Patents Assigned to Sanofi
  • Patent number: 10293119
    Abstract: The technical problem of the present invention to provide a medical device, which exhibits an increased safety of the device and facilitates a safe use is solved by medical device for delivering at least one drug agent, comprising a sensor, a control unit and an attachable dispense assembly, wherein the sensor is configured to detect attachment of the dispense assembly to the medical device, wherein the control unit is configured to determine at least based on a signal from the sensor whether the end of life of the dispense assembly is reached and wherein the medical device is configured to indicate the end of life of the dispense assembly. The technical problem is further solved by a method according to the invention.
    Type: Grant
    Filed: January 31, 2013
    Date of Patent: May 21, 2019
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Caspers, Ilona Eggert
  • Patent number: 10293112
    Abstract: The invention relates to a disposable drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing, a cartridge holder for retaining a cartridge containing the medicament, a piston rod displaceable relative to the cartridge holder, a driver coupled to the piston rod, a display member for indicating a set dose and being coupled to the housing and to the driver, and a button coupled to the display member and to the driver.
    Type: Grant
    Filed: April 25, 2016
    Date of Patent: May 21, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: David Aubrey Plumptre
  • Patent number: 10293114
    Abstract: The invention relates to a drug delivery device comprising: a syringe with a body from which a needle extends and an inner sheath; a piston rod comprising a piston and an actuation head, a support sheath for holding the body. It is envisaged that the support sheath and the actuation head comprise corresponding indicators.
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: May 21, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Wendland, Anke Liewald, Frank Ricther, Caroline Stephan
  • Patent number: 10293111
    Abstract: The present invention concerns a drive mechanism (3) for a drug delivery device (1), which comprises a piston rod (40) comprising a first piston rod member (7) and a second piston rod member (8). The drive mechanism (3) further comprises an adjustment member (9). The drive mechanism (3) has a first state in which the first and the second piston rod member (7, 8) are moveable with respect to each other by operating the adjustment member (9), thereby adjusting the length of the piston rod (40), and wherein the adjustment member (9) is arranged at least partially inside the second piston rod member (8). Moreover, the present invention concerns a method for assembling the drug delivery device (1).
    Type: Grant
    Filed: August 15, 2014
    Date of Patent: May 21, 2019
    Assignee: Sanofi-Anentis Deutschland GMBH
    Inventors: Samuel Steel, Paul Richard Draper, Joseph Butler, David Richard Mercer
  • Patent number: 10293113
    Abstract: The present disclosure relates to a drive mechanism for an injection device for setting and dispensing of a dose of a medicament, the drive mechanism comprising: an inner body fixable inside a housing of the injection device, the inner body comprising an elongated shaft extending in an axial direction (z) and having an outer thread, a tubular-shaped display member having an inner thread engaged with the outer thread of the inner body, and a dose member axially displaceable between a dose setting position (S) and a dose dispensing position (D) relative to the display member, wherein the display member comprises at least one blocking member movable in axial direction (z) between a blocking position (B) and a release position (R) and engageable with a blocking structure on the outer circumference of the inner body, wherein when in blocking position (B) the blocking member axially engages with the dose member and with the blocking structure to block an axial displacement of the dose member from the dose settin
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: May 21, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: David Aubrey Plumptre, Robert Veasey, John David Cross
  • Patent number: 10298816
    Abstract: A method of assembling an apparatus for use in performing pattern recognition, the method involves placing a module and a housing relative to one another, the housing being supported relative to an object having an optical marker, and the module comprising a camera for generating a camera output indicative of a scene in the field-of-view of the camera, using the camera output to determine the position of the marker in the field-of-view of the camera, moving the module and the housing relative to one another until the marker is at a predetermined location in the field-of-view of the camera and then fixing the position of the module relative to the housing.
    Type: Grant
    Filed: April 16, 2014
    Date of Patent: May 21, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Martin Haupt, Roman Jiricka
  • Patent number: 10286155
    Abstract: A pen type drug injection device includes a housing, a dose dial member, a torsion spring fixed between the housing and the dial member such that energy is accumulated in the torsion spring upon rotation of the dial member relative to the housing, a drive member engaging a lead screw, a first clutch, and a second clutch. The first clutch couples the drive member and the housing, in a coupled state and allows relative rotation between them in a de-coupled state. The second clutch rotationally couples the drive member and the dial member in a coupled state and allows clockwise and anti-clockwise rotation between them in a de-coupled state. The second clutch includes a ratchet clicker with teeth having different tooth angles in the clockwise and the anti-clockwise direction, such that, in the de-coupled state, the teeth override each other with different resistance in opposite directions.
    Type: Grant
    Filed: September 3, 2014
    Date of Patent: May 14, 2019
    Assignee: Sanofi
    Inventors: Simon Lewis Bilton, David Aubrey Plumptre, Matthew Jones, Joseph Butler
  • Patent number: 10286154
    Abstract: An assembly for a drug delivery device (1) is proposed, comprising a housing (13) having a proximal end and a distal end, a dose member (23) which is displaceable in the proximal direction with respect to the housing for setting of a dose of a drug, a clutch member (28) which is displaced in the proximal direction with respect to the housing when setting the dose, and a stop member (30) configured to define a clutch stop position for the proximal displacement of the clutch member with respect to the housing, with the clutch member, when in the clutch stop position, being prevented from further displacement in the proximal direction with respect to the housing, wherein the clutch member and the dose member are configured to mechanically cooperate with one another when the clutch member is in the clutch stop position, thereby preventing further displacement of the dose member in the proximal direction with respect to the housing during setting of the dose. Furthermore, a drug delivery device (1) is proposed.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: May 14, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Strehl, Udo Leuschner, Norbert Besenhardt
  • Patent number: 10286145
    Abstract: The invention relates to a drive mechanism (9) for a needle insertion arrangement (1), the drive mechanism (9) comprising an actuator (5) coupled to a parallel linkage (10) adapted to convert a linear movement of the actuator (5) in a longitudinal direction (L) to a linear movement of a cross beam (7) in transverse direction (T) substantially at right angles with respect to the longitudinal direction (L).
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: May 14, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Schabbach, Meinolf Werner, Olaf Zeckai, Philippe Nzike
  • Patent number: 10286156
    Abstract: The present invention relates to a monitoring device for monitoring operation of a drug delivery device and to a respective drug delivery device, wherein the monitoring device comprises: a fastening member (32) to releasably attach the monitoring device to an axially elongated housing (14) of the drug delivery device (10), a sliding member (40) shiftable relative to the fastening member (32) in an axial direction (1, 2) and being adapted to operably engage with at least one dose setting component (17, 18, 26) of the drug delivery device (10) to follow an axial displacement of the dose setting component (17, 18, 26) relative to the housing component (14), a first sensor arrangement (36, 46) for detecting a rotation of the dose setting component (17, 18, 26) relative to the fastening member (32), a second sensor arrangement (38, 48) for detecting an axial displacement of the sliding member (40) relative to the fastening member (32), and a processing member (34) coupled to the first and to the second sensor a
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: May 14, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Jasmin Groeschke, Alexander Allerdings, Jan-Peter Spengler, Christoph Dette, Matthias Scharf, Andreas Bode, Michael Schrack
  • Patent number: 10286158
    Abstract: A medication delivery device and/or dosing mechanisms suitable for use in medication delivery devices, in particular in pen-type injectors, preferably having a dose setting system and a drive device enabling the administration of a medicinal product from a single- or multi-dose medication cartridge.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: May 14, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Michael Harms, Steffen Raab, Dominic George Webber, James Roberts Howarth, Trevor John Beckett, Geoffrey Philip Gray, John David Cross
  • Patent number: 10279118
    Abstract: A drive mechanism (11) for a delivery device comprising a drive member (17) for driving a piston rod (13); a moveable dose setting member (19, 35) being disengaged from the drive member (17) in a dose setting state and being moveable in a drive direction in a dose delivery state, wherein the dose setting member (19, 35) engages with the drive member (17) in the dose delivery state in such a manner that the movement of the dose setting member (19, 35) in the drive direction is transferred to the drive member (17); and a spring member (21) being coupled to the dose setting member (19, 35) in such a manner that the movement of the dose setting member (19, 35) in a setting direction loads the spring member (21) in the dose setting state, the spring force of the loaded spring member (21) driving the dose setting member (19, 35) in the drive direction in the dose delivery state.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: May 7, 2019
    Assignee: Sanofi
    Inventors: Tom Oakley, Matt Schumann, Mark Pawulski
  • Patent number: 10279116
    Abstract: A method and system for priming a drug delivery device. The drug delivery device includes a dose dial sleeve and an internal housing portion. The dose dial sleeve is coupled to the internal housing. The dose dial sleeve rotates on a substantially circumferential rotational path during priming of the drug delivery device. Further, the dose dial sleeve rotates on a helical path during dose setting of the drug delivery device.
    Type: Grant
    Filed: March 20, 2013
    Date of Patent: May 7, 2019
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: David Aubrey Plumptre, Christopher John Jones, Roberts Frederick Veasey
  • Patent number: 10279127
    Abstract: Described is a medicament delivery device having a case and a plurality of projections movable relative to the case between an extended position in which distal ends of the projections extends beyond a distal face of the case and a refracted position in which the distal ends of the projections are substantially co-planar with the distal face.
    Type: Grant
    Filed: September 3, 2013
    Date of Patent: May 7, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Charley Henderson, David Cross, Douglas Ivan Jennings, Ryan Anthony McGinley
  • Patent number: 10279130
    Abstract: Described is a medicament delivery device (100, 200) comprising a case (105, 205) adapted to hold a container with a medicament and a needle (300), a needle sleeve (120, 220) telescopically coupled to the case (105, 205) and having an extended position relative to the case (105, 205) in which the needle (300) is covered and a retracted position relative to the case (105, 205) in which the needle (300) is exposed, and a delivery initiation indicator providing a visual feedback of an initiation of a delivery of the medicament when the needle sleeve (120, 220) is in the retracted position.
    Type: Grant
    Filed: October 1, 2013
    Date of Patent: May 7, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Carsten Mosebach, Stefan Wendland
  • Patent number: 10272204
    Abstract: The present invention is directed to a drug delivery device comprising a cartridge with a movable bung, a drive mechanism including a bearing for driving the bung in a distal direction for delivering a medicament and a piston rod for actuating the bearing. An electric conductor for transmitting an electrical signal is provided, wherein the electric conductor is configured such that a conductive connection is established or interrupted when the piston rod contacts the bearing or when the bearing contacts the bung. The invention is further directed to a method for detecting the contact between the drive mechanism and the movable bung.
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: April 30, 2019
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Michael Jugl, Axel Teucher
  • Patent number: 10272202
    Abstract: Described is an injection device for administering a dose of a medicament (M) comprising a carrier adapted to contain a syringe having a hollow injection needle and a stopper, a drive spring, a plunger adapted to forward load of the drive spring to the stopper, and a noise component adapted to generate an audible and/or tactile feedback by impacting a component of the injection device when the stopper is located at a proximal end of the syringe. In a first state, a resilient arm on the plunger is maintained in engagement with the noise component by the carrier. In a second state, the arm disengages the noise component and deflects at least partially into an aperture in the carrier.
    Type: Grant
    Filed: January 31, 2018
    Date of Patent: April 30, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Simon Francis Brereton, Thomas Kemp
  • Publication number: 20190117684
    Abstract: The invention especially relates to multivalent vaccine compositions that can treat or prevent at least 60, preferably 75% of infections caused by Neisseria meningitidis especially of serogroup B. To this end, the invention in particular provides a lipooligosaccharide (LOS) of N. meningitidis in particular constituted by a lipid A, an inner core, an ? chain of L6 or L8 type, in which the heptose II residue of the inner core bears in position O-3 and in position O-6 or O-7 a phosphoethanolamine (PEA) substituent, and also to the construction of the strain of N. meningitidis that is capable of expressing such an LOS. The invention also relates to a strain of N. meningitidis of serogroup A that bears a lipooligosaccharide (LOS) in particular constituted by a lipid A, an inner core, an ? chain of L6 type, in which the heptose II residue of the inner core bears in position O-3 a phosphoethanolamine (PEA) substituent and does not bear a PEA substituent in positions O-6 and O-7.
    Type: Application
    Filed: November 1, 2018
    Publication date: April 25, 2019
    Applicant: Sanofi Pasteur SA
    Inventors: Noelle Mistretta, Monique Moreau, Genevieve Renauld-Mongenie, Bachra Rokbi
  • Patent number: 10265479
    Abstract: The invention relates to a reusable drug delivery device for selecting and dispensing a number of user variable doses of a medicament. The device comprises a housing, a cartridge holder for retaining a cartridge containing the medicament, a piston rod displaceable relative to the cartridge holder, a driver coupled to the piston rod, a display member for indicating a set dose and being coupled to the housing and to the driver, and a button coupled to the display member and to the driver.
    Type: Grant
    Filed: April 26, 2016
    Date of Patent: April 23, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: David Aubrey Plumptre, Thomas Frederick Osman
  • Patent number: 10265473
    Abstract: The present invention relates to a housing of a drug delivery device comprising a cylindrically shaped body (12) to accommodate a drive mechanism (13) and comprising a cartridge holder (14) to accommodate a cartridge (16) containing a dispensable medicament, the housing further comprising a connector assembly (20) to releasably interconnect body (12) and cartridge holder (14), the connector assembly (20) comprising: a tangentially extending recessed structure (30) with a tangential opening (31) to receive a radially extending pin (26), wherein the recessed structure (30) is fastened to one of body (12) and cartridge holder (14) and wherein the pin (26) is fastened to the other one of body (12) and cartridge holder (14), a release member (40) having a retaining portion (42) to cover the opening (31) in a locking configuration (60), wherein the release member (40) is displaceable in tangential direction (3) against a restoring force away from the recessed structure (30) into a release configuration (62), in whi
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: April 23, 2019
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventors: Stefan Blancke, Axel Teucher, Michael Jugl