Patents Assigned to Sciences
  • Patent number: 6771237
    Abstract: Disclosed are cross-talk resistant drive circuitry for electrostatic video displays and flexible, foldable and shaped embodiments of such displays including books, fanfolds and scrolls employing flexible polymer film construction. Transistorless drive circuitry uses row and column dumping capacitors to charge electrostatic pixels in a traveling group to avoid simultaneously charging row-adjacent pixels. Also, individual pixels can be shielded each with their own Faraday cage to control charge leakage from the pixel. The pixels' have spiral rollout shutters whose time parameters can be controlled by the use of suitable bleed resistors. Low-cost film technology manufacturing methods are also described.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: August 3, 2004
    Assignee: Display Science, Inc.
    Inventor: Charles G. Kalt
  • Patent number: 6770466
    Abstract: The present invention relates to novel human PTPase polypeptides and isolated nucleic acids containing the coding regions of the genes encoding such polypeptides. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human PTPase polypeptides. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human PtPase polypeptides.
    Type: Grant
    Filed: July 18, 2001
    Date of Patent: August 3, 2004
    Assignee: Human Genome Sciences, Inc.
    Inventors: Yanggu Shi, Steven M. Ruben
  • Patent number: 6770585
    Abstract: The present invention provides a process to extract oil from Momordica cochinchinensis aril to yield an edible oil rich in &bgr;-carotene. The process can be carried out without the use of any harmful organic solvents, and provides products containing other carotenoids, such as lycopene, and fiber and vitamin E. This invention provides a bioavailable and stable source of &bgr;-carotene, a pro-vitamin A carotenoid, in areas where vitamin A deficiency exists. Products derived from this invention serve as a safe source of antioxidants and nutritional supplement for human and animal consumption, and for the pharmaceuticals and cosmetics industries as well as providing a suitable, effective food additives and colorants.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: August 3, 2004
    Assignee: Vitalea Science, Inc.
    Inventor: Le Thuy Vuong
  • Patent number: 6770454
    Abstract: The specification relates to a method for the detection and collection of samples of microorganisms, such as mold spores, from the air and from surfaces utilizing a collection device that employs a substantially dry growth medium which is hydrated by a premeasured volume of liquid after microorganism collection on the dry growth medium has occurred. The specification also relates to a microorganism collection and detection kit comprising a microorganism collection device having a substrate and a layer of dry growth medium applied thereon, and a container of a premeasured volume of hydrating liquid.
    Type: Grant
    Filed: April 4, 2001
    Date of Patent: August 3, 2004
    Assignee: Home Health Science Inc.
    Inventors: Sean M. Reilly, Paul T. LaRocca, Mary Anne Kunz LaRocca
  • Publication number: 20040146893
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: October 15, 2003
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Paul E. Young, John M. Greene, Jian Ni, Ping Feng, Kimberly A. Florence, Jing-Shan Hu, Ann M. Ferrie, Guo-Liang Yu, Roxanne D. Duan, Fouad Janat
  • Publication number: 20040148103
    Abstract: A grid terrain data collision detecting method for forward looking terrain avoidance comprising the following steps: the use of kinematics equation to analytically find out sampling points positions; processing the sampling points in sequence with time increments; and using function minimum value theory to detect collision with results obtained from the sampling point process step.
    Type: Application
    Filed: January 15, 2003
    Publication date: July 29, 2004
    Applicant: Chung-Shan Institute of Science and Technology
    Inventors: Day-Woei Chiuo, Kuang-Peng Ho, Shin-Jen Chen
  • Publication number: 20040146551
    Abstract: The present invention provides geodate delivery vehicles and methods of manufacture and administration. A vehicle including a lipid monolayer disposed about a hydrophobic domain is disclosed, that can be part of an emulsion or other mixture, or further disposed in a lipid strata. A vehicle including a lipid strata disposed about a hydrophobic domain is also disclosed. The vehicle can be incorporated into a variety of medicinal, food preparations, and personal care products to deliver or stabilize a cargo moiety. Packaged delivery vehicles for later addition of cargo moieties are also contemplated.
    Type: Application
    Filed: November 3, 2003
    Publication date: July 29, 2004
    Applicant: BioDelivery Sciences International, Inc.
    Inventors: Raphael J. Mannino, Sara L. Krause-Elsmore, Susan Gould-Fogerite, David Delmarre, Ruying Lu
  • Publication number: 20040146510
    Abstract: The present invention discloses transforming growth factor alpha HII polypeptides and polynucleotides encoding such polypeptides. Also provided is a procedure for producing such polypeptides by recombinant techniques and therapeutic uses of the polypeptides which include stimulating wound healing, treating neurological disorders, treating ocular disorders, treating kidney and liver disorders, and stimulating embryogenesis and angiogenesis. Also disclosed are antagonists against such polypeptides and their use as a therapeutic to treat neoplasia. Also disclosed are diagnostic assays for detecting altered levels of the polypeptide of the present invention and mutations in the nucleic acid sequences which encode the polypeptides of the present invention.
    Type: Application
    Filed: August 21, 2003
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Ying-Fei Wei, Paul S. Meissner, Jian Ni
  • Publication number: 20040146927
    Abstract: Disclosed is a human Fibroblast growth factor-14 polypeptide and DNA(RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques. Also disclosed are methods for utilizing such polypeptide for promoting wound healing for example as a result of burns and ulcers, to prevent neuronal damage due to associated with stroke and promote neuronal growth, and to prevent skin aging and hair loss, to stimulate angiogenesis, mesodermal induction in early embryos and limb regeneration. Antagonists against such polypeptides and their use as a therapeutic to prevent abnormal cellular proliferation, hyper-vascular diseases and epithelial lens cell proliferation are also disclosed. Diagnostic methods for detecting mutations in the coding sequence and alterations in the concentration of the polypeptides in a sample derived from a host are also disclosed.
    Type: Application
    Filed: February 27, 2004
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: John M. Greene, Patrick J. Dillon
  • Publication number: 20040146501
    Abstract: The present invention concerns a novel T1R-like ligand II protein. In particular, isolated nucleic acid molecules are provided encoding the T1R-like ligand II protein. T1R-like ligand II polypeptides are also provided, as are recombinant vectors and host cells for expressing the same.
    Type: Application
    Filed: October 27, 2003
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Reiner L. Gentz, Steven M. Ruben
  • Publication number: 20040147733
    Abstract: The present invention relates to four novel Fc receptor-like proteins which are members of the Fc Receptor family. In particular, isolated nucleic acid molecules are provided encoding the human FcR-I, FcR-II, FcR-III, and FcR-IV proteins. FcR-I, FcR-II, FcR-III, and FcR-IV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of FcR-I, FcR-II, FcR-III, and FcR-IV activities. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.
    Type: Application
    Filed: February 5, 2004
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Henrik S. Olsen, Jian Ni, Marianne Murphy, Steven M. Ruben, Reiner L. Gentz
  • Publication number: 20040147597
    Abstract: The present invention relates to compounds, compositions and methods for the prevention or treatment of mycobacterium infections. The compounds are naturally occurring and synthetic biflavonoids, flavonoids, chalcones and chalcone like compounds. The compounds were screened for anti-mycobacterium activity. Of the compounds showing anti-mycobacterium activity, eight were identified as particularly potent, exhibiting greater than 90% inhibition of the growth of Mtb at a concentration of 12.5 Πg/mL. The actual minimum inhibitory concentrations (MIC), defined as the lowest concentration inhibiting 99% of the inoculum, for the preferred compounds ranged from 6.8 to 48.3 ΠM.
    Type: Application
    Filed: January 12, 2004
    Publication date: July 29, 2004
    Applicant: Advanced Life Sciences, Inc.
    Inventor: Yuh-Meei Lin
  • Publication number: 20040147716
    Abstract: Disclosed are D-peptides and libraries of D-peptides comprising aromatic D-amino acids. Also disclosed are methods for identifying small D-peptides comprising aromatic D-amino acids that bind to proteins of interest.
    Type: Application
    Filed: July 2, 2003
    Publication date: July 29, 2004
    Applicant: Bio Science International, Inc.
    Inventor: Byron E. Anderson
  • Publication number: 20040146585
    Abstract: The present invention provides methods for preventing or reducing chemotherapeutic agent-induced thrombocytopenia. These methods comprise administering an effective amount of a thiol-containing compound or composition (e.g., sodium thiosulfate and N-acetylcysteine) to a subject in need thereof.
    Type: Application
    Filed: October 31, 2003
    Publication date: July 29, 2004
    Applicant: Oregon Health & Science University
    Inventors: Edward A. Neuwelt, Leslie L. Muldoon
  • Publication number: 20040146930
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating disorders related to these novel human secreted proteins.
    Type: Application
    Filed: March 16, 2004
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Jian Ni, Craig A. Rosen, Ying-Fei Wei, Paul Young, Kimberly Florence, Daniel R. Soppet, Laurie A. Brewer, Gregory A. Endress, Kenneth C. Carter, Michael Mucenski, Reinhard Ebner, David W. LaFleur, Henrik Olsen, Yanggu Shi, Paul A. Moore, George Komatsoulis
  • Publication number: 20040146013
    Abstract: A time division duplex repeater system includes two antennas, a switched directional amplifier and control circuitry. The antennas serve first and second coverage areas where the second coverage area is an extension of the first coverage area. The switched directional amplifier is coupled between the two antennas and has a single amplifier. The control circuitry is coupled to the switched directional amplifier and to receive inputs of the antennas. The control circuitry receives transmissions from the coverage areas and applies control signals to the switched directional amplifier to control the direction of transmission. The control circuitry may control the amplifier gain and direction of transmission based on the input signal power level.
    Type: Application
    Filed: January 22, 2003
    Publication date: July 29, 2004
    Applicant: Hong Kong Applied Science and Technology Research Institute Co., Ltd
    Inventors: Peter Chun Teck Song, Ross David Murch, Hang Ching Jason Leung, Wai Yuk William Tao
  • Publication number: 20040146928
    Abstract: A human F-spondin-like protein and DNA (RNA) encoding such protein and a procedure for producing such protein by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for treating spinal cord injuries and damage to peripheral nerves by promoting neural-cell adhesion and neurite extension, inhibiting tumor metastases and tumor angiogenesis, and stimulating wound repair. Antagonists are also disclosed which may be utilized to prevent malaria. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed.
    Type: Application
    Filed: March 1, 2004
    Publication date: July 29, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Gregg Hastings, Patrick J. Dillon
  • Patent number: 6768407
    Abstract: A permanent-magnet-type magnetic field generator (10) capable of generating a strong magnetic field not weaker than 3 T in a magnetic field generation space (12) is provided. The magnetic field generator (10) has an axially central portion serving as the magnetic field generation space (12), and includes a first magnetic circuit (14) provided by a Halbach array at an outer central portion, and a second magnetic circuit (16) formed inside the first magnetic circuit (14) to surround the magnetic field generation space (12). The first magnetic circuit (14) is provided by permanent magnets (20a)-(20f) and central portions (A) of permanent magnets (22a)-(22f). The second magnetic circuit (16) is provided by a pair of pole pieces (24a) and (24b) each having a saturation magnetism not smaller than 1.6 T, and central portions (B) of permanent magnets (26a)-(26d) which provides magnetic interconnection between the pole pieces (24a) and (24b).
    Type: Grant
    Filed: January 9, 2004
    Date of Patent: July 27, 2004
    Assignees: Sumitomo Special Metals Co., Ltd., National Institute of Radiological Sciences
    Inventors: Tsutomu Kohda, Masayuki Kumada
  • Patent number: 6768300
    Abstract: An apparatus for measuring electromagnetic characteristics includes a sample rod with a sample fixed to a lower part thereof, a helium 3 refrigerator, in which the sample rod is inserted, having a main pipe that forms around the sample rod a space that is cooled by helium 3, a device for supplying helium 3 to the helium 3 refrigerator, an inner tube portion, into which the main pipe is inserted, that supports at an upper part thereof the refrigerator, an outer tube that cools an outer periphery of the inner tube with helium, a liquid helium container that supplies liquid helium to the outer tube, and a device for measuring the electromagnetic characteristics of the sample.
    Type: Grant
    Filed: November 19, 2002
    Date of Patent: July 27, 2004
    Assignee: National Institute of Advanced Industrial Science and Technology
    Inventors: Naoki Shirakawa, Shinichi Ikeda
  • Patent number: 6768158
    Abstract: The present invention provides a flash memory element and its manufacturing method having improved overall memory characteristics by constituting a double-gate element for improving the scaling down characteristic of flash memory element. With the above double-gate flash memory structure, a flash memory element in the present invention improves the scaling down characteristic and the programming and retention characteristic of a flash memory element.
    Type: Grant
    Filed: September 4, 2002
    Date of Patent: July 27, 2004
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Jong Ho Lee, Hyung Cheol Shin