Patents Assigned to Sciences
  • Patent number: 9255106
    Abstract: Provided is a piperazinotriazole compound represented by general formula I or a pharmaceutically acceptable salt, stereoisomer, tautomer or hydrate thereof. Also provided are a pharmaceutical composition comprising the compound, a method for preparing the compound and a method of use thereof as a high-selectivity poly(adenosine diphosphate-ribose)polymerase-1 (PARP-1) inhibitor in the preparation of drugs for the prevention and/or treatment of PARP-related diseases.
    Type: Grant
    Filed: July 24, 2013
    Date of Patent: February 9, 2016
    Assignee: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
    Inventors: Ao Zhang, Zehong Miao, Na Ye, Xiajuan Huan, Zilan Song, Chuanhuizi Chen, Yi Chen, Jian Ding
  • Patent number: 9254300
    Abstract: Dermal fibroblasts permanently loose their ability to synthesize elastin, the major component of elastic fibers, shortly after puberty. This progressive loss of elastic fibers cannot be replaced, resulting in the physical signs of aging. The present invention provides methods and compositions containing the polyphenols ellagic acid and/or tannic acid for protection against degradation of cutaneous elastic fibers by the elastolytic enzymes. The use of ellagic acid and/or tannic acid increased the overall deposition of elastic fibers in healthy and damaged skin cells. The protection of both intra-tropoelastin and extra-cellular mature elastic fibers from proteolytic enzymes by ellagic acid and tannic acid caused an increase in the net deposition of elastic fibers. Therefore, embodiments of the present invention provide methods and composition for the treatment of skin and prevention and treatment of degradation of dermal elastic fibers.
    Type: Grant
    Filed: January 8, 2014
    Date of Patent: February 9, 2016
    Assignees: Human Matrix Sciences, LLC, The Hospital for Sick Children
    Inventors: Thomas Mitts, Felipe Jimenez, Aleksander Hinek
  • Patent number: 9257208
    Abstract: A system for producing a controllable beam of radiation is controllable electronically, and includes no parts that must move relative to one another while in operation to form the beam. The direction and cross-section of the beam may be controlled electronically by controlling an electron beam. Various embodiments provide an X-ray collimator that allows forming a scanning X-ray beam of desired size and flux independently of the aperture material thickness without requiring movement of the aperture or physical components that create the aperture. Some embodiments provide an X-ray collimator that allows forming a scanning X-ray beam of desired size and flux independently of the beam angle.
    Type: Grant
    Filed: June 26, 2015
    Date of Patent: February 9, 2016
    Assignee: American Science and Engineering, Inc.
    Inventor: Martin Rommel
  • Patent number: 9255224
    Abstract: Provided is a method of amplification of coke oven gas (COG) through reacting high-temperature carbon with carbon dioxide and/or water using waste heat generated in a coke oven. More particularly, a method of amplification of COG including providing a gasification agent including carbon dioxide, water, or a mixture thereof to a COG stream in a carburization chamber of a coke oven and gasifying carbon by allowing the gasification agent to react with carbon in the carburization chamber, and a coke oven apparatus suitable for the method are provided.
    Type: Grant
    Filed: December 29, 2010
    Date of Patent: February 9, 2016
    Assignee: Research Institute of Industrial Science & Technology
    Inventors: Joo-Hyoung Park, Hee-Dong Chun, Je-Young Kim, Heung-Soo Park, Min-Young Yi, Kun-Woo Han, Chang-Houn Rhee, Sung-Uk Ryu
  • Patent number: 9255274
    Abstract: An object of the present invention is to provide a translationally regulatable mRNA which has wider application and can perform specific ON-OFF regulation, an RNA-protein complex specifically bound to the mRNA, and a translational regulatory system. The present invention provides an mRNA having an RNA-protein complex interacting motif-derived nucleotide sequence 5? to the ribosome-binding site or within the 5? region of the open reading frame, and an mRNA having a nucleotide sequence complementary to an RNA-protein complex interacting motif-derived nucleotide sequence 5? to the ribosome-binding site or within the 5? region of the open reading frame.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: February 9, 2016
    Assignee: Japan Science and Technology Agency
    Inventors: Tan Inoue, Hirohide Saito, Tetsuhiro Kobayashi, Tomoaki Hara
  • Patent number: 9255039
    Abstract: Improved agriculturally useful products are provided, including solid materials such as nitrogenous fertilizers (e.g., urea), together with a polycarboxylated polymer selected from the group consisting of a salts of copolymers containing individual quantities of maleic and itaconic moieties. The polymer composition also includes from about 10-60% by weight of an organic drying agent such as a lower alcohol which enhances the quick drying properties thereof. The compositions may also include an amount of boron, and bimodal vinylic polymer made up of quantities of high and low molecular weight (MW) vinylic polymers such as PVA.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: February 9, 2016
    Assignee: Verdesian Life Sciences, LLC
    Inventors: John Larry Sanders, Grigory Mazo, Jacob Mazo
  • Patent number: 9254305
    Abstract: The present invention relates to a use of Substance-P for the manufacture of a medicament for mobilization or proliferation of Mesenchymal stem cells (MSCs) from the bone marrow, or facilitating said mobilization or proliferation, and use of Substance-P for the manufacture of a medicament for wound-healing or facilitating wound-healing.
    Type: Grant
    Filed: September 5, 2013
    Date of Patent: February 9, 2016
    Assignees: Korea Institute of Radiological & Medical Sciences, Chung-Ang University Industry-Academy Cooperation Foundation
    Inventors: Young Sook Son, Hyun Sook Hong, Jae Chan Kim
  • Patent number: 9256066
    Abstract: Irradiance control systems (“ICSs”) that control the irradiance of a beam of light are disclosed. ICSs include in a beam translator and a beam launch. The beam translator translates the beam substantially perpendicular to the propagating direction of the beam with a desired displacement so that the beam launch can remove a portion of the translated beam and the beam can be output with a desired irradiance. The beam launch attenuates the irradiance of the beam based on the amount by which the beam is translated. ISCs can be incorporated into fluorescent microscopy instruments to provide high-speed, fine-tune control over the irradiance of excitation beams.
    Type: Grant
    Filed: January 16, 2012
    Date of Patent: February 9, 2016
    Assignee: GE Healthcare Bio-Sciences Corp.
    Inventors: Jeremy R. Cooper, Steven A. Reese, William M. Dougherty
  • Patent number: 9258285
    Abstract: A system may include and/or involve a first device, a second device, and logic to effect pairing of the first and second devices upon activation of contact sensors of both the first and second devices.
    Type: Grant
    Filed: May 24, 2005
    Date of Patent: February 9, 2016
    Assignee: Invention Science Fund I, LLC
    Inventors: John D. Rinaldo, Jr., Royce A. Levien, Robert W. Lord, Alexander J. Cohen, Mark A. Malamud, Edward K. Y. Jung
  • Patent number: 9254402
    Abstract: The present invention discloses a movement facilitative device, basically comprising a first fixing module, a second fixing module, an energy storing module and a switching module, wherein the first fixing module and the second fixing module are fixed on the first extremity and the second extremity of the animal respectively. The first fixing module is connected with the second fixing module. The present invention has the advantages of decreasing the force required by the muscles during the exercise as well as retarding the impact enforced thereon while the user is jogging or exercising. Furthermore, the switching module of the present invention minimizes the limitations to the movement of the user so as to let the user exercise more effortlessly.
    Type: Grant
    Filed: July 20, 2012
    Date of Patent: February 9, 2016
    Assignee: National Taiwan University of Science and Technology
    Inventors: Mau-Pin Hsu, Jheng-Ying Lin, Jia-Yang Liang
  • Patent number: 9256749
    Abstract: A method for invoking an application in a Screen Lock screen is disclosed herein. The method for invoking an application in a user equipment includes the steps of selecting at least one unlock application that is to be displayed on a Screen Lock screen among multiple applications, and displaying an unlock application icon respective to each of the select at least one unlock application on the Screen Lock screen.
    Type: Grant
    Filed: July 24, 2014
    Date of Patent: February 9, 2016
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Jun Kyun Choi, Hyo Jin Park, Jin Hong Yang
  • Patent number: 9256324
    Abstract: An interactive operation method of an electronic apparatus is provided. An image sequence is captured by an image capturing unit. An image pre-processing is executed on an image of the image sequence. A fingertip candidate region is obtained from the image. Whether the fingertip candidate region is connected with a hand region is determined. If the fingertip candidate region is connected with the hand region, the fingertip candidate region serves as a target fingertip region. Whether a click event occurs is determined by continuously tracking the target fingertip region. When the click event occurs, a corresponding function is executed.
    Type: Grant
    Filed: December 19, 2013
    Date of Patent: February 9, 2016
    Assignee: National Taiwan University of Science and Technology
    Inventors: Bai-Ruei Huang, Chang-Hong Lin, Chia-Han Lee
  • Publication number: 20160034596
    Abstract: Disclosed is a method and system for browsing a virtual object. A virtual object browsing method includes acquiring identification information of a captured object from the object, acquiring information about a service provider of a virtual object mapped to the identification information, and acquiring related information of the object from the corresponding service provider based on the information about the service provider.
    Type: Application
    Filed: February 12, 2015
    Publication date: February 4, 2016
    Applicant: Korea Advanced Institute of Science and Technology
    Inventors: Jun Kyun Choi, Jin Hong Yang, Hyo Jin Park
  • Publication number: 20160032328
    Abstract: The invention relates to the use of EntD polypeptides, polynucleotides encoding the same, and homologues thereof to enhance the production of fatty aldehydes and fatty alcohols in a host cell.
    Type: Application
    Filed: February 13, 2014
    Publication date: February 4, 2016
    Applicant: REG Life Sciences, LLC
    Inventors: Zhihao HU, Derek L. GREENFIELD, Vikranth ARLAGADDA
  • Publication number: 20160032475
    Abstract: A cluster of non-collapsed nanowires, a template to produce the same, methods to obtain the template and to obtain the cluster by using the template, and devices comprising the cluster are described. The cluster and the template both have an interconnected region and an interconnection-free region.
    Type: Application
    Filed: July 30, 2015
    Publication date: February 4, 2016
    Applicants: IMEC VZW, King Abdulaziz City for Science and Technology
    Inventors: Cedric Huyghebaert, Alaa Abd-Elnaiem, Philippe Vereecken
  • Publication number: 20160031921
    Abstract: An oxygen assisted Organosolv process for a more efficient delignification and producing bio-products by decomposing lignocellulosic materials comprises providing a lignin solvent with water, an acid, an oxidant and one or more lignin dissolving chemicals. The process also includes placing biomass in contact with oxidant, acid, water, the lignin solvent in any order or combined to form a recyclable solvent, and recycling at least a portion of the recyclable solvent by circulating the recyclable solvent back into contact with the biomass. The circulating of the recyclable solvent occurs for a period of time, during which, acid and oxidant may be added if necessary as they may be consumed by the process, after which, the process then includes separating material such as chemicals and lignin from the recyclable solvent.
    Type: Application
    Filed: August 1, 2014
    Publication date: February 4, 2016
    Applicant: American Science and Technology Corporation
    Inventors: Ali Manesh, John H. Guenther, Edwin G. Zoborowski, Walter Braenner, Mohammad Ali Manesh, Lee J. Hawk
  • Patent number: 9249013
    Abstract: Compositions for directed self-assembly patterning techniques are provided which avoid the need for separate anti-reflective coatings and brush neutral layers in the process. Methods for directed self-assembly are also provided in which a self-assembling material, such as a directed self-assembly block copolymer, can be applied directly to the silicon hardmask neutral layer and then self-assembled to form the desired pattern. Directed self-assembly patterned structures are also disclosed herein.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: February 2, 2016
    Assignee: Brewer Science Inc.
    Inventors: Yubao Wang, Mary Ann Hockey, Douglas J. Guerrero, Vandana Krishnamurthy, Robert C. Cox
  • Patent number: 9250443
    Abstract: Disclosed are a head-mounted display apparatus and a contents display method. The head-mounted display apparatus includes: a mobile device tracing information processing unit for receiving position information or orientation information of a mobile device and generating tracing information of the mobile device based on the received position information or orientation information of the mobile device; a gesture processing unit for receiving input information of the mobile device and generating gesture information to change an output format of contents by using the received input information; a rendering unit for generating a predetermined virtually augmented contents image based on the tracing information of the mobile device and the gesture information; and a display unit for displaying the generated virtually augmented contents image.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: February 2, 2016
    Assignee: Korea Institute of Science and Technology
    Inventors: Ji Hyung Park, Dong Wook Yoon, Yong Hun Choi, Joong Ho Lee
  • Patent number: 9249360
    Abstract: Wax compositions derived from metathesized natural oils and amines and methods of making wax compositions from metathesized natural oils and amines are provided. The wax compositions comprise amidated metathesized natural oils formed from a metathesized natural oil and at least one amine. The methods comprise providing an amine and providing a metathesized natural oil. The methods further comprise mixing the amine and the metathesized natural oil in the presence of a basic catalyst or heat, causing a reaction between the amine and metathesized natural oil, therein forming the amidated metathesized natural oil.
    Type: Grant
    Filed: July 6, 2011
    Date of Patent: February 2, 2016
    Assignee: Elevance Renewable Sciences, Inc.
    Inventors: Monika Mujkic, Deidra Cade, Choon Woo Lee, Michael S. Starch, Brian J. Swanton
  • Patent number: 9252020
    Abstract: Proposed are a composite material having a high adhesiveness, wherein non-penetrating pores that are formed in a silicone surface layer are filled up with a metal or the like without leaving any voids by using the plating technique and the silicone surface layer is coated with the metal or the like, and a method of producing the composite material. A composite material, which has a high adhesiveness between a second metal or an alloy of the second metal (106a, 106b) and a silicone surface, can be obtained by filling up non-penetrating pores that are formed in the surface of a silicone substrate (100) substantially with a second metal or an alloy of the second metal (106a) with the use of the autocatalytic electroless plating technique wherein a first metal located at the bottom of the non-penetrating pores as described above serves as the starting point, and coating the surface of the silicone substrate (100) with the second metal (106b).
    Type: Grant
    Filed: May 1, 2013
    Date of Patent: February 2, 2016
    Assignee: Japan Science and Technology Agency
    Inventors: Shinji Yae, Tatsuya Hirano, Hitoshi Matsuda