Abstract: The present disclosure relates generally to the field of medical devices. In particular, the present disclosure relates to an assembly with an adjustable ultrasound port and flush port for lateral and axial positioning of a radial ultrasound probe within a patient.

Abstract: Embodiments herein relate to intravascular imaging display systems and related methods. In an embodiment, an intravascular imaging display system is included having a control circuit and a video output circuit. The video output circuit can be configured to generate a display output including a user interface. The user interface can include graphical elements related to a vessel being imaged. The graphical elements can include a first detected feature portion at least partially defined by a first graphic indicator and a second detected feature portion at least partially defined by a second graphic indicator. The first graphic indicator can be visually distinct from the second graphic indicator. The first detected feature portion and the second detected feature portion can be assigned to represent one or more locations along a vessel wall by the control circuit based on a degree of attenuation of an ultrasound return signal crossing a threshold value.

Abstract: Medical devices and methods for making, using, and treating medical devices are disclosed. An example method for treating a medical device is disclosed. The method may include disposing an annealing fluid in a closed chamber, allowing the annealing fluid to reach a liquid-gas equilibrium within the chamber, and disposing a drug coated medical device within the closed chamber.

Abstract: Computer systems and computer-implemented analysis methods may be used for assistance in planning and/or performing a medical procedure, such as percutaneous nephrolithotomy or percutaneous nephrolithotripsy. The method may include receiving one or more radiographic images of an anatomical structure of a patient, generating a display of the radiographic image(s), generating at least one request for user input to identify features of the anatomical structure, receiving user input identifying the features of the anatomical structure, identifying at least one access plan based on the received user input, and generating a display of the identified access plan(s) associated with the radiographic image(s). The method may include generating a patient template that indicates an insertion site according to the identified access plan(s).

Abstract: A medical device comprising a shaft, a handle including a proximal portion and a distal portion, wherein the distal portion is fixed to a proximal portion of the shaft, and a channel extending from the handle into the shaft, wherein the channel includes a proximal channel and a distal channel, the proximal channel being rotatable relative to the distal channel and aligned with the distal channel throughout rotation of the proximal channel, wherein the proximal portion includes the proximal channel and the distal portion includes the distal channel, wherein the distal portion is rotatable relative to the proximal portion of the handle, and the shaft is configured to rotate with the distal portion of the handle.

Abstract: A valve assembly for a medical device that includes a body having an inlet that is in fluid communication with a source of fluid, and an outlet that is in fluid communication with a delivery conduit of the medical device. The valve assembly includes a shuttle configured to move within the body between a first and second position to control delivery of fluid from the inlet to the outlet. In the first position, the shuttle is configured to maintain the fluid at a first pressure within the body and seal the outlet from the inlet, such that the delivery conduit is isolated from the fluid at the first pressure. In the second position, the shuttle is configured to maintain the fluid at a second pressure within the body and fluidly couple the outlet to the inlet, such that the delivery conduit receives the fluid at the second pressure.

Abstract: A medical device, comprising a tube having a sidewall defining a lumen within the tube, wherein a plurality of openings extend through a distal portion of the sidewall and are in fluid communication with the lumen; a support structure coupled to the distal portion of the sidewall, the support structure having a contracted configuration and an expanded configuration, and the support structure having support openings through a wall of the support structure; and a porous body over at least a portion of the support structure.

Abstract: Systems and methods for treating a stricture, for example along the biliary and/or pancreatic tract, are disclosed. An example system may include a handle having a base having a distal end region and a proximal end region. A length adjustment member may be coupled to the handle. A length actuator may be coupled to the distal end region of the handle. A catheter shaft may be coupled to the handle. A steering mechanism may be coupled to the handle. The steering mechanism may include an elongate steering member having a first end region coupled to the handle, a first body region extending along the catheter shaft, a loop region extending about the catheter shaft, a second body region extending along the catheter shaft, and a second end region coupled to the handle.

Abstract: A steerable device, such as a steerable catheter, may include a control handle and an insertion shaft extending outwardly therefrom. In use, the insertion shaft is navigated to an area of interest for examination and/or treatment thereof. The steerable device may include a steering system that controls the deflection angle of the distal end of the insertion shaft in two or more non-planar directions for navigating the insertion shaft to the area of interest. The steering system may also include a locking mechanism for arresting or partially arresting the movement of the distal end of the insertion shaft in a first direction independent of arresting or partially arresting the movement of the distal end in a second non-planar direction.

Abstract: A valve assembly that includes an inlet that is in fluid communication with an enclosure of a medical device, an outlet that is in fluid communication with a delivery conduit of the medical device, and a body having a channel that is in fluid communication with a source of fluid. The body is configured to move relative to the inlet and outlet to selectively fluidly couple the channel with the enclosure and delivery conduit. In a first position of the body, the channel is misaligned with at least one of the inlet or the outlet, such that the delivery conduit is not in fluid communication with at least one of the enclosure or the source of fluid. In a second position of the body, the channel is aligned with the inlet and outlet such that the delivery conduit is in fluid communication with the enclosure and the source of fluid.

Abstract: The techniques described herein relate to a laser system, including: a plurality of fiber laser amplifiers; a beam combiner configured to combine laser light outputs from the plurality of fiber laser amplifiers; an optical delivery fiber configured to receive the combined output from the plurality of laser amplifiers into the delivery fiber and configured to deliver the combined output to a target; one or more diode lasers configured for providing optical pump pulses to the plurality of fiber laser amplifiers, wherein the laser light outputs from the plurality of fiber laser amplifiers are generated in response to the provided optical pump pulses.

Abstract: In one aspect of the present disclosure, a device may include a shaft having a distal end, and a tip at the distal end of the shaft. The tip may include an opening defined by a surface of the tip. An instrument inserted through the shaft may extend distally out of the opening. The device also may include an elevator for engaging the instrument. The elevator may include a proximal end fixed relative to the surface of the tip, a proximal portion extending distally from the proximal end, and a distal portion extending distally from the proximal portion. A force exerted on the elevator bends the proximal portion to deflect the distal portion without bending of the distal portion.

Abstract: In some embodiments, the present disclosure pertains to a unit dose pack for forming a bath for cleaning medical instruments. The unit dose pack may comprise at least a first chamber that contains an enzymatic detergent composition comprising one or more enzymes, the first chamber being formed from at least one first sheet of material that comprises a water-soluble film, and the at least one first sheet of material encapsulating the enzymatic detergent composition, wherein upon immersion in water, the enzymatic detergent composition is released from the first chamber into the water. In other embodiments, the present disclosure pertains to a method of cleaning a medical instrument using at least one such unit dose pack. In some embodiments, the medical instrument is an endoscope.

Abstract: Several embodiments of the present invention are generally directed to medical visualization systems that comprise combinations of disposable and reusable components, such as catheters, functional handles, hubs, optical devices, etc. Other embodiments of the present invention are generally directed to features and aspects of an in-vivo visualization system that comprises an endoscope having a working channel through which a catheter having viewing capabilities is routed. the catheter may obtain viewing capabilities by being constructed as a vision catheter or by having a fiberscope or other viewing device selectively routed through one of its channels. The catheter is preferably of the steerable type so that the distal end of the catheter may be steered from its proximal end as it is advanced with the body. A suitable use for the in-vivo visualization system includes but is not limited to diagnosis and/or treatment of the duodenum, and particularly the biliary tree.

Abstract: A photoacoustic catheter adapted for placement within a blood vessel having a vessel wall includes an elongate shaft, a balloon and a photoacoustic transducer. The elongate shaft can extend from a proximal region to a distal region. The elongate shaft can include a light guide that is configured to be placed in optical communication with a light source. The balloon is coupled to the elongate shaft, and can be configured to expand from a collapsed configuration suitable for advancing the photoacoustic catheter through a patient's vasculature to a first expanded configuration suitable for anchoring the photoacoustic catheter in position relative to a treatment site. The photoacoustic transducer can be disposed on a surface of the balloon and in optical communication with the light guide. The photoacoustic transducer can include a light-absorbing material and a thermal expansion material.

Abstract: In some aspects, the present disclosure pertains to multi-arm polymers that comprise a core and a plurality of polymer segments having a first end that is covalently attached to the core and (a) a second end comprising a moiety that comprises a reactive end group, wherein the polymer segments comprise one or more hydrophilic aprotic NMP-polymerizable monomers, and wherein the reactive multi-arm polymer comprises nitroxide radicals or (b) a second end comprising a moiety that comprises an alkoxyamine group, wherein the core is a polyol residue, and wherein the polymer segments comprise one or more NMP-polymerizable monomers. In some aspects, the present disclosure pertains to a multifunctional alkoxyamine molecule comprising a core and a plurality of alkoxyamine groups covalently attached to the core, wherein the core is a polyol residue.

Abstract: A medical system includes an insertion device including a handle, an insertion portion with at least one lumen, a port fluidly coupled to the lumen, and a connection portion. The medical system also includes a medical device including a handle, an insertion portion, and a connection portion configured to be coupled to the connection portion of the insertion device. The connection portion of the medical device is configured to be coupled to the connection portion of the insertion device to form an electronic and physical connection between the insertion device and the medical device.

Abstract: A medical device including an attachment device having a longitudinal axis, a pivot arm having a first end pivotally attached to the attachment device, an end effector pivotally attached to a second end of the pivot arm and configured to move from a first configuration to a second configuration, and a longitudinally extending body attached to a proximal end of the end effector. Movement of the longitudinally extending body in a proximal direction rotates the end effector from the first configuration to the second configuration, the end effector is approximately parallel to the longitudinal axis of the attachment device in the first configuration, and the end effector is angled relative to the longitudinal axis of the attachment device in the second configuration.

Abstract: Various embodiments are generally directed to devices, systems, and methods for controlling the flow of fluids in endoscopic systems, such as endoscopic ultrasound (EUS) enabled endoscopes. Some embodiments are particularly directed to valve sets and/or valve interface mechanisms for controlling air, water, and/or suction flow through a valve well for an endoscopic system. Several embodiments are directed to user interface mechanisms and techniques for enabling an operator to interact with and control endoscope valves. Many embodiments are directed to mechanisms and techniques for translating interface input motion into valve control motions. In one or more embodiments, the valve sets and/or valve interface mechanisms may be disposable.

Abstract: A laser system may include a laser resonator configured to emit an input laser beam having an elliptical cross-sectional shape. The laser system also may include first reflective device configured to reflect the input laser beam to produce a first reflected laser beam. The first reflective device may include a spherical surface for reflecting the input laser beam. The laser system also may include a second reflective device configured to reflect the first reflected laser beam to produce a second reflected laser beam. The laser system also may include a coupling device configured to focus the second reflected laser beam to produce an output laser beam. The coupling device may include a spherical surface for receiving the second reflected laser beam. The laser system also may include an optic fiber configured to transmit the output laser beam for emission of the output laser beam onto a target area.