Patents Assigned to Sciences
  • Patent number: 6929921
    Abstract: The present invention relates to a novel member of the blue-light photoreceptor family of receptors. In particular, isolated nucleic acid molecules are provided encoding the human hCRY2 receptor. hCRY2 polypeptides are also provided as are vectors, host cells, antibodies, and recombinant methods for producing the same.
    Type: Grant
    Filed: April 15, 2003
    Date of Patent: August 16, 2005
    Assignees: Human Genome Sciences, Inc., The University of North Carolina at Chapel Hill
    Inventors: Ying-Fei Wei, Steven M. Ruben, Aziz Sancar, Shiao-Wen D. Hsu, Aleksey G. Kazantsev
  • Patent number: 6930399
    Abstract: The method of the present invention comprises the steps of: providing an IC chip having I/O pads, each having a non-solder bump such as Au or Cu stud bump or Ni\Cu\Au bump formed thereon, and a substrate having metal electrodes formed thereon; applying a film-type non-conductive adhesive (NCA) to the chip or substrate, the adhesive including solid-phase bisphenol A type epoxy resin, liquid-phase bisphenol F type epoxy resin, solid-phase phenoxy resin, methylethylketone/toluene solvent, liquid-phase hardener, and non-conductive particles; and thermo-compressing the IC chip to the substrate so that the non-solder bump and the metal electrode can be mechanically and electrically connected. The NCA of the present invention has high reliability since it has lower thermal expansion coefficient and dielectric constant than conventional NCAs and has excellent mechanical and electrical characteristics.
    Type: Grant
    Filed: August 2, 2001
    Date of Patent: August 16, 2005
    Assignees: Korea Advanced Institute of Science and Technology, Telephus Inc.
    Inventors: Kyung-Wook Paik, Myung-Jin Yim
  • Patent number: 6928873
    Abstract: A silicon dual inertial sensor made of a (110) silicon chip comprises at least a proof-mass, which is connected to a corresponding inner frame with a plurality of sensing resilient beams to make it easier for the proof-mass to move perpendicular to the surface of the silicon chip (defined as z-axis), and each inner frame is connected to an outer frame with a plurality of driving resilient beams, or connected to common connection beams, which are then connected to a central anchor with common resilient supporting beams to make it easier for the inner frame to move in parallel with the surface of the silicon chip (defined as y-axis). Each inner frame is driven by a driver to move in an opposite direction along the y-axis, and also move the proof-mass in the opposite direction along the y-axis. If there is a rotation rate input along the x-axis, it will generate a Coriolis force to make each proof-mass move in the opposite direction of the z-axis.
    Type: Grant
    Filed: November 1, 2003
    Date of Patent: August 16, 2005
    Assignee: Chung-Shan Institute Of Science And Technology
    Inventors: Shyu-Mou Chen, Sheau-Shi Tzuoo, Chung-Ta Kau
  • Publication number: 20050176044
    Abstract: Receptor polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing receptor polypeptides and polynucleotides in the design of protocols for the treatment of diseases and diagnostic assays for such conditions.
    Type: Application
    Filed: January 25, 2005
    Publication date: August 11, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Craig Rosen, Reiner Gentz
  • Publication number: 20050174128
    Abstract: A capacitance-type fingerprint sensor. The capacitance-type fingerprint sensor includes a plurality of pixel groups, each of which electrically connects a plurality of sensing electrodes to a plurality of coupling electrodes, respectively; a plurality of first sensing-electrode switches for connecting the sensing electrodes to a voltage source; a plurality of second sensing-electrode switches for interconnecting the sensing electrodes contained in the pixel groups; a plurality of third sensing-electrode switches for interconnecting the pixel groups; and a plurality of coupling-electrode switches for interconnecting the coupling electrodes contained in all pixel groups. Therefore, the fingerprint sensor blocks or corrects capacitance generated by internal components of a fingerprint sensor, such that it acquires a high-quality fingerprint image.
    Type: Application
    Filed: December 22, 2004
    Publication date: August 11, 2005
    Applicant: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Seong-Jin Kim, Euisik Yoon
  • Publication number: 20050177031
    Abstract: Systems and methods for evaluating the effectiveness of a person to perform a task based on his/her preceding or predicted sleep pattern are provided. An interface allows a user to use actual sleep data or predicted sleep data to produce predictions of the task effectiveness of a person to perform a particular task. The predictions may be in tabular, graphical, or tabular and graphical format. The interface may also represent the effectiveness of a user based on the actual or predicted sleep data in conjunction with an actual or predicted work schedule or pattern. The results can be correlated to sunlight in the user's location, and can also account for changes in the users location (transmeridian shifts), sunlight during the user's sleep cycle (shift work), and other schedule modifying events.
    Type: Application
    Filed: January 11, 2005
    Publication date: August 11, 2005
    Applicant: Science Applications International Corporation
    Inventor: Steven Hursh
  • Publication number: 20050176093
    Abstract: Disclosed is a method of analyzing mass of the phosphoproteins or phosphopeptides and of analyzing phosphorylated positions at a phosphoprotein or phosphopeptide, comprising the steps of: 1) dephosphorylating at least one Ser and/or Thr residue of the phosphoprotein or phosphopeptide; 2) tagging the dephosphorylated amino acid residues with a tag having a R-L-G moiety wherein R is a nucleophilic functional group that selectively bind with dephosphorylated amino acid residues, G is selected from the group consisting of guanidine moiety or protected guanidine moiety such as a mono-N-protected guanidino group, a di-N,N?-protected guanidino group and an N?-protected guanidino group, and L is a linker linking the R and the G; and 3) subjecting the tagged proteins or peptides to mass spectrometry. The method is capable of precisely analyzing mass of phosphoproteins of trace amounts as well as positions of phosphoryated amino acids.
    Type: Application
    Filed: April 21, 2005
    Publication date: August 11, 2005
    Applicant: KOREA BASIC SCIENCE INSTITUTE
    Inventors: Yeong Hee AHN, Jong Shin YOO, Jin Young KIM, Kun CHO
  • Publication number: 20050176943
    Abstract: The present invention provides a group of mouse spermatogenesis genes, which is an assembly of 89 genes in total, wherein the respective genes transcribe mRNAs from which cDNAs having the respective base sequences of SEQ ID NOs:1 to 89 are synthesized; an Scot-t gene mutation and a protamine-2 gene mutation which are human homologues of genes belonging to the group of mouse genes and associated with human male infertility. The invention also provides a group of mouse spermatogenesis genes and various molecular biological materials relating thereto; various molecular biological materials relating to male infertility-associated gene mutations; and various test methods and diagnostic methods using the same.
    Type: Application
    Filed: February 14, 2003
    Publication date: August 11, 2005
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Yoshitake Nishimune, Hiromitsu Tanaka, Masami Nozaki
  • Publication number: 20050175788
    Abstract: The present invention provides a method for manufacturing a titanium dioxide photocatalyst composite material, and relates to a method for manufacturing a titanium dioxide composite ceramic material on which photoactive (photooxidative) apatite or another calcium phosphate monocrystal is partially deposited, wherein the method is characterized in promoting the following reactions by immersing titanium dioxide in an aqueous solution containing an excess of phosphorus ions and calcium ions in comparison with an artificial body fluid in order to fabricate a titanium dioxide photocatalyst composite material on which a compound composed of one or more apatite or other calcium phosphate Ca9(PO4)6 monocrystals is partially deposited: (1) forming and aggregating calcium phosphate clusters and producing octacalcium phosphate; (2) converting the octacalcium phosphate into an apatite or other calcium phosphate Ca9(PO4)6 monocrystal; and (3) growing the monocrystal.
    Type: Application
    Filed: June 5, 2003
    Publication date: August 11, 2005
    Applicant: NAT INSTTITUTE OF ADVANCED INDUST SCIENCE & TECH
    Inventor: Toru Nonami
  • Publication number: 20050176095
    Abstract: This invention provides a transcription factor that has functions of regulating the expression of a sulfur-assimilatory gene of koji mold during culture, and a gene encoding the same. This invention also relates to a protein comprising the amino acid sequence as shown in SEQ ID NO: 3, and a gene encoding the amino acid sequence as shown in SEQ ID NO: 3 or comprising the nucleotide sequence as shown in SEQ ID NO: 2.
    Type: Application
    Filed: August 20, 2002
    Publication date: August 11, 2005
    Applicants: NODA INSTITUTE FOR SCIENTIFIC RESEARCH, NAT. INST. OF ADVANCED INDUSTR. SCIENCE AND TECH.
    Inventors: Genryou Umitsuki, Osamu Hatamoto, Seiichi Hara, Tsutomu Masuda, Motoaki Sano, Masayuki Machida
  • Publication number: 20050176103
    Abstract: Disclosed are human VEGF2 polypeptides, biologically active, diagnostically or therapeutically useful fragments, analogs, or derivatives thereof, and DNA (RNA) encoding such VEGF2 polypeptides. Also provided are procedures for producing such polypeptides by recombinant techniques and antibodies and antagonists against such polypeptides. Such polypeptides may be used therapeutically for stimulating wound healing and for vascular tissue repair. Also provided are methods of using the antibodies and antagonists to inhibit tumor angiogenesis and thus tumor growth, inflammation, diabetic retinopathy, rheumatoid arthritis, and psoriasis.
    Type: Application
    Filed: February 28, 2005
    Publication date: August 11, 2005
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jing-Shan Hu, Craig Rosen, Liang Cao
  • Publication number: 20050176071
    Abstract: The present invention provides a method of assaying for kinase activity, comprising contacting a fluorescently labeled phosphorylatable peptide substrate with an ATP analog in the presence of a kinase enzyme to yield a first product; contacting the first product with a reactant that comprises a biotin derivative to yield a second product; contacting the second product with a biotin-binding protein; and detecting a difference in a fluorescence polarization level from the second product as compared to a fluorescence polarization of the peptide substrate.
    Type: Application
    Filed: May 27, 2004
    Publication date: August 11, 2005
    Applicant: Caliper Life Sciences, Inc.
    Inventors: Theo Nikiforov, Sang Jeong
  • Patent number: 6926831
    Abstract: In order to provide a safe means for the direct purification of groundwater, which enables the efficient use of carbon source and the concentration of nitrificans, while requiring no addition of heavy metals, a starch-derived biodegradable plastic is used as a single carbon source and immobilizing carrier of denitrificans, and contacted with nitrate-polluted groundwater.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: August 9, 2005
    Assignee: Japan Science and Technology Corporation
    Inventors: Masatoshi Matsumura, Rey Nayve Fidel
  • Patent number: 6927997
    Abstract: The present invention relates to an OTP ROM using a CMOS gate oxide antifuse.
    Type: Grant
    Filed: June 14, 2004
    Date of Patent: August 9, 2005
    Assignee: Korea Advance Institute of Science and Technology
    Inventors: Kwyro Lee, Jinbong Kim, Hyouk-Kyu Cha
  • Patent number: 6926927
    Abstract: A chalcogen film is applied to an acute tip of a glass fiber and the acute tip is held in physical contact with a metal layer so as to induce diffusional reaction for generation of a metal chalcogenide nano-particle or nano-particles at the acute tip. In the case where the chalcogen film is directly applied to the acute tip, the generated nano-particle or nano-particles are transferred from the acute tip to a corresponding part of the metal layer. When a silane-adsorbed film is pre-formed on the acute tip before application of the chalcogen film, the generated nano-particle or nano-particles are fixed to the acute tip. The nano-particles are several to tens in number with very narrow distribution of particle size. Since particle size and fixed position of the nano-particle or nano-particles can be controlled with high freedom, the nano-particle or nano-particles are useful as a light-emitting or photo-detecting element.
    Type: Grant
    Filed: November 26, 2001
    Date of Patent: August 9, 2005
    Assignee: Japan Science and Technology Corporation
    Inventor: Akito Ishida
  • Patent number: 6928492
    Abstract: Multiple applications enable communications I/O operation and an I/O interface operations simultaneously at a low cost. The process A requests an OS to allocate an area where a request to an I/O device is put. The OS also allocates an unused context ID for the I/O device to the process A, maps a memory page corresponding to the context ID as an address for accessing the pending register for the process A, and stores a pointer (a physical address) to a request storing area of the process A into an embedded memory in the I/O device. The process A writes contents of requests in its own request storing area, and the OS notifies the I/O device that there is an unprocessed request by use of the address for the pending register. The I/O device reads out the contents of the request storing area by a DMA engine, and realizes the request.
    Type: Grant
    Filed: August 1, 2000
    Date of Patent: August 9, 2005
    Assignee: Japan Science and Technology Agency
    Inventor: Takashi Matsumoto
  • Patent number: 6927185
    Abstract: As-prepared AlPO4—B2O3—Na2O-based glasses were placed in an autoclave together with distilled water and were treated at 150° C. for two hours. Although the specific surface area of the as-prepared glass prior to autoclave treatment was negligibly small, the autoclave treatment dissolved most of the borate component and the sodium component to obtain a mesoporous material having a specific surface area of 236 m2/g and a pore size distribution of 5 to 10 nm. This mesoporous material is hydrophobic and has weak solid acidity and small polarity.
    Type: Grant
    Filed: January 11, 2002
    Date of Patent: August 9, 2005
    Assignee: Japan Science and Technology Corporation
    Inventors: Shoji Yamanaka, Toshiyuki Sasaki
  • Patent number: 6928600
    Abstract: A kind of folding systolic array architecture for a CFRS decoding circuit that applies to a cell search in a wideband code division multiple access system. The invention involves using a systolic array for its decoding circuit and using a kind of folding technology to reduce the area of the systolic array. The systolic array for the decoding circuit comprises an input pattern generator, a processing element array designed in the form of a systolic array and a boundary processing element array. Given the skewed-form output results required by the systolic array and generated by the input pattern generator, the processing element array makes a set of correlating comparisons, and outputs the results of the correlating comparisons to the boundary processing elements, so as to acquire the decoding results required by the CFRS decoding. The results indicate the frame boundary and scrambling code groups of the cell search in a wideband code division multiple access system.
    Type: Grant
    Filed: April 16, 2002
    Date of Patent: August 9, 2005
    Assignee: Chung Shan Institute of Science and Technology
    Inventors: Chi-Fang Li, Wern-Ho Sheen, Yuan-Sun Chu, Jan-Shin Ho, Yuan-Tzu Ting
  • Patent number: 6927288
    Abstract: Th inventions of this application include thermogenic genes named SfUCPa and SfUCPb which are derived from skunk cabbage. cDNA of each gene comprises the base sequence of SEQ ID NO: 1 and 3, respectively. Thermogenic proteins, SfUCPA and SfUCPB, are expressed from genes SfUCPa and SfUCPb, comprises the amino acid sequence of SEQ ID NO: 2 and 4.
    Type: Grant
    Filed: September 29, 2003
    Date of Patent: August 9, 2005
    Assignee: Japan Science and Technology Corporation
    Inventor: Kikukatsu Ito
  • Patent number: 6926898
    Abstract: The present invention encompasses albumin fusion proteins. Nucleic acid molecules encoding the albumin fusion proteins of the invention are also encompassed by the invention, as are vectors containing these nucleic acids, host cells transformed with these nucleic acids vectors, and methods of making the albumin fusion proteins of the invention and using these nucleic acids, vectors, and/or host cells. Additionally the present invention encompasses pharmaceutical compositions comprising albumin fusion proteins and methods of treating, preventing, or ameliorating diseases, disordrs or conditions using albumin fusion proteins of the invention.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: August 9, 2005
    Assignee: Human Genome Sciences, Inc.
    Inventors: Craig A. Rosen, William A. Haseltine