Patents Assigned to Sharp
  • 4-PYRIDINONETRIAZINE DERIVATIVES AS HIV INTEGRASE INHIBITORS
    Publication number: 20150329539
    Abstract: The present invention relates to 4-Pyridinonetriazine Derivatives of Formula (I); and pharmaceutically acceptable salts thereof, wherein A, X, Y, R1, R2, R3 and R5 are as defined herein. The present invention also relates to compositions comprising at least one 4-Pyridinonetriazine Derivative, and methods of using the 4-Pyridinonetriazine Derivatives for treating or preventing HIV infection in a subject.
    Type: Application
    Filed: December 12, 2013
    Publication date: November 19, 2015
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Mark W. Embrey, Thomas H. Graham, Abbas Walji, Sherman T. Waddell, Tao Yu, Yonglian Zhang, Wensheng Liu, Paul J. Coleman, John Wai, Thomas Steele, Christina Di Marco
  • Inhibitors of the Renal Outer Medullary Potassium Channel
    Publication number: 20150329557
    Abstract: The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and conditions associated with excessive salt and water retention.
    Type: Application
    Filed: December 13, 2013
    Publication date: November 19, 2015
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Alexander Pasternak, Reynalda Keh DeJesus, Jessica L. Frie, Barbara Pio, Haifeng Tang, Shawn P. Walsh
  • AMINO-PYRIMIDINE-CONTAINING SPLEEN TYROSINE KINASE (SYK) INHIBITORS
    Publication number: 20150329531
    Abstract: The invention provides certain amino-pyrimidine-containing compounds. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions mediated by Spleen Tyrosine Kinase (Syk) kinase.
    Type: Application
    Filed: December 9, 2013
    Publication date: November 19, 2015
    Applicant: Merck Sharp & Dohme Corp.
    Inventor: Michelle R. Machacek
  • Factor IXa Inhibitors
    Publication number: 20150329562
    Abstract: The present invention provides a compound of Formula (I) wherein R1, R2, R3 and R4 are independently H or C1-6 alkyl, provided that when R1, R2, and R3 are H, R4 is C1-6 alkyl, and when R1, R2, and R4 are H, R3 is C1-6 alkyl, and when R1, R3, and R4 are H, R2 is C1-6 alkyl, and when R2, R3, and R4 are H, R is C1-6 alkyl; and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes.
    Type: Application
    Filed: December 16, 2013
    Publication date: November 19, 2015
    Applicants: Merck Sharp & Dohme Corp., Mochida Pharmaceutical Co., Ltd.
    Inventors: Cameron James Smith, John Qiang Tan, Ting Zhang, James Balkovec, William John Greenlee, Liangqin Guo, Yi-Heng Chen, Yili Chen, Samuel Chackalamannil, Tomokazu Hirabayashi, Mika Sekioka
  • PROCESS FOR MAKING REVERSE TRANSCRIPTASE INHIBITORS
    Publication number: 20150329521
    Abstract: The present invention is directed to a novel process for synthesizing 3-(substituted phenoxy)-1-[(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl])-pyridin-2(1H)-one derivatives. The compounds synthesized by the processes of the invention are HIV reverse transcriptase inhibitors useful for inhibiting reverse transcriptase, HIV replication and the treatment of human immunodeficiency virus infection in humans.
    Type: Application
    Filed: December 4, 2013
    Publication date: November 19, 2015
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Tetsuji Itoh, Ingyu Jeon, Ian Mangion, Gang QIAN, Benjamin D. Sherry, Donald R. Gauthier, Yang CAO
  • METHOD AND BASE STATION FOR TRANSMITTING UPLINK SCHEDULING INFORMATION
    Publication number: 20150334738
    Abstract: The present invention provides a method and a base station each for transmitting uplink scheduling information. The method includes the steps of: for an uplink subframe to be scheduled in accordance with the uplink scheduling information, selecting, from a downlink subframe candidate group, a downlink subframe usable for transmission of the uplink scheduling information, the downlink subframe candidate group including (1) a first downlink subframe corresponding to the uplink subframe in accordance with a predetermined scheduling timing and (2) one or more second downlink subframes each not corresponding to the uplink subframe in accordance with the predetermined scheduling timing; and transmitting the uplink scheduling information in the selected downlink subframe.
    Type: Application
    Filed: December 25, 2013
    Publication date: November 19, 2015
    Applicant: SHARP KABUSHIKI KAISHA
    Inventors: Ziyuan GUO, Renmao LIU, Lei HUANG
  • LIQUID-CRYSTAL DISPLAY DEVICE AND METHOD FOR DRIVING SAME
    Publication number: 20150332651
    Abstract: Based on a REF/NREF signal coming from a REF/NREF determination circuit, a polarity bias calculation circuit updates a polarity bias count value Nb indicating a degree of a polarity bias of an applied voltage to a liquid crystal layer, and based on this polarity bias count value Nb, a bias movement determination circuit determines a moving direction of the polarity bias. Upon receiving an OFF signal Soff instructing OFF of the power supply, a balance control circuit controls a drive unit based on a result of the determination of the polarity bias moving direction and on the polarity bias count value Nb at a point of time when the OFF signal Soff is inputted so that the polarity bias can be resolved before a power supply is turned off.
    Type: Application
    Filed: December 20, 2013
    Publication date: November 19, 2015
    Applicant: Sharp Kabushiki Kaisha
    Inventors: Jin MIYAZAWA, Kouji KUMADA, Noriyuki TANAKA, Tatsuhiko SUYAMA, Takuya SONE
  • ELECTRONIC APPARATUS AND VACUUM CLEANER
    Publication number: 20150332675
    Abstract: An electronic apparatus of the present invention includes: a speech input section for converting an inputted speech to speech data; a speech recognition section for analyzing the speech data so as to identify a word or sentence in the speech data and calculate a certainty of the identified word or sentence; a response determining section for determining, in accordance with the certainty, whether to ask back to a user; and an asking-back section for asking back to the user, in a case where the certainty is less than a first threshold and not less than a second threshold, the response determining section determining that the electronic apparatus is going to ask back to the user, and in a case where the certainty is less than the second threshold, the response determining section determining that the electronic apparatus is not going to ask back.
    Type: Application
    Filed: December 3, 2013
    Publication date: November 19, 2015
    Applicant: Sharp Kabushiki Kaisha
    Inventors: Kazunori YASUDA, Mami YATAKE, Kazuhiro MIKI
  • BASE STATION DEVICE, WIRELESS COMMUNICATION SYSTEM, WIRELESS COMMUNICATION METHOD, AND INTEGRATED CIRCUIT
    Publication number: 20150333808
    Abstract: A base station device according to the present invention receives wireless frames transmitted by terminal devices in nearby cells, estimates the state of the propagation channels between the terminal devices in the nearby cells and itself, based on the received signals thereof, and performs precoding on transmission data addressed to terminal devices in its own cell, based on the estimation results of the propagation channel state, and transmits.
    Type: Application
    Filed: November 1, 2013
    Publication date: November 19, 2015
    Applicant: Sharp Kabushiki Kaisha
    Inventors: Takashi ONODERA, Hiromichi TOMEBA, Alvaro RUIZ DELGADO, Minoru KUBOTA
  • ELECTRIC APPARATUS
    Publication number: 20150334651
    Abstract: Provided is an electric apparatus including a reception unit (for example, hardware key) for receiving an instruction relating to functions of the electric apparatus and having operation states of a power conserving state in which power required for performing the functions thereof is limited and a normal state in which the power is not limited, wherein the reception unit may receive an instruction indicating a return to the normal state in the power conserving state and receive an instruction which is to be originally received in the normal state. When the reception unit receives the instruction, signals at different levels are output depending on the operation state and based on the signal to be output, a return signal relating to the return to the normal state or an execution signal relating to the execution of a function corresponding to the instruction received by the receiving signal is output.
    Type: Application
    Filed: April 17, 2013
    Publication date: November 19, 2015
    Applicant: SHARP KABUSHIKI KAISHA
    Inventor: Tatsuaki AMEMURA
  • SUBSTITUTED PYRROLOPYRIMIDINES AS HDM2 INHIBITORS
    Publication number: 20150329548
    Abstract: The present invention provides substituted pyrrolopyrimidines as described herein or a pharmaceutically acceptable salt or solvate thereof. The representative compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and potential methods of treating cancer using the same.
    Type: Application
    Filed: December 18, 2013
    Publication date: November 19, 2015
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Christopher Dinsmore, Francesc Xavier Fradera Llinas, Amit Ashokro Kudale, Michelle Machacek, Michael Hale Reutershan, Christopher Francis Thompason, B. Wesley Trotter, Liping Yang, Michael D. Altman, Stephane L. Bogen, Ronald J. Doll, Matthew E. Voss
  • PROCESS FOR PURIFYING INSULIN AND ANALOGUES THEREOF
    Publication number: 20150329612
    Abstract: A process is described for purifying insulin and insulin analogues that comprises high-pressure liquid chromatography with an acidic cation exchange medium performed under low to moderate pressure at an elevated temperature.
    Type: Application
    Filed: December 12, 2013
    Publication date: November 19, 2015
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Michael P. COLEMAN, Allison D. ORTIGOSA, Mark C. SLEEVI, Kartoa CHOW
  • Display panel driving method, display device driving circuit, and display device
    Patent number: 9189986
    Abstract: A method of driving a display panel having a display area including different first and second display areas includes: (1) supplying image data to each of the first and second display area by a supply circuit to display an image therein; and (2) performing a first correction to correct only the image data supplied to the first display area in the image data supplying step. The first correction is performed based on a first correction data stored in a first memory.
    Type: Grant
    Filed: February 9, 2011
    Date of Patent: November 17, 2015
    Assignee: SHARP KABUSHIKI KAISHA
    Inventor: Takashi Sasaki
  • Liquid crystal display device, display apparatus, and gate signal line driving method
    Patent number: 9190001
    Abstract: A control capacitor (CDown) is connected between a pixel electrode of a liquid crystal capacitor (CLC_Bn) in at least one sub-pixel and a common signal line (COM) through a TFT (3) whose gate electrode is connected to a gate signal line (Gn+1), and a control circuit selectively switches output modes in accordance with whether the pulse periods of a gate pulse to be output to the gate signal line (Gn) and a gate pulse to be output to the gate signal line (Gn+1) partially overlap or not.
    Type: Grant
    Filed: November 8, 2011
    Date of Patent: November 17, 2015
    Assignee: Sharp Kabushiki Kaisha
    Inventor: Tsuyoshi Kamada
  • Linear system coefficient estimation method, integrated circuit employing same, touch panel system, and electronic apparatus
    Patent number: 9189118
    Abstract: A noise removing section (101) is provided which removes noise superimposed on each of N linear sum signals of target coefficients by filtering the N linear sum signals. An estimating section (105) estimates values of the M target coefficients by calculating an inner product of (i) signals which vary in accordance with the N linear sum signals from each of which the noise has been removed and (ii) N M-dimensional vectors.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: November 17, 2015
    Assignee: SHARP KABUSHIKI KAISHA
    Inventor: Yusuke Kanazawa
  • Method and device which obtains updated system information when a component carrier has changed
    Patent number: 9191924
    Abstract: A mobile station apparatus includes a radio resource control circuit. The radio resource control circuit obtains, from a base station apparatus, system information broadcasted on a first component carrier. The radio resource control circuit also obtains, from the base station apparatus, updated system information corresponding to a second component carrier via a dedicated radio resource control signaling in a case that the system information corresponding to the second component carrier is changed.
    Type: Grant
    Filed: April 28, 2014
    Date of Patent: November 17, 2015
    Assignee: SHARP KABUSHIKI KAISHA
    Inventors: Shohei Yamada, Katsunari Uemura
  • Reception device, reception method, and program
    Patent number: 9191155
    Abstract: The present invention is capable of reducing a calculation amount while lessening performance degradation from MLD. The present invention is a reception device that receives a transmit signal which is transmitted from a transmission device by a MIMO transmission scheme. The reception device includes a channel estimation unit (205) that performs channel estimation using a received signal, and calculates a channel estimation value, a signal detection unit (206) that generates a bit log-likelihood ratio by MIMO demultiplexing of a received signal based on the channel estimation value, and a decoding unit (207) that performs error correction decoding with respect to the bit log-likelihood ratio.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: November 17, 2015
    Assignees: Sharp Kabushiki Kaisha, Tokyo Institute of Technology
    Inventors: Kazuhiko Fukawa, Hiroshi Suzuki, Satoshi Suyama, Ryota Yamada, Katsuya Kato, Takashi Yoshimoto
  • Content display device, content display method, portable terminal, program, and recording medium
    Patent number: 9189070
    Abstract: In a content display device (1) of the present invention, a scrolling processing section (107) causes a scrolling movement of a currently-displayed shelf face (11) in a lengthwise direction to be displayed in a case where a second input operation instructing display of the currently-displayed shelf face (11) in a different position in the lengthwise direction is carried out via an input operation section (111). A rotation processing section (106) causes rotation of a bookshelf object (10) on a central axis of the bookshelf object (10) to be displayed in a case where a first input operation instructing display of a shelf face (11) different from the currently-displayed shelf face (11) is carried out via the input operation section (111).
    Type: Grant
    Filed: September 21, 2011
    Date of Patent: November 17, 2015
    Assignee: Sharp Kabushiki Kaisha
    Inventors: Sunao Yamaguchi, Shinichiro Ota, Yu Matsumoto, Hironori Inoue, Masayuki Nakazawa, Toshiroh Mukai
  • Method for preparing antibodies having improved properties
    Patent number: 9187552
    Abstract: The present invention is directed to methods and compositions for the production of Fc-containing polypeptides having improved properties and comprising mutations at positions 243 and 264 of the Fc region.
    Type: Grant
    Filed: May 25, 2011
    Date of Patent: November 17, 2015
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Terrance A. Stadheim, Dongxing Zha, Liming Liu
  • Alkaline fuel cell and alkaline fuel cell system
    Patent number: 9190678
    Abstract: Provided is an alkaline fuel cell, including: a membrane electrode assembly including an anion conductive electrolyte membrane, an anode electrode stacked on a first surface of the anion conductive electrolyte membrane, and a cathode electrode stacked on a second surface opposite to the first surface of the anion conductive electrolyte membrane; a first separator stacked on the anode electrode, at least including a fuel receiving portion for receiving a fuel; a second separator stacked on the cathode electrode, at least including an oxidant receiving portion for receiving an oxidant; and an alkaline aqueous solution supply portion for bringing an alkaline aqueous solution into contact with only the anion conductive electrolyte membrane of the membrane electrode assembly.
    Type: Grant
    Filed: August 27, 2012
    Date of Patent: November 17, 2015
    Assignee: SHARP KABUSHIKI KAISHA
    Inventors: Hirotaka Mizuhata, Shunsuke Sata