Abstract: A medical device including an electric measurement circuit, in which are connected at least two sensors the impedance of which varies as a function of a sensed physical parameter, a source of electrical power for powering the electric measurement circuit, an antenna for emitting an electromagnetic field as a function of the impedance of the electric measurement circuit, each of the sensors being associated with a switch for short circuiting the sensor in the measurement circuit, the medical device further including a system for controlling the switches in order successively to command the opening or closing of the switches in determined configurations. The medical device may notably be able to be applied to the human body or implanted in the human body.
Type:
Application
Filed:
October 2, 2015
Publication date:
August 23, 2018
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE POLYTECHNIQUE, ECOLE NORMALE SUPERIEURE DE CACHAN
Inventors:
Abdul BARAKAT, Franz BOZSAK, Yvan Eric BONNASSIEUX, Bruno LE PIOUFLE, Olivier FRANCAIS, Bruno CARREEL
Abstract: In an example of a method for simultaneously fixing and staining cells, the cells are initially incubated in a solution including a Ln(III)Zn16(HA ligand)16 metallacrown complex, wherein the HA ligand is a hydroximate ligand. The incubating cells are exposed to ultraviolet (UV) light. The cells are allowed to continue to incubate in the solution after UV light exposure.
Type:
Application
Filed:
August 12, 2016
Publication date:
August 23, 2018
Applicants:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Ivana MARTINIC, Tu Ngoc NGUYEN, Svetlana V. ELISEEVA, Vincent L. PECORARO, Stéphane PETOUD
Abstract: A method for manufacturing a resistive device, includes depositing a first electrically conductive layer on a substrate; forming an etching mask on the first conductive layer; etching the first conductive layer through the mask, such as to obtain a plurality of electrically conductive pillars separated from one another; and forming storage elements with variable electrical resistance at the tops of the electrically conductive pillars, such that each storage element is supported by one of the electrically conductive pillars, the step of forming the storage elements including the following operations depositing a first layer by non-collimated cathode sputtering at normal incidence relative to the substrate; and depositing a second layer on the first layer by cathode sputtering, the second layer including a first chemical species sputtered at an oblique incidence.
Type:
Grant
Filed:
October 15, 2015
Date of Patent:
August 21, 2018
Assignees:
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE GRENOBLE ALPES
Inventors:
Bernard Dieny, Maxime Darnon, Gabriele Navarro, Olivier Joubert
Abstract: The present invention concerns the use of a compound having the following formula (I), for the preparation of a polymer. The present invention also concerns the polymers obtained from polymerization of compound of formula (I), and their processes of preparation.
Type:
Grant
Filed:
October 10, 2015
Date of Patent:
August 21, 2018
Assignees:
UNIVERSITÉ DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)
Abstract: Selective inhibitor of c-Fos and their antiproliferative properties The invention relates to selective inhibitor of c-Fos for use in the prevention and/or treatment of cancers and restenosis.
Type:
Grant
Filed:
April 8, 2015
Date of Patent:
August 21, 2018
Assignees:
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
Abstract: The present invention relates to a process for preparing epitaxial ?-quartz layers on a solid substrate, to the material obtained according to this process, and to the various uses thereof, especially in the electronics field.
Type:
Grant
Filed:
July 22, 2013
Date of Patent:
August 21, 2018
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC)
Abstract: A method for fabricating a ferroelectric tunnel junction, comprising growing a hafnium zirconium oxide film barrier layer by sputtering in the presence of oxygen at a temperature of at most 425° C., on a conductive material as a bottom electrode, and depositing a conductive material as a top electrode.
Type:
Grant
Filed:
June 22, 2017
Date of Patent:
August 21, 2018
Assignees:
INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE, PLASMIONIQUE INC.
Abstract: The invention relates to an assistive device for positioning a medical instrument (2) inserted into a natural duct (100) or an artificial duct of a patient relative to an internal organ (P) of a patient, wherein the device comprises a support (1) that is to be inserted at least in part into the body of the patient and supports the medical instrument, means for moving the support, wherein said movement means comprise an articulated arm (9) that includes a plurality of degrees of freedom for moving a proximal end (1a) of the support, means for acquiring images of the internal organ for positioning the medical instrument relative to the internal organ, wherein the image acquisition means comprise a probe (5) supported by the support such that the medical instrument and the probe are rigidly connected, and a control unit (10) for controlling the movement means, which is connected to the image acquisition means and comprises image analyzing means (11) for generating control commands for the articulated arm in orde
Type:
Grant
Filed:
December 6, 2012
Date of Patent:
August 21, 2018
Assignees:
SORBONNE UNIVERSITE, KOELIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Cecile Poquet, Pierre Mozer, Michael Baumann, Marie-Aude Vitrani, Guillaume Morel, Antoine Leroy, Patrick Henry, Gregoire Coffin
Abstract: A process for the specific isotopic labeling of an amino acid selected from Valine (Val), Leucine (Leu), and Isoleucine (Ile), in proteins and biomolecular assemblies by introducing, in a medium containing bacteria overexpressing a protein, an acetolactate derivative of Formula I of the application.
Type:
Grant
Filed:
June 13, 2017
Date of Patent:
August 21, 2018
Assignees:
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JOSEPH FOURIER
Inventors:
Pierre Gans, Jerome Boisbouvier, Isabel Ayala, Olivier Hamelin
Abstract: The invention relates to an active ingredient which is a live attenuated recombinant measles virus expressing influenza A virus antigen(s) and to its use in the elicitation of immunity, in particular protective immunity and advantageously broad-spectrum protective immunity against influenza A virus. In particular, the influenza A virus is selected among epidemic seasonal viruses and/or endemic viruses circulating in the human population and advantageously encompasses a pandemic virus such as H1N1v.
Type:
Application
Filed:
June 10, 2016
Publication date:
August 16, 2018
Applicants:
INSTITUT PASTEUR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Nicolas Robert Xavier ESCRIOU, Frederic TANGY, Ho Hong Hai VO
Abstract: The present invention concerns a compound of formula (I): wherein: —n is an integer comprised between 1 and 7; —X1 is in particular a radical of formula —CH2—S—(CH2)k—S—; —A1 is in particular a linear or branched alkylene radical comprising from 2 to 30 carbon atoms, and —X2 is in particular an alkoxy group of formula ORa, wherein Ra is a linear or branched alkyl group comprising from 1 to 10 carbon atoms.
Type:
Grant
Filed:
December 16, 2015
Date of Patent:
August 14, 2018
Assignees:
UNIVERSITÉ DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT DES CORPS GRAS ETUDES ET RECHERCHES TECHNIQUES-ITERG, INSTITUT POLYTECHNIQUE DE BORDEAUX, INSTITUT TECHNOLOGIQUE FCBA
Inventors:
Henri Cramail, Stéphane Jean-Pierre Albert Grelier, Frédérique Pichavant, Denilson Da Silva Perez, Carine Alfos, Maud Suzanne Chemin
Abstract: The present invention relates to luminescent lanthanide complexes including a chelating agent, formed with a macrocycle or a set of ligands, complexing a lanthanide ion Ln3+, wherein the chelating agent is substituted with at least two groups. The invention is most particularly applied to lanthanide complexes, the chelating agent of which is formed the with three ligands integrating a 2,6 pyridine-di(carboxylic acid) or is formed with a macrocycle having a 1,4,7 triazacyclononane structure.
Type:
Grant
Filed:
April 3, 2014
Date of Patent:
August 14, 2018
Assignees:
ECOLE NORMALE SUPERIEURE DE LYON, UNIVERSITE CLAUDE BERNARD LYON I, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Abstract: The invention relates to a process for preparing nanoparticles of a catalyst for cathodic reduction and which is tolerant to methanol, these nanoparticles comprising a metallic center and a submonolayer of a chalcogen.
Type:
Grant
Filed:
June 20, 2013
Date of Patent:
August 14, 2018
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE DE POITIERS
Inventors:
Nicolas Alonso-Vante, Jiwei Ma, Aldo Gago
Abstract: The present invention relates to a compound of formula (I): wherein A and A? independently represent a phenylene group or a pyridylene group; R2 is a hydrogen atom or a (C1-C4)alkyl group; R3 is a 2-pyridyl group, 3-pyridyl group, a 4-pyridyl group, a 2-pyrimidinyl group, a 4-pyrimidinyl group or a 5-pyrimidinyl group; R4 is a carbonyl group or a sulfonyl group; and R5 is a —NH—(CH2)a—NR6R7 group or a 4-methylpiperazinyl group, with a being an integer from 1 to 4, R6 and R7 representing independently a (C1-C4)alkyl group, or R6 and R7 together with the nitrogen atom to which they are linked forming a heterocycle group which is chosen among a 4-methylpiperazinyl group, a morpholino group, a pyrrolidinyl group and a piperidino group; or any one of its pharmaceutically acceptable salt.
Type:
Application
Filed:
April 5, 2018
Publication date:
August 9, 2018
Applicants:
ABIVAX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT CURIE, UNIVERSITE DE MONTPELLIER
Abstract: A method for determining a location of a reflecting scatterer (S) in a medium (M) including a transmitting step in which a transducer (4) emits a transmit wave (T), a receiving step in which a receive array (3) provide transducer signals in response to a reflected wave (R), a beam forming step in which beam formed signals are computed, an interferometric processing step during which a complex interferometric signal is determined as a function of products of beam formed signals and conjugate of beam formed signals and a location determining step in which interferometric beam samples are selected from the complex interferometric signal, based on their complex arguments. The selected interferometric beam samples are indicatives of the location of the reflecting scatterer (S).
Type:
Grant
Filed:
August 1, 2014
Date of Patent:
August 7, 2018
Assignees:
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS
Abstract: The invention relates to an ion thruster, comprising: a chamber, a reservoir, comprising a solid propellant (PS), housed in the chamber and comprising a conductive jacket provided with an orifice; means for forming an ion-electron plasma in the chamber, which means are able to sublime the solid propellant in the reservoir, then to generate said plasma in the chamber from the sublimed propellant coming from the reservoir through the orifice; a means for extracting and accelerating the ions and electrons of the plasma out of the chamber, which means comprises at least two grids at one end (E) of the chamber; a radiofrequency AC voltage source for generating a radiofrequency signal comprised between the plasma frequencies of the ions and of the electrons, arranged in series with a capacitor and connected, by one of its outputs and via this capacitor, to one of the grids, with the other grid being connected to the other output of said voltage source; said means for extracting and accelerating and said voltage
Type:
Application
Filed:
August 30, 2016
Publication date:
August 2, 2018
Applicants:
ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Abstract: The invention relates to an acoustic-optical imaging method and system of a zone for observing an environment. The system includes an acquisition device comprising, a network of transducers for generating a plurality of non-focussed sound waves, a light-emitting device for emitting an incident light wave and generating marked light waves comprising an acoustic-optical component that is shifted in frequency by the non-focussed sound waves, and a detector for acquiring measurement signals. The system also comprises a processing device for determining a light intensity in the observation zone from the measurement signals.
Type:
Application
Filed:
June 2, 2015
Publication date:
August 2, 2018
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE- INSERM
Inventors:
François Ramaz, Mickaël Tanter, Jean-Baptiste Laudereau, Jean-Luc Gennisson
Abstract: The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative, cyclolipopeptides which may be obtained from this bacterium, a composition comprising at least such a cyclolipopeptide, as well as to their uses.
Type:
Application
Filed:
March 27, 2018
Publication date:
August 2, 2018
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE DE RENNES 1, UNIVERSITE DE BRETAGNE OCCIDENTALE
Inventors:
Florie DESRIAC, Yannick FLEURY, Patrick LE CHEVALIER, Delphine DESTOUMIEUX, Matthieu SIMON
Abstract: A power switching cell with normally on field-effect transistors comprises a current switch receiving the control input signal over an activation input and a power transistor for switching a high voltage VDD applied to its drain, to its source that is connected to the output port of the cell. The control of the gate of the power transistor whose source is floating, according to the input signal, is provided by a self-biasing circuit connected between its gate and source. The current switch is connected between the self-biasing circuit and a zero or negative reference voltage. The self-biasing circuit comprises a transistor whose source or drain is connected to the gate or source of the power transistor. The gate of this transistor is biased by a resistor connected between its gate and source, and between the current switch and the source. The transistors are HEMT transistors using GaN or AsGa technology.
Type:
Grant
Filed:
April 17, 2015
Date of Patent:
July 31, 2018
Assignees:
THALES, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE DE LIMOGES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Olivier Jardel, Raymond Quere, Stéphane Piotrowicz, Philippe Bouysse, Sylvain Delage, Audrey Martin
Abstract: The present invention relates to novel 3,5-bis(fluoroalkyl)pyrazole-4-carboxylic acid derivatives and to a process for preparing 3,5-bis(fluoroalkyl)pyrazole-4-carboxylic acid derivatives and 3,5-bis(fluoroalkyl)pyrazoles.
Type:
Grant
Filed:
March 3, 2016
Date of Patent:
July 31, 2018
Assignees:
BAYER CROPSCIENCE AG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Sergii Pazenok, Norbert Lui, Jean-Pierre Vors, Frederic R Leroux, Florence Giornal