Abstract: The present invention is directed to novel substituted aminotetrahydropyrans of structural formula I which are inhibitors of the dipeptidyl peptidase-IV enzyme and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.

Abstract: A thin film transistor matrix device including an insulating substrate with a plurality of lines arranged on the substrate, where the lines include first lines and second lines. The device also includes a first connection line extending in a direction transverse to the plurality of lines, where the first connection line and the first lines are configured and arranged to be electrically connected to each other, as well as a second connection line extending in a direction transverse to the plurality of lines, where the second connection line and the second lines are also configured and arranged to be electrically connected to each other. The first and second connection lines are both formed on the same side of an image display region, when considered in plan view. Finally, the plurality of lines are associated, respectively, with drain bus lines and/or gate bus lines.

Abstract: The present invention provides a production method of a liquid crystal display device, and an exposure device, which can inhibit the deterioration of display quality even when the aligning treatment of an alignment layer is performed using an optical alignment method. The present invention pertains to a production method of a liquid crystal display device in which an alignment layer is provided on a substrate and two or more domains are formed in each pixel of a display region by exposing the alignment layer, wherein the production method includes the exposure step of exposing the alignment layer through a photo mask in which a plurality of light-transmitting areas are located in a stripe pattern, and wherein the exposure step is a step of exposing the alignment layer continuously while the relative position of the photo mask with respect to the substrate is moved at the time of viewing a substrate surface from the front in substantially parallel with the light-transmitting area.

Abstract: A peripheral region of a display panel includes a signal distribution device (4) for time-dividing and distributing, to output terminals (7), an output signal from a source driver. The signal distribution device (4) includes switching elements (20) for the output terminals (7). Each switching element (20) is controlled by a selection signal supplied to a control line (9) connected with a gate electrode. Each switching element (20) includes a source electrode and the drain electrode each having a comb-like shape having a stem part and branch parts extending therefrom. In at least one switching element (20), only all of or part of the branch parts overlap the control line (9) and a semiconductor layer (10). This suppresses abnormal heat generation of a source driver in a display device including the signal distribution circuit by which an output signal from the source driver is distributed to pixels in time series.

Abstract: A ruby character is displayed in an appropriate display form corresponding to characteristics of a layout of a document intended for giving of ruby characters. In a document generating apparatus, a storage portion stores information on a layout of a document as document layout data, a unification judging portion reads the document layout data stored in the storage portion, and a ruby character setting portion judges unification of a layout of the whole document based on the read document layout data to set a display form of a ruby character based on a judgment result by the unification judging portion.

Abstract: The invention provides certain cycloalkyl-fused tetrahydroquinolines of the Formula (I), and their pharmaceutically acceptable salts and esters, wherein R1, R2, R7, R8, R8a, E, Y, Z, n, u, and t are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.

Abstract: An active matrix substrate (20a) includes a plurality of pixel electrodes (18a) arranged in a matrix, and a plurality of TFTs (5) each connected to a corresponding one of the pixel electrodes (18a), and each including a gate electrode (11a) provided on an insulating substrate (10a), a gate insulating film (12a) covering the gate electrode (11a), a semiconductor layer (16a) provided on the gate insulating film (12a) and having a channel region (C) overlapping the gate electrode (11a), and a source electrode (15aa) and a drain electrode (15b) of copper or copper alloy provided on the gate insulating film (12a) and separated from each other by the channel region (C) of the semiconductor layer (16a). The semiconductor layer (16a) is formed of an oxide semiconductor and covers the source electrode (15aa) and the drain electrode (15b).

Abstract: A method and device for physiological parameter estimation, such as heart rate estimation, use a phase-locked loop to dynamically track a dominant frequency of an acoustic signal within a frequency band for the physiological parameter and estimate the physiological parameter using the dominant frequency. Because the phase-locked loop starts searching for the current dominant frequency near the most recently identified dominant frequency, the method and device rapidly incorporate slow changes in the dominant frequency that likely reflect real changes in the monitored physiological parameter while being slow to incorporate rapid changes in the dominant frequency that are likely caused by large noise. The hysteresis in phase-locked loop tracking allows the method and device to avoid physiological parameter estimation error induced by short-term large noise and quickly reacquire the dominant frequency once short-term large noise abates.

Abstract: A nonaqueous secondary battery, comprising: a positive electrode; a negative electrode; and a nonaqueous electrolyte solution, the nonaqueous electrolyte solution containing as a flame retardant a compound of the general formula (I): wherein R1 and R2, which are the same or different, each represents a group that is selected from a hydrogen atom, a lower alkyl, lower alkenyl, lower alkoxy, lower alkoxycarbonyl, lower alkylcarbonyl, lower cycloalkyl or aryl group, and that may have a substituent, or R1 and R2 taken together are a methylene group that may have a substituent, or R1 and R2 taken together form a ring structure containing a nitrogen atom to which R1 and R2 are attached, the ring structure being a five-membered or six-membered hydrocarbon ring that may have one or two oxo groups, or a five-membered or six-membered heterocycle that may further contain a nitrogen atom; n is 0 or 1; when n is 0, R3 is a group that is selected from a hydrogen atom, a halogen atom, a lower alkyl, lower alkenyl, low

Abstract: A specific color detecting section 1 includes: a comparing section 7 for comparing, with reference thresholds, color densities of color image data of plural colors in input image data, so as to judge whether or not the input image data include color image data of a specific color of an image pattern; and a threshold setting section 51 for setting calculated thresholds or theoretical thresholds as the reference thresholds, wherein the threshold setting section 51 a calculated threshold as a reference threshold if the calculated threshold is within an allowable range of the theoretical threshold, and the threshold setting section sets a theoretical threshold as a reference threshold if the calculated threshold is out of the allowable range of the theoretical threshold, the threshold setting section being configured to calculate out the calculated thresholds for the reference thresholds from reference image data obtained by reading out a reference chart having plural colors in predetermined color densities, and

Abstract: An image data converting device of at least one embodiment of the present invention for converting, by linear interpolation, input image data having a predetermined resolution into delta arrangement image data having a resolution that is smaller than the predetermined resolution, the image data converting device includes: an even line pixel value converting section for converting a value of each pixel in each even line in the input image data into a value of each pixel in each even line in the delta arrangement image data, by using a predetermined initial value for even lines; and an odd line pixel value converting section for converting a value of each pixel in each odd line in the input image data into a value of each pixel in each odd line in the delta arrangement image data, by using a predetermined initial value for odd lines, the predetermined initial value for odd lines being (1±?)/2(0???0.5) of the initial value for the even lines.

Abstract: The present invention is directed to isonicotinamide compounds which are antagonists of orexin receptors, and which are useful in the treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which orexin receptors are involved.

Abstract: The semiconductor integrated circuit according to the present invention includes a mode switching circuit for switching an operation mode of a main core circuit among a plurality of internal circuits between a normal operation mode and a stand-by mode; and a stand-by canceling circuit for instructing the mode switching circuit to cancel a stand-by mode, and the mode switching circuit and the stand-by canceling circuit are configured to operate in asynchronism with the system clock with stand-by voltage in the stand-by mode. Thus, the semiconductor integrated circuit is capable of achieving operations with reduced power consumption with restrained leakage current by further reducing power source voltage during a stand-by mode, while maintaining advantages of shortening a time required to return from the stand-by mode, and of requiring no additional circuitry, such as non-volatile memory, for returning from the stand-by mode and thus requiring no extra cost.

Abstract: The technology presented herein has a feature of providing a liquid crystal display device of an excellent viewing angle characteristic and high brightness, including: liquid crystals containing polymerizable monomers between a first substrate with a pixel electrode having micro slits and a second substrate facing the first substrate; wherein the monomers are polymerizable with voltage applied to the liquid crystals; and an alignment orientation of the liquid crystals is controllable to a direction of extending the micro slit, wherein the pixel electrode includes: a direct coupling part electrically connected to a switching element; a capacitive coupling part electrically insulated from the switching element, and a space between the direct and capacitive coupling parts, wherein directions in which the micro slits are extended along the direct and capacitive coupling parts are orthogonal to each other.

Abstract: A device for measuring adhesion of toner to carrier containing a magnetic component, the toner and the carrier being contained in a two-component developer, includes: a developer holding section including a first magnet for holding the two-component developer by a magnetic force; an airflow supply section for supplying airflow to the two-component developer held by the first magnet; a separated toner detecting section for detecting the number of toner separated from the carrier by the airflow; and an adhesion calculating section for calculating the adhesion of the toner to the carrier or an index of the adhesion, based on wind speed of the airflow and the detected number of the separated toner. Thus, the device can measure the adhesion of the toner to the carrier with high reproducibility and exactness.

Abstract: A class of macrocyclic compounds of formula (I), wherein R1, R3, R4, Ra, Rb, A, B, Z, M, W and n are defined herein, that are useful as inhibitors of viral proteases, particularly the hepatitis C virus (HCV) NS3 protease, are provided. Also provided are processes for the synthesis and use of such macrocyclic compounds for treating or preventing HCV infection.

Abstract: A display device includes a photosensor (81) in a pixel region (1) of an active matrix substrate (100). The photosensor (81) includes a photodetection element, reset signal wiring that supplies a reset signal RS to the photosensor (81), readout signal wiring that supplies a readout signal RW to the photosensor (81), and a sensor switching element for reading out the potential of the storage node to output wiring as sensor circuit output, the potential of the storage node having changed in accordance with the amount of light received by the photodetection element in a sensing period, the sensing period being from when the reset signal is supplied until when the readout signal is supplied. The potential of wiring having a parasitic capacitance with the storage node is fixed to a predetermined potential V0 at least either one of immediately before the readout signal RW and immediately before the reset signal RS.

Abstract: The active matrix substrate includes: a plurality of switching elements provided on an insulating substrate; a plurality of lines provided on the insulating substrate and connected to the switching elements; an interlayer insulating film covering the switching elements and the lines; a plurality of pixel electrodes formed on the interlayer insulating film; and a plurality of terminals connected to the lines and placed with a predetermined spacing. At least part of each of the terminals is not covered with the interlayer insulating film. A reflection layer configured to reflect light is provided in a region that is at least part of each gap between the adjacent terminals and includes an edge of the interlayer insulating film, as viewed from the normal to the surface of the insulating substrate.

Abstract: An active matrix substrate has a structure that prevents a drain extraction line from breaking without a plurality of active elements such as thin film transistor elements, metal-insulator-metal elements, MOS transistor elements, diodes, and varistors being disposed, and is suited for use in a large-size liquid crystal television or a like liquid crystal display device equipped with a large-size liquid crystal display panel. The active matrix substrate includes an active element connected, via a drain extraction line, to a storage capacitor upper electrode, wherein the drain extraction line has at least two routes.