Patents Assigned to Scinopharm Taiwan, Ltd.
  • Process for preparing aromatase inhibitors
    Publication number: 20080275259
    Abstract: A process of making an aromatase inhibitor of formula (I) wherein each of R1, R2, R3, and R4, independently, is hydrogen, halogen, or C1-C6 alkyl, comprising reacting a compound of formula (II) with an acid in the presence of a suitable solvent. A new crystalline form of exemestane and is also disclosed.
    Type: Application
    Filed: April 30, 2008
    Publication date: November 6, 2008
    Applicant: ScinoPharm Taiwan, Ltd
    Inventors: WeiYu Chen, Shu-Ping Chen
  • Crystalline forms of topotecan hydrochloride and processes for making the same
    Publication number: 20080269493
    Abstract: Novel crystalline forms of topotecan hydrochloride and processes of making the same are disclosed.
    Type: Application
    Filed: April 14, 2008
    Publication date: October 30, 2008
    Applicant: ScinoPharm Taiwan Ltd.
    Inventors: Tsung-Cheng Hu, Piin-Jye Harn, Shu-Ping Chen, Chia-Lin Charlene Shieh
  • Crystal forms of irinotecan hydrochloride
    Patent number: 7435818
    Abstract: The present invention provides for novel crystalline forms of irinotecan hydrochloride and processes for their preparation, pharmaceutical compositions containing the novel forms and methods for treating metastatic carcinoma of the colon or rectum using same.
    Type: Grant
    Filed: September 19, 2006
    Date of Patent: October 14, 2008
    Assignee: Scinopharm Taiwan, Ltd.
    Inventors: Shu-Ping Chen, Piin-Jye Harn
  • Resolution of a narwedine amide derivative
    Patent number: 7307162
    Abstract: The present invention provides for an efficient method of effecting the resolution of a narwedine amide, and the synthesis of galantamine.
    Type: Grant
    Filed: September 27, 2004
    Date of Patent: December 11, 2007
    Assignee: ScinoPharm Taiwan, Ltd.
    Inventors: George Schloemer, Tsung-Yu Hsiao
  • Monoclonal antibody with the capability of neutralizing enterovirus type 71 infection
    Publication number: 20060292693
    Abstract: The present invention provides a monoclonal antibody capable of neutralizing EV71 infection.
    Type: Application
    Filed: April 12, 2006
    Publication date: December 28, 2006
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: Jui-Hung Yen, Hung-Jung Wang, Huan Lei, Chun-Keung Yu, Ya-Fang Wang
  • Process for the preparation of 7-alkyl-10-hydroxy-20(S)-camptothecin
    Patent number: 7151179
    Abstract: The key intermediate in any synthesis of Irinotecan is 7-ethyl-10-hydroxy-20(S)-camptothecin. A process for the efficient synthesis of this intermediate is demonstrated proceeding through readily available 20(S)-camptothecin. Various other tecan compounds may be made by use of corresponding 7-alkyl-10-hydroxy-20(S)-camptothecin intermediates.
    Type: Grant
    Filed: May 12, 2004
    Date of Patent: December 19, 2006
    Assignee: Scinopharm Taiwan, Ltd.
    Inventors: Chien-Hsing Lin, Yung-Fa Chen, Kau-Ming Chen
  • Process for the preparation imidazo[1,2-A]pyridine-3-acetamides
    Patent number: 6861525
    Abstract: The present invention relates to an improved synthesis of imidazo[1,2-a]pyridine-3-N,N-dialkylacetamides, including zolpidem tartrate.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: March 1, 2005
    Assignee: Scinopharm Taiwan, Ltd.
    Inventor: George C. Schloemer
  • Process for the preparation of 7-alkyl-10-hydroxy-20(S)-camptothecin
    Publication number: 20040235878
    Abstract: The key intermediate in any synthesis of Irinotecan is 7-ethyl-10-hydroxy-20(S)-camptothecin. A process for the efficient synthesis of this intermediate is demonstrated proceeding through readily available 20(S)-camptothecin. Various other tecan compounds may be made by use of corresponding 7-alkyl-10-hydroxy-20(S)-camptothecin intermediates.
    Type: Application
    Filed: May 12, 2004
    Publication date: November 25, 2004
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: Chien-Hsing Lin, Yung-Fa Cheng, Kau-Ming Cheng
  • Process for the preparation imidazo[1,2-A]pyridine-3-acetamides
    Publication number: 20040010146
    Abstract: The present invention relates to an improved synthesis of imidazo[1,2-a]pyridine-3-N,N-dialkylacetamides, including zolpidem tartrate.
    Type: Application
    Filed: July 14, 2003
    Publication date: January 15, 2004
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventor: George C. Schloemer
  • Asymmetric synthesis of a key intermediate for making benazepril and analogues thereof
    Patent number: 6548665
    Abstract: The present invention provides a method of converting an intermediate compound to the desired S,S diastereomer for efficiently making benazepril and analogues thereof.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: April 15, 2003
    Assignee: Scinopharm, Taiwan, Ltd.
    Inventors: Wei-Hong Tseng, George Schloemer
  • Kinetic resolution of a intermediate useful in the production of benazepril and analogues thereof
    Publication number: 20030055245
    Abstract: The present invention provides an efficient synthetic process for making benazepril and analogues thereof by having an intermediate compound undergo epimerization and kinetic resolution.
    Type: Application
    Filed: May 21, 2002
    Publication date: March 20, 2003
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: Wei-Hong Tseng, Kau-Ming Cheng, George Schloemer, Chien-Wen Chen, Chih-Wen Cheng
  • Process for making taxane derivatives
    Patent number: 6531611
    Abstract: The present invention provides a novel semi-synthetic method of producing a variety of novel taxane derivatives. The method involves the reaction of a phenylisoserine derivative with a suitably blocked Baccatin III derivative to produce a taxane substrate that may be further modified to form Pactitaxel and other potentially useful taxane derivatives.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: March 11, 2003
    Assignee: Scinopharm Taiwan, Ltd.
    Inventors: George Schloemer, Yung-Fa Chen, Chien Hsin Lin, Wlodzimierz Daniewski
  • ASYMMETRIC SYNTHESIS OF A KEY INTERMEDIATE FOR MAKING BENAZEPRIL AND ANALOGUES THEREOF
    Publication number: 20020183515
    Abstract: The present invention provides a method of converting an intermediate compound to the desired S,S diastereomer for efficiently making benazepril and analogues thereof.
    Type: Application
    Filed: July 19, 2001
    Publication date: December 5, 2002
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: Wei-Hong Tseng, George Schloemer
  • Process for the preparation of conjugated estrogens from pregnant mare urine
    Publication number: 20020156303
    Abstract: This invention is directed to a process for the preparation of conjugated estrogens from pregnant mare urine (PMU), comprising the steps of
    Type: Application
    Filed: April 19, 2001
    Publication date: October 24, 2002
    Applicant: SCINOPHARM TAIWAN, LTD.
    Inventors: Vallapa Soong, Jing-Yi Wang
  • Process for making taxane derivatives
    Publication number: 20020137955
    Abstract: The present invention provides a novel semi-synthetic method of producing a variety of novel taxane derivatives. The method involves the reaction of a phenylisoserine derivative with a suitably blocked Baccatin III derivative to produce a taxane substrate that may be further modified to form Pactitaxel and other potentially useful taxane derivatives.
    Type: Application
    Filed: March 23, 2001
    Publication date: September 26, 2002
    Applicant: ScinoPharm Taiwan, Ltd.
    Inventors: George Schloemer, Yung-Fa Chen, Chien Hsin Lin, Wlodzimierz Daniewski