Patents Assigned to SHANGHAI UNIVERSITY
  • Patent number: 11752819
    Abstract: A wheel-legged amphibious mobile robot with a variable attack angle, which belongs to the technical field of robot structure technology. The robot includes three parts: motion unit, body trunk and power unit. As a key structure, the motion unit mainly includes a moving mechanism, a wheel assembly, a telescopic mechanism and a transmission device. The robot drives the telescopic mechanism to reciprocate linearly through a gear and rack set, and pushes “legs” to expand and retract, so as to realize a mutual switching between a wheeled mode and a gait mode. Under transmission of bevel gear set, the blades can rotate at any same angle at the same time, to change the attack angle and realize the steering. The robot provided by the present disclosure can effectively adapt to a complex and harsh amphibious environment, and meet a series of operation requirements such as rapid movement, obstacle climbing, underwater steering.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: September 12, 2023
    Assignee: SHANGHAI UNIVERSITY
    Inventors: Yi Sun, Longteng Zhang, Huayan Pu, Min Wang, Yan Peng, Jiheng Ding, Jun Luo, Shaorong Xie
  • Publication number: 20230277699
    Abstract: A tumor stroma imaging agent with a chemical structural formula (I): is provided, where R is hydrogen or fluorine. Compared with the prior art, the tumor stroma imaging agent exhibits significant affinity for fibroblast activation protein (FAP), high uptake for a malignant tumor with high FAP expression in a tumor stroma, and high sensitivity and specificity for the diagnosis of a malignant tumor, and is not prone to false positives. Therefore, the tumor stroma imaging agent can be effectively and safely used for the diagnosis and treatment of various malignant tumors with a prolonged half-life and an extended window period, which is conducive to clinical application.
    Type: Application
    Filed: October 13, 2020
    Publication date: September 7, 2023
    Applicant: SHANGHAI UNIVERSITY OF MEDICINE&HEALTH SCIENCES
    Inventors: Gang HUANG, Bin LI
  • Patent number: 11726108
    Abstract: The present disclosure relates to a signal conditioning system for improving low-frequency measurement performance of an acceleration sensor. The signal conditioning system includes: a charge integration circuit, a high-pass filter circuit, a lead-lag network, an anti-aliasing filter circuit, and a gain adjustment circuit. An input terminal of the charge integration circuit is connected to the acceleration sensor, an output terminal of the charge integration circuit is connected to an input terminal of the high-pass filter circuit, an output terminal of the high-pass filter circuit is connected to an input terminal of the lead-lag network, an output terminal of the lead-lag network is connected to an input terminal of the anti-aliasing filter circuit, and an output terminal of the anti-aliasing filter circuit is connected to an input terminal of the gain adjustment circuit.
    Type: Grant
    Filed: August 27, 2021
    Date of Patent: August 15, 2023
    Assignee: Shanghai University
    Inventors: Huayan Pu, Peng Jiang, Jiheng Ding, Yi Sun, Min Wang, Yan Peng, Jun Luo, Shaorong Xie
  • Patent number: 11714010
    Abstract: A reactor temperature measurement system includes a Fiber Bragg Grating sensor array arranged in a body of the reactor for monitoring temperatures at multiple positions in an axial direction of the body to obtain temperature sensing optical signals; and a fiber grating demodulator, connected to the Fiber Bragg Grating sensor array, and used to demodulate the temperature sensing optical signals. A method for preparing a Fiber Bragg Grating includes preparing a Fiber Bragg Grating by using a single-mode fiber and annealing the Fiber Bragg Grating, which includes heating the Fiber Bragg Grating to a temperature above 400° C. and maintaining for 100 to 200 hours.
    Type: Grant
    Filed: January 8, 2021
    Date of Patent: August 1, 2023
    Assignees: Shanghai Huayi New Material Co., Ltd., Shanghai University
    Inventors: Yunqi Liu, Xiaolong Si, Linfang Wu, Chengbo Mou, Yan Zhuang
  • Patent number: 11692607
    Abstract: A magnetic suspension type sensing system for space full-degree-of-freedom absolute poses is provided. The system includes a reference platform, multiple quasi-zero stiffness supporting legs and a platform to be tested. The reference platform and the platform to be tested are connected in a spherical hinge mode through the multiple quasi-zero stiffness supporting legs. Each of the multiple quasi-zero stiffness supporting legs includes a lower end spherical hinge, a lower end cover, a positive stiffness unit, a negative stiffness unit, a shaft, a lower end shell, an upper end shell and an upper end spherical hinge.
    Type: Grant
    Filed: November 26, 2021
    Date of Patent: July 4, 2023
    Assignees: Chongqing University, SHANGHAI UNIVERSITY
    Inventors: Huayan Pu, Yan Jing, Jinglei Zhao, Jun Luo, Yi Qin, Zhijiang Xie, Jie Ma
  • Patent number: 11686666
    Abstract: The present invention discloses a method for detecting a microstructure of a functionally graded material based on digital acousto-optic holography, including the following steps: excite a sample with an ultrasonic wave; record a light wave; form a single tomographic acousto-optic hologram; perform numerical reconstruction of phase information, and perform global detection. The present invention uses an acoustic-optic modulation device to modulate a laser light source of a laser of a laser device to form two light waves of different frequencies. The two light waves each constitute a Mach-Zehnder interference system to record reflection wave information and transmission wave information of an ultrasound, and are finally combined and recorded in the same hologram to form the single tomographic acousto-optic hologram.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: June 27, 2023
    Assignee: SHANGHAI UNIVERSITY
    Inventors: Wenjing Zhou, Guangcai Huang, Yingjie Yu, Shili Liu, Hongxia Shen
  • Patent number: 11660320
    Abstract: The present disclosure belongs to the technical field of biomedicine, and provides use of Faecalibacterium prausnitzii in preparation of a medicine for treating pathological ventricular remodeling and/or heart failure following myocardial infarction. The Faecalibacterium prausnitzii can improve pathological ventricular remodeling and/or heart failure caused by myocardial infarction in experimental animals, resume the systolic function, reduce the cardiac fibrosis, and inhibit the pathological myocardial hypertrophy of mice with myocardial infarction. Furthermore, the inactivated Faecalibacterium prausnitzii has no such improvement effect.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: May 30, 2023
    Assignee: Shanghai University
    Inventors: Junjie Xiao, Qiulian Zhou, Xue Pan, Danni Meng
  • Publication number: 20230160092
    Abstract: The present disclosure relates to the field of directional solidification, and in particular, to an apparatus, method, and process for directional solidification by liquid metal spraying enhanced cooling (LMSC). The process has the following beneficial effects: the apparatus of the present disclosure can regulate a solidification structure of a casting, refine a dendrite spacing, and reduce or avoid metallurgical defects, and can be used to prepare high-quality large-sized columnar/single crystal blades or other castings.
    Type: Application
    Filed: August 9, 2022
    Publication date: May 25, 2023
    Applicant: Shanghai University
    Inventors: Zhongming Ren, Jiang Wang, Xingfu Ren, Zhenqiang Zhang, Xiaoxin Zhang, Xia Li, Tingsheng Tu, Baojun Wang
  • Patent number: 11649572
    Abstract: A medicated thread manufacturing system and associated method includes first and second slideways, a thread clamping apparatus and a medicine spraying apparatus slidably arranged on the first slideway, and a thread winding apparatus slidably arranged on the second slideway. The clamping apparatus clamps two ends of a to-be-processed medicated thread, straightens the thread and twists the thread in the straightened state into a single-strand rope state. The spraying apparatus sprays a medicine towards a surface layer of the thread in the straightened state. The winding apparatus abuts a center position of the thread in the single-strand rope state, pulls and folds the thread, and rotates the thread such that the thread winds and extends from middle to two ends to be twisted in a double-strand rope state. A control apparatus is in signal connection and/or electrical connection to the clamping apparatus, the spraying apparatus and the winding apparatus.
    Type: Grant
    Filed: November 17, 2021
    Date of Patent: May 16, 2023
    Assignee: LongHua Hospital Shanghai University of Traditional Chinese Medicine
    Inventors: Liang Hongtao, Wang Chen, Yao Yibo, Tao Xiaochun, Cao Yongqing, Lu Jingen
  • Patent number: 11644479
    Abstract: A quantum-dot-based measuring system is disclosed. The quantum-dot-based measuring system includes a laser to emit excitation light, an optical fiber probe including a tail end and a tapered tip, and the tapered tip of the optical fiber probe is attached with one or more quantum dots, and the excitation light is injected from the tail end of the optical fiber probe and emitted from the tapered tip to a sample to be detected, an objective lens to collect optical signal reflected by the sample and a spectrometer to receive the optical signal.
    Type: Grant
    Filed: June 7, 2021
    Date of Patent: May 9, 2023
    Assignee: SHANGHAI UNIVERSITY
    Inventors: Na Chen, Shaoying Li, Tingyun Wang, Zhenyi Chen, Shupeng Liu
  • Publication number: 20230132468
    Abstract: Arginine deiminase (ADI)-containing genetically engineered Corynebacterium glutamicum (C. glutamicum), a fusion protein cipA-arc, use thereof, and a method for preparing [14/15N]-L-citrulline through enzymatic catalysis are provided. The ADI-containing genetically engineered Corynebacterium glutamicum (C. glutamicum) has a deposit number of CGMCC No. 19404, which expresses a fusion protein cipA-arc. Both the genetically engineered strain and the fusion protein cipA-arc can be used to convert [14/15N]-L-arginine into [14/15N]-L-citrulline.
    Type: Application
    Filed: October 13, 2020
    Publication date: May 4, 2023
    Applicant: SHANGHAI UNIVERSITY OF MEDICINE&HEALTH SCIENCES
    Inventors: Gang HUANG, Bin LI, Yue LI
  • Publication number: 20230114361
    Abstract: A laser-solid-forming manufacturing device includes a laser emitter, a magnetic field generator, and a forming platform. The laser emitter emits a laser beam which acts on a feedstock to form a molten pool. The magnetic field generator includes a spiral copper coil, a first electrode and a second electrode. The spiral copper coil is formed by spirally winding a copper tube. The first and second electrodes are arranged at respective ends of the copper tube and are used for loading a voltage to generate a magnetic field in the spiral copper coil. At any time, the spiral copper coil sleeves an action point of the laser beam and the feedstock. A corresponding laser-solid-forming manufacturing method is also presented.
    Type: Application
    Filed: December 14, 2022
    Publication date: April 13, 2023
    Applicant: Shanghai University
    Inventors: Jiang WANG, Zhongming REN, Chaoyue CHEN, Ruixin ZHAO
  • Patent number: 11596147
    Abstract: The present invention discloses an afterload device for ex situ heart perfusion, which includes an afterload energy storage module, a pressure regulation module and two flow rate regulators that are connected through a conduit. The afterload energy storage module includes a rigid closed container and a flexible container. The perfusion fluid flows into the flexible container from one side thereof through the conduit, and the perfusion fluid flows out from the flexible container at another side thereof as the flexible container is subjected to the action of the medium pressure in the rigid hermetic container. The pressure regulation module includes two pressure regulation valves and a compressible-medium source, for regulating the pressure range within the rigid hermetic container to be always maintained between the set diastolic pressure and the set systolic pressure.
    Type: Grant
    Filed: June 24, 2020
    Date of Patent: March 7, 2023
    Assignee: Shanghai University
    Inventors: Yan Peng, Zhibing Xu, Liming Xin, Jun Luo, Shaorong Xie, Huayan Pu, Shouwei Gao, Mitesh Badiwala, Yu Sun
  • Patent number: 11598315
    Abstract: A triboelectric nanogeneration module, and a combined wind turbine and a method thereof. The triboelectric nanogeneration module includes a rotating disc, and moving friction plates and fixed friction plates that are oppositely arranged outside the radial direction of the rotating disc. A nano-friction material layer is arranged on the surface of each of the moving friction plates and the fixed friction plates. Driving devices are arranged on the rotating disc in the circumferential direction at intervals. The driving devices are used for extruding the moving friction plates to move to the positions at which the moving friction plates are in contact with the fixed friction plates. The moving friction plates are connected to reset devices used for separating the moving friction plates from the fixed friction plates. The moving friction plates perform straight reciprocating movement under the action of the driving devices and the reset devices.
    Type: Grant
    Filed: May 19, 2021
    Date of Patent: March 7, 2023
    Assignee: Shanghai University
    Inventors: Yan Peng, Chuanfu Xin, Zhongjie Li, Jun Luo, Shaorong Xie, Huayan Pu
  • Publication number: 20230062689
    Abstract: A squeeze mode giant electrorheological fluid damper is disclosed. The squeeze mode giant electrorheological fluid damper comprises a support, a container and a connecting structure, wherein the support comprises a bottom plate, guide shafts and a top plate, the guide shaft is vertically fixed on the bottom plate, and the top plate is slidably arranged on the guide shaft; the container comprises a container body and two spiral spring pieces coaxially arranged in the container body, the container body is fixed on the bottom plate, the bottoms of the two spiral spring pieces are fixed to the bottom of the container, the two spiral spring pieces are not in contact with each other and are spaced by 180°; the top of the connecting structure is fixedly connected with the top plate, and the bottom of the connecting structure is fixedly connected with the tops of the two spiral spring pieces.
    Type: Application
    Filed: August 23, 2022
    Publication date: March 2, 2023
    Applicant: Shanghai University
    Inventors: Yi Sun, Ben Lu, Huayan Pu, Min Wang, Jiheng Ding, Wenchuan Jia, Yan Peng, Jun Luo
  • Patent number: 11584131
    Abstract: The present disclosure provides an inkjet assembly, an inkjet printing apparatus and an inkjet printing method for use in preparation of a display component. The inkjet assembly is for use in an inkjet printing apparatus, including a jet printing member having a first surface. A main inkjet channel, a liquid-phase channel in communication with the main inkjet channel, and a gas-phase channel in communication with the main inkjet channel are formed in the jet printing member. An axial direction of the liquid-phase channel intersects an axial direction of the main inkjet channel, and an axial direction of the gas-phase channel intersects the axial direction of the main inkjet channel. An end opening of the main inkjet channel is formed as a nozzle on the first surface.
    Type: Grant
    Filed: September 24, 2021
    Date of Patent: February 21, 2023
    Assignees: BOE TECHNOLOGY GROUP CO., LTD., Shanghai University
    Inventors: Jin Cao, Jinsong Zhang, Limin Yan, Chunming Ren, Xinguo Li, Xiao Wu
  • Patent number: 11565349
    Abstract: The present invention discloses a composite device for high-precision laser additive/subtractive manufacturing, which consists of a sealed shaping chamber, an inert protective gas source and a machine-shaping platform; wherein, the inert protective gas source is connected to the sealed shaping chamber; and the machine-shaping platform is arranged in the sealed shaping chamber, as well as there is a light path selection system is arranged right above the machine-shaping platform; in addition, there is a machining position is equipped on the machine-shaping platform, meanwhile, there are lead screws are arranged under the machine-shaping platform.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: January 31, 2023
    Assignee: SHANGHAI UNIVERSITY OF ENGINEERING SCIENCE
    Inventors: Bo He, Shuang Gao, Liang Lan, Zhijun Tan, Qi Zhang
  • Patent number: 11554414
    Abstract: A laser-solid-forming manufacturing device includes a laser emitter, a magnetic field generator, and a forming platform. The laser emitter emits a laser beam which acts on a feedstock to form a molten pool. The magnetic field generator includes a spiral copper coil, a first electrode and a second electrode. The spiral copper coil is formed by spirally winding a copper tube. The first and second electrodes are arranged at respective ends of the copper tube and are used for loading a voltage to generate a magnetic field in the spiral copper coil. At any time, the spiral copper coil sleeves an action point of the laser beam and the feedstock. A corresponding laser-solid-forming manufacturing method is also presented.
    Type: Grant
    Filed: July 2, 2020
    Date of Patent: January 17, 2023
    Assignee: SHANGHAI UNIVERSITY
    Inventors: Zhongming Ren, Jiang Wang, Jianwen Nie, Chaoyue Chen, Wei Liu, Ruixin Zhao
  • Publication number: 20220403384
    Abstract: The present disclosure belongs to the technical field of biomedicine, and provides an engineered circular RNA circmiR-29b and use thereof in preparation of a medicine for treating muscle atrophy. The present disclosure provides a circular RNA circmiR-29b including an effective sequence and a random sequence, wherein 6-13 repetitions of the effective sequence are connected in series, the random sequence is inserted between the effective sequences, and the nucleotide sequence of the effective sequence is shown in SEQ ID NO: 1. The present disclosure delivers circmiR-29b to skeletal muscle by AAV8, enabling stable expression of circmiR-29b in the skeletal muscle, thereby effectively inhibiting various types of muscle atrophy. Therefore, the present disclosure also provides a gene therapy based on the AAV8 virus vector delivering the engineered circular RNA circmiR-29b to achieve the objective of treating muscle atrophy.
    Type: Application
    Filed: October 1, 2021
    Publication date: December 22, 2022
    Applicant: Shanghai University
    Inventors: Junjie XIAO, Jin LI, Yihua BEI
  • Publication number: 20220390530
    Abstract: Disclosed are a system and a method for measuring a magnetorefractive effect of an optical fiber. The system comprises a laser, a coupler A, a sensing optical fiber, a reference optical fiber, a carrier generator, a coupler B, a photoelectric detector and a data acquisition and processing module. The coupler A, the sensing optical fiber, the reference optical fiber and the coupler B form a Mach-Zehnder optical fiber interferometer. An external magnetic field influences the refractive index of the sensing optical fiber, so that the optical path difference between two paths of optical signals in the sensing optical fiber and the reference optical fiber is changed, the intensity of an interference optical signal output by the coupler B is changed, and the refractive index change of the sensing optical fiber under the action of the magnetic field is measured by detecting and processing the interference optical intensity.
    Type: Application
    Filed: June 7, 2022
    Publication date: December 8, 2022
    Applicant: Shanghai University
    Inventors: Tingyun Wang, Yi Huang, Chuanlu Deng, Chengyong Hu