Abstract: Lower eukaryotic host cells have been recombinantly engineered to produce glycoprotein having human-like O-glycosylation. The glycoproteins are useful for the production of glycoprotein compositions with advantages for the production of human therapeutics.

Abstract: Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt or solvate thereof, wherein W, X, U, R1, R2, R3, and R4, are as defined herein, and pharmaceutical compositions comprising the compounds of formula I. Also disclosed is the method of inhibiting aspartyl protease, and in particular, the methods of treating cardiovascular diseases, cognitive and neurodegenerative diseases, and the methods of inhibiting of Human Immunodeficiency Virus, plasmepins, cathepsin D and protozoal enzymes. Also disclosed are methods of treating cognitive or neurodegenerative diseases using the compounds of formula I in combination with a cholinesterase inhibitor or a muscarinic antagonist.

Abstract: A mutual capacitance touch panel device includes a substrate and an array of electrode elements formed on the substrate, each electrode element including a drive electrode and a pair of dual-function electrodes. In addition, the pair of dual-function electrodes of each electrode element are arranged substantially symmetrically around the drive electrode of the respective electrode element such that a first dual-function electrode of the pair is adjacent to the drive electrode and the second dual function electrode of the pair is separated from the drive electrode by the first dual-function electrode.

Abstract: The present invention provides a display panel with a flat plate in which a member partially provided with a light blocking part is disposed in front of a display panel, and a curable resin therebetween is sufficiently cured even in an area behind the light blocking part. The display panel with a flat plate of the present invention includes: a flat plate provided with a light passing part and a light blocking part; a display panel; and an adhesive layer between the flat plate and the display panel, the adhesive layer being a cured resin layer obtainable by polymerization involving at least one reactive component selected from the group consisting of a (meth)acrylate oligomer, a bicyclic ring-containing (meth)acrylate monomer, and a hydroxyl group-containing (meth)acrylate monomer, a peroxide component, and a primer as reaction materials.

Abstract: A touch panel system can accurately detect a position of an indicator as distinguished from noise, an electronic information device, and an indicator position detecting method are provided. An indicator position detecting portion detects a position of an indicator, which is in contact with or close to a detecting surface P, based on either one of a first or a second capacitance signal. The first capacitance signal is obtained in a first driving mode in which a first drive signal is applied to first signal lines and a first sense signal appearing on second signal lines is applied to a sense signal processing portion. The second capacitance signal is obtained in a second driving mode in which a second drive signal is applied to the second signal lines, and a second sense signal appearing on the first signal lines is applied to the sense signal processing portion.

Abstract: The instant invention provides compounds of formula I which are Jak inhibitors, and as such are useful for the treatment of Jak-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.

Abstract: This is a mold repairing method for removing a resin material deposited on a mold, of which the surface is a porous film with a plurality of recesses that have been created through anodization. The mold repairing method includes the steps of: (I) removing the resin material that is exposed on the surface of the mold over the plurality of recesses without performing atmospheric pressure plasma processing; and (II) removing at least partially the resin material that is still left inside the plurality of recesses by the atmospheric pressure plasma processing, after the step (I) has been performed, thereby recovering the original function of the mold.

Abstract: Provided is a display device and a television receiver each has a frame at a circumferential part of a display panel, the frame having a smaller level difference and a gap at a coupling section of frame members. In a display device comprising a display panel 1 that displays an image and a rectangular frame-shaped cabinet 3 that covers the display panel 1, the cabinet 3 is formed by bringing end parts of members constituting sides of a rectangular frame into contact with each other so as to couple the members with each other. A contacting end part of each of the members is provided with a regulating part that engages with a corresponding regulating part and regulates a relative movement of each of the members.

Abstract: An illumination apparatus includes a radiating fin exposed externally on an upper surface of a casing having a light source and a drive unit accommodated therein, and a securing portion to secure the casing to a ceiling surface. The radiating fin includes a ventilation path that is provided in the form of a groove located between a plurality of fin portions extending in a first direction parallel to each other and has opposite ends in the first direction, externally opened. The securing portion allows the radiating fin to be disposed with a distance from the ceiling surface. When the illumination apparatus is installed on the ceiling surface the radiating fin and the ceiling surface form a space having opposite ends in the first direction, each externally opened, and opposite ends in a second direction corresponding to a direction in which the plurality of fin portions are aligned, each externally opened.

Abstract: The present invention provides a display panel and a display device which can increase light use efficiency with a simple configuration. An optical modulation layer 30 provided between substrates 10 and 20 contains a polar solvent 31a, a nonpolar solvent 31b, and hydrophilic shape-anisotropic members 32, the hydrophilic substrate makes contact with the polar solvent 31a, the hydrophobic substrate 10 makes contact with the nonpolar solvent 31b, a projected area of the shape-anisotropic members 32 onto the substrates 10 and 20 is changed by adjusting a magnitude of a voltage to be applied to the optical modulation layer 30.

Abstract: A liquid crystal display device (10) is provided with the following: an LED (17); a liquid crystal panel (11); a light guide plate (16) disposed so as to overlap the liquid crystal panel (11); an optical member (15) disposed between the liquid crystal panel (11) and the light guide plate (16); a holding member (HM) having a frame (13) and a chassis (14) for holding in a sandwiched manner the liquid crystal panel (11), the optical member (15) and the light guide plate (16); a first object of positioning determination unit (33) disposed at the edge of the light guide plate (16); a positioning determination unit (31) disposed on the frame (13) and for determining the position of the light guide plate (16) in a direction following the plate surface by causing uneven engagement of the light guide plate with respect to the first object of positioning determination unit (33); and a light-shielding sheet (35) for blocking direct incidence of light from the first object of positioning determination unit (33) on the li

Abstract: Provided is an information display apparatus capable of smoothly performing a presentation or the like using a touch panel. The information display apparatus is able to edit display content based on a touch to the touch panel. A touch judging portion for judging whether or not the touch panel is touched, and an image edit portion for displaying a trace of the touch to the touch panel that is judged by the touch judging portion on the touch panel as an input image are included. The image edit portion deletes the input image from the touch panel automatically after a predetermined time has elapsed.

Abstract: An image forming apparatus includes a process unit, an exhaust path, and a positioning member movable between (i) a positioning position for positioning the process unit and (ii) a releasing position for releasing the process unit, the positioning member having an air path, the air path and the exhaust path being connected in a case where the positioning member is in the positioning position, and the air path and the exhaust path being disconnected in a case where the positioning member is in the releasing position.

Abstract: An LED classification device classifies LEDs, the LEDs each including a combination of an LED element that emits a primary light and a phosphor that, upon excitation by the primary light, emits a secondary light having a longer wavelength than the primary light, the LEDs each emitting a combined light of the primary light and the secondary light, those ones of the LEDs whose primary lights having their chromaticities falling within a predetermined chromaticity range being classified as LEDs for use in a backlight of a liquid crystal display apparatus. The LED classification device calculates, for all of the LEDs to be classified, correction values for the chromaticities as obtained on the assumption that the primary lights have traveled through a color filter of the liquid crystal display apparatus, and correct chromaticities by subtracting the correction values from chromaticities obtained for all of the LEDs to be classified, respectively.

Abstract: An embodiment of the present invention switches, in a display driving circuit of a liquid crystal display device which carries out CC driving, between a two-line reversal driving mode in which a polarity of a data signal supplied to a source line is reversed every two horizontal scanning periods and a one-line reversal driving mode in which a polarity of a data signal supplied to a source line is reversed every one horizontal scanning period. In at least one example embodiment, a polarity signal reverses its polarity every two horizontal scanning periods in the two-line reversal driving mode, and reverses its polarity every one horizontal scanning period in the one-line reversal driving mode.

Abstract: In a wireless communication system a base station apparatus and a mobile station apparatus communicate with each other. The base station sets the number of spatial multiplexing sequences (rank) of data being used by the mobile station when transmitting a PUSCH, further sets orthogonal resources used by the mobile station for the same number of reference signals as the set number of spatial multiplexing sequences which are transmitted together with the PUSCH, and transmits downlink control information indicating the number of spatial multiplexing sequences and information indicating the orthogonal resources for the reference signals. The mobile station receives the downlink control information, selects orthogonal resources to respectively apply to the reference signals, applies the selected orthogonal resources to generate the reference signals, and transmits the generated reference signals to the base station apparatus.

Abstract: An image forming system includes: an MFP switchable between a standby state and a power-saving state; a plurality of client computers outputting a print instruction to the MFP; and a server computer managing the MFP and the client computers. To the plurality of client computers, schedule information is input by the users of respective client computers. The server computer obtains the schedule information from the client computers and analyzes the schedule information. Based on the information resulting from the analysis, the server computer outputs an instruction to switch the MFP from the standby state to the power-saving state, to the MFP.

Abstract: Disclosed herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing the compound of Formula (I) and use of the compound in the treatment of neurodegenerative diseases or conditions such as Alzheimer's disease.

Abstract: The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of b3-adrenoceptor. Formula (I).

Abstract: The present invention provides a liquid crystal display device that can suppress a display defect due to collapse of liquid crystal alignment. The present invention provides a liquid crystal display device comprising a liquid crystal display element including a pair of substrates and a liquid crystal layer hermetically interposed between the pair of substrates, wherein the liquid crystal layer includes a p-type liquid crystal material that is homeotropically aligned with respect to surfaces of the pair of substrates when no voltage is applied; one of the pair of substrates comprises a comb-shaped electrode and a first alignment layer configured to control alignment of the p-type liquid crystal material; the other of the pair of substrates comprises a second alignment layer configured to control alignment of the p-type liquid crystal material; and the first alignment layer has an anchoring energy of not greater than 1.5×10?4 J/m2.