Patents Assigned to Shimadzu Corporation
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Patent number: 6417920Abstract: A particle size analyzer based on laser diffraction method is formed of an irradiation optical system for irradiating laser beam to particles, a measurement optical system for measuring a space intensity distribution by receiving light diffracted/scattered by the particles of the laser beam from the irradiation optical system, and an operation portion for obtaining a particle size distribution of the particles from the results measured by the measurement optical system. The irradiation optical system has a semiconductor laser in an output beam wavelength of 300 to 500 nm as a light source. Thus, particles having diameters of the order of sub-microns can be measured.Type: GrantFiled: October 31, 2000Date of Patent: July 9, 2002Assignee: Shimadzu CorporationInventor: Haruo Shimaoka
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Publication number: 20020086442Abstract: Respective monoclonal antibodies are fixed into respective wells of a microplate one by one, and bonded with labeled analogs of PTH amino acid derivatives. A solution containing PTH amino acid derivatives obtained by Edman degradation is dripped on to the microplate for causing competitive reaction to the monoclonal antibodies with the analogs, and thereafter non-bonded PTH amino acid derivatives and liberated analogs are washed out. Then enzyme-labeled antibodies against the analogs are added and the quantity of bonded enzyme-labeled antibodies is measured thereby determining the types and quantities of the PTH amino acid derivatives. Constitutive amino acid can be detected in high sensitivity.Type: ApplicationFiled: December 17, 2001Publication date: July 4, 2002Applicant: Shimadzu CorporationInventor: Hideshi Fujiwake
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Patent number: 6413747Abstract: If polyamine is caused to be present in the reacting system for the synthesis of nucleic acids to amplify target genes from a sample, the inhibition of the synthesis due to impurities in the sample can be reduced and the target genes can be effectively synthesized.Type: GrantFiled: September 12, 1997Date of Patent: July 2, 2002Assignee: Shimadzu CorporationInventors: Shingo Kato, Naoyuki Nishimura
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Publication number: 20020080351Abstract: In an atomic absorption photometer, depending on a fact whether a background correction is carried out or not, a pattern of a pulse lighting of light sources and a timing of sampling a light receiving signal are changed. Namely, at the time of a background correction measurement, one cycle is divided into three periods, that is, a period of lighting HCL, a period of lighting D2L, and an off period, and at the time of a measurement without a background correction, one cycle is divided into the period of lighting HCL and the off period. Accordingly, at the time of the measurement without the background correction, the period of lighting HCL and the off period become longer, and signal-to-noise ratio of the light receiving signal is improved. Accordingly, an absorbance with high accuracy can be calculated.Type: ApplicationFiled: December 4, 2001Publication date: June 27, 2002Applicant: SHIMADZU CORPORATIONInventor: Masumi Sakai
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Patent number: 6411674Abstract: In a radiation tomography device, in case a wide photographing area is required, even if a resolution capability in a depth direction of a section of a subject including an intersection of a rotation axis and a radiation irradiating axis is low, a small Laminographic angle &agr;1 is set. In case a high resolution capability is required in the depth direction, even if the photographing area is narrow, a large Laminographic angle &agr;2 is set. Since a balance between the resolution capability in the depth direction of the subject and the photographing area can be adjusted by varying the Laminographic angle, the photographing modes can be freely selected to thereby carry out the tomography suitable for the photographing requirement.Type: GrantFiled: April 25, 2000Date of Patent: June 25, 2002Assignee: Shimadzu CorporationInventor: Shiro Oikawa
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Patent number: 6408684Abstract: A detection device for an apparatus for carrying out analysis such as a chromatograph includes not only a detector for outputting detection signals but also a stabilization judging unit for measuring drift and noise of these detection signals over time and automatically transmitting a start signal which permits the apparatus for analysis to start its operations when the measured drift becomes smaller than a standard drift value such as one-tenth of the optical absorbance measured for a spectrum of an analyzed sample at the detection wavelength. A standard noise value setting unit may be further provided for receiving detection signals at detection wavelength while a standard sample is placed inside a detection cell, calculating a standard noise value on the basis of intensity of the detection signals, and transmitting the calculated standard noise value to the stabilization judging unit.Type: GrantFiled: January 21, 2000Date of Patent: June 25, 2002Assignee: Shimadzu CorporationInventor: Hajime Bungo
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Patent number: 6409382Abstract: A mobile X-ray apparatus for a circuit examination, which includes an X-ray tube with a collimator, a mobile base having a pair of driven wheels, a holder attached and movable to the base, the holder holds the X-ray tube. A motor driver is disposed in the base which drives the wheels. An operation handle bar is disposed in the base providing a signal for driving the motor driver. An input means, separated from the handle bar, provides a signal for driving the motor driver slightly. A controller controls the motor driver according to the signal from the handle bar or the input means.Type: GrantFiled: March 28, 2001Date of Patent: June 25, 2002Assignee: Shimadzu CorporationInventors: Koji Akutsu, Tatsuya Araki, Kimihiro Takahama, Toshio Kadowaki, Hajime Takemoto
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Publication number: 20020074491Abstract: The present invention proposes a liquid chromatograph/mass spectrometer constructed to present a maximized or almost maximized ion-producing efficiency of APCI, irrespective of whether positive or negative ions are produced. In an embodiment of the invention, two discharging electrodes 222, 223 for ionizing solvent gas molecules are disposed ahead of a sprayer 221 for spraying sample droplets; one electrode is disposed at the position optimal to the positive ion production, and another electrode is disposed at the position optimal to the negative ion production. In the analyzing operation, the same high voltage is applied to the discharging electrodes 222, 223 to generate corona discharge. According to whether positive or negative ions are to be produced, one of the discharging electrodes dominantly contributes to the ionization. Thus, the ion-producing efficiency is almost maximized irrespective of whether positive or negative ions are produced.Type: ApplicationFiled: December 13, 2001Publication date: June 20, 2002Applicant: Shimadzu CorporationInventor: Mitsuaki Fukuda
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Publication number: 20020074490Abstract: The present invention proposes a liquid chromatograph/mass spectrometer (LC/MS) constructed so that only necessary data are efficiently collected, and that the apparent dynamic range and/or the operational condition of the MS part is appropriately changed according to the concentrations and/or the qualitative information of the sample components coming from the LC part. In the LC/MS, the passage of the carrier liquid is designed so that the carrier liquid containing the sample is first introduced to an auxiliary detector and then to a main detector (mass spectrometer) with a delay of a preset time period. During the analysis, a controller constructs a chromatogram from the output signal of the auxiliary detector and analyzes its waveform to determine in real-time a time period ts0-te0 corresponding to each peak in the chromatogram.Type: ApplicationFiled: December 13, 2001Publication date: June 20, 2002Applicant: Shimadzu CorporationInventor: Yoshikatsu Umemura
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Publication number: 20020074492Abstract: In an ion trap mass spectrometer, between an ion supply source and an ion trap, there are disposed an entrance gate electrode, an ion storing section for holding ions by accumulating them near an exit side by means of an RF voltage with an axial electric potential field inclined from an entrance side to the exit side, and an exit gate electrode. When the ions are accumulated near the exit side, the exit gate electrode is opened to thereby introduce the ions in the pulse state into the ion trap. At this point, a voltage is not applied to a ring electrode of the ion trap, so that repulsion due to the voltage of the ring electrode is eliminated. Thereafter, when maximum amount of ions stay inside the ion trap, ring RF voltage is suddenly applied. Thus, the maximum amount of the ions can be introduced into the ion trap.Type: ApplicationFiled: November 13, 2001Publication date: June 20, 2002Applicant: SHIMADZU CORPORATIONInventor: Junichi Taniguchi
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Patent number: 6407547Abstract: A biaxial flux gate type magnetic sensor has a core which is made of a magnetic thin film in the shape of a loop, patterned upper and lower electrically conductive thin-film layers respectively above and below this core each with an insulating layer in between, and electrically conductive connecting members each extending between and electrically connecting these upper and lower electrically conductive layers. These upper and lower electrically conductive layers are patterned and the contact portions connect them such that they together provide an excitation coil and four detection coils. These coils are each formed so as to be wound helically and uniformly around and along a circumferential direction of the loop-shaped core by passing both inside and outside the loop. The loop is of a shape which is symmetrical with respect to two mutually perpendicular directions and is divided into four mutually symmetric sections.Type: GrantFiled: August 31, 1999Date of Patent: June 18, 2002Assignee: Shimadzu CorporationInventors: Yasuharu Yamada, Kenichi Yoshimi
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Patent number: 6407374Abstract: A two-dimensional array type detecting device of the invention is formed of a detecting side substrate, and a readout side substrate laminated together. In the detecting side substrate, a high resistivity responsive semiconductor film is laminated on a substrate through a common electrode therebetween, and semiconductor films for connection are formed for the respective sections corresponding to a two-dimensional array arrangement. Therefore, leak and expansion of carriers produced in the high resistivity responsive semiconductor are prevented in a direct conversion system, wherein light or radiation enters from a side of the glass substrate, in which the common electrode is not formed. Thus, a detecting sensitivity and space resolution can be improved. Namely, a dynamic range is large, and a crosstalk is small.Type: GrantFiled: August 29, 2000Date of Patent: June 18, 2002Assignee: Shimadzu CorporationInventors: Toshiyuki Sato, Satoshi Tokuda, Kenji Sato, Junichi Suzuki, Shinya Hirasawa, Naoyuki Hori, Toshinori Yoshimuta, Hidetoshi Kishimoto
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Publication number: 20020068292Abstract: An object of the present invention is to provide a method capable of removing contaminants other than nucleic acids derived from feces at high efficiency, and thereby obtaining nucleic acids with high purity, although it is difficult to purify nucleic acids in high purity from feces.Type: ApplicationFiled: June 19, 2001Publication date: June 6, 2002Applicant: SHIMADZU CORPORATIONInventor: Kouichi Kojima
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Patent number: 6399950Abstract: In a two-dimensional radiation detector of the invention, a semiconductor layer for converting a radiological image or light image converted therefrom to a picture image of charges by sensing X-ray, and a switching element matrix are integrally formed. A bias electrode common to a signal electrode of the semiconductor layer is connected to a bias power source through a switch or a resistance. An electric current flowing through the bias electrode from the bias power source is detected by a detector, and supplied to a control circuit. The control circuit compares a detected value supplied from the detector with a threshold value, and turns off the switch when the detected current value reaches the threshold value to shut off application of the bias voltage to the bias electrode.Type: GrantFiled: November 27, 2000Date of Patent: June 4, 2002Assignee: Shimadzu CorporationInventors: Yutaro Kimura, Takayuki Takemoto
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Patent number: 6399197Abstract: The object of the present invention is to provide a monofilament which has sufficient mechanical strength to be practically used also as a string for rackets and which is excellent in workability. Disclosed is a monofilament which is formed by extruding a material prepared by blending mainly a polylactic acid type polymer (A) and an aliphatic polyester (B) other than polylactic acid, and drawing the extruded material. This could be used as a racket string which has a tenacity-elongation curve similar to that of natural gut and is excellent in water resistance and heat resistance.Type: GrantFiled: April 26, 2000Date of Patent: June 4, 2002Assignees: Shimadzu Corporation, Gosen Co., Ltd.Inventors: Takeshi Kanamori, Hiroshi Urayama, Yoshiyuki Ohara, Tameyuki Nagano
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Patent number: 6396899Abstract: A fluorescent X-ray analyzing apparatus includes a secondary target device therein. The secondary target device includes a target main body, and an X-ray blocking member for preventing an irradiation of primary X-rays from a X-ray source to a sample. The target main body is formed of plural target members in which secondary target materials are formed on at least target surfaces facing a central axis, and the target members are arranged concentrically to have different distances from the central axis. Accordingly, the primary X-rays do not pass through a space between the target members, and are irradiated only at the target surfaces of the target members. The secondary X-rays from the target surfaces pass through the space between the target members, and reach the sample.Type: GrantFiled: April 6, 2001Date of Patent: May 28, 2002Assignee: Shimadzu CorporationInventor: Shoji Kuwabara
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Publication number: 20020060742Abstract: A solid state imaging device including a plurality of two-dimensionally arrayed light receiving pixels which generate electrical charges according to the strength of the incident light; at least two accumulating pixels for each of the light receiving pixels for accumulating signal electrical charges generated by the light receiving pixel, so that a plurality of frames of different times can be stored; a light shield for shutting off light entering the accumulating pixels and having an aperture at each of the light receiving pixels; and an opaque cover having a low reflectivity and laid over the light shield. The low reflectivity opaque cover, or the anti-reflection cover, has the same pattern as the light shield. Thus the incident light hardly reflects on the anti-reflection cover, and the harmful multiply reflecting lights are minimized. Further, the incident light hardly passes through the anti-reflection cover.Type: ApplicationFiled: November 7, 2001Publication date: May 23, 2002Applicant: Shimadzu CorporationInventor: Kenji Takubo
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Publication number: 20020055824Abstract: A device name data storing area and a measurement date-and-time data storing area are provided in a data file for storing measurement data. When measurement data are stored, the device name data and the measurement date-and-time data are also stored at the same time. A combination of the device name and the measurement date-and-time corresponds to only one measurement. Therefore, even if the file name and the measurement date-and-time contained in the data file are altered or falsified later, when the device name and the measurement date-and-time in the file are read, it can be easily determined whether at least the file is desired one or not.Type: ApplicationFiled: October 18, 2001Publication date: May 9, 2002Applicant: SHIMADZU CORPORATIONInventor: Masayuki Shibata
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Publication number: 20020050821Abstract: An NMR device includes an NMR coil, and a sample flow path connected to a sample supply source and passing through the NMR coil. The NMR device can carry out an on-line measurement so that a portion passing through the NMR coil of the sample flow path functions as an NMR probe for measurement. A filler for absorbing a sample is provided at a position of the NMR probe in the sample flow path, and the NMR measurement is carried out in a state where the sample is absorbed by the filler. Thus, when the measurement is carried out, the sample is retained accurately at the NMR coil position while a very small quantity of sample is being concentrated.Type: ApplicationFiled: October 18, 2001Publication date: May 2, 2002Applicant: SHIMADZU CORPORATIONInventor: Yosuke Iwata
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Publication number: 20020046949Abstract: A table is used to position eight specimen reservoirs of an electrophoretic chip into which a specimen is firstly dispensed to a specimen dispensing position. A specimen dispensing mechanism is used to move a head to thereby suck a test-specimen contained in eight different wells of specimen plates into eight nozzles respectively and then move the head to the specimen dispensing position, thus dispensing the test-specimen sucked into the nozzles into the specimen reservoirs simultaneously. The table is used to sequentially position the specimen reservoirs to the specimen dispensing position and then the specimen dispensing mechanism is used to sequentially dispensing the specimen into the specimen reservoirs.Type: ApplicationFiled: October 22, 2001Publication date: April 25, 2002Applicant: Shimadzu CorporationInventors: Shin Nakamura, Toru Kaji, Rintaro Yamamoto