Patents Assigned to Sciences
  • EXPRESS INTERFACE APPARATUS USING OPTICAL CONNECTION
    Publication number: 20110116807
    Abstract: An express interface apparatus using an optical connection is provided. The apparatus connects between a central processing unit (CPU) in a computer system and an external device supporting optical signal transfer using a peripheral component interconnect express (PCIE) supporting high-speed signal processing.
    Type: Application
    Filed: January 29, 2010
    Publication date: May 19, 2011
    Applicant: KAIST (Korea Advanced Institute of Science and Technology)
    Inventors: Hyo Hoon PARK, Tae Woo LEE, Min Hyuk LEE, Mu Hee CHO, Seong Woon KIM
  • Manipulation of Microparticles In Microfluidic Systems
    Publication number: 20110118139
    Abstract: An array of transportable particle sets is used in a microfluidic device for performing chemical reactions in the microfluidic device. The microfluidic device comprises a main channel and intersecting side channels, the main channel and side channels forming a plurality of intersections. The array of particle sets is disposed in the main channel, and the side channels are coupled to reagents. As the particle sets are transported through the intersections of the main channel and the side channels, reagents are flowed through the side channels into contact with each array member (or selected array members), thereby providing a plurality of chemical reactions in the microfluidic system.
    Type: Application
    Filed: January 27, 2011
    Publication date: May 19, 2011
    Applicant: CALIPER LIFE SCIENCES, INC.
    Inventors: Tammy Burd Mehta, Anne R. Kopf-Sill, J. Wallace Parce, Andrea W. Chow, Luc J. Bousse, Michael R. Knapp, Theo T. Nikiforov, Steve Gallagher
  • Silicon Whisker and Carbon Nanofiber Composite Anode
    Publication number: 20110117436
    Abstract: A carbon nanofiber can have a surface and include at least one crystalline whisker extending from the surface of the carbon nanofiber. A battery anode composition can be formed from a plurality of carbon nanofibers each including a plurality of crystalline whiskers.
    Type: Application
    Filed: November 17, 2010
    Publication date: May 19, 2011
    Applicant: Physical Sciences, Inc.
    Inventors: Junqing Ma, Aron Newman, John Lennhoff
  • MULTI-ELECTRODE MEASURING SYSTEM
    Publication number: 20110115473
    Abstract: The invention provides a multi-electrode measuring system including a front end device which is a sensing device including a multi-electrode sensing device having a plurality of electrodes; a multi-channel fixture coupled to the multi-electrode sensing device; and a reference electrode. A back-end device as a virtual instrumentation is an electronic device including a read out circuit device coupled to the multi-channel fixture and the reference electrode for receiving each original signal from each electrode of the multi-electrode sensing device and the reference electrode determining a sample solution; a data acquisition device coupled to the read out circuit device for digitizing each original signal to form a digital signal and for array sampling; and a signal processing device coupled to the data acquisition device for processing each signal.
    Type: Application
    Filed: May 11, 2010
    Publication date: May 19, 2011
    Applicant: NATIONAL YUNLIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Jung-Chuan Chou, Wei-Chuan Chen, Cheng-Wei Chen, Chien-Cheng Chen
  • SYSTEM FOR REDUCING DISTORTION IN AN ELECTRONIC CIRCUIT USING NONLINEAR FEEDBACK
    Publication number: 20110115559
    Abstract: System and methods for reducing third harmonic distortion produced by nonlinear amplifiers are disclosed. A system may include an amplifier circuit with an amplifier transistor such that the amplifier is capable of exhibiting an amplifier output signal containing third harmonic distortion. Further, a system may include a nonlinear feedback circuit with a first feedback transistor operating in Triode mode that produces a feedback electronic signal containing a feedback third harmonic component. In addition, the nonlinear feedback circuit may be configured to the amplifier circuit in negative feedback such that the feedback third harmonic component of the feedback electronic signal reduces the third harmonic distortion of the amplifier output signal. A system may also provide an output signal that has less third harmonic distortion than the amplifier output signal.
    Type: Application
    Filed: December 30, 2009
    Publication date: May 19, 2011
    Applicant: INDIAN INSTITUTE OF SCIENCE
    Inventors: Bharadwaj Amrutur, Madhusudan Srinivasan, Bhavani Pradeep K.
  • RAPID CONFOCAL MICROSCOPY TO SUPPORT SURGICAL PROCEDURES
    Publication number: 20110116694
    Abstract: One embodiment of techniques for confocal microscopy includes illuminating a spot on a surface of a biological sample. A first emission intensity from the spot is detected in a first range of optical properties; and a second emission intensity in a second range. A pixel that corresponds to the spot is colored using a linear combination of the first and second emission intensities. Sometimes, the pixel is colored to approximate a color produced by histology. In some embodiments, a surface of a sample is contacted with a solution of acridine orange. Then, a spot is illuminated with a laser beam of wavelength about 488 nanometers (nm). Fluorescence emission intensity is detected above about 500 nm. Sometimes, a certain illumination correction is applied. In some embodiments, a sample holder that compresses a sample is removable from a stage that is fixed with respect to a focal plane of the microscope.
    Type: Application
    Filed: July 24, 2009
    Publication date: May 19, 2011
    Applicants: SLOAN KETTERING INSTITUTE FOR CANCER RESEARCH, OREGON HEALTH & SCIENCE UNIVERSITY
    Inventor: Daniel S. Gareau
  • CARBAMOYL DERIVATIVES OF BICYCLIC CARBONYLAMINO-PYRAZOLES AS PRODRUGS
    Publication number: 20110118278
    Abstract: There are provided bicyclic carbonylamino-pyrazoles of formula (I), wherein the variables are as specified in the claims, for use as medicament, in particular for the treatment of diseases due to the malfunctioning of protein kinases (PKs), such as cancer, pharmaceutical compositions comprising such carbamoyl derivatives, and their use as prodrugs of therapeutically active agents. Method of treatment and some new bicyclic carbonylamino-pyrazoles are also object of the present invention.
    Type: Application
    Filed: May 14, 2009
    Publication date: May 19, 2011
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Maurizio Pulici, Paolo Polucci
  • LIGHT EMITTING DIODE STRUCTURE, A LAMP DEVICE AND A METHOD OF FORMING A LIGHT EMITTING DIODE STRUCTURE
    Publication number: 20110114970
    Abstract: A light emitting diode structure, a lamp device and a method of forming a light emitting diode structure are provided. The structure has a substrate coated with a first reflective material; an electrode coated with a second reflective material, one or more layers of light emitting material, the layers disposed between the substrate and electrode; wherein in use, the first reflective material and second reflective material reflects light out of the structure via at least one light emitting surface and in a direction away from the electrode.
    Type: Application
    Filed: April 23, 2008
    Publication date: May 19, 2011
    Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
    Inventors: Jinghua Teng, Soo Seng Norman Ang, Soo Jin Chua
  • METHOD AND APPARATUS FOR PERFORMING PARALLEL BOX FILTERING IN REGION BASED IMAGE PROCESSING
    Publication number: 20110116727
    Abstract: A method and apparatus for performing parallel box filtering in region based image processing is provided. The method of performing parallel box filtering in region based image processing includes selecting parallel pixel blocks having a size of M×N to be operated in parallel, selecting pixels included in a mask region having a size of K×L that is a parallel pixel operation region and a first region having a size of (M+K?1)×(N+L?1) that corresponds to overlapping masks of M*N, selecting pixels of a second region commonly included in the mask regions of M*N and storing the results of operation with respect to the pixels of the second region as repeated operation values, and operating block operation values with respect to the parallel pixel blocks using the repeated operation values.
    Type: Application
    Filed: October 29, 2010
    Publication date: May 19, 2011
    Applicant: Daegu Gyeongbuk Institute of Science and Technolog y
    Inventors: Soon Kwon, Jong Hun Lee, Kyeong Ryeol Bae, Byung In Moon
  • CHROMATOGRAPHY LIGAND
    Publication number: 20110118442
    Abstract: The present invention relates to a chromatography ligand defined by the following formula R1—R2—N(R3)—R4—R5 wherein R1 is a substituted or non-substituted phenyl group; R2 is a hydrocarbon chain comprising 0-4 carbon atoms; R3 is a hydrocarbon chain comprising 1-3 carbon atoms; R4 is a hydrocarbon chain comprising 1-5 carbon atoms; and R5 is OH or H. The invention also comprises a separation matrix, comprising the described ligands coupled to a porous support, such as particles or a membrane. The ligand and matrix according to the invention is useful for purification of biomolecules or organic compounds, such as proteins, polypeptides, DNA etc. An advantageous use according to the invention is the purification of antibodies.
    Type: Application
    Filed: January 4, 2011
    Publication date: May 19, 2011
    Applicant: GE HEALTHCARE BIO-SCIENCES AB
    Inventors: CARINA ENGSTRAND, Annika Forss, Gunnar Glad, Bo-Lennart Johansson, Hans J. Johansson, Jean-Luc Maloisel
  • ANTIBODIES THAT IMMUNOSPECIFICALLY BIND TO B LYMPHOCYTE STIMULATOR PROTEIN
    Publication number: 20110117093
    Abstract: The present invention relates to antibodies and related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention also relates to methods and compositions for detecting or diagnosing a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate function of B Lymphocyte Stimulator comprising antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator. The present invention further relates to methods and compositions for preventing, treating or ameliorating a disease or disorder associated with aberrant B Lymphocyte Stimulator expression or inappropriate B Lymphocyte Stimulator function comprising administering to an animal an effective amount of one or more antibodies or fragments or variants thereof or related molecules that immunospecifically bind to B Lymphocyte Stimulator.
    Type: Application
    Filed: October 28, 2010
    Publication date: May 19, 2011
    Applicant: HUMAN GENOME SCIENCES, INC.
    Inventors: Steven M. RUBEN, Steven C. BARASH, Gil H. CHOI, Tristan VAUGHAN, David HILBERT
  • MARKER GENES FOR SCREENING OF DRUG-INDUCED TOXICITY IN HUMAN CELLS AND SCREENING METHOD USING THE SAME
    Publication number: 20110118127
    Abstract: The present invention relates to a marker gene for screening a drug inducing toxicity in human and a screening method using the same. More precisely, the invention relates to a microarray on which marker genes up-or down-regulated specifically by 16 drugs inducing pulmonary toxicity, teratogenicity, nephrotoxicity, cardiotoxicity or mutation (Methotrexate, Nitrofurantoin, Amiodarone, Carbamazepine, Valproic acid, Thalidomide, Cisplatin, Gentamycin, Amphotericine, Furylfuramide, N-nitroso-N-methylurea, methylmethanesulfonate, 4-nitroquinoline-N-oxide, 2-nitrofluorene, Doxorubicin and Daunorubicin) are integrated, a kit comprising the said microarray, and a screening method of a drug inducing toxicity in human using the same.
    Type: Application
    Filed: March 9, 2010
    Publication date: May 19, 2011
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jae-Chun RYU, Youn Jung KIM, Mee SONG, Mi-Kyung SONG, Han Seam CHOI, Ji Hee KIM, Jina LEE
  • THERAPEUTIC COMBINATION COMPRISING AN AURORA KINASE INHIBITOR AND AN ANTINEOPLASTIC AGENT
    Publication number: 20110117212
    Abstract: The present invention provides a therapeutic combination comprising (a) compound 1 of formula (A) as set forth in the specification and (b) one or more antineoplastic agents selected from the group consisting of platinum derivatives, antimetabolite agents, topoisomerase I inhibitors and antimicrotubule agents, wherein the active ingredients are present in each case in free form or in the form of a pharmaceutically acceptable salt or any hydrate thereof.
    Type: Application
    Filed: July 3, 2009
    Publication date: May 19, 2011
    Applicant: NERVIANO MEDICAL SCIENCES S.R.L.
    Inventors: Enrico Pesenti, Maurizio D'Incalci, Dario Ballinari, Juergen Moll
  • PREPARATION METHOD FOR PtCo NANOCUBE CATALYST
    Publication number: 20110118111
    Abstract: The present invention features a method for preparing a PtCo nanocube catalyst, the method comprising dissolving a platinum (Pt) precursor, a cobalt (Co) precursor, a surface stabilizer and a reducing agent in a solvent to prepare a solution; heating the solution under an inert gas atmosphere; maintaining the temperature of the solution to obtain PtCo alloy nanocubes; adsorbing the PtCo alloy nanocubes on a carbon support to obtain a catalyst; and removing the surface stabilizer from the catalyst. The disclosed method for preparing a PtCo nanocube catalyst enables preparation of nanocubes with uniform size and cubic shape through a simple process and application for development of high-efficiency fuel cells by preventing change in shape, surface area and composition caused by agglomeration of the nanocubes.
    Type: Application
    Filed: July 20, 2010
    Publication date: May 19, 2011
    Applicants: HYUNDAI MOTOR COMPANY, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Inchul Hwang, Nak Hyun Kwon, Jae Seung Lee, Joon-Taik Park, Sang-Il Choi
  • SEPARATION REAGENT OF PLATINUM GROUP METAL, METHOD FOR SEPARATING AND RECOVERING PLATINUM GROUP METAL, AND AMIDE-CONTAINING TERTIARY AMINE COMPOUND
    Publication number: 20110113927
    Abstract: The present invention provides a novel separation reagent capable of obtaining a high extraction % of rhodium in a chlorine-based acid solution, which has never existed heretofore, and a method for separating and recovering a platinum group metal using the same. An organic phase composed of an amide-containing tertiary amine separation reagent represented by the structural formula shown below is brought into contact with an acid solution containing a platinum group metal, thereby extracting rhodium, platinum and palladium with the organic phase.
    Type: Application
    Filed: January 25, 2011
    Publication date: May 19, 2011
    Applicant: National Institute of Advanced Industrial Science and Technology
    Inventors: Hirokazu NARITA, Mikiya TANAKA, Kazuko MORISAKU
  • APPARATUS AND METHOD FOR BALANCING COLOR OF FLASHED IMAGE USING DEPTH ESTIMATION
    Publication number: 20110115941
    Abstract: Disclosed herein is an apparatus and method for balancing the color of a flashed image using depth estimation. The apparatus includes a depth value measurement unit, a region identification unit, a color impression estimation unit, and a color balancing unit. The depth value measurement unit measures the depth values of the respective regions of an image to be captured using a camera preview image. The region identification unit identifies the regions of the preview image as a region influenced by camera flash or a region not influenced by camera flash using the depth values measured by the depth value measurement unit. The color impression estimation unit estimates the color impression of actual illumination in the region not influenced by camera flash. The color balancing unit corrects the color of the region influenced by camera flash.
    Type: Application
    Filed: December 29, 2009
    Publication date: May 19, 2011
    Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Seong Dae Kim, Sung Soo Hwang, Su Jung Kim, Hwang Soo Lee, Young Serk Shim, Joon Sik Choi
  • MICROFLUIDIC DROPLET GENERATION AND/OR MANIPULATION WITH ELECTRORHEOLOGICAL FLUID
    Publication number: 20110114190
    Abstract: The subject disclosure relates to microfluidic devices, systems and methodologies that facilitate generation of droplets, control, and/or manipulation thereof with electrorheological (ER) fluids. In one aspect, ER fluids can be employed with a carrier fluid or as a carrier fluid to enable droplet generation, control, and/or manipulation. As a further advantage, embodiments of the disclosed subject matter can include droplet generation, control, and/or manipulation for liquids, gases, combinations, etc. Further non-limiting embodiments are provided that illustrate the advantages and flexibility of the disclosed structures.
    Type: Application
    Filed: November 16, 2010
    Publication date: May 19, 2011
    Applicant: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Weijia Wen, Ping Sheng, Xize Niu, Mengying Zhang, Jinbo Wu
  • SOMATIC EMBRYOGENESIS OF JATROPHA CURCAS FROM OVULES
    Publication number: 20110117652
    Abstract: The present invention relates to the field of somatic embryo production, particularly to methods for somatic embyrogenesis of Jatropha from ovules. More specifically, the present invention relates to a method and media compositions for somatic embryogenesis of Jatropha curcas from ovules of unopened flower buds. The method is well suited for Jatropha curcas transformation, for producing clonal planting stock useful for large scale Jatropha curcas plantation and for producing haploids, double haploids, diploids and disease-free plantlets.
    Type: Application
    Filed: June 18, 2009
    Publication date: May 19, 2011
    Applicant: TEMASEK LIFE SCIENCES LABORATORY LIMITED
    Inventors: Ramesh Anbazhagan Vasudevan, Srinivasan Ramachandran
  • DETECTION AND PROGNOSIS OF LUNG CANCER
    Publication number: 20110117551
    Abstract: Methods and tools are provided for detecting and predicting lung cancer. The methods and tools are based on epigenetic modification due to methylation of genes in lung cancer or pre-lung cancer. The tools can be assembled into kits or can be used seperately. Genes found to be epigentically silenced in association with lung cancer include ACSL6, ALS2CL, APC2, ART-S1, BEX1, BMP7, BNIP3, CBR3, CD248, CD44, CHD5, DLK1, DPYSL4, DSC2, EDNRB, EPB41L3, EPHB6, ERBB3, FBLN2, FBN2, FOXL2, GNAS, GSTP1, HS3ST2, HPN, IGFBP7, IRF7, JAM3, LOX, LY6D, LY6K, MACF1, MCAM, NCBP1, NEFH, NID2, PCDHB15, PCDHGA12, PFKP, PGRMC1, PHACTR3, PHKA2, POMC, PRKCA, PSEN1, RASSF1A, RASSF2, RBP1, RRAD, SFRP1, SGK, SOD3, SOX17, SULF2, TIMP3, TJP2, TRPV2, UCHL1, WDR69, ZFP42, ZNF442, and ZNF655.
    Type: Application
    Filed: February 19, 2009
    Publication date: May 19, 2011
    Applicants: ONCOMETHYLOME SCIENCES SA, THE JOHNS HOPKINS UNIVERSITY
    Inventors: Wim Van Criekinge, Josef Straub, Geert Trooskens, Stephen Baylin, James Herman, Kornel Schuebel, Leslie Cope, Leander Van Neste
  • MUTATED SALMONELLA TYPHI STRAIN AND USE THEREOF IN A VACCINE
    Publication number: 20110117132
    Abstract: The present invention relates to an attenuated Salmonella typhi having mutation in chromosomal gene loci, its use as a potent vaccine candidate to combat the Salmonella infection.
    Type: Application
    Filed: August 22, 2008
    Publication date: May 19, 2011
    Applicant: Indian Institute of Science
    Inventors: Dipshikha Chakravortty, Vidya Devi Negi