Patents Assigned to Sciences
  • Publication number: 20040133863
    Abstract: The design methods and apparatuses of photodiodes with adaptive structures to achieve smooth and wavelength-selective responses are proposed. By using the adequate sizes of the photo-sensing areas and gains of the back-end amplifiers towards the different photo-responses of multiple photodiodes, the photo-responses from these photodiodes are summed together to yield the uniform distribution of the total photo-responses. Based on the physical characteristics of the process parameters, the equation of the photo-responses for the PN junction is derived to find the optimized values of the process parameters for increasing the photo-response and achieving the peak value of the photo-responses at a specific wavelength. The photodiode with multiple PN junctions and multiple switches is designed to achieve multiple photo-responses in a single photodiode. By using the switches to turn off the unused PN junctions, the selected PN junctions can generate the required photo-responses.
    Type: Application
    Filed: September 27, 2003
    Publication date: July 8, 2004
    Applicant: Chung-Shan Institute of Science and Technology
    Inventors: Li-Kuo Dai, Ping-Kuo Weng, Far-Wen Jih, Kaung-Hsin Huang, Wei-Jean Liu, Oscal Tzyh-Chiang Chen
  • Publication number: 20040129984
    Abstract: A SnO2 ISFET device and manufacturing method thereof. The present invention prepares SnO2 as the detection membrane of an ISFET by sol-gel technology to obtain a SnO2 ISFET. The present invention also measures the current-voltage curve for different pH and temperatures by a current measuring system. The temperature parameter of the SnO2 ISFET is calculated according to the relationship between the current-voltage curve and temperature. In addition, the drift rate of the SnO2 ISFET for different pH and hysteresis width of the SnO2 ISFET for different pH loop are calculated by a constant voltage/current circuit and a voltage-time recorder to measure the gate voltage of the SnO2 ISFET.
    Type: Application
    Filed: December 18, 2003
    Publication date: July 8, 2004
    Applicant: National Yunlin University of Science and Technology
    Inventors: Jung-Chuan Chou, Yii Fang Wang
  • Publication number: 20040130215
    Abstract: A submarine power feeding branching device comprises a constant current-constant current converter which isolates an input side for a trunk submarine cable from an output side for a branch submarine cable. The converter receives a first constant current and produces a second constant current by using the first constant current. The second constant current is supplied to the output side while the first constant current is returned to the input side. Because the input side and the output side are isolated, it is easy to add/remove the device to/from a submarine power feeding system. Intensity of the second constant current can be controlled by controlling duty ratios of switches included in the converter. Thus, it is possible that the intensity of the second constant current is equal to that of the first constant current. Therefore, a submarine repeater can be provided along either the trunk cable or the branch cable.
    Type: Application
    Filed: October 20, 2003
    Publication date: July 8, 2004
    Applicant: NEC CORPORATION and JAPAN MARINE SCIENCE AND TECHNOLOGY CENTER
    Inventors: Jun Muramatsu, Kenichi Asakawa, Katsuyoshi Kawaguchi
  • Publication number: 20040132671
    Abstract: This invention relates to quercetin derivative, its preparation, and a pharmaceutical combination, as well as their medical uses for the prevention or treatment of diseases related to 5HT1A receptor or neuron cell damages, including Alzeheimer's disease, drug or alcohol dependence, sleep disorders or panic state; and for delaying senility, improving learning and memory, preventing and treatment of neuron cell damages caused by various kinds of cerebral damages.
    Type: Application
    Filed: September 26, 2003
    Publication date: July 8, 2004
    Applicant: ACADEMY OF MILITARY MEDICAL SCIENCES INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY
    Inventors: Yimin Zhao, Ming Yang, Yunfeng Li, Xinhui Luan, Zhipu Luo
  • Publication number: 20040132991
    Abstract: Disclosed are taxanes having utility as intermediates in the preparation of paclitaxel, taxotere and analogs thereof, and methods related to the preparation of the same.
    Type: Application
    Filed: October 9, 2003
    Publication date: July 8, 2004
    Applicant: Phytogen Life Sciences Inc.
    Inventor: Ragina Naidu
  • Publication number: 20040131597
    Abstract: The present invention relates to novel antiproliferative genes. More specifically, isolated nucleic acid molecules are provided encoding the human B-cell translocation genes 2 and 3 (BTG-2 and BTG-3). BTG-2 and BTG-3 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same.
    Type: Application
    Filed: December 19, 2003
    Publication date: July 8, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Charles A. Kunsch, Arvind Chopra, Craig A. Rosen
  • Publication number: 20040132987
    Abstract: The present invention relates to a novel connective tissue growth factor-3 protein which is a member of the growth factor superfamily. In particular, isolated nucleic acid molecules are provided encoding the human connective tissue growth factor-3 protein. Connective tissue growth factor-3 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. Also provided are diagnostic and therapeutic methods for detecting and treating connective tissue related disorders.
    Type: Application
    Filed: November 26, 2003
    Publication date: July 8, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Reinhard Ebner, Arvind Chopra, Steven M. Ruben
  • Publication number: 20040133782
    Abstract: Systems and methods for executing electronic transactions on an anonymous basis using blind auditable membership proofs. By making use of a new cryptographic primitive, electronic transactions such as payment, voting, investment, redemption of tax coupon, and international currency transfer may be made both anonymous and auditable. In an electronic payment system according to the present invention, a user submits information identifying a coin to a bank which in turn validates the coin and adds it to a public list of valid coins. To make a payment using the coin, the user presents an efficient auditable membership proof to a merchant in the form of a zero knowledge argument which proves that the user knows the authenticating information for an unspecified coin in the public list of valid coins. The merchant verifies the zero knowledge argument, accepts the coin as payment, and presents certain authenticating information to the bank.
    Type: Application
    Filed: August 15, 2003
    Publication date: July 8, 2004
    Applicant: International Computer Science Institute, a California corporation
    Inventors: Tomas Sander, Amon Ta-Shma
  • Publication number: 20040129556
    Abstract: A magnetron sputtering electrode for use with a magnetron sputtering device, wherein the magnetron sputtering electrode comprises a cathode body, a drive unit coupled to the cathode body, a target received by the cathode body, and a closed loop magnet arrangement received within a magnet receiving chamber and coupled to the drive unit. The closed loop magnet arrangement is comprised of a plurality of magnets adapted for motion relative to the target by the drive unit, wherein at least one of the plurality of magnets is a profiled magnet having a contoured top portion. A method of improving target utilization in sputtering applications is also disclosed.
    Type: Application
    Filed: July 22, 2003
    Publication date: July 8, 2004
    Applicant: Angstrom Sciences, Inc.
    Inventor: Mark A. Bernick
  • Publication number: 20040131629
    Abstract: Betulin and dihydrobetulin acyl derivatives according to the present invention have been found to have potent anti-HIV activity. The compounds of the present invention have Formula I as described herein, or pharmaceutically acceptable salts thereof, wherein R1 is a C2-C20 substituted or unsubstituted carboxyacyl, R2 is hydrogen, chloro, bromo, or hydroxy, R4 is hydrogen or C(C6H5)3; wherein the dashed line represents an optional double bond between C20 and C29.
    Type: Application
    Filed: September 26, 2003
    Publication date: July 8, 2004
    Applicants: Panacos Pharmaceuticals, Inc., The University of North Carolina at Chapel Hill, Niigata University of Pharmacy and Applied Science
    Inventors: Graham P. Allaway, Carl T. Wild, Yoshiki Kashiwada, Kuo-Hsiung Lee
  • Publication number: 20040133574
    Abstract: A system and method for exchanging secure information is described. Sensitive documents are reduced to term vectors and document vectors. These vectors are mapped in to a latent semantic indexing space. Queries may be performed on the LSI space to determine if terms and documents are related.
    Type: Application
    Filed: January 7, 2003
    Publication date: July 8, 2004
    Applicant: Science Applications International Corporaton
    Inventor: Roger Bradford
  • Publication number: 20040132976
    Abstract: Human colon specific gene polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polynucleotides or polypeptides as a diagnostic marker for colon cancer and as an agent to determine if colon cancer has metastasized. Also disclosed are antibodies specific to the colon specific gene polypeptides which may be used to target cancer cells and be used as part of a colon cancer vaccine. Methods of screening for agonists and antagonists for the polypeptide and therapeutic uses of the antagonists are disclosed.
    Type: Application
    Filed: February 12, 2004
    Publication date: July 8, 2004
    Applicant: Human Genome Sciences, Inc.
    Inventors: Guo-Liang Yu, Craig A. Rosen
  • Publication number: 20040132666
    Abstract: The present invention provides methods for preventing or reducing ischemia-reperfusion injuries. These methods comprise administering an effective amount of a free radical scavenger (e.g., N-acetylcysteine) to a subject in need thereof.
    Type: Application
    Filed: September 22, 2003
    Publication date: July 8, 2004
    Applicant: Oregon Health & Science University
    Inventors: Edward A. Neuwelt, Leslie Muldoon
  • Publication number: 20040132763
    Abstract: Disclosed is a salt of amonafide or amonafide analogs represented Structural Formula (I): 1
    Type: Application
    Filed: October 20, 2003
    Publication date: July 8, 2004
    Applicant: Xanthus Life Sciences, Inc.
    Inventors: Alfred M. Ajami, David O. Barlow
  • Patent number: 6759025
    Abstract: A method of synthesizing carbon nanotubes and a carbon nanotube synthesizing apparatus used for the same are provided. A catalyst is introduced into the reactor, and the catalyst in the reactor is selectively and locally heated by a heating method such as microwave irradiation, electromagnetic inductive heating, radio frequency heating or laser heating. Here, carbon source gas, carbon source gas and hydrogen sulfide gas, or carbon source gas and hydrogen gas or inert gas is supplied into the reactor, thereby growing carbon nanotubes from the locally heated catalyst.
    Type: Grant
    Filed: April 27, 2001
    Date of Patent: July 6, 2004
    Assignees: Iljin Nanotech Co., Ltd., Pohang University of Science and Technology Foundation
    Inventors: Eun-Hwa Hong, Kun-Hong Lee, Chang-Mo Ryu, Jong-Hoon Han, Jae-Eun Yoo
  • Patent number: 6759513
    Abstract: The present invention relates to novel Death Domain Containing Receptor (DR3 and DR3-V1) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR3 and DR3-V1 proteins. DR3 and DR3-V1 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR3 and DR3-V1 activity.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: July 6, 2004
    Assignee: Human Genome Sciences, Inc.
    Inventors: Guo-Liang Yu, Jian Ni, Reiner L. Gentz, Patrick J. Dillon
  • Patent number: 6759512
    Abstract: A human F-spondin-like protein and DNA (RNA) encoding such protein and a procedure for producing such protein by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for treating spinal cord injuries and damage to peripheral nerves by promoting neural-cell adhesion and neurite extension, inhibiting tumor metastases and tumor angiogenesis, and stimulating wound repair. Antagonists are also disclosed which may be utilized to prevent malaria. Diagnostic assays for identifying mutations in nucleic acid sequence encoding a polypeptide of the present invention and for detecting altered levels of the polypeptide of the present invention for detecting diseases, for example, cancer, are also disclosed.
    Type: Grant
    Filed: October 13, 1998
    Date of Patent: July 6, 2004
    Assignee: Human Genome Sciences, Inc.
    Inventors: Gregg Hastings, Patrick J. Dillon
  • Patent number: 6759058
    Abstract: This invention relates to enteric-coated proliposomal formulations for oral medicaments. In particular, it relates to an enteric-coated proliposomal oral drug delivery system for poorly water soluble drugs and methods for making the same. The drug delivery system comprises a pharmaceutical agent, a phospholipid and an enteric coating material. The present invention provides enhanced stability and bioavailability for orally administered drugs.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: July 6, 2004
    Assignee: Western Center for Drug Development College of Pharmacy Western University of Health Sciences
    Inventor: Guru V. Betageri
  • Patent number: 6759461
    Abstract: A novel antioxidant has the advantages of both the hindered phenols and the phosphite antioxidant is prepared from phosphorus trichloride and 2,5-di-tert-butylhydroquinone, such as tetrakis-(2,5-di-tert-butyl-4-hydroxyphenyl)-2,5-di-tert-butyl-hydroquinonediyl diphosphite.
    Type: Grant
    Filed: July 17, 2002
    Date of Patent: July 6, 2004
    Assignee: Chung-Shan Institute of Science & Technology
    Inventors: Tseng-Rong Wu, Pin-Yang Yu, Yi-Chin Lin, Te-Chuan Chang
  • Patent number: 6759403
    Abstract: The present invention covers radiosensitizers containing as an active ingredient halogenated derivatives of boronated porphyrins containing multiple carborane cages having the structure which selectively accumulate in neoplastic tissue within the irradiation volume and thus can be used in cancer therapies including, but not limited to, boron neutron—capture therapy and photodynamic therapy. The present invention also covers methods for using these radiosensitizers in tumor imaging and cancer treatment.
    Type: Grant
    Filed: April 5, 2002
    Date of Patent: July 6, 2004
    Assignee: Brookhaven Science Associates, LLC
    Inventors: Michiko Miura, Daniel N. Slatkin