Abstract: An eye lens material preventing protein adsorption is manufactured by reacting in a reaction medium of either water, an organic solvent, or a water/organic solvent mixture an eye lens material having OH groups with a phosphorylcholine group-containing compound of formula (1), thereby forming an acetal bond according to formula (2) which covalently bonds the phosphorylcholine group-containing compound to a surface of the eye lens material.

Abstract: An oil-in-water emulsified sunscreen cosmetic which contains: (A) Containing the following three types of surfactants (A-1)-(A-3); (A-1) A POE stearic ester having a POE mole number of 20-120; (A-2) sorbitan tristearate; and (A-3) glyceryl stearate having a HLB of 5-8; (B) bis-ethylhexyloxyphenolmethoxyphenyltriazine and/or tert-butylmethoxybenzoylmethane, oil soluble ultraviolet absorbents, solid at room temperatures; (C) ethylhexyl methoxycinnamate and/or octocrylene, oil soluble ultraviolet absorbents, liquid at room temperature; (D) phenylbenzimidazolesulfonic acid, a water soluble ultraviolet absorbent; and (E) a higher alcohol having 14-24 carbon atoms.

Abstract: The present invention is an oil-in-water emulsion composition containing a hydrophilic non-ionic surfactant or hydrophilic anionic surfactant, a higher aliphatic alcohol, water, and an oil ingredient which meets specific conditions. This is an oil-in-water emulsion composition with good high temperature stability and usability, and can be used as a cream-like endermic liniment such as a cosmetic.

Abstract: An eyelash cosmetic according to present invention, by blending (a) wax and/or (b) resin, and (c) hollow powder, can impart a voluminous feeling and, at the same time, perform excellent curling effect and curl retaining effect, and excellent usability such as easiness eyelash coating, and easiness overlaying, and also perform excellent uniformity of finishing, water resistance and oil resistance after coating.

Abstract: An emulsified composition for hair, which contains a nonionic surfactant that is a solid at normal temperature and has a Krafft point of at least 40° C., an oil component, and water, and which has an average emulsified particle size of 0.5 ?m or less, provides long-lasting luster. Further, an emulsified composition for hair, which is an water-in-oil emulsified composition and which contains the following two types of oil phase as the oil phase, improves the feel of hair immediately after use: 1) an oil phase with an average particle size of 0.5 ?m or less, formed with a nonionic surfactant that is a solid at normal temperature and has a Krafft point of at least 40° C., and 2) an oil phase with an average particle size of 0.5 to 100 ?m, formed with a surfactant and/or an alkyl-modified carboxyvinyl polymer.

Abstract: The present invention provides a modified powder that is obtainable by coating the surface of a base powder with a hydrophobizing agent and a cationic surfactant. In the modified powder described above, it is preferable that the amount of coated hydrophobizing agent and the amount of coated cationic surfactant are 3 to 90% by mass and 0.5 to 10% by mass, respectively, relative to the self weight of the base powder. In the modified powder described above, it is preferable that the mass ratio of the coated hydrophobizing agent and the coated cationic surfactant is from 1:1 to 9:1. In addition, the present invention provides a cosmetic composition comprising the above modified powder wherein the modified powder and the base powder have an ultraviolet scattering effect. In the cosmetic composition described above, it is preferable that the blended amount of the modified powder is from 0.5 to 100% by mass.

Abstract: There is provided a therapeutic agent for treating osteoarthritis, which is a drug comprising hyaluronan as an active ingredient. The hyaluronan is preferably a tetrasaccharide including two units, with a single unit being -D-glucuronic acid-?-1,3-D-N-acetylglucosamine-?-1,4- (HA4).

Abstract: A skin treatment composition of the present invention is an external composition for skin comprising an alkylene oxide derivative expressed by Formula (I): R1O-[(AO)m(EO)n]—R2??(I) wherein AO is an oxyalkylene group of C3 or C4; EO is an oxyethylene group; m and n are 1?m?70 and 1?n?70 respectively, wherein EO is 20˜80% by weight with respect to a total of AO and EO; each of R1 and R2 is a hydrogen or a hydrocarbon group having C1-4. The alkylene oxide derivative (I) has a moisturizing effect, a rough skin improving effect, a stickiness improving effect, and a transdermal absorption promoting effect. When a refreshing agent is used together therewith in the composition of the present invention, the refreshing effect lasts for a long time and it is excellent in feeling of use without skin stimulation.

Abstract: The present invention provides a dispersion of microparticulate titanium oxide that can generate a natural finish feeling, which includes a feeling of transparency, and has good long-term stability and an excellent UV protective effect in both UVA and UVB regions. The present invention is a dispersion of microparticulate titanium oxide characterized in that the microparticulate titanium oxide with the average major axis of 30 to 100 nm and the average minor axis of 8 to 50 nm is dispersed, by maintaining the average size of dispersed particles to be 80 to 110 nm, in a hydrophobic dispersion medium. In the dispersion of microparticulate titanium oxide, the content of silicone oil relative to the total hydrophobic dispersion medium is preferably 10 to 100 weight %. Furthermore, it is preferable that the dispersion of microparticulate titanium oxide contains a biterminally-siliconized polyglycerin as a dispersant. The dispersion of microparticulate titanium oxide can be preferably contained in a cosmetic.

Abstract: A complex powder comprising an adsorption site and operation site, wherein said adsorption site attracts or adsorbs a specific enzyme, wherein said operation site inhibits or activates said enzyme, and wherein each of the both sites are appeared on the surface of the powder. In the complex powder described above, it is preferable that ?-potential of the adsorption site at the pH employed is negative value, wherein said adsorption site attracts or adsorbs the specific enzyme whose ?-potential is positive value, and wherein said adsorption site inhibits or activates said specific enzyme. And it is preferable that said adsorption site has ?-potential at pH7.5 of ?10 mV or below. In the complex powder described above, it is preferable that said specific enzyme is a plasminogen activator, and the operation site inhibits said plasminogen activator. The complex powder described above can be used as an external composition for improving a rough skin and an external composition for a sensitive skin.

Abstract: A lip categorizing method uses the size and shape of the lips as viewed from the front of the face as a first categorization index and the three-dimensional form of the lips as a second categorization index. The lip categorizing map is composed of a first coordinate axis showing the degree of the first categorization index and a second coordinate axis showing the degree of the second categorization index and has a coordinate system in which the first and second coordinate axes are orthogonal. It also generates makeup information for two-dimensionally correcting the lips of a subject based on preset reference by setting a plurality of points for determining the form features of lips on an image that depicts the lips, and judges the form features of the lips of the subject based on analytical values of the two-dimensional features of the lips measured from the set points.

Abstract: The present invention provides a cosmetic that contains glycerin modified on both ends with silicone represented by the following general formula (a). In this formula, R1 denotes a straight chain or branched alkyl group having 1-12 carbon atoms or phenyl group, R2 denotes an alkylene group having 2-11 carbon atoms, m is 10-120, and n is 1-11. The object of the present invention is to provide a cosmetic that contains glycerin modified on both ends with silicone and is superior in terms of the sensation during use and the powder dispersion stability.

Abstract: A classifying method according to an eye form considers the eye form feature as an important factor, to provide an eye cosmetic treatment method for appropriately and quickly making up the eye so that the eye balances and looks large and attractive according to the type categorized by the classifying method. A makeup tool is devised by integrating an eye form feature analyzing method with a form shaping method by markup. An eye form classifying method uses as indexes, three forms, namely, the eye frame form showing the shape of the eye contour, the eye form showing the three-dimensional shape of the eye, and the angle form of the inner corner and outer edge, the eye forms are classified. The eye forms are classified by comparing the eye form with the eye form of a reference balanced eye.

Abstract: The objective of this invention is to provide an oily external composition for skin having an excellent rough skin recovering/preventing effect, and wherein powder is well dispersed in oil. An oily external composition for skin of this invention is characterized in that comprising a complex powder (the surface of lipophilic base powder is covered with zinc oxide) and an oil component, wherein said complex powder is dispersed in said oil component, and wherein zeta-potential of said lipophilic base powder is negative value at pH on skin. It is preferable that zeta-potential of said lipophilic base powder is ?10 mV or less at pH on skin. It is preferable that said lipophilic base powder is swelled in the condition of dispersing in oil. Above-mentioned external composition can be used as a rough skin recovering composition and a sensitive skin caring composition.