Abstract: The present disclosure provides poly(alkyloxazoline)-lipid conjugates, lipid particles comprising such conjugates, and methods of administering the lipid particles for nucleic acid delivery to cells or subjects.

Abstract: A high throughput fractionated satellite (HTFS) system and method where the functional capabilities of a conventional monolithic spacecraft are distributed across many small or very small satellites and a central command and relay satellite, the satellites are separated and flight in carefully design formations that allows the creation of very large aperture or apertures in space drastically reducing cost and weight and enabling high throughput capabilities by spatially reuse spectrum.

Abstract: The transplant fish production method includes selecting a donor fish species, selecting first and second fish species which are a combination that could be sterile, producing a hybrid fish species of the selected first fish species and second fish species, and transplanting reproductive cells of the donor fish species into the produced hybrid fish species.

Abstract: An example of a digital artery blood pressure monitor may include a tactile sensor array disposed on an inner surface of a cuff, the tactile sensor array including a plurality of capacitive sensors to detect pressure changes within a digital artery of a finger due to blood flow, where the pressure changes cause changes to capacitance values of one or more capacitive sensors of the tactile sensor array, and control circuitry coupled to the tactile sensor array to receive the capacitance values from the tactile sensor array, and determine a blood pressure based on the capacitance values.

Abstract: Disclosed embodiments relate to a convolutional neural network computing method and system based on weight kneading, comprising: arranging original weights in a computation sequence and aligning by bit to obtain a weight matrix, removing slack bits in the weight matrix, allowing essential bits in each column of the weight matrix to fill the vacancies according to the computation sequence to obtain an intermediate matrix, removing null rows in the intermediate matrix, obtain a kneading matrix, wherein each row of the kneading matrix serves as a kneading weight; obtaining positional information of the activation corresponding to each bit of the kneading weight; divides the kneading weight by bit into multiple weight segments, processing summation of the weight segments and the corresponding activations according to the positional information, and sending a processing result to an adder tree to obtain an output feature map by means of executing shift-and-add on the processing result.

Abstract: An active mattress encasement which can be relatively easily installed or removed or rotated over a mattress supported by a foundation is disclosed. The encasement is formed to encapsulate a mattress and may include a top panel, a bottom panel and multiple side panels. One or more of the side panels are zippered together. An inflatable volume is formed at least in part from at least a portion of the bottom panel. The inflatable volume includes an air inlet configured to be in communication with an external air supply that delivers air into the inflatable volume. The inflatable volume also includes one or more air discharge holes configured to discharge air from the inflatable volume.

Abstract: The present disclosure relates to a field of dry etching technology. The present disclosure provides an ultra-large area scanning reactive ion etching machine and an etching method thereof. The ultra-large area scanning reactive ion etching machine includes: an injection chamber, an etching reaction chamber, a transition chamber, and an etching ion generation chamber. By moving a sample holder among the injection chamber, the etching reaction chamber and the transition chamber in a scanning direction, a scanning etching is performed on a sample placed on the sample holder, which may realize a large-area, uniform and efficient etching.

Abstract: Exemplary positioning method and apparatus, a device, a system, a medium and a self-driving vehicle are provided. The positioning method includes determining, according to the current frame of point cloud data collected by a to-be-positioned terminal in a travelling environment, the current key point in the current frame of point cloud data and a point cloud distribution feature of the current key point; selecting, according to point cloud distribution features associated with reference key points in a global positioning map and the point cloud distribution feature of the current key point, a target key point matching the current key point from the reference key points; and determining, according to reference pose data associated with the target key point, the current pose data of the to-be-positioned terminal.

Abstract: Provided herein are a method for isolation and transplantation of intact mitochondria to a lymphoid organ (a primary lymphoid tissue or a secondary lymphoid tissue), a composition of cells prepared by using a method described herein, and a method for manufacturing cells described herein. In particular, provided herein are methods of isolating intact mitochondria from a donor cell. Also provided herein are methods of transplanting mitochondria into a recipient cell. In some aspects, the methods can be performed in vivo. Further provided are a composition of cells that include the cells prepared using the methods of the present invention.

Abstract: Provided is a Raman-active particle which is a Raman-active particle for surface-enhanced Raman analysis, the particle including: a spherical plasmonic metal core; a plasmonic metal shell having surface unevenness; and a self-assembled monolayer which is bonded to each of the core and the shell and positioned between the core and the shell, and includes a Raman reporter.

Abstract: A cell culture instrument configured to detach cells at a desired position and a cell processing method using the cell culture instrument. The cell culture instrument includes: a substrate; and a photoreactive layer having a photosolubility and a photothermal convertibility, wherein the photoreactive layer is laminated on the substrate, and the photoreactive layer includes a polymer having a photosolubility and a photothermal convertibility.

Abstract: The present invention relates to the technical field of power generation of power systems, and in particular to a power supply and energy storage system using carbon as a medium. The power supply and energy storage system generates energy by reacting carbon dioxide and air, collects carbon monoxide by providing a pressurizing apparatus and a gas storage apparatus, and sends the collected carbon monoxide back to an energy supply apparatus during power consumption peaks, thereby balancing power deficits of loads and renewable energy power generation, considering the stability, reliability, and economic efficiency of the power supply and energy storage system, and improving energy utilization efficiency.

Abstract: The present disclosure provides methods for inhibiting entry of a virus into a host cell using picolinic acid or a salt or derivative thereof. The present disclosure also provides methods for treating or preventing a viral infection in a subject by administering picolinic acid or a salt or derivative thereof. In particular, the methods of the present disclosure are effective for enveloped viruses and syncytium-forming viruses. In some embodiments, the present disclosure provides methods of treating or preventing a SARS CoV-2, Influenza A virus, human parainfluenza virus, herpes simplex virus, Japanese encephalitis virus, Zika virus, or a flavivirus infection.

Abstract: The present invention relates to useful methods of treating Acute Myeloid Leukemia (AML) in a human. in the presence of gene mutations.

Abstract: An easy-to-assemble mounting rack for a deformation detection device for a steel structure and an assembling method thereof are provided. The easy-to-assemble mounting rack includes mounting parts including a back mounting plate, an operating rod, an adjusting seat, a ball-shaped block and an upright rod. The upright rod is vertically fixed at the bottom end face of the adjusting seat. A ball-shaped hole is formed in the adjusting seat. The ball-shaped block is rotatably embedded in the ball-shaped hole. A plug-in hole is formed in a radial direction of the ball-shaped block. One end of the operating rod slidably penetrates through the plug-in hole and is detachably connected with the back mounting plate. Screw holes directly opposite to the mounting holes of the deformation detection device are formed on the back mounting plate. The other end of the operating rod is fixedly sleeved with a counterweight plate.

Abstract: A system and method for quantile-based assessment and handling of digital events in a digital threat mitigation platform includes receiving, via an application programming interface (API), a request from a subscriber to assess a threat of a digital event, computing, using one or more threat scoring machine learning models, a digital threat inference based on one or more corpora of feature vectors associated with the digital event, wherein the digital threat inference includes an uncalibrated digital threat score, retrieving, from a database, a T-Digest data structure of historical digital threat scores of the subscriber, computing, using the T-Digest data structure of historical digital threat scores, a percentile-based threat score based on the uncalibrated digital threat score computed for the digital event, and executing an automated disposal decision computed for the digital event based on at least the percentile-based threat score satisfying automated decisioning instructions of the digital threat mitiga

Abstract: The present disclosure discloses a water recycling type greenhouse, including a greenhouse body; a water collection device is arranged in the greenhouse body; the water collection device is provided with an air inlet and an air outlet; a condensation portion and a reheating portion are arranged in the water collection device; and the water recycling type greenhouse further includes an energy supply system. Air in the greenhouse body can be poured into the water collection device from the air inlet, flow through the condensation portion and the reheating portion in sequence, and finally be discharged into the greenhouse body again from the air outlet. When the heated air is discharged into the greenhouse body again, a decrease of the temperature of the greenhouse is not likely to occur, and normal growth of plants is not easily affected.

Abstract: The present disclosure provides a high-entropy rare earth-toughened tantalate ceramic. The ceramic is prepared by sintering Ta2O5 powder and x types of different RE2O3 powder, 4?x?9, and the molar ratio of the RE2O3 powders is 1. RE2O3 powder and Ta2O5 powder having the molar ratio of RE to Ta being 1:1 are weighed, a solvent is added for mixing, and ball milling is performed by a ball mill to obtain mixed powder M; the powder M is dried at a temperature of 650-850° C. for 1.5-2 h to obtain dried powder; the powder is sieved to obtain powder N, the powder N is placed in a mold for first pressing to obtain a rough blank, and the rough blank is then pressed for the second time to obtain a compact blank; the compact blank is sintered to obtain the high-entropy rare earth-toughened tantalate ceramic.

Abstract: Provided herein are methods of generating models for predicting the glycemic response of an individual to consumption of a food or meal. The method involves collecting from a plurality of subjects, phenotypic data, ohmic data, and glycemic response data to foods or meals having a defined macronutrient profile. This data is then used to train a machine learning algorithm to create a model that predicts glycemic response of an individual to a food or meal based on the macro nutrient profile of the food or meal.

Abstract: Compounds and methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.