Abstract: A display device includes: light-emitting elements in a backlight divided into a plurality of areas, the light-emitting elements being arranged in such a manner as to correspond to the plurality of areas; and a drive unit configured to drive the light-emitting elements in the plurality of areas by time division based on an input image every prescribed period of time, the drive unit turning on all the light-emitting elements in the plurality of areas in a partial period of the prescribed period of time and driving those light-emitting elements in at least one of the plurality of areas based on the input image in a remaining period of the prescribed period of time.

Abstract: A heat exchanger placed in front of an air blower is appropriately supported by a cabinet. In an indoor unit, the heat exchanger is placed only in front of a rotation center of an air-blowing fan. The cabinet includes: an upper left protrusion and an upper right protrusion protruding forward from an upper portion of the cabinet; and a lower left protrusion and a lower right protrusion protruding forward from a lower portion of the cabinet, so that the protrusions support the heat exchanger.

Abstract: A display device includes a first display region, a second display region, a curved portion provided between the first display region and the second display region, a plurality of first control lines provided in the first display region and extending in a first direction in which the first display region and the second display region are arranged side by side, and a plurality of second control lines provided in the second display region and extending in the first direction. The first control lines and the second control lines are electrically connected via curved portion wiring lines formed in the curved portion.

Abstract: A method of determining the result of an assay in a microfluidic device includes the steps of: dispensing a sample droplet onto a first portion of an electrode array of the microfluidic device; dispensing a reagent droplet onto a second portion of the electrode array of the microfluidic device; controlling actuation voltages applied to the electrode array to mix the sample droplet and the reagent droplet into a product droplet; sensing a dynamic property of the product droplet; and determining an assay of the sample droplet based on the sensed dynamic property. The dynamic property is a physical property of the product droplet that influences a transport property of the product droplet on the electrode array. Example dynamic properties of the product droplet include the moveable state, split-able state, and viscosity based on droplet properties. The method may be used to perform an amoebocyte lysate (LAL) assay.

Abstract: A reflective display apparatus is provided. The reflective display apparatus includes a textured sub-micron metal film textured in a periodic manner, a phase change material (PCM) layer, and a phase change control layer that is configured to change reflection properties of the textured sub-micron metal film by causing the PCM to switch between at least two of a plurality of phases.

Abstract: In an image display device, a scattering unit has a size that covers a surface of a red conversion unit on a side that emits light having a second wavelength and a surface of a green conversion unit on a side that emits light having a third wavelength, and faces at most a part of a micro LED element.

Abstract: The present disclosure provides an in vitro cell based potency assay to determine the relative potency of a composition, including a pharmaceutical composition, comprising an mRNA encapsulated in a lipid nanoparticle (LNP) as compared to a reference sample. Also provided is a process for releasing or accepting a batch of a pharmaceutical composition comprising an mRNA encapsulated in an LNP using the in vitro cell based potency assay. The methods and processes described comprise (i) transfecting a population of cells with a test sample of the composition, (ii) transfecting a different population of cells with a reference sample of the pharmaceutical composition, wherein the cells in step (ii) are the same cell type as the cells in step (i); (iii) detecting the amount of expression of a polypeptide encoded by the mRNA in the transfected cells; and comparing the amount of expression, thereby determining the relative in vitro potency of the composition.

Abstract: Systems, devices and methods to improve safety and efficiency in an operating room comprise providing a suture package that holds new suture needles and needle receptacles for storing used needles. The devices can be safely worn for the surgeon to self-dispense new suture needles in the near surgical field and to secure the used needles into a needle trap or a needle retainer located on his extremity, on his operative instruments or on the surgical drapes. The device may provide automated and/or simplified needle counting both during use and after removal from the surgical field. The device may be configured for ergonomic and efficient use so as to minimize the actions and motions of the surgeon to dispense and secure the needle.

Abstract: Provided herein are cyclic polypeptide compounds that can, e.g., bind specifically to human proprotein convertase subtilisin/kexin type 9 (PCSK9) and optionally also inhibit interaction between human PCSK9 and human low density lipoprotein receptor (LDLR), and pharmaceutical compositions comprising one or more of these compounds. Also provided are methods of reducing LDL cholesterol level in a subject in need thereof that include administering to the subject one or more of the cyclic polypeptide compounds or a pharmaceutical composition provided herein.

Abstract: The present invention relates to tyrosine-specific functionalized insulin analogs and processes of making such tyrosine-specific functionalized insulin analogs using R-3H-1,2,4-triazoline-3,5-(4H)diones (PTAD).

Abstract: Air-cleaning control is performed in accordance with a situation of motion of a person and brightness in a room.

Abstract: A display panel includes a second display region and a first display region which are arranged side by side in a direction in which data signal lines extend, and a source driver is provided at one edge of the second display region. Switches are provided between data signal lines in the first display region and data signal lines in the second display region, and the switches are turned off when an on-level scanning signal is applied to a scanning signal line in the second display region. A period during which the on-level scanning signal is applied to each scanning signal line in the second display region is shorter than a period during which the on-level scanning signal is applied to each scanning signal line in the first display region.

Abstract: The present invention provides a liquid crystal alignment agent having high thermal stability and high solvent solubility, and a liquid crystal panel in which occurrence of ghosting and stain and a decrease in contrast are suppressed even under environments at high temperatures long period of time. The present invention is a liquid crystal alignment agent including a copolymer including a structure represented by a chemical formula (1) below, and a solvent. In the formula, X is a specified structure including a cyclic hydrocarbon group, Y1 is a specified structure including a cyclic hydrocarbon group, R1 represents a homogeneous alignment group, a homeotropic alignment group, or a photoreactive functional group, and Z1 and Z2 are the same or different, and represent an —NH— group, an —O— group, or a —S— group.

Abstract: A layout pattern of a demultiplexer circuit of a display device employing the SSD method is configured as described below. Specifically, demultiplexers in the demultiplexer circuit are grouped with three demultiplexers as one set, and nine transistors as switching elements included in the three demultiplexers of each set are arranged to be aligned in the extending direction of a source line with three transistors as a unit while positions of the nine transistors are sequentially shifted in the vertical direction with respect to the source line. Furthermore, any two adjacent sets are arranged such that a direction in which nine transistors included in one set are shifted in the vertical direction with three transistors as a unit and a direction in which nine transistors in the other set are shifted in the above-described vertical direction with three transistors as a unit are opposite to each other.

Abstract: An optical scanning device includes: a light source; a light source driver that provides the light source with a drive current, on which a bias current that fluctuates according to temperature change is superimposed, for emitting light from the light source; and a bias current adjuster that provides the light source driver with a bias control signal for adjusting a magnitude of the bias current, wherein the bias current adjuster includes a current value adjusting member that is capable of changing the magnitude of the bias control signal according to temperature change, and wherein the bias control signal that has automatically changed according to temperature change of the current value adjusting member is provided to the light source driver, so that the light source driver makes the magnitude of the bias current to be superimposed fluctuate, based on the provided bias control signal.

Abstract: An ultraviolet (UV) absorbance assay for measuring the concentration of large RNA molecules such as mRNA in suspensions comprising RNA-lipid nanoparticles (RNA-LNPs) is described.

Abstract: The present disclosure relates to compounds of formula (I) that are useful as modulators of ?7 nAChR, compositions comprising such compounds, and the use of such compounds for preventing, treating, or ameliorating disease, particularly disorders of the central nervous system such as cognitive impairments in Alzheimer's disease, Parkinson's disease, and schizophrenia, as well as for L-DOPA induced-dyskinesia and inflammation.

Abstract: Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof: (I). Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO- and/or TDO-associated disease or disorder.

Abstract: A pixel circuit of a display device Includes: an electro-optical element; a drive transistor; a write control transistor; a threshold compensation transistor; two light emission control transistors; a first initialization transistor having a first conduction terminal connected to a gate terminal of the drive transistor, a second conduction terminal to which an initialization voltage is applied, and a gate terminal connected to a first initialization control line; and a capacitor provided between a first conductive member and the gate terminal of the drive transistor. In a non-light emission period, time during which a voltage of the first initialization control line is at an on-level is longer than a period during which a voltage of a scanning line is at the on-level. As a result, a display device capable of sufficiently initializing the gate terminal of the drive transistor is provided.

Abstract: The information processing apparatus includes a display. The information processing apparatus accepts user operations via a GUI (graphical user interface) displayed on the display. The operation screen is displayed on the display. On the operation screen, an operation guidance portion, including a message for providing operation guidance to the user, and a plurality of operation keys for accepting user operations are displayed. A part of the operation guidance portion is colored in a first color, the operation keys which are the first type of operation key are colored in the first color, and the operation keys which are the second type of operation key are not colored in the first color.