Abstract: A medical device that includes a sheath, a tool within the sheath and movable relative to the sheath, and a handle including a rotation assembly configured to rotate the tool relative to the sheath in response to rotation of the rotation assembly relative to a portion of the handle. The rotation assembly rotates the tool relative to the sheath at predefined angular intervals and inhibits movement at each of the predefined angular intervals.

Abstract: Various apparatuses to attach a first medical device to a second medical device are described that allow the physician to grasp only a single device while the other device remains securely attached to the one being grasped. The apparatuses, once they are attached to the first medical device, are designed to be easily and quickly attached and detached to a second medical device, normally only requiring the use of one hand. Furthermore, the apparatuses oftentimes include a base that can easily couple and decouple from the portion that is attached to the second medical device so that if the need arises to separately use the second medical device, it can be decoupled from the first medical device without completely removing the apparatus from the second medical device.

Abstract: A laser system includes a first cavity to output a laser light along a first path, a first mirror to receive the laser light from the first cavity, and redirect the laser light along a second path that is different than the first path, a beam splitter removably located at a first position on the second path, a beam combiner removably located at a second position on the second path, and an alignment device having first and second alignment features. The first and second alignment features occupy the first position and the second position, respectively, on the second path, when the beam splitter and the beam combiner are removed from the first position and the second position.

Abstract: A method for coupling a first medical device component to a second medical device component includes altering the first medical device component from a natural state to an altered state, by reducing a cross-sectional dimension of the first medical device. The method further includes fitting a first portion of the first medical device component in the altered state into a first opening of the second medical device component. The first medical device component includes second portions not within the first opening of the second medical device component. The method further includes allowing the second portions of the first medical device component to revert back to the natural state.

Abstract: According to one aspect, a tissue fastening device may comprise a body configured to include a plurality of fasteners; an anvil rotatable relative to the body; and a tissue cutting device. The body may define a longitudinal channel configured to receive the tissue cutting device. The tissue fastening device may further comprise a fastener actuator configured to move proximally relative to the body to deploy the plurality of fasteners from the body; and an actuation wire coupled to the tissue cutting device and the fastener actuator. The actuation of the actuation wire may cause the fastener actuator to deploy at least one of the plurality of fasteners into tissue distally of tissue cut by the tissue cutting device.

Abstract: An endoscopic tissue fastening device may include a body having a first portion and a second portion arranged alongside the first portion. The second portion may extend distally of the first portion and may terminate in a distal end face of the body. The device may further include a tissue fastening assembly having a fastening head with a proximal end and a distal end. The fastening head may be deflectable at a location between the proximal end and the distal end of the fastening head. The tissue fastening assembly may be received within a lumen of the body. Further, the body may be moveable between an unarticulated configuration and an articulated configuration. In the articulated configuration, a central longitudinal axis of the second portion of the body may be substantially parallel with a central longitudinal axis of the tissue fastening assembly.

Abstract: The present disclosure relates generally to fluorescent imaging devices, systems, and methods for an endoscopic procedure, and in particular, indocyanine green (ICG) fluorescence. In some embodiments, a device for fluorescent imaging during an endoscopic procedure may include an attachment connectable to a distal end of an endoscope. The attachment may include a first filter alignable with a light source of the endoscope, and a second filter alignable with an imaging device of the endoscope. The first filter may be positionable such that in a first position the first filter is aligned with the light source, and in a second position the first filter is out of alignment with the light source. The second filter may be positionable such that in a first position the second filter is aligned with the imaging device, and in a second position the second filter is out of alignment with the imaging device.

Abstract: Transluminal access system includes a stent delivery catheter having a handle control mechanism. The catheter comprises a number of components for establishing an initial penetration between adjacent body lumens and subsequently implanting a stent or other luminal anchor therebetween. Manipulation of the stent components is achieved using control mechanisms on the handle while the handle is attached to an endoscope which provides access to a first body lumen.

Abstract: Medical systems are described, including a medical system includes a first medical device and a second medical device. The first medical device includes a handle and an insertion portion with a first working channel. A distal portion of the insertion portion of the first medical device includes a first tracking element and at least one camera. The second medical device includes a handle and an insertion portion. A distal portion of the insertion portion of the second medical device includes a second tracking element. The first tracking element is configured to provide a signal that indicates a position or orientation of the distal portion of the first medical device. The second tracking element is configured to provide a signal that indicates a position or orientation of the distal portion of the second medical device.

Abstract: Systems and methods for processing electronic images from a medical device comprise receiving an image frame from the medical device, and determining a first color channel and a second color channel in the image frame. A location of an electromagnetic beam halo may be identified by comparing the first color channel and second color channel. Edges of an electromagnetic beam may be determined based on the electromagnetic beam halo, and size metrics of the electromagnetic beam may be determined based on the edges of the electromagnetic beam. A visual indicator on the image frame may be displayed based on the size metrics of the electromagnetic beam.

Abstract: Medical systems are described, including a medical system that includes a scope including a handle and a shaft defining a channel having a distal opening, a processor, at least one laser source, a first laser fiber, and a second laser fiber, wherein each of the first laser fiber and the second laser fiber is coupled to the at least one laser source and extends through the shaft, wherein a distal end of the shaft includes an imager, the distal opening of the channel, a distal end of the first laser fiber, and a distal end of the second laser fiber, and wherein each of the first laser fiber and the second laser fiber is configured to transmit a collimated beam onto a target without altering or fragmenting the target.

Abstract: An apparatus for delivering a powdered agent into a subject's body may include a first passage for receiving a pressurized gas. The apparatus also may include a container housing a powdered agent. The container may be in fluid connection with the first passage. At least a portion of the pressurized gas is introduced into the powdered agent in the container to fluidize the powdered agent. The apparatus also may include a second passage for receiving the powdered agent from the container. In a first configuration of the apparatus, the second passage may not be in fluid connection with the container. In a second configuration of the apparatus, the second passage may be in fluid connection with the container. The apparatus may be configured to transition between the first configuration and the second configuration.

Abstract: A system including a controller to determine an in-body time of a medical device in a patient during a medical procedure. The controller to: receive signals from at least one temperature sensor; detect insertion of the medical device into the patient by one or more of determining the temperature of the medical device and determining the change of temperature of the medical device with respect to time; increment an in-body time counter to measure the in-body time of the medical device after detecting insertion of the medical device into the patient; detect that the medical device has been removed from the patient by determining that the change of temperature of the medical device with respect to time is negative; and stop incrementing the in-body time counter in response to detecting that the medical device has been removed.

Abstract: A device for fluidizing and delivering a powdered agent, including a canister extending longitudinally from a first to a second end and defining a space within which a powdered agent is received, an inlet coupleable to a gas source for supplying gas to the space to fluidize the powdered agent to create a fluidized mixture, an outlet via which the gas mixture is delivered to a target area, a tube extending from the outlet into the interior space, the tube including a slot extending through a wall thereof so that gas mixture is passable from the interior space through the outlet via the second end and the slot, and a door movably coupled to the tube so that the door is movable over the slot to control a size of the slot open to the interior space of the canister.

Abstract: Improved methods and devices for performing an endoscopic surgery are provided. Systems are taught for operatively treating gastrointestinal disorders endoscopically in a stable, yet dynamic operative environment, and in a minimally invasive manner. Such systems include, for example, an endoscopic surgical suite. The surgical suite can have a reversibly expandable retractor that expands to provide a stable, operative environment within a subject. The expansion can be selectively asymmetric to maximize space for a tool and an endoscope to visualize a target tissue and treat the target tissue from outside the patient in a minimally invasive manner.

Abstract: Described are methods of treating urinary incontinence using a urinary sling and a tissue path that passes through the obturator foramen, along with related surgical implants, devices, systems and kits.

Abstract: The present disclosure relates generally to devices, systems, and methods for coil embolization, and, more particularly, to use and methods of forming coated coils. In an aspect, an embolic system may include a coil having a proximal end, a distal end, and a length therebetween slidingly disposed within a sheath. A coating may be disposed about the coil. A delivery filament may be configured to be slidingly disposed within the sheath proximal of the coil such that the coil can be ejected from the distal end of the sheath into the working lumen of a microcatheter. The coating may be configured to substantially fracture as the coil transitions from being substantially aligned with a longitudinal axis of the microcatheter to substantially misaligned with the longitudinal axis of the microcatheter upon being ejected from the microcatheter. The coating may be configured to plasticize after being ejected into an aqueous environment.

Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: Systems, devices, and methods for electroporation ablation therapy are disclosed in the context of esophageal ablation. An ablation device may include a first catheter defining a longitudinal axis and a lumen therethrough. A balloon may be coupled to the first catheter. The balloon may be configured to transition between a deflated configuration and an inflated configuration. A second catheter may extend from a distal end of the first catheter lumen. A set of splines including electrodes formed on a surface of each of the splines may couple to the distal end of the first catheter lumen and a distal portion of the second catheter. The second catheter may be configured for translation along the longitudinal axis to transition the set of splines between a first configuration and a second configuration.

Abstract: A medical device includes an end effector at a distal end of the medical device, an actuator coupled to a proximal end of the end effector, a pivot arm pivotally coupled to the end effector distal of the proximal end of the end effector, where actuation of the actuator pivots the end effector relative to the pivot arm, and a lock on the end effector and the pivot arm, where the lock has a first state permitting the end effector to pivot relative to the pivot arm and a second state restricting the end effector from pivoting relative to the pivot arm.