Patents Assigned to Sharp
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Publication number: 20160311819Abstract: Disclosed are the ERK inhibitors of formula (1.0) and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1.0). This invention provides compounds that are ERK inhibitors (i.e., ERK2 inhibitors). This invention also provides a pharmaceutical composition comprising an effective amount of at least one (e.g., 1) compound of formula (1.0) and a pharmaceutically acceptable carrier.Type: ApplicationFiled: December 12, 2014Publication date: October 27, 2016Applicant: Merck Sharp & Dohme Corp.Inventors: Kathryn Lipford, Danielle Falcone, David L. Sloman, David J. Witter
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Publication number: 20160311791Abstract: Novel tricyclic compounds of Formula (I) and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing osteoporosis and similar conditions. The compounds are effective as calcium sensing receptor antagonists. Pharmaceutical compositions and methods of treatment are also included.Type: ApplicationFiled: December 17, 2014Publication date: October 27, 2016Applicant: Merck Sharp & Dohme Corp.Inventors: Gui-Bai Liang, Changyou Shou, Xianghong Huo, Haisheng Wang
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Publication number: 20160311813Abstract: The invention provides certain thiazole-substituted aminoheteroaryl compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R3, R5, R6, A, Cy and the subscripts r, s, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk).Type: ApplicationFiled: December 15, 2014Publication date: October 27, 2016Applicant: Merck Sharp & Dohme Corp.Inventors: Michelle R. Machacek, Eric T. Romeo, Alan B.. Nortrup, Michael D. Altman
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Publication number: 20160316221Abstract: Since complexity is high in derivation of an enhancement merge candidate which is a scalable merge candidate, a problem may arise in that a processing amount is large when the enhancement merge candidate is used in a case where a prediction unit in which it is necessary to derive many merge candidates is small. In a merge candidate derivation section including an enhancement merge candidate section that derives a merge candidate referring to an inter-layer picture and a base merge candidate derivation section that derives a merge candidate not referring to an inter-layer picture (referring to the temporary picture or the adjacent block of the same layer), the merge candidate derived from the base merge candidate and the merge candidate derived from the enhancement merge candidate are added to a merge candidate list in a case where the size of a prediction unit is greater than a predetermined size.Type: ApplicationFiled: December 15, 2014Publication date: October 27, 2016Applicant: SHARP KABUSHIKI KAISHAInventor: Tomohiro IKAI
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Publication number: 20160311786Abstract: The present invention is directed to 2,5,6-substituted morpholine derivatives and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.Type: ApplicationFiled: December 17, 2014Publication date: October 27, 2016Applicants: MERCK SHARP & DOHME CORP., MERCK CANADA INC.Inventors: John A. McCauley, Christian Beaulieu, David Jonathan Bennett, Christopher J. Bungard, Sheldon Crane, Thomas J. Greshock, Katharine M. Holloway, Daniel McKay, Carmela Molinaro, Oscar Miguel Moradei, Satyanarayana Tummanapalli, Vouy Linh Truong, Peter D. Williams
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Publication number: 20160311820Abstract: The present invention provides Bruton's Tyrosine Kinase (Btk) inhibitor compounds according to Formula I or pharmaceutically acceptable salts thereof. Formula I or a pharmaceutically acceptable salt thereof or to pharmaceutical compositions comprising these compounds and to their use in therapy. In particular, the present invention relates to the use of Btk inhibitor compounds in the treatment of Btk mediated disorders.Type: ApplicationFiled: December 16, 2014Publication date: October 27, 2016Applicant: MERCK SHARP & DOHME CORP.Inventors: JIAN LIU, RONALD M. KIM, JOSEPH KOZLOWSKI, ARTO D. KRIKORIAN, RAJAN ANAND
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Patent number: 9478716Abstract: By using a light emitting device including an insulating substrate and a light emitting unit formed on the insulating substrate, the light emitting unit including: a plurality of linear wiring patterns disposed on the insulating substrate in parallel with one another, a plurality of light emitting elements that are mounted between the wiring patterns while being electrically connected to the wiring patterns, and a sealing member for sealing the light emitting elements, as well as a method for manufacturing thereof, it becomes possible to provide a light emitting device that achieves sufficient electrical insulation and has simple manufacturing processes so that it can be manufactured at a low cost, and a method for manufacturing the same.Type: GrantFiled: March 4, 2015Date of Patent: October 25, 2016Assignee: SHARP KABUSHIKI KAISHAInventors: Masahiro Konishi, Makoto Agatani, Toshio Hata
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Patent number: 9478766Abstract: The present invention includes forming an organic EL element on a TFT substrate, forming a sealing film on the TFT substrate so as to cover the organic EL element, performing a hydrophilic treatment on a surface of the sealing film in a frame region, forming a sealing material on a CF substrate, bonding the TFT substrate and the CF substrate together via the sealing material by placing the sealing material on a surface of the sealing film in the frame region in a vacuum, and returning the vacuum state to atmospheric pressure.Type: GrantFiled: August 22, 2013Date of Patent: October 25, 2016Assignee: SHARP KABUSHIKI KAISHAInventor: Yuki Yasuda
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Patent number: 9479682Abstract: A video signal processing device according to an embodiment of the present invention includes a motion vector detection unit and a plurality of interpolated image generation units. The motion vector detection unit detects an interpolated motion vector which represents a motion between a first broad image and a second broad image. Each of the interpolated image generation units generates an interpolated partial image corresponding to a divided area by using a first partial image of a first frame, a second partial image of a second frame, and the interpolated motion vector.Type: GrantFiled: May 14, 2012Date of Patent: October 25, 2016Assignee: SHARP KABUSHIKI KAISHAInventor: Naohiro Hohjoh
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Patent number: 9478183Abstract: In this liquid crystal display device, a potential propagation line (PVID) and video signal lines SL(1) to SL(M) are connected via coupling capacitive elements Cp(1) to Cp(M), and a capacitance drive circuit (100) causes the potential of the potential propagation line (PVID) to change in the same direction in which the potential of a video signal S(m) varies during a period of nonselection. As a result, even if there is not enough time to perform a precharge operation, the potentials of video signal lines can be similarly raised or lowered without performing a precharge operation.Type: GrantFiled: April 9, 2012Date of Patent: October 25, 2016Assignee: Sharp Kabushiki KaishaInventor: Nobuhiro Kuwabara
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Patent number: 9478012Abstract: A display apparatus includes an orientation detecting portion, a receiving portion and an image processing portion. The orientation detecting portion detects an orientation of an upper part or a lower part of a display screen of a display portion. The receiving portion receives an image signal transmitted from a source device and state information (information showing an orientation of an upper part or a lower part of the transmission image indicated by the image signal and presence/absence of black band parts). The image processing portion applies, to the transmission image, rotation processing such that the orientation of the upper part or the lower part of the display screen coincides with the orientation of the upper part or the lower part of the transmission image, scaling processing, and/or black-band processing for adding or removing black band parts, according to a detection result of the orientation detecting portion and the state information.Type: GrantFiled: July 14, 2014Date of Patent: October 25, 2016Assignee: Sharp Kabushiki KaishaInventors: Osamu Uratani, Seiji Imanishi
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Patent number: 9476579Abstract: A relay connector that is interposed between two substrates provided with mutually connectable connecting parts and that indirectly connects the two substrates, wherein the relay connector is provided with a first connecting part capable of mechanistically connecting to the connecting part of one of the substrates, and a second connecting part capable of mechanistically connecting to the connecting part of the other substrate.Type: GrantFiled: April 12, 2013Date of Patent: October 25, 2016Assignee: SHARP KABUSHIKI KAISHAInventor: Shingo Kamitani
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Patent number: 9478177Abstract: A display control circuit of a liquid crystal display device generates a double-speed progressive image signal by changing an input image signal based on interlaced scanning into a progressive scanning mode, and also by doubling the frame frequency. With the double-speed progressive image signal, a pixel value equivalent to an odd-numbered scanning line in an odd-numbered frame remains unchanged, a pixel value equivalent to an even-numbered scanning line is replaced with a black pixel value, a pixel value equivalent to an even-numbered scanning line in an even-numbered frame remains unchanged, and a pixel value equivalent to an odd-numbered scanning line is replaced with a black pixel value. An image that the double-speed interlace image signal represents is displayed on a liquid crystal panel.Type: GrantFiled: December 21, 2011Date of Patent: October 25, 2016Assignee: Sharp Kabushiki KaishaInventor: Makoto Shiomi
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Patent number: 9480052Abstract: A User Equipment (UE) for performing carrier aggregation is described. The UE includes a processor and instructions stored in memory that is in electronic communication with the processor. The UE determines an uplink control information (UCI) transmission cell in a wireless communication network with at least one frequency-division duplexing (FDD) cell and at least one time-division duplexing (TDD) cell. The UE also selects a first cell for FDD and TDD carrier aggregation. The UE further determines a set of downlink subframe associations for the first cell that indicate at least one UCI transmission uplink subframe of the UCI transmission cell. The UE additionally sends Physical Downlink Shared Channel (PDSCH) Hybrid Automatic Repeat Request Acknowledgement/Negative Acknowledgement (HARQ-ACK) information in the UCI transmission uplink subframe of the UCI transmission cell.Type: GrantFiled: July 23, 2015Date of Patent: October 25, 2016Assignee: Sharp Kabushiki KaishaInventors: Zhanping Yin, Shohei Yamada, John Michael Kowalski
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Patent number: 9478186Abstract: When an idle period is started, a voltage of the control signal is changed from a value H to a value L. As a result, the analog amplifiers provided in the signal line driver circuit are switched from the normal state to the low-driving power state. At this time, the data signal lines are set to have a constant potential. A gate voltage is changed from Vgh to Vgl at the same time as when the control signal was changed from the value H to the value L. As a result, the gate of each TFT returns to the OFF state from the ON state. The control signal remains at the value L until the idle period is over. In other words, when the next driving period is started, the voltage of the control signal is changed from the value L to the value H. As a result, the analog amplifiers in the signal line driver circuit are switched back to the normal state from the low-driving power state.Type: GrantFiled: October 21, 2011Date of Patent: October 25, 2016Assignee: SHARP KABUSHIKI KAISHAInventors: Jun Nakata, Kohji Saitoh
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Patent number: 9477124Abstract: A display device includes a display panel, a flexible circuit board, a signal transmission board, a driver component, a frame-shaped member, and a heat dissipation member. The signal transmission board is configured to transmit signals to the flexible circuit board. The driver component is mounted on the flexible circuit board and configured to process the signals from the signal transmission board and supply the processed signals to the display panel. The frame-shaped member retains the liquid crystal panel by holding edges of the display panel on a display surface side. The heat dissipation member has higher thermal conductivity than the frame-shaped member and embedded in a portion of the frame-shaped member. The heat dissipation member includes a contact portion that projects toward the signal transmission board and a distal end that is in contact with a portion of the flexible circuit board on which the driver component is mounted.Type: GrantFiled: September 2, 2013Date of Patent: October 25, 2016Assignee: Sharp Kabushiki KaishaInventor: Takeshi Wada
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Patent number: 9478798Abstract: A battery is provided with a hexacyanometallate cathode. The battery cathode is made from hexacyanometallate particles overlying a current collector. The hexacyanometallate particles have the chemical formula AXM1MM2N(CN)Z.d[H2O]ZEO.e[H2O]BND, where A is a metal from Groups 1A, 2A, or 3A of the Periodic Table, where M1 and M2 are each a metal with 2+ or 3+ valance positions, where “ZEO” and “BND” indicate zeolitic and bound water, respectively, where d is 0, and e is greater than 0 and less than 8. The anode material may primarily be a material such as hard carbon, soft carbon, oxides, sulfides, nitrides, silicon, metals, or combinations thereof. The electrolyte is non-aqueous. A method is also provided for fabricating hexacyanometallate with no zeolitic water content in response to dehydration annealing at a temperature of greater than 120 degrees C. and less than 200 degrees C.Type: GrantFiled: August 20, 2015Date of Patent: October 25, 2016Assignee: Sharp Laboratories of America, Inc.Inventors: Yuhao Lu, Jie Song, Jong-Jan Lee
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Patent number: 9476577Abstract: A backlight device according to the present invention is provided with: a chassis having a bottom plate 22a and a side plate; LED substrates 25 disposed on the bottom plate 22a of the chassis in a manner so that one end surface of the LED substrates and the side plate face each other; LEDs disposed on the LED substrates 25 with the obverse side as the light exit side; a wiring pattern 35 disposed on the LED substrates 25; a first connector 31 connected to the wiring pattern 35 and disposed on the end on the side provided with the one end surface among the ends of the LED substrates 25; a second connecting member that is electrically connected to the first connector 31 with the direction of connection being a direction that is along the plate surface of the bottom plate 22a, forming in a plan view an angle with the first side edge 22a1 that faces the one end surface, and facing the first side edge 22a1 from the reverse side from the first side edge 22a1 sandwiching the first connector 31; and a power supply wiType: GrantFiled: April 2, 2012Date of Patent: October 25, 2016Assignee: SHARP KABUSHIKI KAISHAInventor: Yasumori Kuromizu
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Patent number: 9475785Abstract: In its many embodiments, the present invention provides certain iminothiadiazine dioxide compounds, including compounds Formula (I): and include stereoisomers thereof, and pharmaceutically acceptable salts of said compounds stereoisomers, wherein each of R1, R2, R3, R4, R5, R9, ring A, ring B, m, n, p, -L1-, -L2-, and -L3- is selected independently and as defined herein. The novel iminothiadiazine dioxide compounds of the invention have surprisingly been found to exhibit properties which are expected to render them advantageous as BACE inhibitors and/or for the treatment and prevention of various pathologies related to ?-amyloid (“A?”) production. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use in treating pathologies associated with amyloid beta (A?) protein, including Alzheimer's disease, are also disclosed.Type: GrantFiled: February 27, 2015Date of Patent: October 25, 2016Assignee: Merck Sharp & Dohme Corp.Inventors: Jack D. Scott, Andrew W. Stamford, Eric J. Gilbert, Jared N. Cumming, Ulrich Iserloh, Jeffrey A. Misiaszek, Guoqing Li
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Patent number: 9479311Abstract: There are provided a terminal device, a base station device, and an integrated circuit that enable a base station device and a terminal device to determine parameters related to uplink signals or uplink reference signals and to perform efficient communication.Type: GrantFiled: March 13, 2013Date of Patent: October 25, 2016Assignee: SHARP KABUSHIKI KAISHAInventors: Tatsushi Aiba, Shoichi Suzuki, Kimihiko Imamura, Wataru Ouchi, Kazunari Yokomakura