Patents Assigned to Sanofi Pasteur Biologics Co.
  • Vaccines Against Japanese Encephalitis Virus and West Nile Virus
    Publication number: 20120201852
    Abstract: The invention provides attenuated Flavivirus vaccines, such as vaccines against Japanese encephalitis virus and West Nile virus, as well as methods of making and using these vaccines.
    Type: Application
    Filed: October 3, 2011
    Publication date: August 9, 2012
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Farshad Guirakhoo, J. Jian Liu, John A. Catalan, Thomas P. Monath, Konstantin V. Pugachev
  • Replication-Defective Flavivirus Vaccine Vectors Against Respiratory Syncytial Virus
    Publication number: 20120128713
    Abstract: Replication-defective vaccine vectors against respiratory syncytial virus (RSV) are disclosed. Corresponding compositions and methods employing the vaccine vectors are also disclosed.
    Type: Application
    Filed: March 16, 2010
    Publication date: May 24, 2012
    Applicants: Sanofi Pasteur Limited, Sanofi Pasteur Biologics Co.
    Inventors: Konstantin V. Pugachev, Alexander A. Rumyantsev, Maryann Giel-Moloney, Mark Parrington, Linong Zhang
  • Recombinant flavivirus vaccines
    Patent number: 8124398
    Abstract: The invention provides recombinant flavivirus vaccines that can be used in the prevention and treatment of flavivirus infection. The vaccines of the invention contain recombinant flaviviruses including attenuating mutations.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: February 28, 2012
    Assignee: Sanofi Pasteur Biologics Co.
    Inventors: Konstantin V. Pugachev, Farshad Guirakhoo, Thomas P. Monath
  • West nile virus vaccine
    Patent number: 8088391
    Abstract: The invention provides chimeric flavivirus vaccines against West Nile virus and methods of using these vaccines to prevent or treat West Nile virus infection.
    Type: Grant
    Filed: March 23, 2009
    Date of Patent: January 3, 2012
    Assignee: Sanofi Pasteur Biologics Co.
    Inventors: Juan Arroyo, Charles Miller, John Avram Catalan, Thomas P. Monath
  • Methods and Compositions for Increasing Toxin Production
    Publication number: 20110256606
    Abstract: The invention provides methods and compositions (such as for example, culture media) for culturing Clostridium difficile and producing the C. difficile Toxins A and B.
    Type: Application
    Filed: September 24, 2009
    Publication date: October 20, 2011
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Aiqi Fang, Andrew James White, Seshu Tummala, Lee Wilson
  • Vaccines against Japanese encephalitis virus and West Nile virus
    Patent number: 8029802
    Abstract: The invention provides attenuated Flavivirus vaccines, such as vaccines against Japanese encephalitis virus and West Nile virus, as well as methods of making and using these vaccines.
    Type: Grant
    Filed: October 19, 2005
    Date of Patent: October 4, 2011
    Assignee: Sanofi Pasteur Biologics Co.
    Inventors: Farshad Guirakhoo, J. Jian Liu, John A. Catalan, Thomas P. Monath, Konstantin V. Pugachev
  • Compositions and Methods for the Production of Alpha-Herpesviruses
    Publication number: 20110201087
    Abstract: The present invention relates to virus growth media that improve the yield of alpha-herpesviruses (e.g., HSV-2) grown in cell cultures. The growth media of the invention include two additives, a disaccharide and a lipid mixture, that can be added to serum-free or serum-enriched growth media to improve the efficiency of virus production. The invention further provides methods of producing alpha-herpesviruses (e.g., HSV-2) in such growth media.
    Type: Application
    Filed: August 11, 2009
    Publication date: August 18, 2011
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Simon Delagrave, Rachid Oubelaid, John Hamberger
  • Replication-Defective Flavivirus Vaccines and Vaccine Vectors
    Publication number: 20110135686
    Abstract: This invention provides replication-defective flavivirus vaccines and vaccine vectors, and corresponding compositions and methods.
    Type: Application
    Filed: March 16, 2009
    Publication date: June 9, 2011
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Konstantin V. Pugachev, Alexander A. Rumyantsev, Maryann Giel-Moloney, Harold Kleanthous
  • Influenza B Vaccines
    Publication number: 20110110973
    Abstract: This invention relates to immunogenic compositions including influenza B virus sequences, and methods of using such compositions.
    Type: Application
    Filed: February 9, 2009
    Publication date: May 12, 2011
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Kirill Kalnin, Ashley Birkett, Patricia Londono-Arcila, Svetlana Stegalkina, Yanhua Yan
  • Recombinant Rhinovirus Vectors
    Publication number: 20110091501
    Abstract: The invention provides rhinovirus vectors, which can be used in the delivery of immunogens, such as influenza virus immunogens, and corresponding compositions and methods.
    Type: Application
    Filed: March 27, 2009
    Publication date: April 21, 2011
    Applicant: SANOFI PASTEUR BIOLOGICS CO.
    Inventors: Kirill Kalnin, Yanhua Yan, Maryann Giel-Moloney, Harold Kleanthous
  • Pharmaceutical Compositions Containing Clostridium Difficile Toxoids A and B
    Publication number: 20110045025
    Abstract: This invention relates to compositions including Clostridium difficile toxins and/or toxoids and corresponding methods. The compositions of the invention include one or more excipients that increase stability and/or decrease aggregation of the toxins.
    Type: Application
    Filed: September 15, 2008
    Publication date: February 24, 2011
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Russell C. Middaugh, Richard Fahrner, Peter Ciarametaro
  • Chimeric flavivirus vectors
    Publication number: 20110014229
    Abstract: The invention provides chimeric flavivirus vectors including foreign peptides inserted into the envelope proteins of the vectors and methods of using these vectors.
    Type: Application
    Filed: July 14, 2009
    Publication date: January 20, 2011
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Harold Kleanthous, Charles Miller, Larisa Oros
  • Novel Neutralizing Immunogen (NIMIV) of Rhinovirus and its Use for Vaccine Applications
    Publication number: 20100297169
    Abstract: The invention relates to methods and compositions for preventing or treating human rhinovirus infection.
    Type: Application
    Filed: October 1, 2007
    Publication date: November 25, 2010
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Kirill Kalnin, Yanhua Yan, Harold Kleanthous
  • Flavivirus Vaccine Vector Against Influenza Virus
    Publication number: 20100255028
    Abstract: This invention relates to chimeric flavivirus vectors that can be used, for example, in the prevention and treatment of influenza virus infection, compositions including such viral vectors, and methods employing the vectors.
    Type: Application
    Filed: January 31, 2008
    Publication date: October 7, 2010
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Simon Delagrave, Farshad Guirakhoo, Caroline Maier, Alexander A. Rumyantsev
  • Stabilization of Vaccines by Lyophilization
    Publication number: 20100247573
    Abstract: This invention provides pharmaceutical compositions, such as vaccines, and methods of making and using such compositions.
    Type: Application
    Filed: November 7, 2007
    Publication date: September 30, 2010
    Applicant: SANOFI PASTEUR BIOLOGICS CO.
    Inventors: Daniel C. Vellom, James E. Woiszwillo, Amy Woiszwillo, Dara O'Neil, Jennifer Woiszwillo, Cole Woiszwillo, Paul DeGeorge, Peter Ciarametaro
  • Recombinant Rhinovirus Vectors
    Publication number: 20100239605
    Abstract: The invention provides recombinant rhinovirus vectors including, for example, influenza virus antigens. Also provided by the invention are corresponding pharmaceutical compositions and methods.
    Type: Application
    Filed: October 1, 2007
    Publication date: September 23, 2010
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Kirill Kalnin, Yanhua Yan, Harold Kleanthous
  • Construction of Recombinant Virus Vaccines by Direct Transposon-Mediated Insertion of Foreign Immunologic Determinants into Vector Virus Proteins
    Publication number: 20100184832
    Abstract: The invention provides viral vectors, such as chimeric flavivirus vectors, including foreign peptides inserted into the target proteins of the vectors, methods of making and using these vectors, and compositions including the vectors.
    Type: Application
    Filed: July 16, 2007
    Publication date: July 22, 2010
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Konstantin V. Pugachev, Alexander A. Rumyantsev
  • West Nile Virus Vaccine
    Publication number: 20100086564
    Abstract: The invention provides chimeric flavivirus vaccines against West Nile virus and methods of using these vaccines to prevent or treat West Nile virus infection.
    Type: Application
    Filed: March 23, 2009
    Publication date: April 8, 2010
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Juan Arroyo, Charles Miller, John Avram Catalan, Thomas P. Monath
  • Recombinant Bicistronic Flavivirus Vectors
    Publication number: 20100034849
    Abstract: This invention relates to bicistronic flavivirus vectors, methods of using such vectors in the prevention and treatment of disease, and methods of making such vectors.
    Type: Application
    Filed: January 31, 2008
    Publication date: February 11, 2010
    Applicant: Sanofi Pasteur Biologics Co.
    Inventors: Simon Delagrave, Nathan Brown, Harold Kleanthous, Farshad Guirakhoo, Alexander Rumyantsev
  • Vaccinia virus strains
    Patent number: 7645456
    Abstract: The invention provides attenuated vaccinia virus vaccines that can be used in methods to prevent or treat small pox in patients, as well as methods of obtaining such vaccines.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: January 12, 2010
    Assignee: Sanofi Pasteur Biologics Co.
    Inventors: Richard A. Weltzin, Thomas P. Monath