Abstract: Improved methods of measuring gene expression in intracellularly immunostained FACS-sorted cell populations are provided. Exemplary methods involve fixing cells with formalin and permeabilizing with mild detergent in the presence of ribonucleoside vanadyl complex prior to FACS sorting, followed by RNA extraction in the presence of de-crosslinking agents. The resulting RNA is suitable for gene expression analysis. The method allows for analysis of the gene expression pattern specifically associated with any sortable cell population or subpopulation.

Abstract: The present invention relates to compounds of formula I that are useful as hepatitis C virus (HCV) NS5B polymerase inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5B polymerase activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.

Abstract: A paper feed apparatus includes a paper feeding portion that sends-out a paper placed in a paper placing tray, and is used in an image forming apparatus such as a multifunction machine. The paper feed apparatus comprises a first regulating portion and a second regulating portion that are arranged in the vicinity of a downstream side of a paper feeding position by the paper feeding portion. The first regulating portion is arranged outside a second width paper passage area to regulate a movement of a first width paper such as A4 paper placed in the paper placing tray toward a feeding direction. On the other hand, the second regulating portion is arranged inside the second width paper passage area to regulate a movement of a second width paper such as a name card placed in the paper placing tray toward a feeding direction.

Abstract: A backlight device includes: a light guide plate, at least one end face thereof being a light-receiving face; and a plurality of light-emitting units arranged in a row along the light-receiving face such that light emitted from light-emitting units enters the light-receiving face of the light guide plate, wherein the plurality of light-emitting units are grouped into a plurality of groups such that an amount of light emitted by each light-emitting unit in a center group on a center-side of the row is less than an amount of light emitted by each light-emitting unit in a peripheral group on a relatively end-side of the row.

Abstract: The invention encompasses a novel process for making piperidinone carboxamide indane and azainane derivatives, which are CGRP receptor antagonists useful for the treatment of migraine.

Abstract: By either subsampling neighbor pixels and deriving an illumination variation parameter, or deriving one normalization shift value of two normalization shift values for normalizing parameters which are used when deriving the illumination variation parameter, with a dependency on the other normalization shift value, an amount of calculation for illumination compensation is reduced.

Abstract: A liquid crystal display device, including; a liquid crystal panel; a polarizing plate attached to a surface of the liquid crystal panel; an adhesive sheet covering the polarizing plate, the adhesive sheet having a central region attached to the polarizing plate and a peripheral region attached to a peripheral surface of the liquid crystal panel, the peripheral region enclosing an entire circumference of an outer edge of the polarizing plate; and a transmissive member attached to the adhesive sheet.

Abstract: The instant invention relates to methods for the treatment of B-cell lymphomas and leukemia by administering a SYK inhibitor. In another embodiment, the invention relates to a method for treating a patient diagnosed with a B-cell lymphoma or leukemia, comprising administering a SYK inhibitor, wherein the B-cells of said patient to be treated are characterized by elevated expression levels of CD86.

Abstract: Provided is a driving control unit (93) which performs control to switch high and low of correlation of code sequences output by driving signal generation units (4a to 4d) according to a detection distance which is a distance between a surface of a touch panel (2) and an object to be detected.

Abstract: To obtain a secondary battery that surely positions and fixes a laminated type of electrode group by effectively curbing lateral deviation and vertical deviation, in secondary batteries RB1 to RB11 that include a laminated type of electrode group 1 in which a positive-electrode plate 2 and a negative-electrode plate 3 are so laminated via a separator 4 as to form a plurality of laminated layers, a structure is employed, in which vertical deviation in a lamination direction and lateral deviation in a lamination surface direction are curbed via a fix means that fixes the electrode group 1 to a predetermined position in an outer case 11 that houses the electrode group 1.

Abstract: The present invention is directed to antigen binding proteins including, but not limited to, monoclonal antibodies and antigen binding fragments thereof, that specifically bind to and preferably neutralize human cytomegalovirus (CMV). Also encompassed by the invention are antigen binding proteins that have been humanized. The antigen binding proteins of the invention are useful as a therapeutic agent for treating and/or preventing CMV infections in a patient in need thereof.

Abstract: A backlight device includes LEDs, a light guide plate, and a heat dissipation member. The light guide plate includes edge surfaces including a light entrance surface through which light from the LEDs enters, a front plate surface as a light exit surface through which the light from the LEDs exits, and another plate surface as an opposed surface on an opposite side from the light exit surface. The heat dissipation member having heat dissipating properties includes a bottom plate portion extending along the opposed surface on an opposed surface side, and an upstanding portion extending from the bottom plate portion toward the light exit surface. The bottom plate portion includes projections projecting toward the light exit surface and facing short-side edge surfaces of the light guide plate. The projections are stopped at the corresponding edge surfaces to restrict a distance between the LEDs and the light entrance surface.

Abstract: In one or more example embodiments, a display controller includes a stable pixel writing period in one horizontal period in a display device, the stable pixel writing period being a period during which a voltage outputted from a gate driver is at a high level. The display controller also includes a first stable pixel writing period determination circuit which determines, by using a reference signal independent from the frame rate in the display device, the stable pixel writing period during which the voltage is at the high level. Thus, the display controller can be provided in which, regardless of whether and how the frame rate is changed, the stable pixel writing period can be of a target length.

Abstract: In a pixel circuit, during a period during which an organic EL element is not emitting light, a transistor is in an “on” state and a reverse-direction voltage determined by a reverse-direction current that depends on the degree to which degradation of the organic EL element has progressed is written to a capacitor. The transistor then turns off, another transistor turns on, and a compensating current that depends on the reverse-direction voltage flows from another capacitor towards a reverse-biasing power-supply line, causing a drive voltage maintained by the capacitor to change by a compensating voltage change. This makes it possible to minimize decreases in the emission luminance of an electro-optical element such as an organic EL element due to degradation thereof over time.

Abstract: A shift register is disclosed which includes, at respective stages, unit circuits (11) each including (i) a flip-flop (11a) including first and second CMOS circuits and (ii) a signal generation circuit (11b) for generating an output signal (SROUTk) for the current stage with use of an output (Q, QB) of the flip-flop (11a), the shift register including a floating control circuit (11c) between a gate terminal of an output transistor (Tr7) of the signal generation circuit (11b) and a Q terminal. This makes it possible to reduce a circuit scale of a display driving circuit without causing a shift register to malfunction.

Abstract: The present invention allows a current leakage path to be reliably disconnected even when a conductive film residue occurs between data wiring lines. An interlayer insulating film of a TFT panel includes an interlayer insulating film opening at a position corresponding to a pattern edge of an insulating protective film.

Abstract: A method for decoding a video frame includes receiving a slice header of at least one of a plurality of slices, identifying a type of a first slice and a type of a second slice, and initializing a first context associated with the first slice and a second context associated with the second slice using one of a first initialization method and a second initialization method. The first initialization method or the second initialization method is selected according to the type of the first slice and the type of the second slice.

Abstract: A plurality of first sensor pixel circuits each sensing light during a sensing period when a backlight is turned on and retaining the amount of sensed light otherwise in accordance with a clock signal and a plurality of second sensor pixel circuits each sensing light during a sensing period when the backlight is turned off and retaining the amount of sensed light otherwise in accordance with a clock signal are arranged in a pixel region. The sensor pixel circuits of two types are connected to different output lines, so that a difference between two output signals is obtained at the outside of the sensor pixel circuit. The sensor pixel circuits described above are used for detecting a difference between an amount of light to be incident when the backlight is turned on and an amount of light to be incident when the backlight is turned off.

Abstract: A cathode active material of the present invention is a cathode active material having a composition represented by General Formula (1) below, LiFe1?xMxP1?ySiyO4??(1), where: an average valence of Fe is +2 or more; M is an element having a valence of +2 or more and is at least one type of element selected from the group consisting of Zr, Sn, Y, and Al; the valence of M is different from the average valence of Fe; 0<x?0.5; and y=x×({valence of M}?2)+(1?x)×({average valence of Fe}?2). This provides a cathode active material that not only excels in terms of safety and cost but also can provide a long-life battery.

Abstract: Realized is an electrostatic capacitance value distribution detecting device capable of determining whether or not external noise exists. An electrostatic capacitance value distribution detecting circuit (2) of an aspect of the present invention drives vertical signal lines (VL) to output, from horizontal signal lines (HL), electric charges corresponding to electrostatic capacitances, and then drives the horizontal signal lines to output, from the vertical signal lines, electric charges corresponding to the electrostatic capacitances. The electrostatic capacitance value distribution detecting device includes a noise detecting section (8) which determines whether or not external noise exists.