Abstract: A digitally controlled lens system is disclosed. In some embodiments, the lens system includes a controller and an electro-optic lens electrically connected to the controller. The electro-optic lens includes a first substantially transparent substrate; a first electrode layer disposed on the first substantially transparent substrate, the first electrode layer including a plurality of electrodes; a second substantially transparent substrate; a second electrode layer disposed on the second substantially transparent substrate; and a liquid crystal layer located between the first electrode layer and the second electrode layer. The controller is configured to generate a refractive index pattern of liquid crystal layer by controlling voltage applied on the first electrode layer and the second electrode layer.

Abstract: Provided herein are compositions and methods for the viral gene therapy (e.g.

Abstract: A fracture plug having V-shaped recessions in a housing and complementary wedges is disclosed. The V-shaped recessions are broader at a top of the fracture plug and narrower toward the bottom and the wedges are complementary to the V-shaped recessions. The wedges have a similar thickness and radius as the housing and the wedges sit within an envelope defined by an exterior and interior radius of the housing.

Abstract: A method is disclosed, comprising: accessing a plurality of transactions including a first and a second entity; sorting the plurality of transactions into a plurality of transaction series; splitting each transaction series into a first subset of transactions and a corresponding second subset of transactions; analyzing transactions in each first subset of transactions to determine a recurrence period; based on the determined recurrence period, predicting one or more transaction dates of transactions in the corresponding second subset of each first subset of transactions; and generating a target label for each first subset of transactions based on an outcome of the prediction of the one or more transaction dates. The first entity may be a customer of a plurality of customers and the second entity may be a merchant of a plurality of merchants. Each transaction series may comprise transactions between the first entity and the second entity.

Abstract: A blend including 50% to 95% reinforcing particles by weight, and 5% to 50% filler particles by weight, of the blend, wherein the reinforcing particles have mean particle size within 70% or less of the mean particle size of the filler particles is disclosed. Such blends can be used to prepare metal matrix composites that can be infiltrated with a binder to form harden composites that can be used for the manufacture of tools.

Abstract: An electronic smoking article includes an outer housing extending in the longitudinal direction, a liquid aerosol formulation, a heater operable to at least partially volatilize at least a portion of the liquid aerosol formulation and form an aerosol, a power supply operable to apply voltage across the heater, at least one light emitting diode, a charging button assembly including a conductive post operable to form a first external, electrical contact at the upstream end of the electronic smoking article, and a second external, electrical contact including a portion of an outer surface of the outer housing at the upstream end of the electronic smoking article. The first and second external, electrical contacts charge the power supply.

Abstract: A well safety valve, comprising: a first sub assembly, wherein the first sub assembly comprises: an outer housing having a central bore extending axially through the outer housing, wherein the outer housing comprises an outer wall having a receptacle formed in the outer wall; a piston disposed in the receptacle; a rod, wherein the rod is disposed at an end of the piston, wherein a first magnetic sleeve is disposed around the rod; a flow tube disposed in the central bore of the outer housing, wherein the flow tube comprises a second magnetic sleeve on an exterior surface of the flow tube; and a valve member disposed in the outer housing; and one or more magnetic sensors disposed in the outer housing between the first magnetic sleeve and the second magnetic sleeve; and a second sub assembly, wherein the second sub assembly is coupled to the first sub assembly.

Abstract: A computer-implemented method for using a machine-learning trained predictive engine to predict failures, comprising receiving, from a user using a graphical user interface, electronic transaction data comprising an item and candidate transaction terms, the candidate transaction terms comprising a first transaction term, the electronic transaction data being associated with a candidate transaction. The method may determine, by a machine learning predictive engine, a likelihood of success of the candidate transaction based on the electronic transaction data, and may determine, by the machine learning predictive engine, based on the first transaction term, a second transaction term that, together with the first transaction term, increases the likelihood of success of the candidate transaction above a predetermined threshold. An indication of the second transaction term and an indication of the likelihood of success of the candidate transaction may be displayed on the graphical user interface.

Abstract: A subterranean characterization and fluid sampling device for analyzing a fluid from a subterranean formation includes a controller, a tool body, and a probing module. The tool body includes a fluid testing module configured to receive a sample of the fluid from the subterranean formation and a permanent magnet configured to induce a static magnetic field (B0). The probing module is coupled to the tool body and separate from the permanent magnet, and configured to withdraw the fluid from the formation and deliver the fluid to the testing module. The probing module comprises an antenna that generates a radio frequency magnetic field (B1) in response to a signal from the controller.

Abstract: A system that includes a vehicle system that monitors characteristics of an autonomous and/or semi-autonomous driving program. The system includes a processor that receives a first set of data from the vehicle system. The first set of data is associated with the autonomous and/or semi-autonomous driving program. The processor determines a rate premium based on the first set of data. The processor then displays a visualization that includes the rate premium on a display. The processor receives a second set of data from the vehicle system. The second set of data is associated with monitored performance of the autonomous and/or semi-autonomous driving program. The processor adjusts the rate premium based on the second set of data and displays an adjusted rate premium.

Abstract: A device receives user interface information associated with a user interface to be provided for a particular platform, and receives design information for a design of the user interface to be provided for the particular platform. The device receives a request to visually compare the user interface information and the design information, and utilizes, based on the request, a trained machine learning model to visually compare the user interface information and the design information. The device generates information, indicating defects in the user interface information, based on utilizing the trained machine learning model to visually compare the user interface information and the design information, where the defects include user interface information that does not visually match the design information. The device provides the information indicating the defects in the user interface information.

Abstract: An electronic cigarette includes a liquid supply including liquid material, a heater operable to heat the liquid material to a temperature sufficient to vaporize the liquid material and form an aerosol, a wick in communication with the liquid material and in communication with the heater such that the wick delivers the liquid material to the heater, at least one air inlet operable to deliver air to a central air passage upstream of the heater, and a mouth end insert having at least two diverging outlets. The electronic cigarette can also include an air flow diverter which directs incoming air away from a heating zone of the heater.

Abstract: Provided herein are methods for selecting a cancer patient for anti-CTLA-4 immunotherapy, or predicting whether a cancer patient will respond to anti-CTLA4 immunotherapy, based on measured levels of CXCL1 1 and/or sMICA. Such methods are useful for determining whether an anti-CTLA-4 immunotherapy is likely to improve overall survival of a cancer patient. Also provided herein are methods of treating a cancer patient with an anti-CTLA-4 immunotherapy, wherein the patient is first tested for levels of CXCL1 1 and/or sMICA. Also provided are methods for treating a cancer patient with a CXCL1 1 antagonist or sMICA ant agonist alone, or in combination with each other and/or with additional anti-cancer agents, such as a CTLA-4 antagonist.

Abstract: The present disclosure encompasses novel anti-NGF antibodies, antigen binding proteins and polynucleotides encoding the same. The disclosure further provides use of the novel antibodies, antigen binding proteins and/or nucleotide of the invention for the treatment and/or prevention of NGF related disorders, particularly in for the management of pain.

Abstract: A formation-tester tool may be positioned downhole in an openhole wellbore. The formation-tester tool may suspend proppant in fracturing fluid located in a chamber of the formation-tester tool. The formation-tester tool may generate a test fracture in an uncased wall of an area of interest of a subterranean formation adjacent to the openhole wellbore and inject the fracturing fluid and the proppant toward the uncased wall and into the test fracture. The formation-tester tool may retrieve a fluid sample from a reservoir within the area of interest of the subterranean formation by creating a drawdown pressure in the test fracture.

Abstract: Methods and systems are disclosed for managing shipped physical objects. The methods and systems comprise receiving data associated with a journey of the shipped object and determining, using a processor, alert conditions based on the received data. Alert conditions are representative of risk of damage, loss, or delay associated with the shipped object. In addition, the methods and systems comprise transmitting one or more alternative options for mitigating the alert condition to a user, receiving a selection of one of the alternative options, and modifying the journey based on the received selection.

Abstract: A method is disclosed, comprising dividing an outgoing message into a plurality of shards, and generating an error correction code corresponding to the outgoing message. The method may also include transmitting a first shard and a second shard of the plurality of shards to a core network via a radio access network (RAN). The first shard and the second shard are encrypted and the second shard is transmitted after a configurable time interval after transmitting the first shard.

Abstract: Systems and methods for erasing content stored on a set top box via a dedicated input object of a remote input device are described. A set top box (STB) receives a request to activate the set top box. The STB can create a storage location to which the STB is configured to store identifiers and passwords of a guest. The STB stores one or more user identifiers and passwords of the guest that correspond to one of one or more applications or web services accessed via the device. The STB receives, from a remote control device via a wireless communication, a command to delete the user identifiers and passwords stored on the STB responsive to selection of a delete button on the remote control device. An agent executing on the STB can delete the one or more user identifiers and passwords from the STB responsive to receipt of the command.

Abstract: Systems and methods for incorporating mandrel current measurements in deep ranging inversion. A method may include introducing a current through a transmitter into a subterranean formation, wherein the transmitter may be a component of an electromagnetic induction tool disposed in a wellbore, wherein the electromagnetic induction tool may comprise the transmitter, a toroid receiver, and a second receiver comprising a coil or electrode, wherein the transmitter, the toroid receiver, and the second receiver may be disposed on a tubular; measuring a first signal utilizing the toroid receiver, wherein the first signal may comprise a tubular current; measuring a second signal utilizing the receiver and determining at least one downhole parameter utilizing the first signal and the second signal.

Abstract: Systems and methods for censoring text characters in text-based data are provided. In some embodiments, an artificial intelligence system a be configured to receive text-based data and store the text-based data database. The artificial intelligence system may be configured to receive a list of target pattern types identifying sensitive data and receive censorship rules for the target pattern types determining target pattern types requiring censorship. The artificial intelligence system may be configured to assemble a computer-based model related to a received target pattern type in the list of target pattern types. The artificial intelligence system may be configured to use a computer-based model to identify a target data pattern corresponding to the received target pattern type within the text-based data, identify target characters within the target data pattern, and to assign an identification token to the target characters.