Abstract: A method for detecting and classifying defects in high-throughput transparent articles such as syringes, vials, cartridges, ampules, and bottles is provided. The method includes the steps of providing a stream of the articles; capturing a first digital image of each of the articles in the stream; inspecting the first digital image for objects; determining parameters of the objects; performing a first classification step to classify the objects into a first defect class and a second defect class; performing a second classification step to classify the objects into a plurality of defect types using at least two second classification models; comparing at least one object parameter of a classified object with a predetermined defect type dependent threshold; classifying the article as defective or non-defective based on the comparing step; and separating defective articles from non-defective articles.

Abstract: A pre-Tillable or prefilled container for at least one of storage or application of a fluid includes: a receptacle having a chamber for accommodation of the fluid; a cannula assembly including a cannula and a sealing element, the cannula having an outside channel opening, the cannula assembly being attachable to the receptacle; and a closure cap including a sealing. The channel opening of the cannula protrudes into the sealing of the closure cap thus sealing the channel opening. Due to at least one of a radial compression or an axial compression of the sealing element, as well as due to sealing of the channel opening by the closure cap, the chamber is sealed in a fluid-tight manner.

Abstract: A device for the shaping of glass bodies, in particular of pharmaceutical vials, comprises a clamping chuck for holding a glass body, a rotary drive for driving the clamping chuck rotatingly, further at least one heat source for heating a glass body held within the clamping chuck, and further a controller which is coupled to the rotary drive so that the clamping chuck can be driven at variable rotational speed.

Abstract: The present disclosure provides a tube catcher for a hot forming machine comprising a foot for mounting the tube catcher in the hot forming machine, an upper contact surface for catching a glass tube as it falls into the hot forming machine, and a damping element, which is arranged below the upper contact surface in such a way that it allows the upper contact surface to elastically recede in the direction of the falling direction of the glass tube. This minimizes damage to glass tubes on impact and permits a high production speed. For this purpose, the damping element includes a compressible chamber that can be filled with a gas.

Abstract: A method for molding end portions on glass containers that store pharmaceutical active ingredients is provided. The glass containers are produced from a glass tube by hot-forming, an end portion having a neck opening using a centrally disposed opening forming tool interacting with a shaping tool at one end of the glass containers. In the method, dimensional data is provided for the respective glass tube and the position of the shaping tool is adjusted in a motorized manner in the axial direction (z) of the glass containers so as to correspond to the provided dimensional data for the respective glass tube.

Abstract: A method and device for the continuous heat treatment of pharmaceutical glass containers are provided. The method includes continuously conveying glass containers from an entry region to an exit region via a conveying installation having a separating plate made from an electrically conductive material, the separating plate being positioned above and/or below the conveying installation; heating the glass containers to a maximum temperature in a heating zone after passing the entry region; cooling the glass containers in a first cooling zone after passing the heating zone and before passing the exit region at a first cooling rate, wherein the separating plate separates the glass containers from heating installations in the heating zone and/or temperature changing installations in the first cooling zone; and controlling the heating installations and/or the temperature changing installations to inductively heat the separating plate in the heating zone and/or the first cooling zone.

Abstract: A positioning device for a preloading ring of a hot forming machine is provided. The device has a first holding element and a second holding element. The first holding element has a first recess and a second recess. The second recess is at a distance radially with respect the first recess. The second holding element is arranged in a region of and faces the first and second recess. The first and second holding elements are configured and arranged movably about respective axes with respect to each other so that movement towards each other encloses a glass tube in each of the first and second recesses and between the holding elements.

Abstract: A hot-forming device is provided for producing glass containers from a glass tube. The device includes a rotary table mounted so as to be rotationally movable and an assigned drive motor for driving the rotary table. The rotary table includes several holding chucks for holding workpieces distributed around the circumference of the rotary table. The rotary table has a coolant channel that is fluid-tight and through which a coolant can flow to cool.

Abstract: A pharmaceutical container for drug delivery includes a barrel configured to slidably receive a stopper. The container exhibits a ratio of a break loose force (BLF) relative to a glide force (GF) of BLF/GF?2 during a break loose and glide force test and a total glide force variation TGFV=GFmax?GFmin measured when the stopper is moved from a start position to its end position is TGFV<2 N.

Abstract: A combination includes: a holding structure including receptacles which are arranged in a regular arrangement and are formed by peripherally formed side walls; containers received in the receptacles, the containers having a basic body which, at an upper end, merges into a shoulder portion which is adjoined by a narrowed neck portion with a widened upper edge with an opening; holding projections provided at lower ends of the receptacles and configured to hold the containers in the receptacles, the holding projections at the lower ends protruding radially inwards into the receptacles, the containers being supported directly on the holding projections; and centering elements provided above the holding projections and configured to center the containers in the receptacles. The centering elements have a beveled configuration and protruding into the receptacles in order to reduce a width of the receptacles at the lower ends thereof in a funnel shape.

Abstract: The present invention relates to a holding structure for simultaneously holding a plurality of containers for substances for pharmaceutical, medical or cosmetic applications or of devices having such containers, having a plurality of receptacles. The receptacles are arranged in a regular arrangement and are formed by in each case peripherally formed side walls. The receptacles have in each case one or two widened clearances having a dimension which is greater than the width of a gap between the containers received in the receptacles and side walls of the receptacles in the regions other than the widened clearances. The widened clearances additionally make available space for access to containers or devices which are received in the receptacles for handling thereof.

Abstract: A hot-forming tool for producing glass containers is provided. The tool includes a forming roller, a holder, and a heat sink. The forming roller has a forming surface. The holder receives the forming roller with the forming roller rotatably mounted on the holder. The heat sink is directly or indirectly connected to the holder. The forming roller is in thermal contact with the heat sink and the heat sink has an internal cooler so that process heat can be transferred from the forming roller to the heat sink.

Abstract: A transport unit for a packaging structure for a plurality of containers for substances for pharmaceutical, medical or cosmetic uses includes a tray with a plurality of seats for positioning the containers and a planar inlay part for covering the containers positioned in the seats of the tray. The inlay part is configured to cover the containers positioned in the seats and at the same time to be received completely in the tray, without protruding above an upper edge of the tray. A plurality of depressions corresponding to the seats of the tray are formed in the inlay part, in order to position the containers at their two ends lying opposite each other. A gap is formed at least partially between the inlay part, received in the tray, and side walls of the tray.

Abstract: An apparatus for producing a glass workpiece includes: a device configured to heat a glass until it softens; an inner molding tool configured to mold inner lateral surfaces of the workpiece; an outer molding tool configured to mold outer lateral surfaces of the workpiece, the outer molding tool having a shaping roller with a shaping surface; an accommodating device configured to accommodate the shaping roller, the shaping roller being mounted in a freely rotatable manner in the accommodating device and is fixable during a shaping process by a lockable locking device, the shaping roller being locked with a releasable connection such that the shaping roller can be released and rotated through an angle ? in the locking device between individual shaping processes; and an apparatus configured to apply a lubricating oil to the shaping surface of the shaping roller and having an outlet opening configured to dispense the lubricating oil.

Abstract: A syringe body for a pharmaceutical syringe is provided. The syringe includes cylindrical cavity, a finger flange, and an anti-slip element. The cylindrical cavity has a first end face with a cone and a second, open end face configured to receive a piston. The finger flange is arranged around a circumference of the second, open end face. The finger flange has a first surface that faces the cone. The anti-slip element is a roughened area on the first surface. The roughened area exhibits an arithmetic mean roughness value between 0.8 ?m and 150 ?m.

Abstract: A primary packaging container for pharmaceuticals is provided. The container includes a hollow body, an opening, and a closure. The hollow body has an opening and is made of a cycloolefin polymer or a cycloolefin copolymer. The closure has a puncture region. The closure closes the opening with the puncturing region at the opening. The puncturing region is configured to allow introduction of a cannula into the hollow body and resealing the hollow body upon withdraw of the cannula. The closure has an elastomer that is connected to the hollow body so as to be not separable in a non-destructive manner.

Abstract: A syringe includes a syringe body, which has a cylindrical portion and, adjoining the latter, a frustoconical portion, and a Luer lock connector, which has a Luer collar with an inner thread and a Luer cone with a through-channel. A bottom surface is formed between the Luer collar and Luer cone. The syringe body and the Luer lock connector are formed in one piece and are made of a cyclic olefin resin. The Luer collar has reinforcing ribs on its outer face.

Abstract: A method for controlling a rotary drive of a hot forming machine having a plurality of processing stations arranged in a circular manner and a rotary table arranged thereabove, in which glass tubes to be processed are held and moved from one processing station to the next by a stepwise rotary movement, is provided. The rotary table is driven by a step gear by which a movement of a drive shaft is translated into a cyclic step movement, a step cycle of which comprises a movement phase and a subsequent standstill phase. A first value for the angular velocity of the drive shaft is assumed at a first time in the movement phase of the step cycle and a second value different from the first value is assumed at a second time in the standstill phase of the same step cycle.

Abstract: A closure piece is provided for the releasable closure of an opening at the distal end of a cylindrical container for pharmaceutical preparations. The container may be a syringe with a Luer lock fastening. The closure piece includes a cylindrical closure cap, with a cylindrical cavity for receiving and retaining a sealing element, and a sealing element. The sealing element has a rearward offset in relation to an outer edge of the closure cap.

Abstract: A supporting structure for concurrently supporting a plurality of containers for substances for pharmaceutical, medical or cosmetic applications, comprises a plurality of receptacles. The receptacles are arranged in a regular arrangement, are formed by circumferential side-walls, and an upper side of the supporting structure is formed as a plate-shaped carrier. The receptacles are polygonal in shape when viewed in a plan view. A side-wall is formed as a common partition wall between respective two directly adjacent receptacles of the plurality of receptacles. The receptacles can be directly adjacent to each other, which enables optimum packing density, especially with a hexagonal basic shape of the receptacles. Due to the shared partition wall, filigree, double-walled structures can be effectively avoided, which considerably simplifies production by injection molding from a plastic material. Thereby, also a very high inherent stiffness of the supporting structure can be achieved.