors: Tod Strugnell, Eliud Oloo, Raymond Oomen
  • Patent number: 11116906
    Abstract: The invention relates to an arrangement for detecting a position of a plunger (4) relative to a bung (3) in a drug cartridge (1), comprising a proximity sensor (5) located close to a distal end (6) of the plunger (4) facing the bung (3) and aligned to receive light reflected by the bung (3).
    Type: Grant
    Filed: December 26, 2019
    Date of Patent: September 14, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Paul Richard Draper, Anthony Paul Morris, Stephen Francis Gilmore
  • Patent number: 11110228
    Abstract: A component for an injection device is a combined needle shield and cap component that comprises a unitary compressible body moulded from rubber. The unitary compressible body has formed therein a cavity for shielding a needle, the cavity having an opening at a first end of the component and extending axially within the component. It also has formed thereon a grip arrangement comprising one or more shape features that permit gripping by a user of the component so as to facilitate the application of force by the user along the longitudinal axis of the component. The combined needle shield and cap component has a proximal end configured to be partly insertable into a body of an injection device.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: September 7, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stephan Riedel, Peter Scharf
  • Patent number: 11103632
    Abstract: A packaging assembly includes a case configured to at least partially contain injection devices for delivering a medicament; a light sensor configured to detect light incident on the packaging assembly; and a status indicator configured to generate an output which indicates a status of the packaging assembly conditional on an intensity of light detected by the light sensor exceeding a threshold light intensity.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: August 31, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Hardy Kietzmann, Fred Luck, Stefan Riebel
  • Patent number: 11103648
    Abstract: An injector for delivering a liquid medicament is provided. The injector comprises: a housing having an opening at a first end and a cartridge contained within the housing, wherein the cartridge comprises a first fitting mechanism which is directed outwards from the opening of the housing; a removable cap; and a needle assembly supported on the removable cap, wherein the needle assembly has a second fitting mechanism which is directed outwards from a distal end of the removable cap, the removable cap being further configured such that each of the distal end and the proximal end of the removable cap are engageable with the opening of the housing, wherein the first fitting mechanism is complementary with the second fitting mechanism such that the needle assembly is connectable to the cartridge by joining the first and second fitting mechanisms.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: August 31, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Uwe Dasbach
  • Patent number: 11103633
    Abstract: A packaging assembly includes a case configured to hold at least one injection device for delivering a medicament and a mounting attachment configured to be attached to the case. The case includes one or more magnets for attaching the mounting attachment to the case and an external face of the case is formed having a recess configured to receive at least part of the mounting attachment.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: August 31, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Hardy Kietzmann, Fred Luck, Stefan Riebel
  • Patent number: 11103650
    Abstract: An auto-injector device comprises a cap removal mechanism which comprises a retractable component which is slidably mounted within a housing of the device, and a cap-removal actuator to push the retractable component out of the housing to remove a cap from the device; a dispense mechanism which comprises a driving element to expel a medicament from the device; and a dispense button which activates the cap removal mechanism when pressed a first time, engages with the dispense mechanism when released, and activates the dispense mechanism when pressed a second time. The dispense mechanism comprises an engaging element configured to engage with the dispense button when the dispense button has been pressed for a first time and released.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: August 31, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Michael Harms
  • Patent number: 11103649
    Abstract: The disclosure further relates to an autoinjector and a method of assembling the autoinjector. A syringe carrier is disclosed comprising a housing adapted to receive a syringe. They syringe includes a needle encapsulated by a removable protective needle sheath. The syringe carrier further includes two or more flexible arms protruding outwards in a relaxed state and adapted to couple with the syringe in a mounted position. In the mounted position, the flexible arms deflect radially inwards due, in part, to an axial force operating on the syringe carrier.
    Type: Grant
    Filed: June 2, 2016
    Date of Patent: August 31, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Thomas Mark Kemp, Carsten Mosebach
  • Patent number: 11097064
    Abstract: The present disclosure relates to a medicament delivery device including a cartridge holder to which an injection needle holder can be fixed, the injection needle holder holding an injection needle having a proximal end and a distal end, the proximal end being protected by an inner injection needle cap detachably connected to the injection needle holder, the cartridge holder being mounted in a housing and configured to receive a cartridge of medicament, a cap assembly detachably connected to the housing, and a gripping mechanism configured to remove the inner injection needle cap from the injection needle holder when the cap assembly is pulled away from the cartridge holder.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: August 24, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Marc Schader, Michael Helmer, Winfried Huthmacher
  • Patent number: 11098102
    Abstract: The present invention relates to a conjugate comprising a sulfonamide of formula (I) and an active pharmaceutical ingredient such as an insulin analog comprising at least one mutation relative to the parent insulin, wherein the insulin analog comprises a mutation at position B16 which is substituted with a hydrophobic amino acid and/or a mutation at position B25 which is substituted with a hydrophobic amino acid. The present invention further relates to a sulfonamide of formula (A). Moreover, the present invention relates to an insulin analog comprising at least one mutation relative to the parent insulin.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: August 24, 2021
    Assignee: SANOFI
    Inventors: Maria Mendez Perez, Nils Rackelmann, Laurent Bialy, Stefan Guessregen, Martin Will, Thomas Boehme, Ana Villar Garea, Marcus Hermann Korn, Melissa Besenius, Jens Riedel, Ulrich Werner, Michael Podeschwa
  • Publication number: 20210254156
    Abstract: The present invention relates to metformin for use in treating a patient, wherein the patient exhibits an increased level of GDF15 in response to metformin treatment; to methods of identifying a patient who will benefit or who will not benefit from metformin treatment; methods of treating a patient at risk of developing or suffering from a disease or disorder comprising administering therapeutically effective amount of metformin; methods of adapting the dosage of metformin; the usage of GDF15 as biomarker for identifying a patient who will benefit or who will not benefit from metformin treatment, kits for use in identifying a patient who will benefit from metformin treatment and the use of the kits, as well as methods of treating a patient or who will not benefit from metformin treatment.
    Type: Application
    Filed: March 11, 2021
    Publication date: August 19, 2021
    Applicants: Sanofi-Aventis Deutschland GmbH, McMaster University
    Inventors: Sibylle HESS, Thorsten SADOWSKI, Hertzel GERSTEIN, Guillaume PARE, Gregory STEINBERG
  • Patent number: 11090364
    Abstract: The invention describes novel conjugates of formula (I) of a pharmaceutical agent and a moiety capable of binding to a glucose sensing protein allowing a reversible release of the pharmaceutical agent depending on the glucose concentration.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: August 17, 2021
    Assignee: Sanofi
    Inventors: Stefan Petry, Oliver Plettenburg, Norbert Tennagels, Ulrich Werner
  • Patent number: 11090435
    Abstract: A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.
    Type: Grant
    Filed: October 10, 2019
    Date of Patent: August 17, 2021
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Shane Alistair Day, Daniel Thomas De Sausmarez Lintell, Steven Wimpenny, Christopher Jones, Aidan Michael O'Hare, Barry Yates, Robert Frederick Veasey, Christopher James Smith, Malcolm Boyd, David Martin Leak, Carmen Patricia Keating, David Sanders, Elizabeth Anne Marshall
  • Patent number: 11090436
    Abstract: The present disclosure is generally directed to a drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing and at least two separate component parts, wherein for example at least one of these component parts performs a movement relative to the housing during dose setting and for example at least one of these component parts performs a movement relative to the housing during dose dispensing, and wherein the relative movement of the at least two separate component parts with respect to each other during dose setting differs from the relative movement of the at least two separate component parts with respect to each other during dose dispensing.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: August 17, 2021
    Assignee: Sanofi
    Inventors: Richard James Vincent Avery, Matthew Meredith Jones, William Marsh, Anthony Paul Morris, David Aubrey Plumptre, Samuel Keir Steel, Robert Frederick Veasey
  • Patent number: 11083849
    Abstract: An auto-injector for delivering a liquid medicament comprising: a housing arranged to contain a syringe and a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end intended to be applied against an injection site, wherein the syringe comprises: a plurality of plunger elements arranged along a length of the syringe between the proximal end of the housing and the piston, each of the plurality of plunger elements having a longitudinal axis; and a cord arranged to connect the plurality of plunger elements, wherein the plunger elements are configured to become aligned along their axes to push the piston towards the distal end to displace the medicament when the cord is acted on by a driving force.
    Type: Grant
    Filed: November 21, 2016
    Date of Patent: August 10, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Michael Harms
  • Patent number: 11077257
    Abstract: An autoinjector includes a case, a needle shroud telescopically coupled to the case, a carrier slidably arranged in the case, a collar rotatably and slidably disposed in the case and coupled to the needle shroud and the carrier, and a trigger button operably coupled to the carrier. The case includes a rib. The needle shroud is movable between a first extended position, a retracted position, and a locked second extended position. The carrier is adapted to hold a medicament container and movable from a first axial position to a second axial position relative to the case. The carrier abuts the rib in the first axial position and the needle shroud is in the first extended position and disengages the rib when the needle shroud is in the retracted position and the trigger button is pressed to advance the carrier to the second axial position.
    Type: Grant
    Filed: March 15, 2019
    Date of Patent: August 3, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Thomas Kemp
  • Patent number: 11078160
    Abstract: The present disclosure relates to compounds of formula (I) or a pharmaceutically acceptable salt thereof wherein R1 means a fluorine atom or a perhalogeno linear alkyl radical containing 1, 2 or 3 carbon atoms; R2 means a chlorine atom, a linear alkyl radical containing 1, 2 or 3 carbon atoms or a perhalogeno linear alkyl radical containing 1, 2 or 3 carbon atoms, and R means a hydrogen atom or a radical of formula (Ia). The present disclosure also relates to processes for their preparation as well their therapeutic uses, in particular such as for use in the treatment of malaria.
    Type: Grant
    Filed: July 4, 2018
    Date of Patent: August 3, 2021
    Assignee: SANOFI
    Inventors: Cécile Pascal, Alain Pellet, Gilles Courtemanche, Simon Campbell
  • Patent number: 11077021
    Abstract: The disclosure provides a two-chamber carpule comprising two-chambers adapted to be joined together. Each chamber is adapted to contain a medicament component. The carpule further comprises a bevel arranged on a circumference of at least one of the chambers in a transition area. The bevel extends from one chamber to the other chamber.
    Type: Grant
    Filed: February 9, 2017
    Date of Patent: August 3, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Bernd Kühn, Jörn Möckel, Werner Seiferlein
  • Patent number: D926968
    Type: Grant
    Filed: June 3, 2019
    Date of Patent: August 3, 2021
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Daniel Kern, Udo Stauder, Marc Holtwick, Steffen Raab