Patents Assigned to Seoul National University Hospital
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Publication number: 20240362242Abstract: Provided are a method and apparatus for proposing a solution, based on a survey. The method includes storing indicators in a data format in a database, wherein each of the indicators is transformed from a pattern of responses of respondents related to an issue, transforming a response of a user to the survey to a patterned response, the patterned response in the data format, selecting an indicator to be compared with the patterned response among the indicators, the indicators and the patterned response are being in the same data format, determining one or more issues, based on a comparison of the patterned response and the selected indicator, determining a proposal solution set, based on the one or more issues, and displaying the one or more issues and the proposal solution set on a device of the user.Type: ApplicationFiled: April 25, 2024Publication date: October 31, 2024Applicants: SEOUL NATIONAL UNIVERSITY HOSPITAL, INVITES BIOCORE CO., LTD.Inventor: Ju Won LIM
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Patent number: 12121740Abstract: A system for inducing synthesis of Vitamin D in a body includes a wearable illumination device formed in a structure that is wearable on the body, and including a plurality of light sources configured to radiate an ultraviolet light to a skin of a worn part; and a control device connected to the plurality of light sources and configured to drive the plurality of light sources to radiate the ultraviolet light, wherein the wearable illumination device includes a light diffusion panel configured to equalize an irradiance of the ultraviolet light reaching the skin by causing diffusion of the ultraviolet light radiated from the plurality of light sources.Type: GrantFiled: January 28, 2022Date of Patent: October 22, 2024Assignees: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, SEOUL NATIONAL UNIVERSITY HOSPITAL, GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Seunghyup Yoo, Jaehyeok Park, Hanul Moon, Sunhyoung Koo, Changhun Seok, Dongho Choi, Hyuk Joo Lee, In-Young Yoon, Jun Seok Ahn, Ji Su Choi, Jung Kyung Hong, Tae Kim, Jiseung Kang, Jieun Jung
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Publication number: 20240335170Abstract: Embodiments relate to a system and method for electrocardiogram image-based patient evaluation, wherein: a source electrocardiogram image of a target patient is acquired by a user terminal; a server is requested by the user terminal to evaluate the target patient, the request including the source electrocardiogram image; electrocardiogram image-based evaluation information of the patient is generated by the server, the evaluation information of the target patient is transmitted to the user terminal; and reported feedback based on the evaluation information of the target patient is provided by the user terminal.Type: ApplicationFiled: April 15, 2022Publication date: October 10, 2024Applicant: Seoul National University HospitalInventor: Joonghee Kim
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Patent number: 12109123Abstract: An intervertebral fusion cage is disclosed. An intervertebral fusion cage according to an embodiment of the present invention comprises: a body including a receiving part of which upper and lower portions are open, an upper guide part, and a lower guide part; a moving member disposed in the receiving part; a screw which is screw-coupled to the body and moves forwards or backwards relative to the body integrally with the moving member when rotating; an upper plate which has a guided part guided by the upper guide part and is disposed above the body while being engaged with the moving member; and a lower plate which has a guided part guided by the lower guide part and is disposed under the body while being engaged with the moving member.Type: GrantFiled: September 29, 2020Date of Patent: October 8, 2024Assignees: CG BIO CO., LTD., SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Ui Su Jung, Seung Jae Hyun
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Publication number: 20240255747Abstract: Provided is a photographing apparatus including an image capturing unit including a first light source, an object lens, and a first light detector, a surface detecting unit including a second light source, the object lens, and a second light detector, a processor configured to obtain a strong reflection signal area where a reflection signal is strong in an oblique plane image obtained from the second light detector, and obtain a relative position relationship between a region of interest and a focal plane of the object lens, and an actuator configured to adjust the region of interest to be in focus.Type: ApplicationFiled: December 7, 2023Publication date: August 1, 2024Applicants: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION, SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Ki Hean KIM, Chang Ho Yoon, Jungbin Lee, Soohyun Park, Seonghan Kim, Kyungbin Bae
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Patent number: 12033299Abstract: There is provided a user interaction training system. The user interaction training system comprises: a photographing device configure to photograph an original image including a first object at a plurality of photographing angles; an image warping device configured to receive an image including a second object corresponding to a user and the original image including the first object photographed by the photographing device, and to generate a converted image converting the first object into a third object different from the first object based on characteristic information of the second object by using a pre-trained image warping model; and a display device configured to display the generated converted image.Type: GrantFiled: September 23, 2022Date of Patent: July 9, 2024Assignee: SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Soonbum Hong, Hyoun-Joong Kong
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Publication number: 20240197816Abstract: A treatment of rejection of a transplant by a recipient of the transplant is disclosed. Methods for prolonging transplant survival in a recipient of the transplant, prolonging survival of the recipient, delaying and/or suppressing delayed graft function in the recipient, and/or reducing the amount of an immunosuppressant administered for transplantation. The methods include providing the transplant with a CHP or a pharmaceutically acceptable salt thereof is disclosed. Also provided is a method for the production of a pharmaceutical composition for the treatment of a transplant allowing modulating transplant survival in a recipient of the transplant.Type: ApplicationFiled: December 8, 2023Publication date: June 20, 2024Applicants: NovMetaPharma Co., Ltd., Seoul National University R&DB Foundation, SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Seung Hee Yang, Hoeyune Jung, Jong Min Kim, Yon Su Kim, Heonjong Lee
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Patent number: 11999952Abstract: The present invention relates to an artificially manipulated neovascularization-associated factor for regulating neovascularization and a use thereof. More particularly, the present invention relates to a system for artificially regulating neovascularization, which includes an artificially manipulated neovascularization-associated factor for regulating neovascularization and/or a composition for artificially manipulating the neovascularization-associated factor. In a specific aspect, a neovascularization regulatory system including a neovascularization-associated factor such as artificially manipulated VEGFA, HIF1A, ANGPT2, EPAS1, or ANGPTL4 and/or an expression product thereof is provided.Type: GrantFiled: April 21, 2021Date of Patent: June 4, 2024Assignees: TOOLGEN INCORPORATED, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, SEOUL NATIONAL UNIVERSITY HOSPITAL, INSTITUTE FOR BASIC SCIENCEInventors: Jeong Hun Kim, Sung Wook Park, Seokjoong Kim, Dong Woo Song
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Patent number: 11996184Abstract: Some embodiments of the present disclosure provide a pneumothorax detection method performed by a computing device. The method may comprise obtaining predicted pneumothorax information, predicted tube information, and a predicted spinal baseline with respect to an input image from a trained pneumothorax prediction model; determining at least one pneumothorax representative position for the predicted pneumothorax information and at least one tube representative position for the predicted tube information, in a prediction image in which the predicted pneumothorax information and the predicted tube information are displayed; dividing the prediction image into a first region and a second region by the predicted spinal baseline; and determining a region in which the at least one pneumothorax representative position and the at least one tube representative position exist among the first region and the second region.Type: GrantFiled: December 22, 2022Date of Patent: May 28, 2024Assignees: LUNIT INC., SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Min Chul Kim, Chang Min Park, Eui Jin Hwang
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Publication number: 20240074827Abstract: A headset of a surgical robot system includes an endoscope image transmission module configured to transmit an endoscope image to a main screen, a surgical assist function transmission module configured to transmit a selected and activated surgical assist function on an auxiliary screen positioned at one side of the main screen, a surgical assist function optional transmission module configured to transmit a list of a plurality of surgical assist functions to be provided on the auxiliary screen to a selection screen, an acceleration sensor and a gyroscope, configured to detect a change in a position of a head of a user, an eye tracking module configured to detect a change in a user gaze and a change in focus, and a controller configured to control a specific surgical assist function selected from among the plurality of surgical assist functions to be provided to the auxiliary screen.Type: ApplicationFiled: February 16, 2023Publication date: March 7, 2024Applicants: Seoul National University Hospital, Seoul National University R&DB FoundationInventors: Sungwan KIM, Minwoo CHO, Jonghyeon LEE, Young Gyun KIM, Byeong Soo KIM, Dan YOON
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Publication number: 20240077996Abstract: A medical treatment system includes a transparent display located between a patient and a medical staff and configured to display, a plurality of interface, first and second gaze trackers respectively mounted on both sides of the transparent display to detect pupils of the medical staff and patient and configured to acquire positional coordinates of the pupils of the medical staff and patient in a three-dimensional space, a region setting unit configured to set a gaze exchange region based on an intersection point where a virtual connection line between the positional coordinates of the pupils of the medical staff and patient intersects a plane of the transparent display, and a control unit configured to rearrange the plurality of interface windows by moving at least one interface window overlapping the gaze exchange region outside the gaze exchange region.Type: ApplicationFiled: December 30, 2021Publication date: March 7, 2024Applicant: SEOUL NATIONAL UNIVERSITY HOSPITALInventor: Hyoun Joong KONG
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Publication number: 20240060992Abstract: The present disclosure relates to a kit and an information providing method capable of predicting or diagnosing a cause-specific therapeutic effect of sensorineural hearing loss. The kit and the method according to one aspect of the present invention can diagnose a cause-specific therapeutic effect of sensorineural hearing loss at an early stage and allow selection of the most appropriate treatment method.Type: ApplicationFiled: October 30, 2023Publication date: February 22, 2024Applicants: Seoul National University Hospital, The Industry & Academic Cooperation in Chungnam National University (IAC)Inventors: Byung Yoon Choi, Bong Jik Kim
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Patent number: 11845951Abstract: The present invention relates to a composition for gene manipulation for treating or improving a retinal dysfunction disease or a method using the same. More particularly, the present invention relates to a composition for gene manipulation including a guide nucleic acid capable of targeting a retinal function-forming gene and a method of treating or improving a disease caused by retinal dysfunction by artificially manipulating and/or correcting a retinal function-forming gene using the same.Type: GrantFiled: September 28, 2018Date of Patent: December 19, 2023Assignees: TOOLGEN INCORPORATED, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Dong Woo Song, Jung Min Lee, Un Gi Kim, Jeong Hun Kim, Dong Hyun Jo
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Patent number: 11785922Abstract: Provided are a protein complex in which estrogen receptor 2 (-ERT2) is fused to CRISPR associated protein 9 (Cas9), and a recombinant vector carrying a gene coding the protein complex, wherein ERT2 is bonded to the N-terminus and C-terminus of nuclear localization sequence (NLS)-removed Cas9 and the complex has the advantage of translocating from the cytosol into the nucleus at a certain time point upon treatment with tamoxifen and modifying a specific DNA with the aid of guide RNA (gRNA), ultimately enabling a more elaborate DNA modification operation in a desired part at a desired time point.Type: GrantFiled: May 3, 2018Date of Patent: October 17, 2023Assignee: SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Eun Ju Lee, Hyo-Soo Kim
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Patent number: 11771318Abstract: The present invention relates to a method for supporting reading of a fundus image of a subject, and a computing device using the same. Specifically, the computing device according to the present invention acquires the fundus image of the subject, extracts attribute information from the fundus image on the basis of a machine learning model for extracting the attribute information of the fundus image, and provides the extracted attribute information to an external entity. In addition, when evaluation information on the extracted attribute information or modification information on the attribute information is acquired, the computing device according to the present invention can also update the machine learning model on the basis of the acquired evaluation information or modification information.Type: GrantFiled: July 18, 2018Date of Patent: October 3, 2023Assignees: VUNO, INC., SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Sang Jun Park, Joo Young Shin, Jae Min Son, Sang Keun Kim, Kyuhwan Jung, Hyun-Jun Kim
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Publication number: 20230296583Abstract: Provided are an apparatus for diagnosing a disease and a method for diagnosing same. The apparatus includes a pump for pumping respiratory gas, a first pre-treatment portion connected to the pump and removing moisture and bad breath in the respiratory gas, and a volatile organic compound detector connected between the first pre-treatment portion and the pump and detecting volatile organic compounds in the respiratory gas.Type: ApplicationFiled: October 31, 2022Publication date: September 21, 2023Applicants: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Dae-Sik LEE, Sang Hoon JHEON, Hyung-Kun LEE, Yoohwa HWANG, Doyeob KIM, Chang-Beom KIM, Jin Oh LEE
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Publication number: 20230288582Abstract: The disclosure relates to a device for detecting therapeutic radiation based on an optical disk with solar cells. The radiation detecting device may include at least one optical disk formed of a water-equivalent material, disposed perpendicular to a first direction in which the radiation is incident, and converting the radiation into visible light; a solar cell disposed on one side of the at least one optical disk, converting the visible light into an electrical signal; and a processing module for collecting and processing the electrical signal outputted from the solar cell.Type: ApplicationFiled: March 10, 2023Publication date: September 14, 2023Applicants: NATIONAL CANCER CENTER, SEOUL NATIONAL UNIVERSITY HOSPITALInventors: Dongho SHIN, Tae Hyun KIM, Tae-Ho KIM, Haksoo KIM, Dong-Seok SHIN, Se Byeong LEE, Youngkyung LIM, Jonghwi JEONG, Jaeman SON
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Patent number: 11744461Abstract: The present disclosure relates to a retina imaging method in which a light from a light source into two lights is dispersed, at least one eyeground image of the eyeball at a first magnification is obtained by adjusting the paths of the two lights incident on the eyeball, and a plurality of DIC images are obtained at a second magnification higher than the first magnification with respect to the retina of the entirety of the obtained at least one eyeground image by adjusting the paths of the two lights incident on the eyeball.Type: GrantFiled: February 26, 2020Date of Patent: September 5, 2023Assignees: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, SEOUL NATIONAL UNIVERSITY HOSPITAL, INHA UNIVERSITY RESEARCH AND BUSINESS FOUNDATIONInventors: Jae Hun Kim, Dae Yu Kim, Seok Hwan Kim, Youngho Cho, Byeongho Park, Hyo-suk Kim, Subeen Park, Kyoung Min Lee
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Publication number: 20230248665Abstract: Provided is a composition comprising a dimethylchalcone derivative for prevention or treatment of metabolic diseases and, more specifically, to a compositioncomprising a derivative of 2?,4?-dihydroxy-6?-methoxy-3?,5?-dimethylchalcone as an active ingredient for the alleviation, prevention, or treatment of various metabolic diseases.Type: ApplicationFiled: March 16, 2023Publication date: August 10, 2023Applicants: SEOUL NATIONAL UNIVERSITY R & DB FOUNDATION, SEOUL NATIONAL UNIVERSITY HOSPITAL, CHUNG-ANG UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Kyong Soo PARK, Sung Soo CHUNG, Ji Seon LEE, Kwang Yong PARK
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Publication number: 20230235405Abstract: A marker composition, a kit, a gene panel, and a method which are for providing information for predicting the occurrence of, diagnosing, or treating age-related macular degeneration are disclosed. The marker composition, kit, gene panel, and method are novel tools that can provide information for predicting the occurrence of, diagnosing, or treating age-related macular degeneration, and has excellent sensitivity and can be easily analyzed without the use of a biopsy, and thus can be effectively used for the early diagnosis of age-related macular degeneration.Type: ApplicationFiled: February 21, 2023Publication date: July 27, 2023Applicants: Genome Opinion Inc., Seoul National University HospitalInventors: Choong Hyun Sun, Su Gyeong Kim, Ho Gune Im, Han Song, Baek Lok Oh, Su-Yeon Choi