Abstract: The present invention provides a pigmentation skin model that comprises: a first cell group containing fibroblasts damaged by light irradiation, said first cell group being seeded on a first cell culture substratum; and a second cell group containing melanocytes and keratinocytes, said second cell group being applied onto the first cell group. The present invention also provides a method for producing the pigmentation skin model, and a method for evaluating a factor for treating or preventing pigmentation of the skin, said method comprising using the pigmentation skin model.

Abstract: A water-type or oil-in-water type cosmetic provided with a watery feeling in use and high ultraviolet protection ability. The water-type or oil-in-water-type cosmetic according to the present invention is characterized by containing (A) a porous spherical powder having an average particle size of 1 to 4 ?m and an oil absorption rate of 160 ml/100 g or lower; and (B) an ultraviolet absorption agent.

Abstract: An emulsion-type cosmetic composition contains from 3 to 50% by mass of an oil-soluble UV absorber, and from 0.2 to 20% by mass of a powder containing a polymer powder. An average IOB value of a monomer or monomers constituting the polymer powder is from 1 to 10.

Abstract: An ultrasonic measurement method includes irradiating an object to be measured with an ultrasonic wave, acquiring a reflection wave from the object, calculating at a processor an acoustic impedance in a depth direction of the object from the reflection wave, and estimating and outputting a thickness of the object based upon an inflection point determined by second-order differentiation of the acoustic impedance.

Abstract: The purpose of the present invention is to provide, in an emulsified base containing at least 5 mass % of water and a higher alcohol content, a hair cosmetic which imparts a desired shape, smoothness, and water repellency to hair and has excellent retention of this effect. The present invention relates to a hair cosmetic and a hair treatment method using the same, the hair cosmetic being characterized by containing: (A) a copolymer having, in a main chain thereof, a polysiloxane structure and a polyoxyalkylene structure, and having, in a side chain thereof, a trialkoxysilane group or a silanol group; (B) a surfactant containing one or two or more of (b-1) cationic surfactants in an amount of 2.0 mass % or less; (C) a higher alcohol; and (D) at least 5 mass % of water.

Abstract: The present invention provides: a composition for reconstituting human skin tissue having hair follicles, the composition characterized by containing human epidermal cells and human dermal cells, the human dermal cells containing cell groups of human hair papilla derived from non-embryos via spheroid formation; and a human skin tissue model animal to which said composition is applied. The invention also provides a method for producing said composition and animal.

Abstract: The object of the present invention is to provide a cosmetic capable of giving high SPF values while maintaining feeling on use required for oil-in-water cosmetics, such as freshness and being easy to spread and reducing burden on the skin. A cosmetic containing a powder dispersion composition prepared by dispersing powder, wherein the powder has an average particle size of 10 times or less the primary particle size of the powder, the polydispersity index (PDI value) of the average particle size of the powder dispersion composition is 0.4 or less and the absorbance per 1% of the powder is 150 or more.

Abstract: The object of the present invention is to provide a powder dispersion composition capable of giving high SPF values while maintaining feeling on use required for oil-in-water cosmetics, such as freshness and being easy to spread and reducing burden on the skin. A powder dispersion composition prepared by dispersing powder, wherein the powder has an average particle size of 10 times or less the primary particle size of the powder, the polydispersity index (PDI value) of the average particle size of the powder dispersion composition is 0.4 or less and the absorbance per 1% of the powder is 150 or more.

Abstract: The purpose of this invention is to find a novel fragrance component effective for prevention or control of swelling, lymphedema, skin aging or obesity from the viewpoint of activation of lymph vessel function by promotion of the expression of VEGFC. This invention provides a swelling improving agent, lymph vessel activator and VEGFC production promoter characterized by containing one or a plurality of components selected from the group consisting of rose oxide, citronellyl acetate and niaouli oil.

Abstract: An oil-in-water type emulsified cosmetic and a method of making can be prepared in a system not containing a silicone and is surprisingly produced without a wet-type dispersion apparatus by using a specific combination of the oil component constituting the oily phase and a hydrophobizing agent for a hydrophobized powder. The composition includes an aqueous phase; an oily phase dispersed in the aqueous phase; and a powder dispersed in the oily phase. The oily phase comprises (a) volatile hydrocarbon oil and (b) non-volatile hydrocarbon oil in a combined amount of 40% by mass or more with respect to the total oil content, wherein the blending ratio of (b) non-volatile hydrocarbon oil to (a) volatile hydrocarbon oil, [(b)/(a)], is within a range of 0 to 2.5, and the powder comprises a powder having a surface hydrophobized by a treatment with a metallic soap consisting of a higher fatty acid and a divalent metal or a composite treatment with a higher fatty acid and a divalent metal hydroxide.

Abstract: An oil-in-water emulsion composition for skin includes 0.2 to 2.5% by mass of polyisobutene having a relative mass in a range of 30,000 to 100,000. The composition is applied to skin except for a lip.

Abstract: A discharge container 1 includes a container body having a discharge face 13, on which a discharge hole 15 is formed, a cylinder part including a discharge space 2 in communication with the discharge hole 15 inside the container body, a piston 3 movable between a first position and a second position, the second position being farther than the first position from the discharge face in the discharge space 2, and a plurality of storage portions 5a to 5e for storing contents, wherein a plurality of inlet holes respectively corresponding to the plurality of storage portions 5a to 5e are formed in an inner wall of the discharge space 2, wherein, when the piston 3 is at the second position, the plurality of inlet holes 22a to 22e communicate with the discharge space 2 between a top face of the piston 3 and the discharge face, and the contents are ready to flow into the discharge space 2 from the plurality of inlet holes 22a to 22e, and wherein, when the piston 3 is at the first position, the plurality of inlet holes

Abstract: The purpose of the present invention is to provide an oil-in-water emulsion cosmetic that is thickened using an associative thickener containing a hydrophobic modified polyether urethane, that stably holds a hydrophobization powder in an inner oil phase, and that does not release water even after long-term storage, without a reduction in usage sensations regarding moistness, resilience, and smoothness originally possessed by the oil-in-water emulsion cosmetic. The present invention is an oil-in-water emulsion cosmetic characterized by comprising (A) a hydrophobic modified polyether urethane having a specific structure such as polyurethane-59, (B) a polyether modified silicone having an HLB (Si) of 5-14, and (C) a hydrophobization powder. The cosmetic according to the present invention preferably further comprises (D) a lower alcohol and/or a polyol, and/or (E) a nonionic surfactant having an HLB of 8-18.

Abstract: The purpose of the present invention is to provide an aqueous hair cosmetic which contains a lower alcohol such as ethanol and water and is used by spraying in the form of a mist, wherein the hair cosmetic imparts a desired shape, smoothness, and water repellency to hair and has excellent retention of these effects. The present invention relates to a hair cosmetic characterized by containing: (A) a copolymer including a polysiloxane structure and a polyoxyalkylene structure in a main chain, and a side chain having a trialkoxysilane group or a silanol group; (B) a cationic surfactant; (C) a lower alcohol; and (D) water, and a hair treatment method using the same.

Abstract: The purpose of the present invention is to provide a hair treatment method that permits a suitable amount of a component having a hair treatment effect to be deposited uniformly on the hair, and that has exceptional persistence of effects in which hydrophobicity, combability, and smoothness is restored by appropriate heat treatment to hair that has been damaged and in which these effects can be maintained for an extended period of time. The present invention pertains to a hair treatment method characterized by including: (1) a step for applying, to hair, a hair treatment agent containing a copolymer that includes a polysiloxane structure and a polyoxyalkylene structure in the main chain, the copolymer having a side chain that has a trialkoxysilane group or a silanol group; (2) a step for subjecting the hair to heat treatment at 40-230° C.; and (3) a step for rinsing the hair.

Abstract: A non-sticky body surface patch is provided, which is attachable on a body surface to add a look of fullness to the body surface, exhibits excellent followability to skin deformation, and imposes little burden on body surfaces and thus is widely applicable to body surfaces. The non-sticky body surface patch includes a silicone rubber having a thickness in the range from 50 to 600 ?m, wherein the silicone rubber consists of a silicone rubber composition having a rubber hardness of 20 or less measured with a Type A durometer as defined in JIS K6249 standard.

Abstract: A hair dye that is safe for human bodies and has a high hair dyeing effect is provided. The hair dye consisting of: a reaction solution (A) comprising: a substance having a specific flavonoid skeleton represented by the following general formula (1); one type or two or more types selected from benzyl alcohol, vanillin, propylene carbonate, and ?-butyrolactone; and one type or two or more types selected from a thioglycolic acid salt, a thiolactic acid salt, cysteine and cysteamine, and a reaction solution (B) comprising an oxidizing agent. (In the formula, R1, R2, R3, R4, R6, and R7 independently represent a hydrogen atom, a hydroxy group, or a methyl group; either one or both of R6 and R7 is/are a hydroxy group; R5 represents a hydrogen atom, a hydroxy group, a galloyl group, or a saccharide; and X represents >CH2, >C?O, or >CHOH.

Abstract: An ultrasonic-image-construction apparatus can construct an ultrasonic-tomographic image of a thin, layer-structured target object to be measured relatively easily and highly accurately in a manner in which such layered structure is easily understood. An ultrasonic transducer of an ultrasonic-image-constructing apparatus transmits ultrasonic waves to the target object. A reference substance makes contact with a base substrate, with such ultrasonic waves being incident on the target object via the base substrate, then receives an impulse response of an ultrasonic waveform. A computing means performs calculation to estimate acoustic-physical-property distribution in consideration of the multiple-reflections influence based on normalized-impulse information obtained from impulse-response information of such ultrasonic waveform incident on the reference substance and from impulse-response information of such ultrasonic waveform incident on the target object.

Abstract: An emulsion cosmetic maintains a concealing ability, allows light in a long wavelength region to transmit efficiently (i.e., an excellent red light selective transmit function), is spread easily, wherein a powder likeness cannot be felt upon use, and provides a natural finish when applied onto the skin. A titanium dioxide powder therefore is composed of particles having an apparent average particle diameter of 100 nm or more and less than 500 nm, an average crystallite diameter of 15 to 30 nm as measured by a X-ray diffraction method and a specific surface area of 10 to 30 m2/g, and each has a shape with radially projected needle-like projections are coagulated, and has a ratio of a longer axis to a shorter axis (i.e., a (longer axis)/(shorter axis) ratio) in the shape of 1.0 to 2.5. The emulsion cosmetic contains 0.1 to 25% by mass of the titanium dioxide powder, 0.1 to 5% by mass of disteardimonium hectorite and 0.1 to 8% by mass of a silicone surfactant.

Abstract: A dispensing container capable of changing the ratio between the amounts of two kinds of contents to be dispensed, includes two container bodies, two pumps including two stems, an adjusting member configured to press the stems and to be rotatable about an axis extending in a substantially vertical direction, and a pressing head configured to, in response to a depressing operation, rotate about an axis extending in a substantially horizontal direction, to thereby depress the stems via the adjusting member. The adjusting member includes a plurality of pressing portions against which the stems are pressed, and when the adjusting member is rotated about the axis, a depressing stroke of the one of the plurality of pressing portions on the side of one of the stems becomes shorter, and a depressing stroke of the other one of the plurality of pressing portions on the side of the other stem becomes longer.