Abstract: A medical treatment system includes a transparent display located between a patient and a medical staff and configured to display, a plurality of interface, first and second gaze trackers respectively mounted on both sides of the transparent display to detect pupils of the medical staff and patient and configured to acquire positional coordinates of the pupils of the medical staff and patient in a three-dimensional space, a region setting unit configured to set a gaze exchange region based on an intersection point where a virtual connection line between the positional coordinates of the pupils of the medical staff and patient intersects a plane of the transparent display, and a control unit configured to rearrange the plurality of interface windows by moving at least one interface window overlapping the gaze exchange region outside the gaze exchange region.

Abstract: A headset of a surgical robot system includes an endoscope image transmission module configured to transmit an endoscope image to a main screen, a surgical assist function transmission module configured to transmit a selected and activated surgical assist function on an auxiliary screen positioned at one side of the main screen, a surgical assist function optional transmission module configured to transmit a list of a plurality of surgical assist functions to be provided on the auxiliary screen to a selection screen, an acceleration sensor and a gyroscope, configured to detect a change in a position of a head of a user, an eye tracking module configured to detect a change in a user gaze and a change in focus, and a controller configured to control a specific surgical assist function selected from among the plurality of surgical assist functions to be provided to the auxiliary screen.

Abstract: The present disclosure relates to a kit and an information providing method capable of predicting or diagnosing a cause-specific therapeutic effect of sensorineural hearing loss. The kit and the method according to one aspect of the present invention can diagnose a cause-specific therapeutic effect of sensorineural hearing loss at an early stage and allow selection of the most appropriate treatment method.

Abstract: The present invention relates to a composition for gene manipulation for treating or improving a retinal dysfunction disease or a method using the same. More particularly, the present invention relates to a composition for gene manipulation including a guide nucleic acid capable of targeting a retinal function-forming gene and a method of treating or improving a disease caused by retinal dysfunction by artificially manipulating and/or correcting a retinal function-forming gene using the same.

Abstract: Provided are a protein complex in which estrogen receptor 2 (-ERT2) is fused to CRISPR associated protein 9 (Cas9), and a recombinant vector carrying a gene coding the protein complex, wherein ERT2 is bonded to the N-terminus and C-terminus of nuclear localization sequence (NLS)-removed Cas9 and the complex has the advantage of translocating from the cytosol into the nucleus at a certain time point upon treatment with tamoxifen and modifying a specific DNA with the aid of guide RNA (gRNA), ultimately enabling a more elaborate DNA modification operation in a desired part at a desired time point.

Abstract: The present invention relates to a method for supporting reading of a fundus image of a subject, and a computing device using the same. Specifically, the computing device according to the present invention acquires the fundus image of the subject, extracts attribute information from the fundus image on the basis of a machine learning model for extracting the attribute information of the fundus image, and provides the extracted attribute information to an external entity. In addition, when evaluation information on the extracted attribute information or modification information on the attribute information is acquired, the computing device according to the present invention can also update the machine learning model on the basis of the acquired evaluation information or modification information.

Abstract: Provided are an apparatus for diagnosing a disease and a method for diagnosing same. The apparatus includes a pump for pumping respiratory gas, a first pre-treatment portion connected to the pump and removing moisture and bad breath in the respiratory gas, and a volatile organic compound detector connected between the first pre-treatment portion and the pump and detecting volatile organic compounds in the respiratory gas.

Abstract: The disclosure relates to a device for detecting therapeutic radiation based on an optical disk with solar cells. The radiation detecting device may include at least one optical disk formed of a water-equivalent material, disposed perpendicular to a first direction in which the radiation is incident, and converting the radiation into visible light; a solar cell disposed on one side of the at least one optical disk, converting the visible light into an electrical signal; and a processing module for collecting and processing the electrical signal outputted from the solar cell.

Abstract: The present disclosure relates to a retina imaging method in which a light from a light source into two lights is dispersed, at least one eyeground image of the eyeball at a first magnification is obtained by adjusting the paths of the two lights incident on the eyeball, and a plurality of DIC images are obtained at a second magnification higher than the first magnification with respect to the retina of the entirety of the obtained at least one eyeground image by adjusting the paths of the two lights incident on the eyeball.

Abstract: Provided is a composition comprising a dimethylchalcone derivative for prevention or treatment of metabolic diseases and, more specifically, to a compositioncomprising a derivative of 2?,4?-dihydroxy-6?-methoxy-3?,5?-dimethylchalcone as an active ingredient for the alleviation, prevention, or treatment of various metabolic diseases.

Abstract: A marker composition, a kit, a gene panel, and a method which are for providing information for predicting the occurrence of, diagnosing, or treating age-related macular degeneration are disclosed. The marker composition, kit, gene panel, and method are novel tools that can provide information for predicting the occurrence of, diagnosing, or treating age-related macular degeneration, and has excellent sensitivity and can be easily analyzed without the use of a biopsy, and thus can be effectively used for the early diagnosis of age-related macular degeneration.

Abstract: A composition suitable for diagnosing a musculoskeletal disease and a composition suitable for preventing or treating a musculoskeletal disease are disclosed. The composition contains zinc finger protein with KRAB and SCAN domains 8 (Zkscan8) protein, which can be effectively used as an excellent biomarker for obtaining accurate information about the occurrence and progression stages of a musculoskeletal disease, specifically a tendon disease or a ligament disease. The compositions containing Zkscan8 can be effectively used for preventing or treating a musculoskeletal disease through Zkscan8 overexpression.

Abstract: The present invention relates to a unit drug conjugate wherein a binding group capable of binding to another unit drug conjugate is additionally linked to a unit drug conjugate in which a targeting substance, which binds specifically to target cells, and a drug, are linked together. When the unit drug conjugates according to the present invention are sequentially administered in vivo, complexes form a cluster by in vivo crosslinking, and the cluster promotes endocytosis of the drug conjugate, thereby significantly enhancing cellular internalization of the drug included in the drug conjugate.

Abstract: New uses of Cyclo-HisPro (CHP) or a salt thereof for lowering blood pressure are disclosed. More specifically, the present invention relates to a pharmaceutical composition for lowering blood pressure, containing CHP or a salt thereof, and a functional health food composition containing CHP or a salt thereof; a method for lowering blood pressure using CHP or a salt thereof; a use of CHP or a salt thereof in the manufacture of antihypertensive agents; a pharmaceutical composition or a functional health food, for preventing or treating hypertension or complications thereof, containing CHP or a salt thereof; a method for preventing or treating hypertension or complications thereof by using CHP or a salt thereof; and a use of CHP or a salt thereof in the manufacture of a medicament for preventing or treating hypertension or complications thereof.

Abstract: The present invention relates to a pharmaceutical composition and the like for lowering blood cholesterol, preventing or treating cardiovascular diseases and reducing inflammation, containing, as an active ingredient, an inhibitor of binding between CAP1 and PCSK9, an inhibitor of binding between CAP1 and resistin, or a CAP1 gene expression inhibitor. The present invention can lower the level of blood LDL-cholesterol by inhibiting the binding of CAP1 and PCSK9, the binding of CAP1 and resistin or the expression of a CAP1 gene. Therefore, the present invention can be effectively used as a pharmaceutical composition and the like for treating abnormal blood cholesterol levels and various cardiovascular diseases caused thereby, such as dyslipidemia, stroke, arteriosclerosis, and the like, and for inhibiting inflammation.

Abstract: A sinus entering endoscope according to an embodiment of the present invention comprises: a body including a plurality of operation parts; an insertion part extending from the front end of the body to be inserted into the sinus through the nasal cavity, and having at least one working channel; and an applicator load part which is disposed in the body and on which a plurality of applicators which can selectively enter through the working channel can be mounted.

Abstract: A system for monitoring a volume of a bladder during a surgical procedure. The system includes one or more processors; and a memory that is communicatively coupled to the one or more processors and stores one or more sequences of instructions, which when executed by one or more processors causes steps to be performed comprising: receiving information of a maximum volume of the bladder before the surgical procedure; receiving one or more ultrasound images from an ultrasonic scanner; based on the one or more ultrasound images, determining a volume of the bladder; comparing a maximum volume of the bladder to the determined volume of the bladder; and responsive to a difference between the maximum volume and determine volume of the bladder exceeding a threshold, issuing a warning associated with the difference.

Abstract: An apparatus for imaging examination of cells on a surface of living tissue using moxifloxacin includes: a light source emitting light towards living tissue stained with moxifloxacin; a photographing unit photographing the living tissue subjected to fluorescence excitation by the light emitted from the light source; a lens unit controlling the light emitted from the light source or a fluorescence path of moxifloxacin excited by the light; an objective lens controlling a focus of the photographing unit; an active lens disposed between the objective lens and the photographing unit and changing a focal position on the living tissue; and an image generator performing image processing of a cell image of the living tissue photographed by the photographing unit to generate an in-focus image, in which the entirety of the cell image is in focus.

Abstract: There is provided a method of providing information about prognosis after cardiac arrest. The method includes the steps of: calculating biological information based on a signal relating to a hemoglobin concentration measured from a cerebral region of a subject to be measured; and providing the information about the prognosis after cardiac arrest of the subject with reference to the calculated biological information and a biomarker relating to the prognosis after cardiac arrest measured from a blood of the subject.

Abstract: The present disclosure relates to a novel compound or a salt thereof, a composition for detecting cysteine, a fluorescent probe, and a composition for diagnosing cancer, which contain the same, a method for detecting cysteine, a method for providing information for diagnosing cancer, and a method for producing the novel compound. According to the present disclosure, there may be provided a method of synthesizing and purifying a fluorescent probe for cysteine detection and applying the same to diagnose cervical cancer by detecting cysteine in human urine.