Abstract: The invention provides a method of determining an HCC subtype in a subject comprising a) obtaining a sample from the subject, b) assaying the sample to detect the expression of 1 or more biomarkers, and c) correlating the expression of the biomarkers with an HCC subtype in a subject. The invention further provides methods of detecting HCC stem cells in a sample. Additionally, the invention provides methods and compositions for treating subjects with HCC that take advantage of the biomarkers associated with HCC stem cells.

Abstract: Bike comprising a first frame element extending from one end carrying a front wheel housing to a lower end, a second frame element extending to a lower end rigidly fixed to the first lower end, a rear fork comprising a chainstay extending from the first element to a spindle support and a seat stay extending from the spindle support to the second element, a crankset having a lateral chainring, a rear wheel driven by a sprocket inside the fork, a belt engaged with the chainring and the sprocket. The chainstay has a major portion arranged below a straight line passing through the lower ends of the chainring and of the sprocket. The belt extends through the triangle formed by the second frame element, the chainstay and the seat stay, which form an irremovable assembly.

Abstract: The present invention provides a system and method for a set of Extensible Authentication Protocols (EAPs) that can serve Confidentiality, Authentication, Authorization and Accounting (CAAA) issues at an affordable cost. According to one embodiment of the invention, a system and method is provided to generate random sequences (through prime numbers) which can be used in the authentication process of certificateless extensible authentication protocols (EAPs) for mobile and wireless communications. The invention also provides a light weight security with better performance in comparison to the lower layer chip level security provided by 2G, 3G or 4G applications.

Abstract: Methods for synthesis and manufacture of polysaccharide-protein conjugate vaccines at high yield are provided. The methods involve reaction of a hydrazide group on one reactant with an aldehyde or cyanate ester group on the other reactant. The reaction proceeds rapidly with a high conjugation efficiency, such that a simplified purification process can be employed to separate the conjugate product from the unconjugated protein and polysaccharide and other small molecule by-products.

Abstract: A testing device is provided that may be attachable and detachable from a smoke detector. The testing device may have a rod that pushes a testing button on the smoke detector. The testing device may have a light detector which will actuate the rod to push the testing button if the light from an appropriate remote control or other light source is directed onto it, in order to verify that the smoke detector is operating properly without manually pushing the testing button. The testing device may store a unique identifier (ID) and generate and transmit data pertaining to results of the testing of the smoke detector.

Abstract: The invention concerns a method of controlling an electronic device (5) using a wireless mobile device (1) having a display (3), and video capturing unit (4), the method comprising successive steps of: establishing a video call between said mobile device and a remote server (6) such that said remote server receives video images captured by said mobile device; performing image recognition to identify an electronic device in said captured video; detecting motion of said video capturing unit; and transmitting a control signal to said electronic device based on the motion of the video capturing unit.

Abstract: This disclosure provides a method of inducing epithelial cell growth. The method includes administering an effective amount of a K-type CpG oligonucleotide, thereby inducing epithelial cell growth. The epithelial cell can be in vivo or in vitro. Methods are also provided for inducing wound healing in a subject. The methods include administering to the subject a therapeutically effective amount of at least one K-type CpG ODN.

Abstract: A reporting and analyzing mortgage information system and method include receiving portfolio information from a lender, presenting the lender with predictive modeling and recapture metrics. The system provides for the dynamic definition of data sets and report sets using the received portfolio information and industry-wide recapture metrics. The recapture metrics are derived by matching loan payoff and new loan origination activity.

Abstract: A teaching and learning method and system (143, 145, 147, 148, 152) communicates exercises, including URL's of Web pages and questions related thereto. Each exercise is distributed by the teacher's computer (143), synchronously, or downloaded by a student computer (147), asynchronously. An indicator (129) used on the Web page of one computer can be viewed on the same Web page displayed on the other computers. Responses are processed by the response server (145) and by comparison and evaluation logic, and displayed contemporaneously on the teacher's computer, together with scoring information (105, 106) and with URL's (107) associated with links used on each student computer. Scores are awarded automatically, or arbitrarily by clicking on the screen (105) of the teacher's computer. A feedback signal (80) may appear on the student computer with each keystroke to indicate its correctness. Responses selected on the teacher's computer may viewed on the student computers or on a Class Display (171).

Abstract: Surface controlled subsurface control valves for use in wells and methods of controlling the same. In one embodiment, a valve includes a valve body, a bore closure assembly, a mechanical linkage, a drive assembly, and a control assembly. The valve body defines a bore for fluid to flow through when the bore closure assembly is in an open position. When the bore closure assembly is in its closed position, the bore closure assembly prevents fluid from flowing through the bore. The mechanical linkage is operatively connected to the bore closure assembly and to the drive assembly. The primary control assembly determines a force to apply to the mechanical linkage based on a present operating condition of the valve and causes the drive assembly to apply the determined force to the mechanical linkage. As a result, the mechanical linkage drives the bore closure assembly.

Abstract: The invention provides chimeric antigen receptors (CARs) comprising an antigen binding domain of a KDR-1121 or DC101 antibody, an extracellular hinge domain, a T cell receptor transmembrane domain, and an intracellular domain T cell receptor signaling domain. Nucleic acids, recombinant expression vectors, host cells, populations of cells, antibodies, or antigen binding portions thereof, and pharmaceutical compositions relating to the CARs are disclosed. Methods of detecting the presence of cancer in a host and methods of treating or preventing cancer in a host are also disclosed.

Abstract: A patient support apparatus includes a bed frame having a head end and a foot end and control circuitry carried by the bed frame. The control circuitry receives information about conditions of the patient support apparatus. A light is coupled to the bed frame adjacent the foot end and is coupled to the control circuitry. The light is in a first state when the patient support apparatus is operating normally and the light is in a second state when the control circuitry detects an alert condition.

Abstract: A method for calculating risk associated with low cholesterol includes providing a computer processor and assigning a point value to each of a plurality of parameters associated with an applicant. The method also includes calculating, using the computer processor, a total point value by summing the point value for each of the plurality of parameters and determining, using the computer processor, a risk category associated with low cholesterol using the total point value.

Abstract: Particles of a flow of aerosol are collected and analyzed by passing them through a housing having an inlet area, an outlet area, and a collection and analysis area interconnecting the inlet and outlet areas. A collection electrode has a tip disposed in the collection and analysis area and particles are collected thereon. After collection, the particles are ablated and atomic emissions are collected for analysis of the particles.

Abstract: A method of cementing in a subterranean formation comprising the steps of: (A) introducing a cement composition into the subterranean formation, the cement composition comprising: (i) cement; (ii) water; and (iii) a high-density additive selected from the group consisting of silicon carbide, sintered bauxite, and any combination thereof, wherein the cement composition has a density of at least 16 pounds per gallon; and (B) allowing the cement composition to set. According to an embodiment, the high-density additive is in a concentration of at least 30% by weight of the cement. A cement composition for use in an oil or gas well comprises: (A) cement; (B) water; and (C) a high-density additive selected from the group consisting of silicon carbide, sintered bauxite, and a combination thereof, wherein the high-density additive is in a concentration of at least 30% by weight of the cement, and wherein the cement composition has a density of at least 16 pounds per gallon.

Abstract: A brush seal assembly for sealing a journal assembly includes a base flange configured and adapted to be mounted to a journal head, e.g., in a vertical pulverizer. A cylindrical skirt is mounted to the base flange and extends in an axial direction from the base flange. A seal mounting ring is mounted to the skirt opposite the base flange, and an annular brush seal is mounted to the seal mounting ring. The brush seal is configured and adapted to seal between the skirt and a journal housing.

Abstract: An architectural system adaptable to patient acuity level has a headwall unit with a cavity, a ceiling unit, and a column coupled to the ceiling unit. The column is movable between a first position in which at least a majority of the column is situated in the cavity and a second position in which the column is situated outside the cavity. Various types of patient-care equipment is also disclosed. The patient-care equipment is included in, or is coupleable to, one or more of the ceiling unit, the headwall unit, or the column.

Abstract: A cementing fluid may include an aqueous fluid, a hydraulic cement, and a cement suspending agent comprising a crosslinked particulate, wherein the crosslinked particulate is made from a reaction comprising: a first monofunctional monomer, a primary crosslinker, and a secondary crosslinker. In some instances, the reaction may further comprise a second monofunctional monomer.

Abstract: Techniques and devices based on antenna structures with a MTM loading element.