Patents Assigned to SCIENTIFIQUE (CNRS)
  • Patent number: 10120334
    Abstract: A system for recording a digital hologram of an object comprises: a coherent source intended to illuminate the object and thus produce a wave diffracted by the object; and a digital sensor intended to record the digital hologram of the object. It furthermore comprises a spatial phase modulating assembly able to produce in the plane of the sensor a plurality of duplicates of the wave diffracted by the object, the duplicates being offset from each other but overlapping partially, these duplicates forming on the sensor a digital hologram of the object, this hologram being what is referred to as a self-reference hologram.
    Type: Grant
    Filed: October 28, 2013
    Date of Patent: November 6, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DU MAINE, INSTITUT DES MOLECULES ET MATERIAUX DU MANS (IMMM-UMR 6283)
    Inventors: Pascal Picart, Mokrane Malek
  • Patent number: 10119204
    Abstract: Some embodiments are directed to a method and a device that allows fragile fibers, such as carbon fibers, for example, to be recycled so that they can be reused in a new form.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: November 6, 2018
    Assignees: UNIVERSITË DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Olivier Mantaux, Arnaud Gillet, Matthieu Pedros
  • Patent number: 10119856
    Abstract: A method is provided for detecting a perturbation with respect to an initial state, of a device including at least one resonant mechanical element exhibiting a physical parameter sensitive to a perturbation such that the said perturbation modifies the resonance frequency of the said resonant mechanical element. A device is provided for detecting a perturbation by hysteretic cycle having at least one electromechanical resonator with nonlinear behavior and means for actuation and detection of the reception signal via a transducer so as to analyze the response signal implementing the method. A mass sensor and a mass spectrometer using the device are also provided.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: November 6, 2018
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, ECOLE NATIONALE TRAVAUX PUBLICS DE L'ETAT, INSTITUT NATIONAL SCIENCES APPLIQUEES DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Sebastien Hentz, Sebastien Baguet, Regis Dufour, Claude-Henri Lamarque, Van Nghi Nguyen
  • Publication number: 20180312629
    Abstract: The present invention relates to a compound that may be obtained according to a method comprising at least one polymerization step of at least one monomer of formula (I) below: wherein the polymerization step is carried out in the presence of a catalyst selected from the group consisting of: Zn(OAc)2, Ti(OBu)4, Ti(OiPr)4, Sb2O3, stannous octanoate, dibutyltin oxide, 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene, NaOMe, 1,5,7-triazabicyclo[4.4.0]dec-5-ene and Lipase B Candida Antartica.
    Type: Application
    Filed: October 28, 2016
    Publication date: November 1, 2018
    Applicants: PIVERT, UNIVERSITÉ DE BORDEAUX, INSTITUT DES CORPS GRAS ETUDES ET RECHERCHES TECHN IQUES - ITERG, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Blandine TESTUD, Etienne GRAU, Daniel TATON, Henri CRAMAIL, Didier PINTORI
  • Publication number: 20180312813
    Abstract: The invention relates to a method for reprogramming cells from aged donors or senescent cells to pluripotent cells that have lost marks of senescence. In particular, the invention relates to an ex vivo method for preparing induced pluripotent stein cells (iPSCs) from a target cell population comprising cells from aged donors or senescent cells, said method comprising the steps of culturing said target cell population tinder appropriate conditions for reprogramming said cells into iPSCs, wherein said appropriate conditions comprises increasing expression in said target cells, of at least the following reprogramming factors: Oct4, Klf4, Sox2, Myc, Lin28 and, optionally Nanog.
    Type: Application
    Filed: July 6, 2018
    Publication date: November 1, 2018
    Applicants: INSERM (Institut National de la Santé et de la Recherche Médicale), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE MONTPELLIER I, UNIVERSITE MONTPELLIER II
    Inventors: Alexandre Prieur, Ollivier Milhavet, Jean-Marc Lemaitre, Laure Lapasset
  • Patent number: 10111961
    Abstract: Microparticles and nanoparticles of hydrophobized proteins and an alpha-cyclodextrin, obtained by auto-association in an aqueous medium, the hydrophobized protein being obtained by grafting of alkyl chains coming from fatty acids, by an acylation reaction. These microparticles and nanoparticles constitute systems used for encapsulation of active substances of interest, in particular in the pharmaceutical field, and the vectorization thereof for therapeutic purposes.
    Type: Grant
    Filed: May 2, 2014
    Date of Patent: October 30, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-SUD XI
    Inventor: Kawthar Bouchemal
  • Patent number: 10115013
    Abstract: Accurate localization of isolated particles is important in single particle based super-resolution microscopy. It allows the imaging of biological samples with nanometer-scale resolution using a simple fluorescence microscopy setup. Nevertheless, conventional techniques for localizing single particles can take minutes to hours of computation time because they require up to a million localizations to form an image. In contrast, the present particle localization techniques use wavelet-based image decomposition and image segmentation to achieve nanometer-scale resolution in two dimensions within seconds to minutes. This two-dimensional localization can be augmented with localization in a third dimension based on a fit to the imaging system's point-spread function (PSF), which may be asymmetric along the optical axis. For an astigmatic imaging system, the PSF is an ellipse whose eccentricity and orientation varies along the optical axis.
    Type: Grant
    Filed: July 17, 2015
    Date of Patent: October 30, 2018
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventor: Jean-Baptiste Sibarita
  • Patent number: 10116114
    Abstract: According to the invention, a plurality of elementary laser beams (fi) are generated, the phases of which are adjusted by an electro-optical feedback loop (6, 7i, 8i, 9) implementing the matrix equation of a phase-contrast filtering device (6).
    Type: Grant
    Filed: October 14, 2015
    Date of Patent: October 30, 2018
    Assignees: COMPAGNIE INDUSTRIELLE DES LASERS CILAS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE LIMOGES
    Inventors: Vincent Kermene, Agnes Desfarges-Berthelemot, Paul Armand, Joel Benoist, David Kabeya, Alain Barthelemy, David Sabourdy, Jean-Eucher Montagne
  • Patent number: 10106493
    Abstract: Compounds of formula wherein n is 0, 1 or 2; X is and Ar is a benzyl substituted at the meta position by a C1 to C8 alkoxy group, or a pharmaceutically acceptable salt thereof, for treating, preventing or inhibiting a parasitic disease, such as toxoplasmosis, in a subject are provided. Methods for preparing the compounds are also presented.
    Type: Grant
    Filed: July 17, 2014
    Date of Patent: October 23, 2018
    Assignees: INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (I.R.D.), UNIVERSITE DE MONTPELLIER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Denis Sereno, Gilles Labesse, Jean-Francois Alexandre Guichou, Corinne Loeuillet, Deborah Isabelle Garcia, Stephane Delbecq
  • Patent number: 10105380
    Abstract: A molecule responding to formula (I) of the glycocluster type with galactose residues at their extremities. Simple and efficient methods for the preparation of these compounds. Medical use of compounds (I) as inhibitors of infections by Pseudomonas aeruginosa, more specifically as inhibitors of Pseudomonas aeruginosa's virulence.
    Type: Grant
    Filed: September 22, 2014
    Date of Patent: October 23, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER 1
    Inventors: Francois Morvan, Jean-Jacques Vasseur, Caroline Ligeour, Yann Chevolot, Eliane Souteyrand, Olivier Vidal, Alice Goudot, Sebastien Vidal
  • Patent number: 10106722
    Abstract: A copolymer containing a unit including an optionally neutralized styrene sulphonic acid unit and a unit containing at least one optionally neutralized (poly)carboxylic acid unit or a (poly)amido-amine unit, to inhibit or slow the formation of sulphide deposits during the extraction of gas or oil. It also relates to a method to inhibit or slow the formation of sulphide deposits during the extraction of gas or oil, including the injection of a fluid containing the abovementioned copolymer into a wellbore, a subterranean formation or a gas or oil well.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: October 23, 2018
    Assignees: TOTAL SA, UNIVERSITE LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Christian Hurtevent, Salima Baraka-Lokmane, John-Richard Ordonez-Varela, Olivier Tillement, Fabien Rossetti, Mahmoud Ould Metidji
  • Patent number: 10109860
    Abstract: The present invention relates to the field of lithium-sulphur batteries having high energy and power densities. In particular the present invention relates to a lithium-sulphur battery comprising a porous separator made of biaxially oriented polypropylene and to its process of manufacture.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: October 23, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, BLUE SOLUTIONS, UNIVERSITE DE NANTES
    Inventors: Margaud Lecuyer, Marc Deschamps, Joël Gaubicher, Bernard Lestriez, Dominique Guyomard, Philippe Poizot
  • Patent number: 10106415
    Abstract: The present invention concerns a process for the production of boron phosphide BP comprising the reduction of boron phosphate BPO4 with at least one alkaline earth metal (EA) according to Equation (1): BPO4+4 EA?BP+4 EA(O)(1).
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: October 23, 2018
    Assignees: SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIV PARIS XIII PARIS-NORD VILLETANEUSE
    Inventors: Yann Le Godec, Vladimir Mukhanov, Vladimir Solozhenko, Petr Sokolov
  • Patent number: 10107781
    Abstract: A method for separating a plurality of deformable objects, such as biological cells or biological supramolecules such as DNA, in a liquid medium by use of an electrophoretic technique combined with hydrodynamic forces. The deformable objects are introduced into a channel, having a flow axis and a cross section at right angles to the flow axis, with the minimum size of the cross section being less than or equal to 50 pm; A hydrodynamic flow is defined a in the channel together with the application of an electric field in the channel, making it possible to move the deformable objects in the channel according to the flow axis and to separate them along the flow axis. A device suitable for implementing this method. The electrolyte used for the electrophoretic separation may be a non-Newtonian fluid with viscoelastic properties.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: October 23, 2018
    Assignee: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Aurélien Bancaud, Hubert Ranchon
  • Patent number: 10109057
    Abstract: Asynchronous information is provided by a sensor having a matrix of pixels disposed opposite the scene. The asynchronous information includes, for each pixel of the matrix, successive events originating from this pixel, that may depend on variations of light in the scene. A model representing the tracked shape of an object is updated after detecting events attributed to this object in the asynchronous information. Following detection, the updating of the model includes an association of a point of the model with the event detected by minimizing a criterion of distance with respect to the pixel of the matrix from which the detected event originates. The updated model is then determined as a function of the pixel of the matrix from which the detected event originates and attributed to the object and of the associated point in the model, independently of the associations performed before the detection of this event.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: October 23, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
    Inventors: Ryad Benosman, Siohoi Ieng, Stephane Regnier, Ni Zhenjiang
  • Patent number: 10109883
    Abstract: The invention relates to novel polymers containing grafted sodium or lithium sulphonamides, production methods thereof and uses of same as electrolytes in batteries.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: October 23, 2018
    Assignees: CPD INNOVATION, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'AIX MARSEILLE
    Inventors: Jean-Roger Desmurs, Elisabet Dunach Clinet, Philippe Knauth, Vincent Morizur, Sandra Olivero
  • Patent number: 10106565
    Abstract: Dendrimers with monophosphonic or bisphosphonic terminations for the treatment of inflammatory diseases.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: October 23, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE PAUL SABATIER (TOULOUSE III)
    Inventors: Mary Poupot, Remy Poupot, Jean-Jacques Fournie, Damien Portevin, Severine Fruchon, Jean-Luc Davignon, Cedric-Olivier Turrin, Anne-Marie Caminade, Jean-Pierre Majoral, Olivier Rolland
  • Patent number: 10099987
    Abstract: Disclosed is a process for preparing a product of formula I: wherein the reaction is catalyzed both by thiamine or a thiamine salt and by ascorbic acid in a form which is free or salified or an organic acid salt of an alkaline metal, preferably sodium acetate, potassium tartrate, sodium succinate, or a reductone, preferably 2-hydroxypropanedial or 2,3-dihydroxycyclopent-2-ene-1-one in an organic solvent.
    Type: Grant
    Filed: December 16, 2015
    Date of Patent: October 16, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE MONTPELLIER
    Inventors: Claude Grison, Vincent Escande, Andrii Stanovych
  • Patent number: 10102956
    Abstract: Disclosed is a system (10) for generating skyrmions, including: a gun (12) including a wall-forming region (14) made from a first material, the region (14) defining an outer space (16) made from a second material different from the first material and an inner space (18) made from a third material different from the first material, the second material and the third material being magnetic materials; and a magnetization reversal device (26) that can reverse the magnetization at the interface between the region (14) and the inner space (18).
    Type: Grant
    Filed: September 9, 2015
    Date of Patent: October 16, 2018
    Assignees: THALES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Vincent Cros, Noah Van Horne, Joao Sampaio, Albert Fert, Nicolas Reyren
  • Patent number: 10098984
    Abstract: A method of conferring modified properties, e.g. modified physical and/or biochemical properties, to a metallic substrate surface, including at least two steps being (i) a first step including at least exposing the substrate surface to a hetero-bifunctional anchoring molecule carrying at least a silane group and at least a A1 group, the A1 group being optionally introduced within the anchoring molecule via a preliminary functionalizing step, and (ii) a second step of exposing the substrate surface to a polymer carrying at least three groups A2 capable of reacting with A1 in a thiol-ene reaction, the number average molecular weight of the polymer being greater than 1 000 g/mol.
    Type: Grant
    Filed: November 19, 2013
    Date of Patent: October 16, 2018
    Assignees: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SORBONNE UNIVERSITÉ
    Inventors: Vincent Semetey, Anne-Sophie Castanet