Abstract: The present invention relates to a sheet material and filter element, where the sheet material and the filter element have a hydrophobic separating layer, and also to use thereof and to a process for production of same.

Abstract: A mixing vessel for accommodating components to be mixed has a container with at least one mounting depression in a side wall of the container. The mounting depression is adapted so that a mixing impeller housing of a mixing impeller is at least partly insertable, in which at least one magnet is housed for being magnetically connectable to a drive device to be driven. A locking assembly is attachable to the mounting depression from outside for locking the mixing impeller in a storage position, in which the mixing impeller is not rotatable. The locking assembly has a magnetically active element that is adapted to interact with the magnet of the mixing impeller.

Abstract: The invention relates to a service unit that can be carried on the body of a user by means of a carrying system, having at least one power source for supplying power to electrically operated tools connectable to the power source, the power source being formed from at least one rechargeable battery. The invention also relates to a method for monitoring and documenting maintenance work. The invention is distinguished in that the carrying system has an integrated computation and documentation unit for monitoring and documenting maintenance work, wherein the computation and documentation unit is powered from the power source, wherein the computation and documentation unit is connected to at least one motion sensor and/or locating sensor and wherein the motion sensor is arranged on the tool or the hand of the user.

Abstract: Aeration device for bioreactors with an aeration element with gas outlet openings arranged in a housing, the aeration element taking the form of a microsparger, the gas outlet openings of which are in each case spaced apart from one another and have a size of between 100 ?m and 200 ?m. At least one second aeration element with gas outlet openings of a second size is preferably provided, the aeration elements being formed by a common housing with separate aeration channels.

Abstract: A mixing device for mixing contents of a container has a support for supporting the container and a moving device connected to the support for moving the support and mixing the contents of the container. The support has a positioning device to position the container so that a removal side of the container is arranged substantially along a predetermined line of the support. The support is pivotable about a removal pivot axis to move the container into a removal position. The removal pivot axis is at an angle of over 0° to 45° to the predetermined line of the support so that the container can be moved from the mixing position by pivoting the support about the removal pivot axis into the removal position where the removal side is on a lower side of the container and inclined toward a removal region of the container.

Abstract: A single use probe, sterilizable by irradiation, for a single use component which is provided for use in a biopharmaceutical process, comprises at least one sensor relevant for the biopharmaceutical process, an RFID tag and a memory rewritable in principle, in which data with respect to an integrity check of the single use probe are stored.

Abstract: The present invention relates to a method for determining the functionality and integrity of depth filter sheets and depth filter sheet systems comprising inorganic layered double hydroxide for contaminant removal in biotechnological processes.

Abstract: The present invention relates to a micro-porous filtration membrane with performance enhancing multi-level macro-scopic cavities as well as a method for producing the same.

Abstract: A mixing and thawing device (1) has a rocker drive (2) and a bag holder (3) for holding a bag (7). The bag holder (3) has a base part (8) and a lid part (9) that enclose a holding space (10) for the bag (7). A heating element (11) is arranged in the base part (8). Thus, the holding space (10) is designed as a heat-insulating closed chamber. Interconnected intermediate spaces (14, 15) are arranged between the bag (7) and the base part (8) and between the bag (7) and the lid part (9). One or more flow generators (16) are provided to generate a circulating fluid flow (17).

Abstract: A computer system and computer-implemented method are described for controlling and monitoring a process to produce a chemical, pharmaceutical or biotechnological product. The method includes providing a database that stores sets of process parameters to control and monitor a plurality of processes performed in order to produce products, receiving a set of characterizing process parameters that characterize the process, identifying a first set process parameters from the stored sets of process parameters, and controlling and monitoring the process using a successful trajectory that includes a time-based profile of measurements.

Abstract: The present invention relates to a lateral flow membrane arrangement (1), comprising a microporous membrane layer (2) and a liquid-impermeable support layer (3), for lateral flow of a liquid through the microporous membrane layer (2), wherein the microporous membrane layer (2) is supported on the liquid-impermeable support layer (3) and has at least one detection zone (5) and at least one non-detection zone, wherein binding agents are immobilized in the at least one detection zone (5), the liquid-impermeable support layer (3) has at least one zone having a large thickness and at least one zone having a small thickness, the microporous membrane layer (2) is supported on the liquid-impermeable support layer (3) such that said at least one detection zone is provided above said at least one zone of the support layer having a large thickness and said at least one non-detection zone is provided above said at least one zone of the support layer having a small thickness, the zones are oriented in a direction orthogon

Abstract: Container system with one container (1) with a flexible partition, in particular a disposable container, that can be inserted into a carrying container that supports its lateral container partition (10) and in which liquid medium (8) that has been poured in can be mixed, with the carrying container (4) featuring at least one baffle (15, 15?, 15?, 15??) on the internal support partition (11) that forms the lateral container partition.

Abstract: The present invention relates to a method for separating viruses from a contaminant-containing liquid medium using two adsorbents having cationic groups, wherein the viruses are adsorbed to the first adsorbent and subsequently eluted and wherein the contaminants present in the resulting eluate are subsequently adsorbed to the second adsorbent. The yield and purity of the viruses obtained as per the method according to the invention is increased by the addition of multivalent anions during the adsorption of the contaminants to the second adsorbent.

Abstract: A method for implementing a channel (56) includes providing a preform (20) having a recess (22) therein and heating a channel implementation element (30?) to a temperature greater than a melting temperature of a material of the preform (20). An external contour of the channel implementation element (30?) at least regionally corresponds to an internal contour of the channel (56) to be implemented. The method then moves the heated channel implementation and/or the preform (20) in relation to one another so that the heated channel implementation element (56) at least regionally moves into the recess (22) in a moving-in direction. The material of the preform (20) is at least partially melted in a region around the recess (20) and is at least partially displaced by the channel implementation element (30?), wherein at least a part of the channel (56) to be implemented is thus implemented.

Abstract: Bioreactor with a vessel having at least one gas dissipation duct for gas discharge, the orifice of the gas dissipation duct being connected to a hydrophobic sterile filter and to a condenser arranged between them and having condensation surfaces, a turbulence generator for generating a turbulent flow is arranged in the gas dissipation duct in the region of the condenser.

Abstract: The invention relates to an installation for biotechnological applications (1, 101), comprising an improved holder system (4) with at least one carrier (10) for the mounting of components (5) of the installation (1, 101) on the installation (1, 101). The carrier (10), which comprises a frame (12) with two arms (14) and with a recess (16) and includes a deformable element (30) with at least two fastening sections (32), which may be understood to have a flat base (20) by which the carrier (10) can be fastened to the installation (1, 101). The deformable element (30) is designed to assume the following states: a receiving state AUZ, in which the deformable element (30) is available for receiving a component (5) of the installation (1, 101); and a locking state ARZ.

Abstract: The invention relates to an annular connection clamp with a first clamping flange (22) which protrudes radially inwards and with an axial counter bearing (24) which is spaced from the clamping flange and which is made of a first and a second half-ring segment (20), each half-ring segment having a first and a second segment end. The first segment end of the first half-ring segment (20) has latching means (281) of a first type, and the second segment end of the second half-ring segment has corresponding latching means (282) of a second type, said latching means being pushed into each other in a tangential direction, thereby being latchable together. The second segment end of the half-ring segment (20) has latching means (282) of a second type, and the first segment end of the second half-ring segment (20) has latching means (281) of a first type, said latching means being pushed into each other in a tangential direction, thereby being latchable together.

Abstract: A mixing device (10) comprises a flexible container (14), at least one stirring element (22) and at least one baffle (24). The baffle (24) is formed on the inside on a circumferential side wall (16) of the flexible container (14) and has a free end protruding into the interior of the container (14). A main application of the mixing device (10) is considered to be the use as disposable bioreactor.

Abstract: A container (1) has a measuring-cell housing (5) that protrudes into the container interior (2). The measuring-cell housing (5) has a measuring gap (6) bounded by two opposed spaced-apart lateral surfaces (8, 9), and a connecting surface (10) connects the lateral surfaces (8, 9). Each lateral surface (8, 9) has an optical window (11, 12). A first optical fiber (15, 15?) is arranged before the first window (11) and a second optical fiber (17, 17?) is arranged before the second window (12). Receiving channels (14, 16, 18) are arranged before the windows (11, 12, 13) and subsequently can be fit with the optical fibers (15, 15?, 17, 17?, 19) from the outside. The measuring-cell housing (5) having the windows (11, 12, 13) and the receiving channels (14, 16, 18) is connected fixedly to the wall (3) of the container interior (2).

Abstract: The present invention relates to a method for determining the logarithmic reduction value LRV of a size-exclusion filter for a particle of a process solution, which particle is to be clarified, the size-exclusion filter being protected from a blocking adsorbing species present in the process solution by a process adsorber which is connected upstream in series.