Abstract: A system and method for authentication a user attempting access to a service is disclosed herein. When a user attempts to gain access, a client associated with the user generates a unique authentication code that is stored at a callback server associated with the client. The user accesses an authentication server associated with the service and provides the authentication server with standard login credentials. The authentication server also obtains the authentication code from the user. If the authentication server successfully verifies the user's credentials, then the authentication server transmits a code validation request to the callback server to validate the authentication code. The callback server verifies that the received code matches a stored code and is current, and then issues a reply message to the authentication server. The authentication server grants or denies the user's access request based on the reply.

Abstract: Immunotherapies, particularly chimeric antigen receptors targeting IL-13R?2 and their use for treating cancer are provided. A single chain fragment variable (scFv) that specifically binds IL-13R?2, chimeric antigen receptors (CARs) including the IL-13R?2 scFv, nucleic acids encoding the CARs, vectors including the nucleic acids encoding the CARs, and immune cells expressing the CARs are provided. Also provided are methods of treating a subject with cancer, including administering to the subject an immune cell expressing an IL-13R?2 scFv-CAR alone or in combination with other cancer therapies.

Abstract: Provided herein are a Heartland virus vaccine composition including a messenger ribonucleic acid (mRNA) including an open reading frame (ORF) encoding Gn or Gc of Heartland virus, a Heartland virus vaccine composition comprising a messenger ribonucleic acid (mRNA) comprising an open reading frame (ORF) encoding Gn or Gc of Heartland virus fused with human collagen type I alpha 1 (COL1A1) signal peptide, and a method of inducing immune response against Heartland virus by administering an effective amount of the Heartland virus vaccine composition to a subject in need thereof.

Abstract: A method for removing foreign matter from an agricultural product stream of a manufacturing process. The method includes conveying a product stream past an inspection station; scanning a region of the agricultural product stream as it passes the inspection station using at least one light source of a single or different wavelengths; generating hyperspectral images from the scanned region; determining a spectral fingerprint for the agricultural product stream from the hyperspectral images; comparing the spectral fingerprint obtained in step (c) to a spectral fingerprint database containing a plurality of fingerprints using a computer processor to determine whether foreign matter is present and, if present, generating a signal in response thereto; and removing a portion of the conveyed product stream in response to the signal. A system for detecting foreign matter within an agricultural product stream is also provided.

Abstract: Methods and systems are described for novel uses and/or improvements to federated learning. As one example, methods and systems are described for improving the applicability of federated learning across various applications and increasing the efficiency of training a global model through federated learning. As another example, methods and systems are described for ensuring comprehensive training data is available to models assigned by the federated learning server. Additionally, methods and systems are described for improving the rate of training a global model through federated learning.

Abstract: A method for determining potentially undesirable voices, in embodiments, includes: receiving audio recordings comprising voices associated with undesirable activity, and determining audio components of each of the audio recordings. The method may further comprise generating a multi-dimensional vector of the audio components for each of the plurality of audio recordings, and comparing audio components between the multi-dimensional vectors to determine clusters of multi-dimensional vectors, each cluster comprising two or more of the multi-dimensional vectors of audio components, wherein each cluster corresponds to a blacklisted voice. The method may further comprise receiving an audio recording or audio stream, and determining whether the audio recording or audio stream is associated with a voice associated with undesirable activity based on a comparison to the clusters.

Abstract: Embodiments herein provide a system for electrically heated gas mixture mediated industrial plant processes providing a fossil fuel free approach. The system utilizes a gas mixture as heating medium that directly transfers heat to a raw material required for processing the raw material into an end product. The gas mixture used as a heating medium can be a byproduct generated during processing or a combination of stable gases that are reutilized and recirculated to carry heat and dissipate the heat at various stages of processing in accordance with a heating medium design loop. The heating medium design loop disclosed is designed such that it eliminates the need of heat management equipment like a Thermal Energy Storage (TES) system used by existing approaches. Entire heating of the plant is carried out using electric gas heaters heated using renewable electric sources to provide the fossil fuel free design.

Abstract: Methods and systems are described here for porting accounts to multiple computing platforms. Blockchain technology may be used and in particular cryptographic tokens (e.g., non-fungible tokens) may be used. A cryptographic token may represent a user account and may enable usage of the cryptographic token to provide portability of the user account. An access control system may be used to perform operations described herein. The access control system may receive a request for using, at a computing platform, an account of the user. The request may include an identifier of a cryptographic token. The access control system may determine, based on the cryptographic token, that access to the user account may be permitted and the request may be fulfilled.

Abstract: A variety of methods are disclosed, including, in one embodiment, a method comprising: applying a wettability modifier coating on a surface of a downhole tool; disposing the downhole tool into a wellbore extending into a subterranean formation, wherein the wettability modifier coating is disposed on the surface of the downhole tool; traversing the wellbore with the downhole tool; and removing the downhole tool from the wellbore.

Abstract: Kits and methods to distinguish between false and true labor are provided. The kits and methods can utilize differences in abundance and/or differences in the rate of change in abundance of B7-H2, SORC2, TF, C1-Esterase Inhibitor, Ran, IMDH1 and/or PGAM1, as markers of true labor.

Abstract: This document provides methods and systems for stabilizing nicotine and incorporating nicotine into one or more oral products. This document also provides oral products. Nicotine can be stabilized by mixing liquid nicotine with cellulosic fiber such that the liquid nicotine absorbs into pores of the cellulosic fiber to form a cellulosic fiber-nicotine mixture. In some cases, a cellulosic fiber-nicotine mixture can be combined with one or more binders and molded into an oral product.

Abstract: A cartridge of an electronic vaping device includes a housing assembly and a reservoir cap assembly. The housing assembly is a single piece housing assembly. The reservoir cap assembly includes a reservoir cap having a hole there through and at least one wick extending through an opening in the reservoir cap.

Abstract: Methods and systems are described for novel uses and/or improvements to federated learning. As one example, methods and systems are described for improving the applicability of federated learning across various applications and increasing the efficiency of training a global model through federated learning. As another example, methods and systems are described for ensuring comprehensive training data is available to models assigned by the federated learning server. Additionally, methods and systems are described for improving the rate of training a global model through federated learning.

Abstract: Methods of treating a subject with diabetes or Alzheimer's disease with a disclosed insulin isoform or C? polypeptide are provided. Methods of detecting insulin isoforms or C? polypeptides are also provided.

Abstract: Aspects of the subject technology relate to systems and methods for packing nuclear magnetic resonance (“NMR”) antennas for an NMR sensor. Specifically, a magnetic shielding layer of the NMR sensor can be formed in a first concentric layer about a mandrel of a downhole tool. A first antenna of a plurality of antennas of the NMR sensor can be formed in a second concentric layer on top of the first concentric layer through an automated machining process. Further, a second antenna of the plurality of the antennas of the NMR sensor can be formed in a third concentric layer on top of the second concentric layer through the automated machining process.

Abstract: Provided are antigen-binding molecules capable of binding to IL-11, and methods of medical treatment and prophylaxis using the same.

Abstract: Disclosed are methods, systems, and non-transitory computer-readable medium for testing and applying codes to electronic shopping carts. For instance, the method may include monitoring a shopping cart associated with an e-commerce website and with a user; in response to detecting a change to the shopping cart, testing codes with respect to a present content of the shopping cart to determine valid codes; selecting at least one of the valid codes; determining a status of the session; and performing an action based on the status and the at least one selected code. The testing the codes with respect to the present content of the shopping cart may include: cloning the shopping cart to form a cloned shopping cart in a shadow session; and/or obtaining the codes; and testing the codes on the cloned shopping cart in the shadow session to determine the valid codes.

Abstract: Leucine zipper-bearing kinase (LZK) targeted degraders are disclosed. The compounds have a general formula Q-L-Z where Q is an LZK binding moiety, L is a linker, and Z is an E3-ligase binding moiety. The compounds inhibit LZK activity and/or degrade LZK. The compounds may be used to treat diseases or conditions characterized at least in part by LZK overexpression.

Abstract: At least one example embodiment relates to a chewing gum. In at least one example embodiment, the chewing gum comprises a gum base polymer and oil. The gum base polymer includes polyvinyl acetate (PVA) in an amount ranging from 35 weight percent to 55 weight percent of the chewing gum. The oil is present in an amount greater than 8 weight percent of the chewing gum. The oil includes a triglyceride, triacetin, and nicotine or a nicotine derivative. The triglyceride is present in an amount greater than or equal to 5 weight percent of the chewing gum. At least one example embodiment relates to a method of preparing a controlled-release nicotine chewing gum.

Abstract: This disclosure relates generally to methods and systems for handling autoimmune disorders. Effective handling techniques for treating the autoimmune disorders are limited. The present disclosure herein solves the problem of treating and handling the autoimmune disorders effectively by identifying the microbial epitopes present in the sample of the subject and by mapping the identified epitopes through the epitope knowledgebase. In the present disclosure, a biological sample is collected from a subject. Next, one or more DNA sequences are extracted, and microbial taxa and one or more pathogenic microbes are identified. Further, one or more microbial epitopes from the biological sample are identified. the autoimmune disorders of the subject are then assessed, based on at least one of (i) the one or more pathogenic microbes and (ii) the one or more microbial epitopes, using the epitope knowledgebase, to generate an artificial sequence construct, using one or more mimic epitopes.