Abstract: The invention features compositions and methods for inhibiting the Pin1 protein, and the treatment of disorders characterized by elevated Pin1 levels.

Abstract: One embodiment of the invention is directed to a system comprising a server and a consumer device in operative communication with the server. The server comprises a processor and a computer readable medium coupled to the processor. The computer readable medium comprises computer readable program code embodied therein. The computer readable program code is adapted to be executed by the processor to receive an authorization request message for a transaction conducted by a consumer with a merchant, send the authorization request message to an issuer, modify an authorization response message to include receipt preference data, and send the authorization response message comprising the receipt data to the merchant, wherein the merchant generates a receipt for the consumer according to the receipt preference data.

Abstract: Exemplary embodiments relate to the secure storage of security questions through an immutable log, such as a blockchain. The security questions may be stored in a centralized location, accessible from an application or browser tab running on the user's device. When a security question is required, such as to perform a password reset on a website, the website may interact with the application or browser tab, which retrieves the question(s) from the blockchain. The user may enter their answers to the question(s), which may be hashed by the application or tab. The hashed answers may be entered into the original requesting website, which may verify with the blockchain that the correct answers have been provided. Thus, the requesting website sees neither the questions nor the answers. Additional security features may include logging requests for questions, so that a user can determine if a security question may have been compromised.

Abstract: A method may comprise plotting treatment data to form a plot of the treatment data, fitting a function to the plot of the treatment data, determining an intercept of the function, calculating one or more coefficients, plotting the one or more coefficients on a histogram, and identifying one or more active flowpath elements on the histogram. A system may comprise a fluid handling system and an information handling system. The fluid handling system may comprise a fluid supply vessel, wherein the fluid supply vessel is disposed on a surface; pumping equipment, wherein the pumping equipment it attached to the fluid supply vessel and disposed on the surface; wellbore supply conduit, wherein the wellbore supply conduit is attached to the pumping equipment and disposed in a formation; and a plurality of flowpath elements, wherein the flowpath elements fluidly couple the wellbore supply conduit to the formation.

Abstract: The invention provides a method for identifying existing groups, an electronic device and a group device. The method includes: broadcasting a request signal in response to determining that a group identification function of the electronic device has been started, wherein the request signal is configured to trigger a first group device to display a first group pattern, and the first group pattern corresponds to a first group which the first group device belongs to; detecting a first identification signal from the first group device, wherein the first identification signal indicates the first group pattern of the first group; and displaying a first group option corresponding to the first group, wherein the first group option indicates the first group pattern.

Abstract: Disclosed are examples of systems, methods and techniques related to delivering a service widget that collects data and provides a service. A service widget is provided in response to a widget delivery request received from a user browser. The delivered service widget enables the user browser to request item-related services from an enterprise. A request for the item-related services is received by an enterprise from the delivered service widget. Provision of the service is enabled upon confirmation that an authentication token fetched from the client backend system is valid for the client backend system, the services request may be delivered to an enterprise server. The enterprise, in response to an analysis of the information related to the item available for purchase, may indicate that the item available for purchase meets a purchase threshold of the enterprise and provide an evaluation result including parameters of the item-related services.

Abstract: Some embodiments of the present disclosure are directed to methods and compositions for the treatment of tumors, using a combination of immunotherapeutic agents and tumor-targeting viral capsid protein assemblages comprising anti-cancer molecules conjugated to viral capsid proteins.

Abstract: Example embodiments relate to a method of protecting a surface of an e-vaping device portion from corrosion, the method including preparing a coating mixture configured to protect the surface from corrosion, and coating the surface with a protective coating based on the coating mixture, wherein the coating is performed via one of electrodeposition, dipping, spraying, and vapor deposition, and the coating mixture includes at least one of a silane and a resin.

Abstract: Various embodiments are generally directed to a dynamic, flexible acronym decoder. A user may submit a query via one of a plurality of user interfaces. Information describing the user may be received to generate a context vector for the user. The query may be processed against a database of terms using the context vector, a machine learning model, and content tags applied to terms in the database. Processing the queries against the database may return a result set, and the ML model may be used to compute a score for each result. The results may be ordered based on the scores and returned as responsive to the query.

Abstract: Object manipulation in warehouses and logistics facilities is a challenging task because of the unstructured environment. The unstructured environment can have items/objects with different form factors, weight, shape, and size. Traditionally, multiple robots have been used to handle for specific task to be performed by an individual robot which requires high floor. This leads to higher cost and infrastructure. Embodiments of the present disclosure provide a gripper apparatus that addresses a single gripper design handling multiple parcels, wherein the apparatus consists of cm? fingers parallel to each other and can be independently controlled through actuators, each finger has a force sensors feedback and also actuators which are controlled with force. Each finger comprises a linear slider for actuation for gripping objects and wherein bottom fingers are moved to provide enough gravity support.

Abstract: A controller may identify a problematic path from several paths over which to route egress traffic from a site, may determine a threshold amount of traffic to shift from the problematic path, and may implement different potential traffic shifts for shifting similar amounts of traffic as the threshold amount. The controller may provide the labels or header values that different nodes in the site may place in the egress traffic in order to control which path is used to distributed that egress traffic. The controller may modify routing policies affecting different Autonomous System numbers, address prefixes, or other routing parameters to select and/or shift egress traffic, that is associated with those routing parameters and that is about equal to the threshold amount of traffic, from the problematic path to a different path.

Abstract: A method and system for accurately calculating and implementing optimized airplane flight trajectories in the operational environment that requires the involvement and cooperation of various stakeholders that provide data from different agencies that are often physically located in different geographical locations, and executing the optimized trajectories in the operational environment.

Abstract: Systems and methods for securely pairing a transmitting device with a receiving device are described. The systems and methods may communicate with a first device via a first communication method over a wireless communication network. The systems and methods may transmit, to the first device via a second communication method, a first sensory pattern representing a first key. In addition, the system and methods may communicate with the first device via the first communication method using the first key.

Abstract: A method for training a subject diagnosed with a stress disorder caused by a trauma, including: selecting a challenge expected to trigger a symptom of the stress disorder in the subject; exposing the subject to the challenge; recording electrical signals generated by the brain of the subject by at least one electrode, in conjunction with the exposing; processing the recorded electrical signals to estimate an activation level of at least one specific brain region; presenting at least one indication of the estimated activation level to the subject; repeating the recording, the processing and the presenting.

Abstract: A processor implemented method of determining personalized wellness measures associated plurality of dimensions of an individual is provided. The processor implemented method includes at least one of: receiving, plurality of information associated with plurality of sensors; processing, the plurality of information associated with the plurality of sensors to obtain plurality of low-level features; determining, at least one digital behavioral marker based on the plurality of low-level features; processing, at least one dimension associated with a plurality of well-being of the individual based on the at least one digital behavioral marker to determine a set of objective features; generating, one or more wellness scores for the set of objective features associated with the at least one well-being dimension of the individual; and dynamically recommending, one or more behavior changes based on the one or more generated wellness scores of the individual.

Abstract: A control line pinching mechanism can include a pinching sleeve, a clamping sleeve, a tubing, a control line, and a pinching block. The clamping sleeve can have a slot. A control line can extend between the tubing and the slot of the clamping sleeve. A pinching block can be disposed within the slot of the clamping sleeve. The pinching sleeve can be movable relative to the slot from a released position to a pinching position in which the pinching sleeve contacts and radially compresses the pinching block against the control line to pinch the control line against the tubing.

Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.

Abstract: A method for automatic redemption of available reward points is disclosed. The method may include linking a stored data profile of a customer of a merchant with at least one reward account of the customer, and receiving an update corresponding to a changed value of reward points available for redemption. The method may include updating the stored data profile of the customer with the changed value of reward points for redemption, and automatically accessing a list associated with the profile of the customer in response to the updating the stored data profile of the customer. The list may include at least one item to be purchased. The method may include identifying and purchasing at least one item from a subset of items from the list whose redemption values are equal to or less than the changed value of reward points based on a customer preference setting.

Abstract: A method of treating in a subterranean formation including combining a demulsifier; proppant; an emulsifier; an oil base fluid; and aqueous base fluid to form an oil-external emulsified fluid; and introducing the oil-external emulsified fluid into the subterranean formation. A method of forming a wellbore fluid including combining proppant; a demulsifier; an aqueous base fluid, an oil base fluid, and an emulsifier to form a pre-emulsified fluid; and mixing the pre-emulsified fluid to form an oil-external emulsified fluid.